Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name ARL5AP2
Plot displaying the genomic locations of a retrocopy (in chr10) and its respective parental gene (in chr2). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr10:99011778-99014127  UCSC
Coordinates (T2T) chr10:99893399-99895748  UCSC
Coordinates (hg19) chr10:100771535-100773884  UCSC
Strand -
Parental Sequence NM_012097.4
Parental seq. overlap 1563 bp
Parental seq. overlap (%) 28.6%
Genomic Region Intragenic (HPSE2)
Retrocopy Summary ARL5AP2, located on chr10:99011778-99014127, is a retrocopy of the parental gene ARL5A. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name ARL5A
Full Name ADP ribosylation factor like GTPase 5A
Also known as ARFLP5|ARL5
Coordinate chr2:151798797-151828421
Strand -
Gene summary The protein encoded by this gene belongs to the ARF family of GTP-binding proteins. With its distinctive nuclear/nucleolar localization and interaction with HP1alpha, the protein is developmentally regulated and may play a role(s) in nuclear dynamics and/or signaling cascades during embryonic development. Alternative splicing results in multiple transcript variants encoding different isoforms. This gene has multiple pseudogenes. [provided by RefSeq, Jul 2008]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes ARL5AP1
Bonobo Pan paniscus ARL5AP2
Gorilla Gorilla gorilla ARL5AP2
Orangutan Pongo abelii ARL5AP1
Gibbon Nomascus leucogenys ARL5AP1
Green monkey Chlorocebus sabaeus ARL5AP1
Crab-eating macaque Macaca fascicularis ARL5AP1
Rhesus Macaca mulatta ARL5AP1
Baboon Papio anubis ARL5AP1
Golden snub-nosed monkey Rhinopithecus roxellana ARL5AP4
Marmoset Callithrix jacchus ARL5AP4
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>ARL5AP2
GTCAAGCAGTTAAAGTGAATTTCAAAGTAAAAGTAAGGTATGTTTTCTGAACAACATTGATAATTCTTTAATTTGCAAAGTTCTTTTTTATTTTAGGACTGAGAATATAGTGTGAGATTTTTTATTTATGTAAAATTTGTTGTATCTTCTGTAATATAAATACATTGTTTGAGAATTATAAAATGCAAGCATTTTTGAATGCTTTTAAGAATTTCTTTTAAAGATTGATTGATACAATGTATTATTTGTACAAAGAAGTAACTTGACCCAAAATACTCTTTATGCTTGCTTAGAGGAGGATATTGGTGGCCAAGAATCTCTTCGTTCTTCCTGAAACACTTACTATACTAACACAGAGTCTGTATAGTTGCTGTGAACAGTACAGACAGAGAGAGGATTTCTGTAACTAGAGAACTCTATAAAATGTTAGCACATGAGGACCTAAGAAAAGCTGGGTTACTGATTTTTGCTAATAAACAAGATGTTAAAAAATGCATAACTGTAGCAGAAATCTCCCAGTTTGTGAAGCTAACATCTATTAAAGATCACCAGTGGCATATCCAGGCATGCTGTTCTCTAACTGGTGAGGGATTGTGCCAAGGACTTGAATGGTTAATGTCACGACTTAAGATTAGATTATCTCTACTGACCTCTTCTCATAGACTTTGTATAAATGAAGTGCTAAACTTTACCTGAAAGCTGCAGCAATTAAAGATTTAGATATATTTATAATCAACTGATTTAAACTTTTTCTATGAGAAGAAAAAGTAAGACCACTTATTTGAAAACAAAGATGAAGTCTCACCTTCCAATCTGCTTTCTCATTAGTTTTTTCCAAAGTAAGTTATTAAAGCTGTGAATCACATTTTTCTCATAATGAATCCTCTCAGGACATTGTGTAGCCCCTGGTAAGTACAAAGGGAGAGGAAGACATTTTGAATTTTGAGAGCTTTATTATCAGTATAACCCTCCCTAGTTGAGTGTTATTCTCTTCTTGGTCCGTTAAGTCAAAATACAAATCAGCACAGATATTCAGTTTCCAGTATTTTAAAATATGTTACATATGGGAAGTATTTTGCATAAGGTTGTATATGTATTGTGTATATACCTCAAGTTCAAGTTAATGGCTTTGATTTAAGTTCTAAAGAAAAGCAAATAACACAAATATTAATAATATCCTTAGGTATAACCATAATGAGATAAGTACTGGCATTGGTGTTAGGTGCCATTTTATACTTTCTCCCTATATTCTCTGTATTGTATTAACCAACCCTCCAAATCATTGAGCTGCTTGTTAAAAAAAAAAAGGAAAAGGAAAAAGCATGATATTGTGTATCTATTTTTTGTTGTTGACCAATCACACAGATGGAAACATAATTCAACAGAATGTGATAGCGATCAGATTCTTGGCTTAGTATTACTAATGGGCAGGATTGTACAATGAGTAATTATCAGATTATTACTTTCAATGGTTCTTATGGCATCTAAATTACTGAATAAATTTTTAATCCATTAATCAGTCTATCATAAATTGTGATTAAAATTATCAAATGAATTATCTGCATTAATTGGAAACTGTTGTGTGAAACATGTCTACTCAGAGAAGGCAGGGTGACCTGGGTTTTGGCCTCCCTCTGGTTCTCTGGAAGTGGGCCAGCAACCAGGGCGGGAGCAGCTGCAGAGGCAGAGGCTCCAGTGTGTCTCTCTCTGCCACCCCCTTAGCCTGAGCCAGGGAGGCCAGGCGGTCTGGGTGTCTGGAGGCAGGGTCCACTGCCCGAGAATGGGAATTCTCTTCACCAGGATATGGAGACTGTTCAATCACCAGGAGCACAAAAGTATCATTATTGGGCTGGATAGTGCAGGGAAAACTACCATCCTTTAACAGTTTTCTGTGAATGAAGTTGTACATACATCTCCTACAATAGGAAGTAATGTAAAAGAGATAGTGATTAATAATACATGTTTCCAGCTg
>NM_012097.4
GCAGACAACgcggcggcgatgtccgcgagccaggcgagtgccgcggcggcagcggcggggccttgcgcgcggcagggcggcCTGGGCTTCGGCCTCCCTCCGGTTCCCTGGAAGCGGGCCCGCGACCAGCGCGGGAGCAGCAGCAGAGGCGGAGGCTCCAGCGCGTCTCTCTCCTCCCCCTCAGCCTGAGCCGGGGGAAGCCAGGCGGCCCGGGTGTCTGGAGGGGGGGGGTCCGCTGCCCGAGAATGGGAATTCTCTTCACTAGAATATGGAGACTGTTCAATCACCAGGAGCACAAAGTTATCATTGTTGGGCTGGATAATGCAGGGAAAACTACCATTCTTTACCAATTTTCTATGAATGAAGTTGTACATACATCTCCTACAATAGGAAGTAATGTAGAAGAGATAGTGATTAATAATACACGTTTCCTAATGTGGGATATTGGTGGCCAAGAATCTCTTCGTTCTTCCTGGAACACTTACTATACTAACACAGAGTTTGTAATAGTTGTTGTGGACAGTACAGACAGAGAGAGGATTTCTGTAACTAGAGAAGAACTCTATAAAATGTTAGCGCATGAGGACCTAAGAAAAGCTGGATTGCTGATTTTTGCTAATAAACAAGATGTTAAAGAATGCATGACTGTAGCAGAAATCTCCCAGTTTTTGAAGCTAACTTCTATTAAAGATCACCAGTGGCATATCCAGGCATGCTGTGCTCTAACTGGCGAGGGATTGTGCCAAGGACTTGAATGGATGATGTCACGACTTAAGATTAGATGATCTCTACTGACCTCTTCTCATAGATTTTGTATAAATGAAGTGCTGGACTTTACCTGAAAGCTGCAAAAATTAATGGTTTAGATATATTTATAATAAACTGATTTAAACTTTTTCTATAAGAAGAAAAATTAAGACCACTTATTTGAAAACAAAGATGAAGTCTCACCTTCCAGTTTGCTTTCTCATTAGTTTTTTCCAAAGTAAGTTATTGAAGCTGTGATTGACATTTTTCTCATAATGAATCCTCTCAGGACATTGTGTAGCCTATGGTAAGTACAAAGGGAGAGGAAGACATTTTGAATTTTAAGAGCTTTATTATCAGTTTAACCCTCCCTAGTTGAATGTTATTTTCTTCTTGTTCCATTAAGTCAGAATACAAATCAGCACAGATATTCGAATGTTTCCAATATTTTAAAATGTAATGTTACTTATGAAAAGTATTTTGCTTAAGGTTGTGTGTGTATTGTGTATATACCTCAAGTTCAAGTTAATGGCATTGATTTATGTTCCAGACAAAAATAACACAAATAATAATATCCTTCGTTATAACCACAATGAGATAAGTATTGGCATTAGTGTTCAGTGCCATTTTATACTTTCTCTCTGTGTTCTCTGTATTGTACTAACCAACCTCCCAAATCGCTGAGCTGCTTGTTTaaaaaaaaaaaaaaggaaaaggaaaaaGCATGACATTGTGTATCGATTTTTTGTTGTTGACCAAAATCACACACATGGAAACATGTAATTCAACAGAGTGGGAAAGCTAGCAGATTCTTGGCTTAGTATTACTAATAGGCAGGATTGTACAATGAGCAACTATCAGATTATTCCTTTCAGTGGTTCTTATGGCATCTAAATTACTGAATAAATTATTAATCCATTAATCAGTGAATCAAATTATGATTACAATTATCAAATGAATGCTCAGCATTAATTGAAAACTGTTTTGTGAAACATGTCTACCCAGAAAAGTAGCATTCTATAAATACTATTAAACAACTTAGCTATATTATTTTTAAGTATTAAATTATATGTCAAGCAGTTAAAGTGAATTTCAGAGTAAAAGTAAGGCATGTTTCTGAGCAACATTGATAATTTCTTAATTTGCAAATTTCTTCTTATTTTGGTACTTGGAATATAGTGTGAGATTTTTTATTTCTAAATTTTGTTGTATCTTCTATTACATAAATGCATTGACAATTATAAAATGCAAGTGTTTTTTGAATGATTTTAAGAATTTGGCTTAAAAATTGATTGATACAACGTATTATTTGTACTAAGAAGTAACTTGACCCAAAACACCTTTTATGTTTGCTTAGGGTATATTTTTTCAGTGTCTGAAAGTCAAAGGTATTCCTGTCACAACTGTAAACAAACTTATCCTAAATGTGTTAAAACATATTCTTGGGTACTCTATTTATGTATCTTTCATGCCTTGAAAATCTGAAGGTTAATCCAAACTCACATGTTTTAGCATATTTGAGAAAAAAAAACTACCTTCAATATCAGCCTTTTAAATTTCATGAAGATTTTGGTGAGGAATAATAGTATATAGTTTAAGTATTGACAAAACTTTGAAAGTTTCTTTCTTTAAAATGGGAAATACTCAATATCTAAATCCAGGTCAGGCATGGGATATCAGtatttaacattggatgttttatgttttatatttataatgttcaaaatgcaagcataacatttaatatttGTCCACATGGTTTTACAAAAGTAAATCTTAAATTACTAAGCTTTTCCCATATGTTCTCGTACTTTCTCAAATCCCTATAAAGAATTACTTGTTATCTATTAAAAATCTCCTTTACCCAAATCTGTATTATGGTTTCGCCAGACAAATATTATGTGATGTAGCCCAGAAAATCCACACCTTTTGTCCTTTTTATGTTTTAATTTGAATAATCATGTGCTTAGTCCCTTGGATTACTGCCACATCAGTTTAACACGATATCAGCACATTCCCTTGTCATCATCAAGGTGTTGGCTCAGATTTATTCTTAATTGGATGTTTAAAGCATGTACTACCTTGTTACAGTTGGTTTAGTGTAGTGGATTATTGACATGACATCATGAGAAGATGTGTAATTTTATACCACATTTATAAAACATGATTTTGTTTTCTACCCTTCAAGGTAAACATTAAAAATAAGGTGGTACTTGTGTACTTGTACATAAAACCAAAATTATAGTTGGGAAAAAAATAAATTTATATATGAAAATGTCAAAATCATTTTAAAAGTATTATTTTCAAATAAAATGGAGAAGCTGGTGAAAAGTCATATTGGCAATTTTTATGTAGTTTAAGTGGAATTAAGCAGAGGGAGatgcttttgggtttttaatatgccacttctgagtgaaaacatctcgtggagtcattgtgttcagctctgagaagaACAAAGATTCATAGTTCTGTACATGTGGCTGGATTTAAATATCCTGTTTTTGATACTAATTTTGAAAGTCATGTAACTTCTTTTGATATCTGGGCAAAAGTAACCATATGCTATAAGCATTTGAATATGTTTAATTTTATCATAATAGCATCTGTAAAAGTACATCTTACACATTATATAGAGGGTTCTTGTTTGAAATTTTCAGTTCTCTTTATCTTCCCAGTACCTCTTGGTCCTCATAATGGGCAAAGGATACAACGAAGGCAGGTTGTATAGGGGTTATAGTGGGGAAGTGGATAGGGGATTCATTTTCTTATGTGACATTTTGCCTTAAGAATATAAAAGTGCTTTAGCACTGATGGCTGGCATTTTTAATATAGGCAGTGAAAGTGACTTTAGAAGCATGGGATGAAATAGAGGGAAGAAGAGTTTTTATTTTCTGGCCTTTAAAAAGTGCCTAGTAGGTCATTTGAGACCCAGAGAAATGCACAGAGCTTGAGCAAAGGCATGAAGTCCCTGACATTGTTTTCCTTTTTGTCTCAGCATATAGTATTAAGATGCCTAGAAATAGGACTCTATTGTTCCCTCTTGTATAGGCACTTTACATTTCTTGTCACTACAGCAACCACATACAGTACAGACAACCTCCAAACCTGTTTATATTAGTGTAAATAGAAAATCTATAGACAACTTTCTAGTTTTCTCTGGAGGCATTTTTGGGAATGTACGTGTAATAGGCTCTGCTTTGTATACAGGAGATAATACCACATCATCGGTTATCTCCAAACTCCAGTCTTCTCTCAACTGCCCAGTTGTATGTTGTCATCAATCACTTTTTCAAGGCTGGGTAGAGACAAGTTTCTCCTCGTAACTTTGACCTCTCCCACTCTCCAAATGTAATCTGGACCTCATTGCTTTCAAGGTCAGCTTCCCCATAGCTCAGGTATCCTTTGCTCTCCTGTATCTTCATTTACTATTAGTGAAGAGATCTCTGTCCTGGAGGTTATTCTAAACTTTCTTTGTAACTATTGTTATAGACAATGGTTTCCAAACCAGTGGTTTCTATGTAGCTTTTCTAGTTCCTTGCTATCTTCTCACCACTGGCTTGAGGTAGTGATTTGGACTTTGCTCATTAGAGAGCATTATCAGAGATGTGGAGTCCATCAGAAGACCAGCTTGCAGTGTGTATAGCATATAGATGCCAATATTAGAATTCTTTAAATTATATTTAACATTTTCATGCTTCTTAATTTAACTTCACATGTTGGGAAGTAGATTCAGAAAGATAGGAGAAATACCCAGACTCTACCACTTCCGTGAGCTACTAGTTAGGCATGGGCAGGATTAAGTTTTATGTGTATTATCTTCCCACTACCAAGAATGGTTATGTTTCACAGAATACCAGTTCAGTTTGATTTGGAAAAAGATGCCAAACCAAATTTATATGTAGTCTATAATCTAAGGGCATTCTTGAAACTATTGCCCACATCCCATTTTTTTTTTCATGTTTACTTACAAAACAGAGATAAACATTAGATGTCTAAAGGAGTTAGTAATGAAAAGCCTATCCTTAAAAAATAAACCTGTTGAAATGGGCTTTAAAGACATCGAAATAATCACTTGTCATGCATTGACTGTAAATGCAGATAGAGAAATATGTCTTTGAAGCTCCACTTACACAAAAATAAAACTTGTATATCATGCTCCCTCAAAGAATGTGCGATAGATTATTTTAAGACCATGATAATAGAGTAAAAAGGAAAGAAAGCCAGAAATTACAATTTTGGATGCTAAAAAGTAACTTTCTAGTTAACCCTAAAGTCCTGTCAGATTGTGAAGAAATGTTCCAGGATACACTTGGATTAGTTATGCAGTATTTCTTATCAATGTCTAGCCCTTGTGTATTGTTCTGAAAACTAAAGTTTAAATCTTTATGCTGTTGCTTGCTAGATATCCTGTTCTTTGGTAGAAAATTCCCATAGTCTGTACTCAAGAAGTGCCTAAAAATGGATTTGTGTTGATTTTAAGCCCATCTAATAAATTATATGTATTTTCTATGGTA

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