RCPedia: Rtcs

Summary

Retrocopy Name	RPS6P10	Plot displaying the genomic locations of a retrocopy (in scaffold_m13_p_3) and its respective parental gene (in scaffold_m13_p_3). Each line represents a retrocopy.
Species	Rousettus aegyptiacus
Coordinates	scaffold_m13_p_3:35389242-35389692 UCSC
Strand	+
Parental Sequence	RPS6_x1
Parental seq. overlap	360 bp
Parental seq. overlap (%)	3.7%
Genomic Region	Intergenic
Retrocopy Summary	RPS6P10, located on scaffold_m13_p_3:35389242-35389692, is a retrocopy of the parental gene RPS6. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name	RPS6
Full Name	N/A
Also known as	NULL
Coordinate	scaffold_m13_p_3:60473896-60486004
Strand	-
Gene summary	N/A

Homology

Species	Scientific Name	Retrocopy
Human	Homo sapiens	RPS6P12
Bonobo	Pan paniscus	RPS6P8
Gorilla	Gorilla gorilla	LOC101131142P9
Orangutan	Pongo abelii	RPS6P9
Gibbon	Nomascus leucogenys	RPS6P1
Rhesus	Macaca mulatta	LOC712274P19
Golden snub-nosed monkey	Rhinopithecus roxellana	RPS6P24
Dolphin	Tursiops truncatus	RPS6P8
Horse	Equus caballus	RPS6P6
Dog	Canis familiaris	RPS6P2
Panda	Ailuropoda melanoleuca	RPS6P30
Greater mouse-eared bat	Myotis myotis	RPS6P39
Chimpanzee	Pan troglodytes	Without Homology
Green monkey	Chlorocebus sabaeus	Without Homology
Crab-eating macaque	Macaca fascicularis	Without Homology
Baboon	Papio anubis	Without Homology
Marmoset	Callithrix jacchus	Without Homology
Mouse lemur	Microcebus murinus	Without Homology
Mouse	Mus musculus	Without Homology
Rat	Rattus norvegicus	Without Homology
Chinese hamster	Cricetulus griseus	Without Homology
Rabbit	Oryctolagus cuniculus	Without Homology
Pig	Sus scrofa	Without Homology
Cow	Bos taurus	Without Homology
Sheep	Ovis aries	Without Homology
Cat	Felis catus	Without Homology
Pale spear-nosed bat	Phyllostomus discolor	Without Homology
Velvety free-tailed bat	Molossus molossus	Without Homology
Kuhl's pipistrelle	Pipistrellus kuhlii	Without Homology
Greater horseshoe bat	Rhinolophus ferrumequinum	Without Homology
Sloth	Choloepus didactylus	Without Homology
Tasmanian Devil	Sarcophilus harrisii	Without Homology
Opossum	Monodelphis domestica	Without Homology
Platypus	Ornithorhynchus anatinus	Without Homology
Chicken	Gallus gallus	Without Homology
Turkey	Meleagris gallopavo	Without Homology
Zebra Finch	Taeniopygia guttata	Without Homology
Budgerigar	Melopsittacus undulatus	Without Homology
Painted Turtle	Chrysemys picta	Without Homology
Lizard	Anolis Carolinensis	Without Homology
Frog	Xenopus tropicalis	Without Homology
Zebrafish	Danio rerio	Without Homology
Drosophila	Drosophila melanogaster	Without Homology

Expression

Related Sequence

>RPS6P10
ACAAGGCTTCCCCATGAAGCAAGCTATTTTGACCCATCACTGTGTCTGCCTGCCACTGGGTAAGGGGCATTTCTGTTATAGGCCAAGGATAACTGGAGGAAGGAAACACAAATCTTTTTAACGTTCCATTGTAGATGCCGCTGAGTGTTCTTAACTTGGTCGTTATTTTTAAAAAAGGAAAAGGATATTCCTGACTTACTGGTAACTATTGTGCCTTGTTGCTATATGAACGTGCAAATGTTCAGTATTGCTAAAGAAGATGATGTTCGTCAGGGTGTTGTGAGAAAGCCCGTGAATAAGGAAGTTAAGAAACCCAGGATTAAAGTGCCCGAGATTCAGTGTTTTGTTATCTCACGTGTCCTGCAACACACACATGAGTGTATTGCTCTGAAGAAACAGTGTACTAAGAAAAATGAGGATGAGGCTATAGATTTTGGTAAACTTTTGGCCA

>RPS6_x1
accatcccttttcatccctgtatctccagcccctaacctggtgctgacataaagtaggtgctcggtacatgtttgttgagtgaTATTGAAGATCCTCCCATGGCTGTTCCCTGTCCGAATTAATCCAGAACACCTCAGCACCAAGGTCAGGCTTCCATCTCCTCCTCGTAGTGAGGTCAGCTTGGGTCAAACTCCTAGGGAAATACTTCCAAAAGCAGCACAACTTAAAACAGATGGAGAGGACATGGGTCATGACAGCGATGATGATGTGGTAGGGAGGATGGGAATAGCTAACATTCACTGAAAGTCTACTGTGCACCAGGAAGTGTTTAACTTTTTTGGCATATTAGTTCATTTATCTCTGACAAGAACTGTATTAGGAAAGTATTGTCACCATTTTAAGATGGAGAAACAAAGGCACAAGGAGAGCAAGTAAGTTGTCCAAGGTCACATAGCTATTACGGAATGAAAATACATGGGACAAAAGAAGATTGCCCTGACACATGACTTGATCTGATTTaaaaaaaaaaaaaaaaaaaaaaaaaGATTTATTCTTGCACTCTTTCTGTCATCCCCTTTCCTTCCTGCCCTCCACGAAATATTTCATAATTATATGCTGGAGCTTATTTTCAACAACTCTGTAAAAACATCCCTTAGTCCCTGACCCGAGGGGTGAGAAATCCATTGTAATTCTTGCTCCTGAATACAGTTACAGAAATAATGCCAAGGAGTTTTCCTAGCTTCATTCCTTTGGTTTAACTTCCTTCCCCAAACACAGTGTGGCATATTTTAAAAATTAGTTTCTTCCTACAAATAGAAATTGCCCTTGACATTTAGTTTTTTGTGTCTAAGGTGATCTTTTTTCTTGTTTCCTTGACCTCAGCCAAATATGAAACAGCTTACTAACATGCACAAACTCATTTCCTCCTTTACTATTTATCTTCCTTTCTGTATTTATACCTCTTTTTGGAAAATATCCCTTTTCTCAAACATACTTGAAAAACTTATTTACCAGTGAGTGAGGGAAAATTTTTACCTTTACTGATTGCTTCTAGAATTACTTTAACTTAATGTTATTGAATACAAAAATGTATTGTTTAGTCAGGATCCTTGTTGTTGAGAGATTCCACCTTTGGGCCCTGTTATAAGCTGAATTGTGTCCTATCCCAGCTCCTCCCCCCATCCCAATTTTTATCTTGAAGAatatcttgaggtcctaacccccaatacttcagaatgtgactgcatttggagatagggtctttaaaggggtaattcagttaaaatgaggttatgagggtgggccctaatccaataggactggtgtccttataaaaagaggagagtagggcacagacacacacagagggaagaccatgtgaagaaacagagagaagatggtcatctgtaagctaaggaagggcctcagaagaaaccagtcctgccaatatcttggtctcaaacttctagctccaaaactatgagaaaataaatttccactatttagccacccagtttgtggcactttgttataggagccctaccaaattaatacaGGCCCCTGCTCAAAGCCCACCTCTTTTACTGTGTCAAATGCTCAGCCTCCAAGCCCATATACCCAACAACCTattagatgtctctacttgtatatcccatagacacttcacactctgtctccaaaatatctccccatttcccccaccccctgcccctggcaatcatgattctaatttctgtttctatgagtttagcactgttttttgtttgtttgtttgtttgtttgttttagattccacatgtgagattataaagtatttgtctttcttcgtctggcttatttcacttagcataatgtcctcaaggtccatccatgttgtggcaaatggcagaatttcctttttatggctgaataatattccattgtatcatatacttttcctttattcatttatccattgattggacacttaggttgtttccatgtcttggctattgtgaataatgctgcagtgaacatggggttacagatatctGtgttagttccccaggctgatgggattacttccagaatcacagtcttgttaggttggtgccagtaataagaatattactgggtctgcagtggtgtccatggtcaaggggcttgttaccaggggcttggaccagcgtggatcccatctggtccctggtagtatgtgactgccatcattactttgttcagtagggtgatgctagaacaaacgttcgcttcaggcatcacagcagggtcctctgacagcctgttaccaggtgtgtggatgtagttcccaccaggtctgtgggaggacctggtaatcggatagatccctgagtggtcagaactggctatggactgtggccgagaaggcctaaaatggaggcccatgcctgtgtcaggtttcacagccaacactgaggtctgcagacctggctctggaggcatgaattggcatttctcctgccaggtccctggatgggctgaactgctccatgaccatggctagagaagcctgaggcaagcatagggccctttcaggatttccaggtgACAAAAGGAGTGTTTTCTGTTGGTCCTTGGAaaaccagagggcaactgagtccggggctgtgctgcctgtgccactcagccaatagaccgacacgggagttgggatatttacaataagtgtttattgtcagagcacaagtgatcttagaaggcaacgggttaacaccttcaaaaactgccttgcattctcagtccggcttaggggtatttaagggaaaatctgggcattaatccagggggcccattatgcttcacagagccggagccattcctctgacaacatggtcctctggtggcatcagtaacccaggaacaaaggtgggaatagtctggaaagaatgctagaccagaaagattgtgatcagtaaacataagggaattaatcataagtttcagggcaaatttctatggcaggggacattccaagctctgggtcaagccaccggggacagtctgttgttaagctatcagacaaggaaaagtgaagccaggaatgctgtgaggtttctaccaccgggggcccaatggggcccttcttcaTTTGTGCTAACAGGACTGTTTGAGGATTACAGCTAGGACAGGCTGGAGCTCAGTTACGGGGCCGTTTCAAAACCTACATTTTGACCAAGTTTAGTAGGCTTTCTTTCAGGggctcccaggtcacagccgaatggctggagccaattcatgtgccacttcagagtccgcagccaggaccgaagtttgtgtgcttactacccaatacacaggtggacatgactcctcctggatcccctagcacatggtgctggtgacagaaccaaagctaaatggggccgtagccaagtcctcaggtttttggagctgtttctaggtctgtagctccaaccatggtaggcagttcagctacttggggggcaggcctgcctccttctcaaaactgctctcctgggtcttggactgcacagggatttcacaatctacctggatctcaaagttctcccaaaggcatttttgtccctggatagatgccaaattattgttggtggggggactatgagcaagggatatcttactctactaactcattgttaccactTAAGAATTCCTTTTATAAAATTTTGACTTCTATATAAAGTTATAAATATTCTTAAAAATAGGATAAAAAAGAAAACCATAAATTTTatatgtagatggccctctgtatctgtgggttctgccttcacagattcaactatccgcagatcaaaagtatttgaaaaaaaatgttaagttgttgctggtgcatactatgtagttaggcctacaatggctacatctgtactgaactctttttttttcttatcattattccctaaataatacagtgtaacaactatttacatagtgtttccattgtattaggtattataagaaatctagagatgatttataataggcatacctcagagttattgtgattttgattccagaccaccacaataaaatgaacatcacgataaagtgagtcacatgatttttttggtttaccagtgcatataaaagttatgtttccactgtaccatagtctaactaaatgtgcaatagtgttacatctaaaaaaaaaacaatgtgtataccttaatttaaattttttttaaaaaatgccaaccatcatctgagccttcggtgagtcataatctttttgccagtggaaagtgttgcctcagtgttggctgctgactgatcagagtagtagttgctgaaagttggggtggctgtggcaatttcttaaaataatacaacaattaagtttgtactattgactcttcctttcacctatgacttctctgtagcatgtgatgctgtttgatagcattttatccacaatagaacttctctcaaaattggagtcgaccctctcaaaccctgccgctactttatcaactaagattatgtaatattccaaatcctttgttgtcatttcaagccttcatagcaacttcaccagtagattccacctcaagaaaccactttctttgttcatccataagaagcaactcctcatctgtgaaagttttatcataagattgtaggaattcagtcacatcttcaagatcaacttctacttctacttgctatttctacaatatctgcatttacttcctccaccaaacttttgaacccttcaaacttatcaatgagggttgaaatcaacttcttccaaactctcattaatgttgatattttgacctcttcccatgaatcacaaatgttcttaatggtatcaggaatggtgaatcccttccagaaggttttcaatttactttgctcagactcatcagaggaatcgctaactatggcagttgtagccttgtgaaatgtatttgttaaataagacctggaagtttaaattactccttgatccatgggctgcagaatggatgctgtgttagcaggcatgaaaacataaatctcattgtacatttccatccgagctctcgggtgaccaggtgcaatgtcaatgagcagtaatattttgaaagggatctttttttctgatcagtgggtctcaacagttagcttagaatattcagtaaaccatgttgtaaaagatgtgccatcatctaggctttgttgctccatttacagagcactggcagagtcaatttagcataattcttaagggccctaggatttttggaacggtaaatgaacattggctttaccttaaactcaccaggtgcattaccccctaataagagagtcaggttgtcctttcaaactttgaaaccaggcattgacttctctctagttatgaaaagttctaagtagcatcttcttccagtacaaggctgtttcatctacattgaaaatctgctgttcagtgtagccaccgtcattaattatcttagatcttctagataacttgctgcagcttctacatcagcagttgatgcttcaccttgcacttttgtgttatggagacagcttctttccttaaacctcatcaagctctgctaacttcaaacttctgcagctttcttacctctctcagccttcatagaattgagagttagggccttgctctggattaggatttggcttaaaggaatgttgtggctggtttgaaacattcctcagcagatgaatgaataagcaaagtacggtatacatatacaatggattattttcagctttgaaaaggaaatcctgtcacatgctacacaacatgggtgaaacttgaggacattatgctaagtgaaataagcttatcacaaaaagacaattattgtatgattccatttatatgaagtgcctgaagtagtaaaattcatagaaacaggaagagggatggctaccaggactgggggtgtggggaagggtgttatttttaatgggtatacagttctagttttgcaagatgaaaaagttagggagatctgtttcacagcaatgtgaatatgcttaacactacggaacttgtatatgtaaaattggttaaATATTATGTTTTTATCATATAAATAAAATGCATAAAAAAAAGAGAAAGAAACCTGAGCAATAGTCCTGGACTTTACTCTTTGCCTCATATAAACTTACTACCACTATGTcaataaaaaataaacagagctaaaaaaaaatgggcaaaggactggaacagacatttctccagaagagatatacaaatggccaacagataaataaaaagatgttcaacatcattagtccttagggaaatgcaaatcaaaaaccataatgaggtatcactttacactcactaggatggctataatttaaaaagaaaataacaaaataagttttgaccaggatatgaagaaactgtactcctcatacattgctggtggaaatgtaatatggttcagctgctgtgaaaatagtttggaattcttccaggagttaaacacagaattaccacatgacccagcaattccactcccaggtatatacccaaaggaattgaaaacaggtactgaaacatgccagcactattcacaatagtcaaaagttggaaacagccaaaagtccatcaatggatgaatggataaaaatattgtggtctatgcatagtggaaaattattcaattataaaaaagaatgaagtattgatatatgctatacaacatgacgaatttgaaaaaaatattagaagccaggtcaggttacatattgattaattctatttacctgaaatatatagaataaataaatccatagagacaacacagactacttgataggtgaggtgaatggggagcaattgctgcaataggtataggatttcctttggggataatgaaaatgttttggaactagatagaggtggtgtttgcacaatattgtgaatgtactaaatgccatttaattgtccacttaaagtgattTTGTTATTTTGCTACAACAACAAAAAAATTATATATGCAAGTTTTAAATgcatttcaccaacattctatatattaacaacaggtgatcaaacaggattagtagaatctttcaactttgaatgtgaagcagacctaagctgaaaatattatgatactaaagcaaatcaaagggatgtaatAACCTTGGAAAGCAAAAATTATTTTTATTTACTTGAAATGCAGTTCTCTTGAAAAAAAATGTAATAGGCAATAAATGTTCTTTCTTTCCAAGTATTGATTGAGAGTGTGGGGTACAGTTAGATCACACGAGTTCGCATTCTCCCAGGCATGTTCTGGAAGACTATCAAATGCATTGTATCTTTCCCACATCTTTCTGTACTAAGAGTTGCATCATTGTTGATTCAAAATTTACCACATACATCCACTTTTCCCTCTGCTGGCTGCCTCCATACTACCACACTCTAATGGACTAAATCTACCAGAGCTGGGGTTATAACCATTTAAAAATATTTACTAAGCATTTATGTATTATGTGCCATACACTTTCCTGGGTTCTGAGTATATCATAGTAAAGACTTAATTTTTCATCTAGTAGAAAGACCATGAACAACCTATTTATATATCATGATTAAGTACTGTAAAATAGTGCTATACCAGAGAATGAGAGGGATATTATTTGAGGCAGTGTTATCAGGCAAGGTTTCTCTTAGGAGGGATATCTAACCCGAAAGACTTGCATGGCATTAACCAACGGCAGTAGTGAGTTTGGGACTGTGTAAAGCTTTTTTTAAGGCCAGTACACTTTTCAAGCTAGCGTTACAGGGCGGCAAAGGATATTATTCTGTGACAGAACAACAATGACTACAGACCGGTTACAGGACAAGCGATGCTCGAGTATTTAAGGGAAAAACAAATAAGGTTTTCGGGGTGTCTTGCTATGACTGCCAGAATTAGGGCGGGCAAGACACGTTCCCGAAATGAAAATCTTCCAACGGAGTCTGAACTACAGGAAAGCCTAAGCGAGCTGAACTCCGGTCTCAGTCTCTTCCTTGGGTAGTATCAAAGGTAGAGTGTCAGACATCGAACTGGGGCTCCGCCCTAGCCCACGGGAACGTGGAAAACCTCAGGCAGGGACGAGTCTAACCTTCCGAGGTGAACCTGTGCCACAGACGGTGCTGACTCGCGGATTACCAGAACCCTCCACCTGACTGCTGGTTATCTCCACCCCCGGAAGTGCCTCCAACCCGATTACTTCCGCTATGCCAGGATTTTTTTTTTTTTGTCTCGCGAGAACTGAAAGTGTCTATGTGATCTCTAAGCGGAAGTCAGGCCTCTTTTTCGTGGCGCCTCGGAGGCGGTCGGCTGCTTCAGGATGAAGGTACGAAATGGTAGCGGGTGTTGAACTAGGCTTGGGGTGCGTCCATCGTACCCCAAAACACGGTGTTGCCGCAGTGGTAGCTCGCCAAAGCCTTGGCTCTAGGTAGAGAAGGGTCTGCGGTAGGAGGAAGCTCGCCCTTAATAGGGCCGGAGCTTCTTGGGAAAGTGGATGGCGAGAGATTGCTGCTGGAGCCGGGCCATGTCGGGAGGCCATGGTGGCGTCCGGACAGATGCGGCCATACTGGCCAGTTGGCGTCCCACGGGTTGGGTTCCTTACTCCGAGAGAGGGTGAATGGCAGCAGATCACCCTTCGCCCCAGCTCCTCCGCAGGGCTTGGAAAAATGTGTCCTATTTTTAGTGCGGTGTTTCTTGCGCGTAATTATGCACACGTGCTTCAGTGAATAAAATCAATATTTCAAGTTTTCTGATTGTATGGAGGTGACATGAAAGGATTTTTGCAATGGAATGCTTTTGTAGGTGGTTCTGCAGTTTTCGTAAAGCTCTTTTTTCCCCCCTGCCCCGCTTAAATTCTTAGCTGAACATCTCTTTCCCAGCCACTGGCTGCCAGAAGCTCATTGAAGTGGACGATGAACGAAAACTTCGTACATTTTATGAGAAGCGTATGGCCACAGAAGTTGCTGCTGACGCTCTGGGTGAAGAATGGAAGGGTTATGTGGTTCGAATCAGTGGTGGAAACGACAAGCAAGGTTTCCCCATGAAGCAGGGTGTCTTGACCCATGGCCGTGTCCGCCTGCTACTGAGTAAGGGGCATTCCTGTTACAGGCCAAGGAGGACTGGAGAAAGAAAGCGCAAATCTGTTCGGGGTTGCATTGTGGATGCCAATCTGAGTGTTCTCAACTTGGTCATTGTGAAAAAAGGGGAGAAAGATATTCCTGGTCTCACTGATACTACTGTGCCTCGTCGCCTGGGGCCCAAAAGAGCTAGCAGAATCCGCAAACTTTTCAATCTCTCTAAAGAAGATGATGTCCGCCAATACGTTGTGAGAAAGCCCCTAAACAAAGAAGGTAAGAAACCTAGGACCAAAGCACCCAAGATTCAGCGTCTTGTTACTCCACGCGTCTTGCAGCATAAACGTCGGCGTATTGCTCTGAAGAAACAGCGTACTAAGAAAAATAAGGAAGAGGCTGCAGAATATGCTAAACTTTTGGCCAAGAGAATGAAGGAGGCCAAAGAGAAACGCCAGGAACAGATTGCCAAGAGACGTAGACTTTCCTCTCTGAGAGCTTCTACCTCTAAGTCTGAGTCCAGTCAAAAATGAGATTTTGTAAGAGT

>RPS6_x1 

accatcccttttcatccctgtatctccagcccctaacctggtgctgacataaagtaggtgctcggtacatgtttgttgagtgaTATTGAAGATCCTCCCATGGCTGTTCCCTGTCCGAATTAATCCAGAACACCTCAGCACCAAGGTCAGGCTTCCATCTCCTCCTCGTAGTGAGGTCAGCTTGGGTCAAACTCCTAGGGAAATACTTCCAAAAGCAGCACAACTTAAAACAGATGGAGAGGACATGGGTCATGACAGCGATGATGATGTGGTAGGGAGGATGGGAATAGCTAACATTCACTGAAAGTCTACTGTGCACCAGGAAGTGTTTAACTTTTTTGGCATATTAGTTCATTTATCTCTGACAAGAACTGTATTAGGAAAGTATTGTCACCATTTTAAGATGGAGAAACAAAGGCACAAGGAGAGCAAGTAAGTTGTCCAAGGTCACATAGCTATTACGGAATGAAAATACATGGGACAAAAGAAGATTGCCCTGACACATGACTTGATCTGATTTaaaaaaaaaaaaaaaaaaaaaaaaaGATTTATTCTTGCACTCTTTCTGTCATCCCCTTTCCTTCCTGCCCTCCACGAAATATTTCATAATTATATGCTGGAGCTTATTTTCAACAACTCTGTAAAAACATCCCTTAGTCCCTGACCCGAGGGGTGAGAAATCCATTGTAATTCTTGCTCCTGAATACAGTTACAGAAATAATGCCAAGGAGTTTTCCTAGCTTCATTCCTTTGGTTTAACTTCCTTCCCCAAACACAGTGTGGCATATTTTAAAAATTAGTTTCTTCCTACAAATAGAAATTGCCCTTGACATTTAGTTTTTTGTGTCTAAGGTGATCTTTTTTCTTGTTTCCTTGACCTCAGCCAAATATGAAACAGCTTACTAACATGCACAAACTCATTTCCTCCTTTACTATTTATCTTCCTTTCTGTATTTATACCTCTTTTTGGAAAATATCCCTTTTCTCAAACATACTTGAAAAACTTATTTACCAGTGAGTGAGGGAAAATTTTTACCTTTACTGATTGCTTCTAGAATTACTTTAACTTAATGTTATTGAATACAAAAATGTATTGTTTAGTCAGGATCCTTGTTGTTGAGAGATTCCACCTTTGGGCCCTGTTATAAGCTGAATTGTGTCCTATCCCAGCTCCTCCCCCCATCCCAATTTTTATCTTGAAGAatatcttgaggtcctaacccccaatacttcagaatgtgactgcatttggagatagggtctttaaaggggtaattcagttaaaatgaggttatgagggtgggccctaatccaataggactggtgtccttataaaaagaggagagtagggcacagacacacacagagggaagaccatgtgaagaaacagagagaagatggtcatctgtaagctaaggaagggcctcagaagaaaccagtcctgccaatatcttggtctcaaacttctagctccaaaactatgagaaaataaatttccactatttagccacccagtttgtggcactttgttataggagccctaccaaattaatacaGGCCCCTGCTCAAAGCCCACCTCTTTTACTGTGTCAAATGCTCAGCCTCCAAGCCCATATACCCAACAACCTattagatgtctctacttgtatatcccatagacacttcacactctgtctccaaaatatctccccatttcccccaccccctgcccctggcaatcatgattctaatttctgtttctatgagtttagcactgttttttgtttgtttgtttgtttgtttgttttagattccacatgtgagattataaagtatttgtctttcttcgtctggcttatttcacttagcataatgtcctcaaggtccatccatgttgtggcaaatggcagaatttcctttttatggctgaataatattccattgtatcatatacttttcctttattcatttatccattgattggacacttaggttgtttccatgtcttggctattgtgaataatgctgcagtgaacatggggttacagatatctGtgttagttccccaggctgatgggattacttccagaatcacagtcttgttaggttggtgccagtaataagaatattactgggtctgcagtggtgtccatggtcaaggggcttgttaccaggggcttggaccagcgtggatcccatctggtccctggtagtatgtgactgccatcattactttgttcagtagggtgatgctagaacaaacgttcgcttcaggcatcacagcagggtcctctgacagcctgttaccaggtgtgtggatgtagttcccaccaggtctgtgggaggacctggtaatcggatagatccctgagtggtcagaactggctatggactgtggccgagaaggcctaaaatggaggcccatgcctgtgtcaggtttcacagccaacactgaggtctgcagacctggctctggaggcatgaattggcatttctcctgccaggtccctggatgggctgaactgctccatgaccatggctagagaagcctgaggcaagcatagggccctttcaggatttccaggtgACAAAAGGAGTGTTTTCTGTTGGTCCTTGGAaaaccagagggcaactgagtccggggctgtgctgcctgtgccactcagccaatagaccgacacgggagttgggatatttacaataagtgtttattgtcagagcacaagtgatcttagaaggcaacgggttaacaccttcaaaaactgccttgcattctcagtccggcttaggggtatttaagggaaaatctgggcattaatccagggggcccattatgcttcacagagccggagccattcctctgacaacatggtcctctggtggcatcagtaacccaggaacaaaggtgggaatagtctggaaagaatgctagaccagaaagattgtgatcagtaaacataagggaattaatcataagtttcagggcaaatttctatggcaggggacattccaagctctgggtcaagccaccggggacagtctgttgttaagctatcagacaaggaaaagtgaagccaggaatgctgtgaggtttctaccaccgggggcccaatggggcccttcttcaTTTGTGCTAACAGGACTGTTTGAGGATTACAGCTAGGACAGGCTGGAGCTCAGTTACGGGGCCGTTTCAAAACCTACATTTTGACCAAGTTTAGTAGGCTTTCTTTCAGGggctcccaggtcacagccgaatggctggagccaattcatgtgccacttcagagtccgcagccaggaccgaagtttgtgtgcttactacccaatacacaggtggacatgactcctcctggatcccctagcacatggtgctggtgacagaaccaaagctaaatggggccgtagccaagtcctcaggtttttggagctgtttctaggtctgtagctccaaccatggtaggcagttcagctacttggggggcaggcctgcctccttctcaaaactgctctcctgggtcttggactgcacagggatttcacaatctacctggatctcaaagttctcccaaaggcatttttgtccctggatagatgccaaattattgttggtggggggactatgagcaagggatatcttactctactaactcattgttaccactTAAGAATTCCTTTTATAAAATTTTGACTTCTATATAAAGTTATAAATATTCTTAAAAATAGGATAAAAAAGAAAACCATAAATTTTatatgtagatggccctctgtatctgtgggttctgccttcacagattcaactatccgcagatcaaaagtatttgaaaaaaaatgttaagttgttgctggtgcatactatgtagttaggcctacaatggctacatctgtactgaactctttttttttcttatcattattccctaaataatacagtgtaacaactatttacatagtgtttccattgtattaggtattataagaaatctagagatgatttataataggcatacctcagagttattgtgattttgattccagaccaccacaataaaatgaacatcacgataaagtgagtcacatgatttttttggtttaccagtgcatataaaagttatgtttccactgtaccatagtctaactaaatgtgcaatagtgttacatctaaaaaaaaaacaatgtgtataccttaatttaaattttttttaaaaaatgccaaccatcatctgagccttcggtgagtcataatctttttgccagtggaaagtgttgcctcagtgttggctgctgactgatcagagtagtagttgctgaaagttggggtggctgtggcaatttcttaaaataatacaacaattaagtttgtactattgactcttcctttcacctatgacttctctgtagcatgtgatgctgtttgatagcattttatccacaatagaacttctctcaaaattggagtcgaccctctcaaaccctgccgctactttatcaactaagattatgtaatattccaaatcctttgttgtcatttcaagccttcatagcaacttcaccagtagattccacctcaagaaaccactttctttgttcatccataagaagcaactcctcatctgtgaaagttttatcataagattgtaggaattcagtcacatcttcaagatcaacttctacttctacttgctatttctacaatatctgcatttacttcctccaccaaacttttgaacccttcaaacttatcaatgagggttgaaatcaacttcttccaaactctcattaatgttgatattttgacctcttcccatgaatcacaaatgttcttaatggtatcaggaatggtgaatcccttccagaaggttttcaatttactttgctcagactcatcagaggaatcgctaactatggcagttgtagccttgtgaaatgtatttgttaaataagacctggaagtttaaattactccttgatccatgggctgcagaatggatgctgtgttagcaggcatgaaaacataaatctcattgtacatttccatccgagctctcgggtgaccaggtgcaatgtcaatgagcagtaatattttgaaagggatctttttttctgatcagtgggtctcaacagttagcttagaatattcagtaaaccatgttgtaaaagatgtgccatcatctaggctttgttgctccatttacagagcactggcagagtcaatttagcataattcttaagggccctaggatttttggaacggtaaatgaacattggctttaccttaaactcaccaggtgcattaccccctaataagagagtcaggttgtcctttcaaactttgaaaccaggcattgacttctctctagttatgaaaagttctaagtagcatcttcttccagtacaaggctgtttcatctacattgaaaatctgctgttcagtgtagccaccgtcattaattatcttagatcttctagataacttgctgcagcttctacatcagcagttgatgcttcaccttgcacttttgtgttatggagacagcttctttccttaaacctcatcaagctctgctaacttcaaacttctgcagctttcttacctctctcagccttcatagaattgagagttagggccttgctctggattaggatttggcttaaaggaatgttgtggctggtttgaaacattcctcagcagatgaatgaataagcaaagtacggtatacatatacaatggattattttcagctttgaaaaggaaatcctgtcacatgctacacaacatgggtgaaacttgaggacattatgctaagtgaaataagcttatcacaaaaagacaattattgtatgattccatttatatgaagtgcctgaagtagtaaaattcatagaaacaggaagagggatggctaccaggactgggggtgtggggaagggtgttatttttaatgggtatacagttctagttttgcaagatgaaaaagttagggagatctgtttcacagcaatgtgaatatgcttaacactacggaacttgtatatgtaaaattggttaaATATTATGTTTTTATCATATAAATAAAATGCATAAAAAAAAGAGAAAGAAACCTGAGCAATAGTCCTGGACTTTACTCTTTGCCTCATATAAACTTACTACCACTATGTcaataaaaaataaacagagctaaaaaaaaatgggcaaaggactggaacagacatttctccagaagagatatacaaatggccaacagataaataaaaagatgttcaacatcattagtccttagggaaatgcaaatcaaaaaccataatgaggtatcactttacactcactaggatggctataatttaaaaagaaaataacaaaataagttttgaccaggatatgaagaaactgtactcctcatacattgctggtggaaatgtaatatggttcagctgctgtgaaaatagtttggaattcttccaggagttaaacacagaattaccacatgacccagcaattccactcccaggtatatacccaaaggaattgaaaacaggtactgaaacatgccagcactattcacaatagtcaaaagttggaaacagccaaaagtccatcaatggatgaatggataaaaatattgtggtctatgcatagtggaaaattattcaattataaaaaagaatgaagtattgatatatgctatacaacatgacgaatttgaaaaaaatattagaagccaggtcaggttacatattgattaattctatttacctgaaatatatagaataaataaatccatagagacaacacagactacttgataggtgaggtgaatggggagcaattgctgcaataggtataggatttcctttggggataatgaaaatgttttggaactagatagaggtggtgtttgcacaatattgtgaatgtactaaatgccatttaattgtccacttaaagtgattTTGTTATTTTGCTACAACAACAAAAAAATTATATATGCAAGTTTTAAATgcatttcaccaacattctatatattaacaacaggtgatcaaacaggattagtagaatctttcaactttgaatgtgaagcagacctaagctgaaaatattatgatactaaagcaaatcaaagggatgtaatAACCTTGGAAAGCAAAAATTATTTTTATTTACTTGAAATGCAGTTCTCTTGAAAAAAAATGTAATAGGCAATAAATGTTCTTTCTTTCCAAGTATTGATTGAGAGTGTGGGGTACAGTTAGATCACACGAGTTCGCATTCTCCCAGGCATGTTCTGGAAGACTATCAAATGCATTGTATCTTTCCCACATCTTTCTGTACTAAGAGTTGCATCATTGTTGATTCAAAATTTACCACATACATCCACTTTTCCCTCTGCTGGCTGCCTCCATACTACCACACTCTAATGGACTAAATCTACCAGAGCTGGGGTTATAACCATTTAAAAATATTTACTAAGCATTTATGTATTATGTGCCATACACTTTCCTGGGTTCTGAGTATATCATAGTAAAGACTTAATTTTTCATCTAGTAGAAAGACCATGAACAACCTATTTATATATCATGATTAAGTACTGTAAAATAGTGCTATACCAGAGAATGAGAGGGATATTATTTGAGGCAGTGTTATCAGGCAAGGTTTCTCTTAGGAGGGATATCTAACCCGAAAGACTTGCATGGCATTAACCAACGGCAGTAGTGAGTTTGGGACTGTGTAAAGCTTTTTTTAAGGCCAGTACACTTTTCAAGCTAGCGTTACAGGGCGGCAAAGGATATTATTCTGTGACAGAACAACAATGACTACAGACCGGTTACAGGACAAGCGATGCTCGAGTATTTAAGGGAAAAACAAATAAGGTTTTCGGGGTGTCTTGCTATGACTGCCAGAATTAGGGCGGGCAAGACACGTTCCCGAAATGAAAATCTTCCAACGGAGTCTGAACTACAGGAAAGCCTAAGCGAGCTGAACTCCGGTCTCAGTCTCTTCCTTGGGTAGTATCAAAGGTAGAGTGTCAGACATCGAACTGGGGCTCCGCCCTAGCCCACGGGAACGTGGAAAACCTCAGGCAGGGACGAGTCTAACCTTCCGAGGTGAACCTGTGCCACAGACGGTGCTGACTCGCGGATTACCAGAACCCTCCACCTGACTGCTGGTTATCTCCACCCCCGGAAGTGCCTCCAACCCGATTACTTCCGCTATGCCAGGATTTTTTTTTTTTTGTCTCGCGAGAACTGAAAGTGTCTATGTGATCTCTAAGCGGAAGTCAGGCCTCTTTTTCGTGGCGCCTCGGAGGCGGTCGGCTGCTTCAGGATGAAGGTACGAAATGGTAGCGGGTGTTGAACTAGGCTTGGGGTGCGTCCATCGTACCCCAAAACACGGTGTTGCCGCAGTGGTAGCTCGCCAAAGCCTTGGCTCTAGGTAGAGAAGGGTCTGCGGTAGGAGGAAGCTCGCCCTTAATAGGGCCGGAGCTTCTTGGGAAAGTGGATGGCGAGAGATTGCTGCTGGAGCCGGGCCATGTCGGGAGGCCATGGTGGCGTCCGGACAGATGCGGCCATACTGGCCAGTTGGCGTCCCACGGGTTGGGTTCCTTACTCCGAGAGAGGGTGAATGGCAGCAGATCACCCTTCGCCCCAGCTCCTCCGCAGGGCTTGGAAAAATGTGTCCTATTTTTAGTGCGGTGTTTCTTGCGCGTAATTATGCACACGTGCTTCAGTGAATAAAATCAATATTTCAAGTTTTCTGATTGTATGGAGGTGACATGAAAGGATTTTTGCAATGGAATGCTTTTGTAGGTGGTTCTGCAGTTTTCGTAAAGCTCTTTTTTCCCCCCTGCCCCGCTTAAATTCTTAGCTGAACATCTCTTTCCCAGCCACTGGCTGCCAGAAGCTCATTGAAGTGGACGATGAACGAAAACTTCGTACATTTTATGAGAAGCGTATGGCCACAGAAGTTGCTGCTGACGCTCTGGGTGAAGAATGGAAGGGTTATGTGGTTCGAATCAGTGGTGGAAACGACAAGCAAGGTTTCCCCATGAAGCAGGGTGTCTTGACCCATGGCCGTGTCCGCCTGCTACTGAGTAAGGGGCATTCCTGTTACAGGCCAAGGAGGACTGGAGAAAGAAAGCGCAAATCTGTTCGGGGTTGCATTGTGGATGCCAATCTGAGTGTTCTCAACTTGGTCATTGTGAAAAAAGGGGAGAAAGATATTCCTGGTCTCACTGATACTACTGTGCCTCGTCGCCTGGGGCCCAAAAGAGCTAGCAGAATCCGCAAACTTTTCAATCTCTCTAAAGAAGATGATGTCCGCCAATACGTTGTGAGAAAGCCCCTAAACAAAGAAGGTAAGAAACCTAGGACCAAAGCACCCAAGATTCAGCGTCTTGTTACTCCACGCGTCTTGCAGCATAAACGTCGGCGTATTGCTCTGAAGAAACAGCGTACTAAGAAAAATAAGGAAGAGGCTGCAGAATATGCTAAACTTTTGGCCAAGAGAATGAAGGAGGCCAAAGAGAAACGCCAGGAACAGATTGCCAAGAGACGTAGACTTTCCTCTCTGAGAGCTTCTACCTCTAAGTCTGAGTCCAGTCAAAAATGAGATTTTGTAAGAGT

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