Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name Tuba1bP5
Plot displaying the genomic locations of a retrocopy (in chr9) and its respective parental gene (in chr15). Each line represents a retrocopy.
Species Mus musculus
Coordinates chr9:90979145-90980705  UCSC
Strand +
Parental Sequence NM_011654.2
Parental seq. overlap 1537 bp
Parental seq. overlap (%) 98.2%
Genomic Region Intragenic (2700049A03Rik)
Retrocopy Summary Tuba1bP5, located on chr9:90979145-90980705, is a retrocopy of the parental gene Tuba1b. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name Tuba1b
Full Name tubulin, alpha 1B
Also known as Tuba2
Coordinate chr15:98829310-98832271
Strand -
Gene summary Predicted to enable GTP binding activity; double-stranded RNA binding activity; and ubiquitin protein ligase binding activity. Predicted to be a structural constituent of cytoskeleton. Acts upstream of or within cellular response to interleukin-4. Located in cytoplasmic microtubule. Is expressed in several structures, including genitourinary system; hemolymphoid system gland; liver; retina layer; and stomach. Orthologous to human TUBA1B (tubulin alpha 1b). [provided by Alliance of Genome Resources, Apr 2022]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes TUBA3CP3
Bonobo Pan paniscus LOC100973193P3
Gorilla Gorilla gorilla LOC101135000P3
Gibbon Nomascus leucogenys LOC100604350P1
Crab-eating macaque Macaca fascicularis TUBA1BP2
Rhesus Macaca mulatta TUBA1BP2
Baboon Papio anubis LOC101018365P5
Golden snub-nosed monkey Rhinopithecus roxellana LOC104679722P2
Panda Ailuropoda melanoleuca LOC100475162P10
Human Homo sapiens Without Homology
Orangutan Pongo abelii Without Homology
Green monkey Chlorocebus sabaeus Without Homology
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>Tuba1bP5
CCGAGACCCGGTGTCTGCTTCTATCTCTCACCCTCGCCTTCTAACCCGTTGCTATCATGCGTGAGTGCATCTCCATCCACGTTGGCCAGGCTGGTGTCCAGATCGGCAATGCCTGCTGGGAGCTCTACTGCCTGGAACATGGCATCCAGGCTGATGGCCAGATGCCAAGTGGCAAGACCATTCGGGGAGGAGATGACTCCTTCAACACCTTCAGTGAGACAGGAGCTGGCAAGCATGTGCCCCGGGCAGTGTTCGTAGACCTGGAACCCACAGTCATCGATGAAGTTCGCACTGGCACCTACCGCCAGCTCTTCCACCCTGAGCAACTCATCACAGGCAAGGAGGATGCTGCCAATAACTATGCCCGTGGCCACTACACCATTGGCAAGGAGATCATTGACCTTGTCCTGGACACGATTCGCAAGCTGGCTGACCAGTGCATAGGTCTCCAGGGCTTCTTGGTTTTCCACAGCTTTGGCGGGGGAACTGGCTCTGGCTTCACCTCCCTGCTGATGGAGCGGCTCTCTGTGGATTACGGAAAGAAGTCCAAGCTGGAGTTCTCCATTTACCCAGCCCCCcaggtttccactgctgtggttGAGCCCTACAATTCCATCCTCACCACCCACACCACCCTGGAGCACTCTGATTGTGCCTTCATGGTAGACAATGAGGCCATCTATGACATCTGTCGTAGAAACCTCGACATTGAGCACCCAACCTACACCAACCTTAACCGCCTTATTAGCCAGATTGTGTCTTCCATCACTGCTTCCCTCAGATTTGATGGGGCCCTGAATGTTGATCTGACAGAATTCCAGACCAACCTGGTACCCTACCCTCGCATCCACTTCCCTCTGGCCACTTATGCCCCTGTCATCTCTGCTGAGAAAGCCTACCATGAGCACCTTTCTGTAGCAGAGATCACCAATGCCTGCTTTGAGCCAGCCAACCAGATGGTAAAATGTGACCCTCGCCATGGTAAATACATGGCTTGCTGCCTGCTGTACCGTGGTGATGTGATTCCCAAAGATGTCAATGCTGCCATTGCCACCATCAAGACCAAGCGCAGTATCCAGTTTGTAGACTGGTGTCCCACTGGCTTCAAGGTTGGCATTAATTACCAGCCTCCCACTGTGGTACCCGGTGGTGACCTGGCCAAGGTGCAGAGAGCTGTGTGCATGCTGAGCAACACCACAGCCATTGCTGAGGCATGGGCTCGCCTAGATCACAAGTTTGATCTGATGTATGCCAAGCGTGCCTTTGTGTACTGGTATGTGGGTGAGAGCATGGAGGAGGGTGAGTTCTCTGAGGCCCGTGAGGACATGGCTGCCCTAGAGAAGGATTATGAGGAGGTTGGTGTGGATTCTGTGGAAGgcgagggggaggaagaaggagaggaataCTAAGTCCATTCCTCGAGCCCCTGTGTCGTCAAACTGCTCCAGTATTAGTTGCAGGCACTGATGCTTCTGTGCTGTTCCCATTCTGTGATCATGTCTTCTCCATGTTGTACCTCTTAAGTTTTCCATGATGTCTCAAAGTAaaagctttaagaaaa
>NM_011654.2
CGAGACCCGGTGTCTGCTTCTATCTCTCACCCTCGCCTTCTAACCCGTTGCTATCATGCGTGAGTGCATCTCCATCCACGTTGGCCAGGCTGGTGTCCAGATCGGCAATGCCTGCTGGGAGCTCTACTGCCTGGAACATGGCATCCAGCCTGATGGCCAGATGCCAAGTGACAAGACCATTGGGGGAGGAGATGACTCCTTCAACACCTTCTTCAGTGAGACAGGAGCTGGCAAGCATGTGCCCCGGGCAGTGTTCGTAGACCTGGAACCCACGGTCATCGATGAAGTTCGCACCGGCACCTACCGCCAGCTCTTCCATCCTGAGCAGCTCATCACAGGCAAGGAGGATGCTGCCAATAACTATGCCCGTGGCCACTACACCATTGGCAAGGAGATCATTGACCTTGTCCTGGACAGGATTCGCAAGCTGGCTGACCAGTGCACAGGTCTCCAGGGCTTCTTGGTTTTCCACAGCTTTGGTGGGGGAACTGGCTCTGGCTTCACCTCCCTGCTGATGGAGCGGCTCTCTGTGGATTACGGAAAGAAGTCCAAGCTGGAGTTCTCCATTTACCCAGCCCCCcaggtttccactgctgtggttGAGCCCTACAATTCCATCCTCACCACCCACACCACCCTGGAGCACTCTGATTGTGCCTTCATGGTAGACAATGAGGCCATCTATGACATCTGTCGTAGAAACCTCGACATTGAGCGCCCAACCTACACCAACCTTAACCGCCTTATTAGCCAGATTGTGTCTTCCATCACTGCTTCCCTCAGATTTGATGGGGCCCTGAATGTTGATCTGACAGAATTCCAGACCAACCTGGTACCCTACCCTCGCATCCACTTCCCTCTGGCCACTTATGCCCCTGTCATCTCTGCTGAGAAAGCCTACCATGAGCAGCTTTCTGTAGCAGAGATCACCAATGCCTGCTTTGAGCCAGCCAACCAGATGGTGAAATGTGACCCTCGCCATGGTAAATACATGGCTTGCTGCCTGCTATACCGTGGTGATGTGGTTCCCAAAGATGTCAATGCTGCCATTGCCACCATCAAGACCAAGCGCAGCATCCAGTTTGTAGACTGGTGCCCCACTGGCTTCAAGGTTGGCATTAATTACCAGCCTCCCACTGTGGTACCCGGTGGTGACCTGGCCAAGGTGCAGAGAGCTGTGTGCATGCTGAGCAACACCACAGCCATTGCTGAGGCCTGGGCTCGCCTAGATCACAAGTTTGATCTGATGTATGCCAAGCGTGCCTTTGTGCACTGGTATGTGGGTGAGGGCATGGAGGAGGGTGAGTTCTCTGAGGCCCGTGAGGACATGGCTGCCCTAGAGAAGGATTATGAGGAGGTTGGTGTGGATTCTGTGGAAGgcgagggggaggaagaaggagaggagtaCTAAGTCCATTCCTTGAGCCCCCTGTGTCGTCAAACTGCTCCAGTATTAGTTGCAGGCACTGATGCTTCTGTGCTGTTTCCATTCTGTGATCATGTCTTCTCCATGTTGTACCTCTTAAGTTTTCCATGATGTCTCAAAGTAAAAGCTTTAAGAAAA

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