Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name ERO1AP1
Plot displaying the genomic locations of a retrocopy (in chr5) and its respective parental gene (in chr1). Each line represents a retrocopy.
Species Sus scrofa
Coordinates chr5:78549289-78549563  UCSC
Strand +
Parental Sequence NM_001137627.1
Parental seq. overlap 232 bp
Parental seq. overlap (%) 16%
Genomic Region Intragenic (Rnf212)
Retrocopy Summary ERO1AP1, located on chr5:78549289-78549563, is a retrocopy of the parental gene ERO1A. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name ERO1A
Full Name endoplasmic reticulum oxidoreductase 1 alpha
Also known as ERO1-L|ERO1L
Coordinate chr1:182268651-182318147
Strand -
Gene summary N/A

Homology

Species Scientific Name Retrocopy
Human Homo sapiens ERO1AP1
Chimpanzee Pan troglodytes ERO1AP1
Bonobo Pan paniscus ERO1AP1
Gorilla Gorilla gorilla ERO1AP1
Gibbon Nomascus leucogenys ERO1AP1
Cow Bos taurus ERO1AP1
Sheep Ovis aries ERO1AP1
Horse Equus caballus ERO1AP1
Dog Canis familiaris ERO1AP2
Cat Felis catus ERO1AP1
Pale spear-nosed bat Phyllostomus discolor ERO1AP1
Greater mouse-eared bat Myotis myotis ERO1AP1
Kuhl's pipistrelle Pipistrellus kuhlii ERO1AP1
Egyptian rousette Rousettus aegyptiacus ERO1AP1
Sloth Choloepus didactylus ERO1AP1
Orangutan Pongo abelii Without Homology
Green monkey Chlorocebus sabaeus Without Homology
Crab-eating macaque Macaca fascicularis Without Homology
Rhesus Macaca mulatta Without Homology
Baboon Papio anubis Without Homology
Golden snub-nosed monkey Rhinopithecus roxellana Without Homology
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Dolphin Tursiops truncatus Without Homology
Panda Ailuropoda melanoleuca Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>ERO1AP1
CAGAATTATGGATTTTTGTTGGTTGGTTTAAATGTCGACTGTGGAAAATACTCTGACTCAGGGTTTGGGCACTGCTTTGAAGGTCTCATTTTCAGAGAAAGTGACAGCAAATATACCAGAAAGTTGGCCCAGTTATGAAATCCATCTAAGCAGACAAGAAAGAGTGTCACCATTTAATGCATTTGGAAGAATTTCTACAAATATGAAAGAACTGGAAAACTTCAGAAATTTGTTGCAAAATTCCATTAAAGAAATGAGTTGAAATATGCCTGTTT
>NM_001137627.1
AAGAGGTTATGGGCCACCGCTGGGGCTTCCTGATCGTCTTCCTGGGCGCCGTGGGGCTGCTGGGCTCGGGCTACGGCAGGCAGCAGCCCTCGGAAACGGCGGCGCAGAGGTGCTTCTGCCAGGTTAGTGGTTACTTGGATGATTGTACCTGTGATGTTGAAACCATTGATAGATTTAATAACTACAGACTTTTCCCAAGACTTCAAAAACTTCTGGAAAGTGACTACTTCAGGTATTACAAGGTAAACTTGAAAAGGCCATGTCCTTTCTGGAATGATATCAACCAGTGTGGAAGAAGGGACTGTGCTGTCAAGCCTTGTCAGTCGGATGAAATTCCCGATGGAATTAAATCTGCAAGCTATAAGTATTCTGAAGAAGCCAATAATCTCATTGAAGAATGTGAGCAAGCTGAACGACTTGGAGCTGTGGATGAATCACTGAGTGAGGAAACGCAGAAGGCTGTTCTTCAGTGGACCAAGCATGATGATTCCTCAGACAACTTCTGTGAAGCTGATGACATACAGTCTCCTGATGCGGAATATGTAGATTTGCTCCTTAATCCTGAGCGCTACACGGGTTACAAGGGACCAGATGCTTGGAAAATATGGAATGTCATCTATGAAGAAAACTGTTTTAAGCCACAGACAATTAAAAGACCTTTAAATCCTTTGGCTTCTGGTCAAGGGAAAAGTGAAGAGAATACCTTTTACAGTTGGCTAGAAGGTCTCTGTGTAGAAAAGAGAGCATTCTATAGACTTATATCTGGCCTCCACGCAAGCATTAATGTGCATTTGAGTGCACGGTATCTTCTACAAGATACCTGGTTGGAAAAAAAATGGGGACACAACATTACAGAATTTCAGCAGCGATTTGATGGAATTTTGACTGAAGGAGAAGGTCCAAGAAGGCTTAAGAACTTGTATTTTCTCTATTTAATAGAATTAAGGGCTTTATCTAAAGTGGTACCATTCTTCGAGCGCCCAGATTTTCAGCTCTTTACTGGAAATAAAGTTCAGGATGCAGAGAACAAAATGTTACTTCTGGACATACTTCATGAAATCAAATCATTTCCTTTGCATTTTGATGAGAATTCATTTTTTGCTGGAGATAAAAAAGAAGCGAACAAACTAAAGGAGGATTTTCGACTGCATTTTAGAAATATTTCAAGAATCATGGATTGTGTTGGTTGTTTAAAATGTCGACTATGGGGAAAGCTTCAGACTCAAGGATTGGGCACTGCCCTGAAGATCTTGTTTTCTGAGAAACTGATAGCAAACATGCCAGAAAGTGGGCCCAGTTATGAATTCCATCTAACAAGACAAGAAATAGTATCATTATTTAATGCATTTGGAAGAATTTCTACAAGTGTGAAAGAATTAGAAAACTTCAGGAACTTGTTACAAAATATTCATTAAAGAAAACAAGTTGAAATGTGCCTGTTTCTGGAC

Publications

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