Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name Ddi2P1
Plot displaying the genomic locations of a retrocopy (in chr9) and its respective parental gene (in chr4). Each line represents a retrocopy.
Species Mus musculus
Coordinates chr9:6265252-6265665  UCSC
Strand -
Parental Sequence NM_001017966.2
Parental seq. overlap 340 bp
Parental seq. overlap (%) 9.6%
Genomic Region Intragenic (Ltbp1)
Retrocopy Summary Ddi2P1, located on chr9:6265252-6265665, is a retrocopy of the parental gene Ddi2. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name Ddi2
Full Name DNA-damage inducible protein 2
Also known as 1110056G13Rik|1700027M01Rik|9130022E05Rik
Coordinate chr4:141410874-141450730
Strand -
Gene summary Predicted to enable aspartic-type endopeptidase activity; identical protein binding activity; and ubiquitin binding activity. Predicted to be involved in several processes, including cellular response to hydroxyurea; proteolysis; and regulation of DNA stability. Predicted to be located in cytosol and nucleoplasm. Is expressed in brain. Orthologous to human DDI2 (DNA damage inducible 1 homolog 2). [provided by Alliance of Genome Resources, Apr 2022]

Homology

Species Scientific Name Retrocopy
Mouse lemur Microcebus murinus LOC105870486P1
Rat Rattus norvegicus Ddi2P1
Chinese hamster Cricetulus griseus LOC100753562_1P1
Rabbit Oryctolagus cuniculus DDI2P1
Dolphin Tursiops truncatus LOC101329993P2
Greater horseshoe bat Rhinolophus ferrumequinum DDI2P1
Sloth Choloepus didactylus LOC119527911P1
Human Homo sapiens Without Homology
Chimpanzee Pan troglodytes Without Homology
Bonobo Pan paniscus Without Homology
Gorilla Gorilla gorilla Without Homology
Orangutan Pongo abelii Without Homology
Gibbon Nomascus leucogenys Without Homology
Green monkey Chlorocebus sabaeus Without Homology
Crab-eating macaque Macaca fascicularis Without Homology
Rhesus Macaca mulatta Without Homology
Baboon Papio anubis Without Homology
Golden snub-nosed monkey Rhinopithecus roxellana Without Homology
Marmoset Callithrix jacchus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>Ddi2P1
ATAGCTATGGAAGAGGCTCCGGAGAGTTTTGGACAAGTCGCTATGCTCTATATTAACTGCAAAGTGAATGGGCATCCTTTAAAGGCTTTTGTTGACTCTGGTGCCCAGATGACTATCATGAGCCAAGCTTGTGCTGAGAGATGTAATATTATGAGACTGGTAGACCGACGGTGGGGTGGGGTTGCTAAGGGAGTAGGCACACAGAGGATTATGGGCCGCGTTCATCTGGCTCAGATTCAAATTGAAGGTGATTTCTTACAGTGCTCTTTCTCTATACTTGAAGAGCAGCCCATGGATATCCTTCTAGGGCTTGATATGCTCAGGAGGCACCAGTGTTCCATCGACCTAAAGAAAAATGTGCTGGTGATTGGCACTACCGGCTCACAGACTCACTTCCTTCCTGAAGGAGAGTTG
>NM_001017966.2
AGGCAGACGGCGTCGCAGGCGGGTGGCGGCGGCCGCGCTGGCTGCCGAGGGCGGGAGCGAGTGAGTCATTGCGCGCGTGTGAGGGAGGAAaggagcgagcgagcgagcgagcgagcagcCCGCGCCCGTCGCCCTCCCGCCGCTGCCGCCAGGTCTCCCCAGCCGCCGACTGCCTTCCGCCCAGCGCCCAGGCCGGGCCGAGTCGAGCCGGGTCGGGCCCGGGCCATGCTGCTCACCGTGTACTGTGTGCGGAGGGACCTCTCCGAGGTGACCTTTTCCCTCCAGGTCGACGCCGACTTCGAGCTGCACAACTTCCGCGCGCTGTGCGAGCTCGAGTCCGGCATCCCCGCCGCCGAGAGCCAGATTGTCTATGCAGAAAGGCCTCTCACCGACAACCACAGGTCACTGGCTTCTTACGGTTTAAAAGATGGTGATGTTGTGATTCTACGACAGAAGGAGAATGCAGACCCTCGCCCTGCAGTGCAGTTCTCAAACTTACCCCGGATTGACTTCAGTAGCATAGCTGTGCCTGGCACGTCAAACCCCCAACAGCGCCAGCTGCCCAGAACCCAGGCTCAGCACTCATCTCCTGGGGAAATGGCATCTTCTCCTCAAGGCCTAGACAACCCAGCCCTGCTCCGAGACATGCTGCTGGCCAACCCGCATGAGTTGTCCTTGCTGAAGGAGCGCAACCCACCCTTGGCGGAAGCTCTGCTCAGTGGAGATCTTGAGAAATTCTCTAGGGTCTTGGTGGAGCAGCAGCAGGACCGAGCCCGGAGAGAACAAGAACGGATTCGTCTGTTTTCTGCTGACCCCTTTGATCTCGAAGCTCAGGCAAAGATAGAAGAAGATATAAGGCAGCAGAACATCGAGGAGAACATGACGATAGCTATGGAGGAGGCCCCGGAGAGCTTCGGCCAGGTCGCCATGCTGTACATCAACTGCAGAGTGAACGGGCATCCTGTGAAAGCCTTTGTCGACTCAGGAGCCCAGATGACTATTATGAGCCAGGCCTGTGCAGAAAGGTGTAACATAATGAGACTGGTAGATCGTCGGTGGGCTGGCATTGCCAAAGGAGTAGGCACACAGAAGATTATTGGAAGGGTGCATCTAGCTCAGGTTCAGATTGAAGGCGATTTTCTGGCGTGCTCCTTCTCaattctggaagaacagcctatGGACATGCTTCTGGGTCTGGACATGCTGAAACGGCACCAGTGTTCTATTGACTTGAAGAAAAATGTTCTGGTGATTGGCACCACGGGCTCACAGACCACCTTCCTTCCTGAGGGGGAGTTACCAGAGTGTGCTCGTTTGGCATATGGAACCGGGCGAGAGGACATACGGCCAGAGGAAATTGCAGACCAAGAATTAGCAGAAGCCATTCAAAAATCAGCCGAGGATGCAGAGCGTCAGAAGCCATGatgcatgtagtgtgtgtgtgctgcagctGGAGTGGGCCCGGACCAGAGAAAAGCAGTAAAGAATCTACCTCACTGGGAATGTCATCATTGCCGACTTCAGATGGGTTTGACCATCCAGCTCCTTCAGGGCAGAGTCCTGAGGTTGGTAGCCCGACGAGTCTCGCTCGCTCTGTTTCTGCTTCCGTCTGCGCCATCAAGCCCGGTGACCCCAATAGCATTGAATCTCTAGCTATGGAGGCTACGAAGGCTTCAGCTGAATTCCAGACAAACTCTAAGAAAACAGACCCTCCTCCTCTGCAGGTTCTTCCTGACCTTGCTTCCTCAGCAGAGCAGAGTCTAGCCATGCCTTTCCATAAGTCATCAAAAGAAGCCGTTGTTGCAGGTAATCTGGAGAAATCTGTTGAGaaaggaacccagggcctcagagTGTATCTCCACACAAGACAGGACGCTAGTTTAACTCTCACAACTACTGGGATGCGGGAGCCACAGATATTTGCGGAGGAAAAGAGTTGGCATCCAGAAAATCAGACCCCAAGTCCCGTGAACGGCCTTCAGCAGCACAGAGAAACAGGGAGTGTACAGCGAGAGGCTGGACAGCAGAGTGTTCCACAGGACCAGGGCTGTCTTTGTGACGCAGAAGACCTTGAGCTTCATGAAGAAGTTGTCAGTTTGGAAGCTCTGAGGAAAGGTGAGCTACAAAGACACGCTCATCTTCCCAGTGCAGAGAAGGGTCTTCCAGCTTCAGGACTCTGTAGCTGTCCATGCTCAGAAGCCCTGATGGaagtagatacagctgaacagTCTCTGGTTGCTATGTGCAGCTCAACAGGCAGGCAGGATGCCGTCATCAAGAGCCCTAGTGTAGCACATCTCGCTTCAGATAATCCCACTATGGAAGTGGAGACATTACAGTCTAACCCGTCCTGTGAGCCTGTGGAACATTCCATCTTGACTCGGGAATTGCAGCTCCCAGAAGATAATGTTGACATGTCTACAATGGATAACAAAGATGACAATTCCTCTTCCCTTCTAAGTGGCCACGGTCAGCCCTCTGTGGAATCAGCAGAAGAATTTTGTTCATCTGTCACAGTGGCCTTGAAAGAACTCCATGAGCTTTTGGTCATTAGCTGTAAGCCAGCTTCAGAAGAGTCACCTGAGCATGTTACCTGTCAGTCAGAGATAGGAGCTGAGAGCCAACCAAGTGTTTCAGACCTTTCAGGAAGAAGGGTCCAAAGTGTGCATTTGACCCCTAGTGACCAGTACTCACAAGGCTCCTGTCACCAGGCCACCTCTGAATCAGGAAAGACAGAAATCGTAGGAACTGCCCCTTGTGCTGCGGTAGAAGATGAAGCATCCACTAGCTTTGAAGGTCTGGGTGATGGCTTGTCACCTGACCGAGAAGATGTCCGCAGATCAACAGAGTCAGCCAGGAAGAGCTGTTCTGTCGCCATAACCTCAGCTAAACTGTCTGAGCAGTTGCCCTGCACCTCAGGGGTAGAAATAGCACCTGAACTTGCAGCAAGTGAGGGTGCCCACAGTCAGCCTTCAGAGCATGTGCATAATCCAGGCCCAGACAGGCCGGAGACCAGCAGTGTCTGCCCTGGAGCTGGGTTGCCCCGTAGTGGATTGGACCAACCTCCCACACAGTCCTTGTCCACCCCCTCCGTTCTTCCACCGTTCATCTTTCCTGCTGCAGATGTTGACAGGATTCTTGGTGCCGGCTTCACTCTGCAGGAAGCGCTCGGGGCTCTGCATCGAGTTGGTGGGAATGCAGACCTTGCCCTTCTTGTTTTGTTAGCAAAGAACATTGTAGTCCCAACATAATTGTGGGAAGTGGGCTAGGCCACACGTCATTCCTTTTGAAAAAGCCCTTTTCACAcaaatatactacacacacacacacacaatgtgtagaAAATCTGCAAGCAAAATGTtgagccagattttttttttgccggCCAAAGTAATTTATGATCTTTTGTCTGAATTTGTCTATTCTACTTGTTAACATTTGGGCCTTTTAAATGTATTGGCAGTGTGTGCATACAAAGCTTTTTATTCTCATGACGATGATGTATTCTGGAATAAAGCAGATGGTTTTGTGTATAGCAT

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