Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name Atp6v1aP1
Plot displaying the genomic locations of a retrocopy (in chr13) and its respective parental gene (in chr16). Each line represents a retrocopy.
Species Mus musculus
Coordinates chr13:78269156-78272789  UCSC
Strand +
Parental Sequence NM_007508.6
Parental seq. overlap 3094 bp
Parental seq. overlap (%) 70.5%
Genomic Region Intragenic (Fam172a)
Retrocopy Summary Atp6v1aP1, located on chr13:78269156-78272789, is a retrocopy of the parental gene Atp6v1a. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name Atp6v1a
Full Name ATPase, H+ transporting, lysosomal V1 subunit A
Also known as Atp6a1|Atp6a2|Atp6v1a1|VA68|VPP2
Coordinate chr16:43905765-43960064
Strand -
Gene summary Enables proton-transporting ATPase activity, rotational mechanism. Predicted to be involved in cellular iron ion homeostasis; cellular response to increased oxygen levels; and proton transmembrane transport. Predicted to act upstream of or within ion transport. Located in apical plasma membrane; cytosol; and microvillus. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; heart; and sensory organ. Human ortholog(s) of this gene implicated in autosomal recessive cutis laxa type IID and developmental and epileptic encephalopathy 93. Orthologous to human ATP6V1A (ATPase H+ transporting V1 subunit A). [provided by Alliance of Genome Resources, Apr 2022]

Homology

Species Scientific Name Retrocopy
Human Homo sapiens Without Homology
Chimpanzee Pan troglodytes Without Homology
Bonobo Pan paniscus Without Homology
Gorilla Gorilla gorilla Without Homology
Orangutan Pongo abelii Without Homology
Gibbon Nomascus leucogenys Without Homology
Green monkey Chlorocebus sabaeus Without Homology
Crab-eating macaque Macaca fascicularis Without Homology
Rhesus Macaca mulatta Without Homology
Baboon Papio anubis Without Homology
Golden snub-nosed monkey Rhinopithecus roxellana Without Homology
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>Atp6v1aP1
ACATTTTGAGCCTGGGCAGGTAAATTTAACACAATGGATTTCTCCAAGCTACCCAAAATCCATGATGAAGATAAAGAAAGCACATTTAGTTCTGTGCATGGAGACTCAGGGCCTATGATTACAGCCTGTGACATGGCAAGTGCTACTATGTATGAGCTGGTGATAGTGGGGCACAGCAAGCTGGTTGGAGAGATTATTCAATTGGAAGGTGACATGGCCACCATTTAGGTGTATGAAGAAACTTCTGGTGTCTCTGTTGGAGACCCTGTACTCTGCACTGGTAAAGCTCTCTCAGTAGAGCTGAGTCCTGGCATTATGGGAACCATTTTGTCAATGAGAACTCACTCATCAAACACAAAATCATGTTACCCCCATGTAACAGAGGAAGCGTGACTTACATCGCACCGCCTGAGAATTATGATGCATCTGATGTCATCCTGGAGCTTAAATTTGAAGGTGTGAAGGAGAAGTTCAGCATGGTCCAAGTATGGCCTTTTCAGTGACAGGTGCAGCCTGTCACTGAAAAGCTACCTGCCAATCATCCCTTGCTTACTGGCCAGAGAGTTCTCAATGCCCTTTGTCCGTGTGTTCAGGAAGGAACTACTGCTATTCCAGGTGCTTTTGACTGTGAAAAGACTGATTTCCCACTCTCTATCCAAGTCTACATCAGATTCAGTGAAAGAGGAAATGAGATGTCAAAAGTTCTCCAGGCCTTCCCTGAGCTCACCATGGAAGTTGATGGCAGTCAACCATGCAGAGGACAGTGCAGGTAGCCAATACCTCCAATATGCCTGTGGCTGTAAGAGAAGCCTCCATTTACACTGGAATTACACTATCAAAATATTTCTGTGACATGGGCTACCACATCAGTATGATGGCCTACTCTACCTCGAGATGGGCTGAGGCTCTAAGAGAAATCTCTGGTCTCTTAGCTGAAATGCCTGCAGGTAGTGAATACCCTGCATACCTTGATGCCCGGCTGACTTCTTTCTGTGAGCGAGCGGGCAGAGTGAAATGTCTCAGAAACCCTGAGAGAGAAGGGAGTGTCAGCATTGTAGGAGCAGTTTCTCCACCTGGGAGTGATTTTTCTGATCCAGCCAGTCACTTCTGCAACTCTTGAGTATTCTTCAAGTGTTCTGGGGCTTGGATAAAAAGTTAGCTCAACGCAAGCACTTCCCCTCTGCCAGCTGGCTCATCAGCTACATACATGCCTTGGACAAGTATTATGACAAACACTTCACAGAGTTTGTTCCTCTGAGGACCAAAGCTAAGGACATTCTGCAGGAAGAAGAGGATCTGGTGGAAATTGTGCAGCTCGTGGAAATGCTTCTTTAGCGACGATGGATAAAATCACTCTGGAGGAAGCAAAACTTATTAAAGATGACTTCCTACAAAAAAATGTGTACACTCCTTATGACAGGTTCTGTCCATTCTACAAGACAGTGGGGATGCTGTCCAACATGATTTCATTCTATGACATGGCCCACCAAGCTATGGAGACCACTGTCCAGAGCGACAGTAAGATCACATGGTCCATTATCCTGGAGCAGATGGGGGAGATTCTCTATAAACTCTCATCCATGAAATTCAAGGATCCAGTGAAAGATGGCGAGGCAAAGATGAAGGCTGACTATGCGCAGCTTCTTGAAGATATGCAGAATGCATTTTGTAACCTTGAAGACTGGAACTGTGATttcgttcttcttcttcttcggcaAGCTCATACCTATATATTTTCCTGAATTTCTCATCTCCAACCTTTTGCTTCCTTATTGTGCAGCTTTAAGACTAGTGcctatgtgtgttcttgttcattttgctgtttctttggtAGGTCTTATAAAACAAgcattcattcctttgttccagTGTTTAAAGGGACTCCCTGACCTTTATATGAAGAGGTGATGCATATGATACACATGTAACATATGCATTGTAACATATATACTGTAAACTTGTATGTAGGGTGActaccccttctctcttctccagtAAACTGTAAGCAGGACTATTCCATGTACTCTGTTGGGAATGGAAGGACTGATCTCCATACCGTGTATGGGTGCATACGAAACTACTCAGCGTTTGTAGTCAGACCACTTGCAACTTACTGTTTTGTTGAGTAACCATTttgcaggaaatatttccatttaaaaacataaaagattaATGTTCCAATTATTTATAGCTTCCCTAGTATCAATCAGGACTGTTTGTGGACACTTGGgaactattttgttttttttttaacagacatTTGCAAGGCTGAAAATAATAGATAAATCAGTTCTCTCTGAAAacgtgaaagaaagaaaaagagccaggTGGTCAAACTTAAATTGACGTcaattaaagtatattttatttaaagagaAATTTAATATCAAGGACTTTTATATACTCAATTACTaggaaatcttttcttttttaaatacaatttaaaaatcattgaaaatgggATCCACATCATAGccattcttttcctcagacttagTCAGATGAActcagagtgggggtggggtggggactagAGTCCCACAGACACACTGCAGTGCCTGCAGGCAGTCTTCCCCTGGAGAACCACTTGCTGTAGGAGTTTGGAGCCAGAGTGGCATGGTTTTCACAAGGTACATGTGTCACgtgtttgtttgccttttgacCTTCTGAAAACAGCAAGTTTACCAattgcagaaaatattttctctgtttctctttcactGGCCCAGCAAGTTTCTCAAAGGTATCAGGTCAACAGCTTCCTTCCCGTTGATAGAGATGAAAGTTGTTCTTGTATTTAACtggtaacaaaaacaaaagaagatcaatTTTTGTCTCACTGTTTCAGTGTTTAAATAATAATTCCCATATTTGCATAATAAGACTCTCTTCAGAGAGCTTGGAGAGCTAGCTCCCTGTTCACTCTCTCCAGCTGATTGTGCTGGCGCCATGCTTCCTCTTCAGGAGGGGGAAAGACTATTGGAAGATGGCTAACACTCTCAAGTACACAAGTGTAATAGCATGAAGTATTTATTTTAAGGCTTGGTATGTTGTTTAAATTATTAAGTAGTGCATTTCTTATGGTCTTTTGGGTAGACACAGTCAGTAAACACTTCAGATGTAATGTGTAAATCCTTGCTAGTGCATGTCTACACGGTGGACTGCTATTGAAGAAGGCTATTCTTCCAACTATTGAACACTGTTGACAGATATGGATTATGCAATGGCTTGTTGGGAGGTGGATTAGCGGTGCTGCTTAATTGGTTTGCTTCCAATGTGGCTTCGTATCAAGAAGCCCTGACTAGTGGAGATGAGAAAGATTTCAAAATCTGTCTGCTTATACCTACCAGCAACCTAGGCTTGTGAGCAGAACGAATGATCCCAAGAAACTACTTGAtcaagtttgtttttgttgtcctGGATTCAAGATGTGCATTCTTCCTTGATCTAAGACTGTTAATGTATGAGGCTATAGAAAGAGTCCCCAGATTTTCACTGTAACTTTCCATTTGCACACACTGTAGAGCTTCAGACTGTTCACTGATAGTGCATCTTTAGTGGGGATGTGT
>NM_007508.6
CCTCGTCTTCTGTACTGTAGTTTCTGTAACCCCcgtcattgtaaaaaaaaaaagaaaaagaaaagaaaaagaaactaacgCTTTTCTGAAGTCGCGGAACCATTCACATCCAAGGCGGTCCGCAAAGATTTAAGCCTGCGAGACGCGGCGTGACGGGCGAGGGGAAGCGGGGTGGGGCTTGAGGACACATGACTAGCTAGGACTGGCCCGCCTCCTGCAGCTGAAGACTTCCCCTCTCTCAGTGACAGAGCCTCTGGGTCCCGTCTAGGTACACTTTCTGCATTTCGAGCCCGGGCAGGTAAATTTAACACAATGGATTTCTCCAAGCTACCCAAAATCCGAGATGAGGATAAAGAAAGTACATTTGGTTATGTGCATGGAGTCTCAGGGCCTGTGGTTACAGCCTGTGACATGGCGGGCGCTGCCATGTACGAGCTGGTGAGAGTGGGGCACAGCGAGCTGGTTGGAGAAATTATTCGATTGGAAGGTGACATGGCCACCATTCAGGTGTATGAAGAAACTTCTGGTGTCTCTGTTGGAGACCCCGTACTCCGCACTGGTAAACCTCTCTCGGTCGAGCTGGGTCCCGGGATTATGGGAGCCATTTTTGATGGTATACAGAGACCTCTGTCGGATATCAGCAGTCAGACCCAAAGTATCTACATCCCCAGAGGAGTCAATGTGTCTGCTCTCAGCAGAGATATCAAATGGGAGTTTATACCCAGCAAAAACCTACGGGTTGGTAGTCATATCACTGGTGGAGACATTTATGGGATTGTCAATGAGAACTCCCTCATCAAACACAAAATCATGTTGCCCCCACGTAACAGAGGAAGCGTGACTTACATCGCGCCGCCTGGGAATTATGATGCATCCGATGTCGTCCTGGAGCTTGAGTTTGAAGGTGTGAAGGAGAAGTTCAGCATGGTCCAAGTGTGGCCTGTGCGGCAGGTGCGGCCTGTCACTGAGAAGCTGCCCGCCAATCACCCCTTGCTTACTGGCCAGAGAGTCCTCGATGCCCTTTTCCCGTGTGTTCAGGGAGGAACTACTGCTATCCCAGGCGCCTTTGGCTGTGGAAAGACTGTGATTTCCCAGTCTCTATCCAAGTACTCCAACAGTGACGTCATCATCTATGTCGGCTGCGGTGAGAGAGGCAACGAGATGTCAGAAGTTCTCCGCGACTTCCCTGAGCTCACCATGGAGGTTGATGGGAAAGTAGAGTCCATCATGAAGAGGACAGCGCTGGTAGCCAACACCTCCAACATGCCTGTGGCTGCGAGAGAGGCCTCCATCTACACTGGAATTACACTATCAGAATATTTCCGTGACATGGGCTACCACGTCAGTATGATGGCCGACTCTACCTCTAGATGGGCTGAGGCCCTCAGAGAAATCTCTGGTCGCTTAGCTGAGATGCCTGCAGaTAGTGGATACCCTGCATACCTTGGTGCCCGGCTGGCTTCTTTCTATGAGCGAGCAGGCAGAGTGAAATGTCTCGGAAACCCTGAGAGAGAAGGGAGTGTCAGCATTGTAGGAGCAGTTTCTCCACCTGGTGGTGATTTTTCTGATCCAGTCACTTCTGCAACGCTGGGTATTGTTCAGGTGTTCTGGGGCTTGGATAAGAAGTTAGCTCAGCGCAAGCACTTCCCCTCTGTCAACTGGCTCATCAGCTACAGCAAGTACATGCGTGCCCTGGACGAGTACTATGACAAGCACTTCACGGAGTTTGTTCCTCTGAGGACCAAAGCTAAGGAGATCCTGCAGGAAGAAGAGGATCTGGCAGAAATCGTGCAGCTCGTGGGAAAGGCCTCTTTAGCAGAGACGGATAAAATCACTCTGGAGGTAGCAAAACTTATTAAAGATGACTTCCTACAGCAAAATGGGTACACTCCTTATGACAGGTTCTGTCCATTCTACAAGACAGTGGGGATGCTGTCCAACATGATTTCATTCTATGACATGGCCCGCCGAGCTGTGGAGACCACTGCCCAGAGTGACAATAAGATCACATGGTCCATTATCCGGGAGCACATGGGGGAGATTCTCTATAAACTCTCCTCCATGAAATTCAAGgatcCAGTGAAAGATGGCGAGGCAAAGATCAAGGCCGACTATGCACAGCTTCTTGAAGATATGCAGAATGCATTCCGTAGCCTTGAAGACTAGAACTGTGATTTCTTCCCTCTTCCACGGCAAGCTCATACGTGTATATTTTCCTGAATTTCTCATCTCCAACCCTTAGCTTCCATATTGTGCAGCTTTGAGACTAGTGcctatgtgtgttcttgttcattttgctgtttctttggtAGGTCTTATAAAACAAACATTCCTTTGTTCCAGTGTTTGAAGGAGCTAGCTCCCTTACCTTTATCTGAAGTGGTGAATGTAGTGCATATGATATACATTGTAAGATACACATTGTAACATGATCCATACTGTAAACTTGTATGTAAGGTGACTACCCCTTCCCTCATCTCCAGTAAACTGTAAACAGGACTACTGCATGTACTCTGTTGGGAATGGAAGGCCAGAACTCCATACCGTGGATGGATGGGTACTTAGGAAACAACTCAGCATTTGTAGTCAGACCACTTGTAACTTAGTGGTTTGTTGAGTAACCATTTTGCAGGAAATACttccatttaaaaacataaaagattaATGTTCCAATTATTTGTATCAATCAGGACCATTTTTGTGGGGCACTTGGGAACTATTTGTTTTTCAAACAGACATTTGCAAGACTGAACATAATAGATAAATCAGTTACCTCTGAAAatgtgaaagaaaggaaaaaaaaaagaaccaggtgGTCAAACTTAAATTGACATCATCTTGTTAAAGCATATTTTATTTCACTAAGAGAAATTTAATATCAGAGACTTTTATATACTCAATTACTAGAAAACCTTTTTTTTAAGTacaatttaaaaatcattgaaaatgtgATCCACATCATAGccattcttttcctcagacttagTCAGACAAGCTTCTCAGAGTGGTGGGATGGGGATTAGAATACCACAGACACTCTGCAGTGCCTGCAGGCAGTCGGCCCCAGGACAACCACTGCTGTAGGAGTTTGGGGCCAGGGTGGCATGGTTTTCACAAGGTACACGTGTCAcgtgtttgtttgcctgttgaCATTCTGAAAACAGCAAGTTTACCAATTGCAGAAaatactttctgttttctctttcacaTGCTCAGAAAGCTTCTCAAAGGTATCTGGTCACAGCAGCTTCCTTCCTGTTATAGAGGTAAAAGGTGTTCTTATATTTAACtggtaacaaaagaaaaaagaaaaaagaaaagatcaattTTTGTCTTGATGTTTCAGTGTGTTTAAATAATAATTCCCATACTTGCTTAATAAGGCTCGCTTCAGAGAGCTTGGCGAGCGAGCTCCCTGTTCACTCTCTCCAGCTGATAGTGCTGTCAGTATACACTTCAGATGTAATGTGTAAATCCTTGCTGGTGCATGTCTACACAGTGGACTGCTGCTGAAGAAGGATATTCTTCCAATTATTGAACACTGTTGACAGATATGGATTATGCAATGGCTTGTTGGGAGGTGGATTAGTGGTGCTGCTTAATCGGTTTGCTTCCAATGTGGCTTCGTATCCAGGAGCCCTGACTAGCGGAGATGAGAAAGATTTCAAAACCTGTCTGCTTATACCTACCAGCAACCTAGGCTTGTGATCAGAATGAATGATCCCAAGAAACTACTTGAccaagtttgtttttgttgtcctGGATTCGAGATGTGTTTTCTTCCTTGCTCTAAGACTGTTGATGTATGAGTGTGAAGAGGCTACAGAAACAATGCCCAGATTTTCACTGTAACTTTCCCTTTGCCCACACTGTAGAACTTGAGATTGTTCACTGATAGTGCGTCTTTAGTAAGGATGTGTTAAAATATAGcagtctttttaaaagattatgcAGTTCTCTATTTATTGTGCTGTGCCTGGTCCTAAGTGCAGCCGGTTAAACAAGTTTCATATGTATTTTTCCAGTGTTAAATCTCATACCTATTCCCTTTGGAAACTTCCATCCTGAACAATGAATAGAAGAGGCTATATAAATTGCCTCCTTATCCTTAAGATTTCACTATCTTTATGTTAAGAGTAATGTATAATTATTAAaatctatgaaaaataaaaagtggatttaaatt

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