Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name FblP2
Plot displaying the genomic locations of a retrocopy (in chr11) and its respective parental gene (in chr7). Each line represents a retrocopy.
Species Mus musculus
Coordinates chr11:35688347-35688871  UCSC
Strand -
Parental Sequence NM_007991.3
Parental seq. overlap 429 bp
Parental seq. overlap (%) 37%
Genomic Region Intergenic
Retrocopy Summary FblP2, located on chr11:35688347-35688871, is a retrocopy of the parental gene Fbl. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name Fbl
Full Name fibrillarin
Also known as FIB|FLRN|RNU3IP1
Coordinate chr7:27868345-27878694
Strand +
Gene summary Enables RNA binding activity. Acts upstream of or within sno(s)RNA metabolic process. Located in Cajal body and granular component. Is expressed in several structures, including central nervous system; early conceptus; neural retina; oocyte; and submandibular gland primordium. Orthologous to human FBL (fibrillarin). [provided by Alliance of Genome Resources, Apr 2022]

Homology

Species Scientific Name Retrocopy
Gibbon Nomascus leucogenys FBLP1
Baboon Papio anubis FBLP2
Golden snub-nosed monkey Rhinopithecus roxellana FBLP2
Rat Rattus norvegicus FblP6
Chinese hamster Cricetulus griseus Fbl_1P2
Dolphin Tursiops truncatus FBLP2
Horse Equus caballus FBLP1
Cat Felis catus FBLP1
Egyptian rousette Rousettus aegyptiacus FBLP1
Human Homo sapiens Without Homology
Chimpanzee Pan troglodytes Without Homology
Bonobo Pan paniscus Without Homology
Gorilla Gorilla gorilla Without Homology
Orangutan Pongo abelii Without Homology
Green monkey Chlorocebus sabaeus Without Homology
Crab-eating macaque Macaca fascicularis Without Homology
Rhesus Macaca mulatta Without Homology
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>FblP2
TGGAATCCCTTCCGCTCCAAATTGGCAGCGGCCATCCTGGGCGGCGTGGACCAGATCCACATCAAGCCCAAGTCCAAAGTGTTGTACCTGGGCGCCGCCTCCGGAACCACTGTCTCACACGTCTCCGACATCATCGGCCCCGACGGCCTGGTCTATGCGGTTGAATTCTCCCATCGCGCCGGCCGCGATCTGGTCAACGTGGCCAAGAAGCGCACCAACATCATCCCGGTGCTGGAAGATGCCCGGCACCCGCTCAAGTATCGCATGCTCATTGGCATGGTGGACGTGATCTTCGCCGATGTGGCCCAGCCAGATCAGTCGCGCATCGTGGCGCTTAACGCCCACACCTTTCTGCGCAACGGAGGCCACTTTCTCATTTCCATCAAGGCCAACTGCATCGACTCCACAGCGTCTGCCGAGGCCGTGTTTGCTTCTGAGGTGAGGAAGCTGCAACAGGAGAACTTGAAGCCACAGGAGCAGCTGACTCTGGAGCCCTACGAAAGGGACCACGCCGTCGTCGTCGGG
>NM_007991.3
CTGAGACTCGTGGAGTCGGGGACGCCGCAGGTTGCCTGAATCGCGCGACCAGAACGCAGTAATGAAGCCAGGTTTCAGCCCCCGTGGGGGTGGCTTTGGTGGCAGAGGCGGCTTTGGTGACAGAGGCGgtagaggaggtggaagaggaggccGAGGAGGCTTTGGCGGTGGACGAGGAGGCTTTGGCGGTGGAGGTCGAGGTCGAGGCGGAGGGGGTGGTGGCTTCAGGGGACGAGGAGGTGGCGGTGGCCGAGGTGGGGGCTTCCAGTCTGGGGGCAACCGGGGTCGAGGTGGTGGCCGGGGAGGCAAGAGAGGAAACCAGTCAGGGAAGAATGTGATGGTGGAGCCGCATCGTCATGAAGGTGTCTTTATCTGTCGCGGAAAGGAGGATGCCCTTGTCACAAAGAATCTGGTCCCTGGAGAGTCTGTGTATGGAGAGAAGAGAGTCTCTATTTCAGAAGGAGATGACAAAATTGAGTACAGAGCCTGGAACCCCTTCCGCTCCAAGCTGGCAGCAGCTATCCTGGGCGGCGTAGACCAGATCCACATCAAGCCAGGAGCCAAGGTGCTCTACCTTGGGGCAGCCTCAGGCACCACCGTCTCCCACGTCTCTGATATTGTCGGCCCGGATGGTCTGGTCTACGCAGTTGAGTTCTCCCACCGCTCTGGCCGTGACCTCATCAACTTGGCCAAGAAGAGGACTAACATTATTCCTGTAATTGAAGATGCTCGACACCCACACAAATACCGCATGCTTATCGCAATGGTGGATGTCATCTTTGCCGATGTGGCCCAGCCAGACCAAACCCGAATTGTGGCCCTGAACGCCCACACCTTCCTGCGGAATGGAGGACACTTTGTGATTTCCATTAAGGCCAACTGCATTGACTCCACTGCGTCAGCAGAGGCTGTGTTTGCATCTGAAGTGAAGAAGATGCAGCAGGAGAACATGAAGCCGCAGGAGCAGCTGACGCTAGAGCCTTATGAGCGAGACCACGCCGTGGTTGTCGGTGTGTACAGGCCACCTCCCAAGGTGAAGAACTGAAACTCAGAGCTGTCTGGATTGAAGAGATGTGTGTTGTTACTGTTGCACGTGTGGCTTGTGATTTTTTGGGGGCgggggagttgttttgtttttctattaaaaGACTCATCTGTC

Publications

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