Retrocopy Name | H2az1P7 |
|
Species | Mus musculus | |
Coordinates | chr12:83666981-83667947 UCSC | |
Strand | - | |
Parental Sequence | NM_016750.3 | |
Parental seq. overlap | 941 bp | |
Parental seq. overlap (%) | 87.9% | |
Genomic Region |
Intragenic (Zfyve1) |
|
Retrocopy Summary | H2az1P7, located on chr12:83666981-83667947, is a retrocopy of the parental gene H2az1. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes. |
Gene Name | H2az1 |
Full Name | H2A.Z variant histone 1 |
Also known as | H2A.Z|H2A.Z1|H2a.z-1|H2afz |
Coordinate | chr3:137570248-137572683 |
Strand | + |
Gene summary | Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene encodes a replication-independent member of the histone H2A family that is distinct from other members of the family. Studies in mice have shown that this particular histone is required for embryonic development and indicate that lack of functional histone H2A leads to embryonic lethality. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2015] |
Species | Scientific Name | Retrocopy | |
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Human | Homo sapiens | Without Homology |
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Chimpanzee | Pan troglodytes | Without Homology |
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Bonobo | Pan paniscus | Without Homology |
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Gorilla | Gorilla gorilla | Without Homology |
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Orangutan | Pongo abelii | Without Homology |
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Gibbon | Nomascus leucogenys | Without Homology |
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Green monkey | Chlorocebus sabaeus | Without Homology |
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Crab-eating macaque | Macaca fascicularis | Without Homology |
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Rhesus | Macaca mulatta | Without Homology |
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Baboon | Papio anubis | Without Homology |
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Golden snub-nosed monkey | Rhinopithecus roxellana | Without Homology |
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Marmoset | Callithrix jacchus | Without Homology |
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Mouse lemur | Microcebus murinus | Without Homology |
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Rat | Rattus norvegicus | Without Homology |
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Chinese hamster | Cricetulus griseus | Without Homology |
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Rabbit | Oryctolagus cuniculus | Without Homology |
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Pig | Sus scrofa | Without Homology |
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Cow | Bos taurus | Without Homology |
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Sheep | Ovis aries | Without Homology |
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Dolphin | Tursiops truncatus | Without Homology |
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Horse | Equus caballus | Without Homology |
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Dog | Canis familiaris | Without Homology |
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Panda | Ailuropoda melanoleuca | Without Homology |
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Cat | Felis catus | Without Homology |
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Pale spear-nosed bat | Phyllostomus discolor | Without Homology |
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Velvety free-tailed bat | Molossus molossus | Without Homology |
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Greater mouse-eared bat | Myotis myotis | Without Homology |
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Kuhl's pipistrelle | Pipistrellus kuhlii | Without Homology |
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Greater horseshoe bat | Rhinolophus ferrumequinum | Without Homology |
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Egyptian rousette | Rousettus aegyptiacus | Without Homology |
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Sloth | Choloepus didactylus | Without Homology |
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Tasmanian Devil | Sarcophilus harrisii | Without Homology |
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Opossum | Monodelphis domestica | Without Homology |
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Platypus | Ornithorhynchus anatinus | Without Homology |
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Chicken | Gallus gallus | Without Homology |
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Turkey | Meleagris gallopavo | Without Homology |
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Zebra Finch | Taeniopygia guttata | Without Homology |
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Budgerigar | Melopsittacus undulatus | Without Homology |
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Painted Turtle | Chrysemys picta | Without Homology |
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Lizard | Anolis Carolinensis | Without Homology |
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Frog | Xenopus tropicalis | Without Homology |
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Zebrafish | Danio rerio | Without Homology |
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Drosophila | Drosophila melanogaster | Without Homology |
>H2az1P7 |
GCAGTTTGAATCGCGGTCCGACGGAGGAGTGGGCGCTTGGATCTCGCTGAGCGTCTGCCTGGCCTTGTCTCTTCCTCGCTCGTCGGAGCTTCAGCACGGTCCGAGATGGCTGGCGGTAAGGCTGGAAAGGACTCCGGAAAGGCCAAGACAAAGGCGGTTTCCCGCTCGCAGCGAGCCGGCTTGTAGTTCCCTTTGGGCTGTATTCCATCGACACCTGAAATCTAGGACAACCAGCCACGGACGTGTGGGCGCGACCGCCGCTGTGTACAGCGCAGCCATCCTGGAGGACCTCACCGCAGAGATACTTGAGTTGGCAGGAAATGCATCAAAAGACTTAAAGGTAAAGTGTATTACCCCTCGTCACTTGCAGCTTGCTATACGTGGAGATGAAGAATTGGATTCTCTGATCAAAGCTACCATTGCTGGTGGTTGTGTCATCCCACACATCCACAAATCGCTGATTGGGAAGAAAGGACAACAGAAGACTATTTAAGGATGCCTGCATTCCTTATTATCTCAGGACTCTAAATAATCTTAACAGCTGTCCAGTGTTGGTGATTCCAGTGGACTGTATCTCTGTGAAAAACACAATTTTGCCTTTTTGTAATTCTATTTGAGCAAGTTGGAGGCTTAATTAGCCTTCCAACCAACCAAATTTGTGCATTCGAGGCTTAACCATATTTAAGTGTTACTGTGGCTTCAAAGAAGCTATTGATTCTGAAGTAGTGGGTTTTGATTGAGTtgactgttttttaaaaactctttggaTTTTAATTGTGATGCAGAAGTTATAGTAACAAGCATTTGATTTTGTACAGACATTGTTTCCACTCTGGTGGATAAGCTCAATAAAGGTCATATCCCAAACTAGCTTTAAACTTGCTTAATAATCAAGACTTACCTTAGATCTCACTCAGCAACAAGTACATTCTCTGCTTACTAATTAAACAGTGCATCTGTAgtcatt |
>NM_016750.3 |
GTCCCGAGGGCGGGAGGCAACCATTGGTGGGCCGAACCGGCCGAGTTCCCGGATGAGGGAACATTCTGCAGTATAAAGGGCGCGAGGAAGGCGGGAGACGGCGCAGTTTGAATCGCGGTCCGACGGAGGAGTGGGCGCTGGGATCTCGCTGAGCGTCCGCCTGGCCTCGTCTCTTCCTCGCTCGTCGGAGCTTCAGCACGGTCCGAGATGGCTGGCGGTAAGGCTGGAAAGGACTCCGGAAAGGCCAAGACAAAGGCGGTTTCCCGCTCGCAGCGAGCCGGCTTGCAGTTCCCTGTGGGCCGTATTCATCGACACCTGAAATCTAGGACAACCAGCCACGGACGTGTGGGCGCGACCGCCGCTGTGTACAGCGCAGCCATCCTGGAGTACCTCACCGCAGAGGTACTTGAGTTGGCAGGAAATGCGTCAAAAGACTTAAAGGTAAAGCGTATCACCCCTCGTCACTTGCAGCTTGCTATACGTGGAGATGAAGAATTGGATTCTCTGATCAAAGCTACCATTGCTGGTGGTGGTGTCATCCCACACATCCACAAATCGCTGATCGGGAAGAAAGGACAACAGAAGACTGTTTAAGGATGCCTGGATTCCTTATTATCTCAGGACTCTAAATATTCCTAACAGCTGTCCAGTGTTGGTGATTCCAGTGGACTGTATCTCTGTGAAAAACACAATTTTGCCTTTTTGTAATTCTATTTGAGCAAGTTGGAGGCTTAATTAGCCTTCCAACCAACCAAATTTCTGCATTCGAGTCTTAACCATATTTAAGTGTTACTGTGGCTTCAAAGAAGCTATTGATTCTGAAGTAGTGGGTTTTGATTGAGTTgactgtttttaaaaaactgtttggATTTTAATTGTGATGCAGAAGTTATAGTAACAAGCATTTGGTTTTGTACAGACATTGTTTCCACTCTGGTGGATAAGCTCAATAAAGGTCATATCCCAAACTAGCTTTAAACTTGCTTAATAATCGGGACTTACCTTAGATCTCACTCAGCAACAAGTACATTCTCTGCTTACTAATTAAACAGTGCATCTGTAGTCATAA |
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