Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name MDH1P3
Plot displaying the genomic locations of a retrocopy (in chr14) and its respective parental gene (in chr4). Each line represents a retrocopy.
Species Microcebus murinus
Coordinates chr14:32305819-32306907  UCSC
Strand +
Parental Sequence XM_012764906.2
Parental seq. overlap 936 bp
Parental seq. overlap (%) 56.5%
Genomic Region Intergenic
Retrocopy Summary MDH1P3, located on chr14:32305819-32306907, is a retrocopy of the parental gene MDH1. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name MDH1
Full Name N/A
Also known as -
Coordinate chr4:10252556-10269294
Strand +
Gene summary N/A

Homology

Species Scientific Name Retrocopy
Human Homo sapiens MDH1P2
Chimpanzee Pan troglodytes MDH1P1
Bonobo Pan paniscus MDH1P1
Gorilla Gorilla gorilla MDH1P1
Orangutan Pongo abelii MDH1P1
Gibbon Nomascus leucogenys MDH1P1
Green monkey Chlorocebus sabaeus MDH1P1
Crab-eating macaque Macaca fascicularis MDH1P1
Rhesus Macaca mulatta MDH1P1
Baboon Papio anubis MDH1P1
Golden snub-nosed monkey Rhinopithecus roxellana MDH1P1
Marmoset Callithrix jacchus MDH1P2
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>MDH1P3
AGCATATTCACTGCCATAATGTGTTGGAAATGAGCCTGTCCCTGGTAGAGACCAGCCTATAATTCTTGTGATGTTGGATATCACCCCTATGATGCGTGTCCTGGATGTTGTCCTAATGCAGCTGCAAGATTATGCCCTTTCCCTCGTGAAAGATGTCATCCCAACAGATGAAGAAGAGGCTGCCTTCAAAGACCCGGATGTGGCCATTCTCTTGGGCTCCATGCCAAGAAGGGAAGGCGCAGAGAAGAAAGATTTCCTGAAAGCAAATGTGAAAATCATCAAAGGCCAGGGTGCAGCCTTAGAGAAATACGCCAACAAATGAGTTAGGGTTATTGTTATGGGAAACCCAGCCAACACCAACTGCCTGGCAGCCTCCAAGCTGGCTCCATCCATCCCCAAGGAGAACTTCAGTTGCTTGACTTGTTTGGATCATGACCAAGCTAAAGCTCAAATTGCTCTTAAACTTGGTGTGACTGCTGATGATGTAAAGAATGTCATTATATGGGGAAACCATTCCTTGACTCGGTACCCAGATGTCAACCATGCCAAGGCAGAATTAGAAGGAAAGCGAGTTAGTGTTTATGAAGCTCTGAAACACGACAGCTGGATTCTGGGAGAATCCATCGCGACTGTGCAGCAGTTCGAAAACTATCCAGGGCACTGTCTGCTGTGAGAGCCATCTCTGTCCCCATCTGCCATCTGGTTTGGAGCCCCAGAGGGAGAGTCTGTGTCCTCGAGCGTTTCCTCTGATGGCAACTCCTATGGTATTCCCGGTGATCTGCTCCACTGATTCCCTGCCGTAATCGAGAATAAGACCTGGAAGTTTGTTGCAAGTCTCCTAGTAATGATGTCTCAGGTGAAAGGATGAATCTTCCTGCAGAGGAActggcagaagaaaaagaaattgctttTGAATTGCTTCCCTCTGCCTGACTAGACAATCATTTTGATGTTACTAAATGCCCCAAAGCTGAGGACTCTAAACGTCATCTTTGATGCTAATACTAAATAATGATAATGCTGCGCTTAAATTAGTTGTGgaaaacaacacattttaaagattatGTGCTTCTCGGTACAGATTTGTGA
>XM_012764906.2
CGCGTGTGGGTGGTGTCGCTAAGGAGTCGGTCTCTCCTCCCTCGACTACACAGGCATTCCCTCCCGCCAATTGCAGGGTGCCATCAGGCAAGACCTTTCCTCCCGAACCTAAACCATCCGTTTGCAATCGTCCTCCAATCAGAGCAGCTCGTCCTCCGGGACTATTTTGCAATCTCCGAAGAGTGCTGGGAGAGGGACGTGAGAAGACACTCTAATCTCGGGAAGTGTAGTTCGACACTTGAAGGAAAGGCTTTAGAGATTGGGCCAGAACCAGGGCATCGTAGACTACAGTTCCCAGAGGGCGTCGCGGTCGGCAGCGGAGCCTTTTCTAGCGGTTACCTGCGTTCGCCCTCCCCGAGCCTGTTCCTCTGTAGAGGTGACCTGACTCCTGGACGTTCCTTTTGCAGGTGCTGCAATCGTCCGCGCAGTTCTCAATCATGTCTGAACCAGTCAGAGTCCTTGTGACTGGAGCAGCTGGTCAAATTGCATATTCACTGCTGTACAGTATTGGAAATGGATCTGTCTTTGGTAAAGACCAGCCTATAATTCTTGTGCTGTTGGATATTACCCCCATGATGGGTGTCCTGGATGGTGTCCTAATGGAACTGCAAGACTGTGCCCTTCCGCTCCTGAAAGATGTTATTGCAACAGATAAAGAAGAGGTTGCCTTCAAAGACCTGGATGTGGCCATTCTCGTGGGCTCCATGCCAAGAAGGGAAGGCATGGAGAGGAAAGATTTACTGAAAGCAAACGTGAAAATCTTCAAATCCCAGGGTACAGCCTTGGAAAAATATGCCAAGAAGTCAGTGAAGGTGATTGTTGTGGGTAACCCAGCCAATACCAACTGCCTGACTGCCTCCAAGTCAGCTCCATCCATCCCCAAGGAGAACTTCAGTTGCTTGACTCGTTTGGATCACAACCGAGCTAAATctcaaATTGCTCTTAAACTTGGTGTGACTGCTGATGATGTAAAGAACGTCATTATCTGGGGAAATCATTCCTCAACTCAGTATCCAGATGTCAACCATGCCAAGGTGAAGTTGCATGGAAAAGAAGTTGGTGTTTATGAAGCTCTGAAAGATGACAGCTGGCTCAAGGGAGAATTTATCTCGACCGTGCAGCAGCGTGGTGCTGCTGTCATCAAGGCTCGAAAACTATCCAGTGCAATGTCTGCTGCGAAAGCCATTGCTGACCACGTCAGAGACATCTGGTTTGGAACTCCAGAGGGAGAGTTTGTGTCCATGGGTGTTATCTCTGATGGCAACTCCTATGGTGTTCCTGATGATCTGCTCTACTCATTCCCTGTTGTAATCAAGAATAAGACCTGGAAGTTTGTTGAAGGTCTCCCAATTAATGATTTCTCACGTGAGAAGATGGATCTTACTGCAAAGGAActgacagaagaaaaagaaactgcttttgagtttctttcctcTGCCTGACTAGACAATCATTTTGATGTTACTAAATGCTTCAAAGCTGAAGAATCTAAATGTCGTCTTTGAGTCTAgtaccaaataataataatgctataCTTAAATTACTTGtgaaaaacaacacattttaagATTGTGTGCTTCTTGGTACAGATTTGTGACAGTTCATCATCATGCTATTAGTGCtgcattctaaataaatatatattcaaatgaaa

Publications

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