Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name DDX23P1
Plot displaying the genomic locations of a retrocopy (in chr12) and its respective parental gene (in chr12). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr12:52730369-52733562  UCSC
Coordinates (T2T) chr12:52694862-52698055  UCSC
Coordinates (hg19) chr12:53124153-53127346  UCSC
Strand +
Parental Sequence NM_004818.3
Parental seq. overlap 2964 bp
Parental seq. overlap (%) 91%
Genomic Region Intergenic
Retrocopy Summary DDX23P1, located on chr12:52730369-52733562, is a retrocopy of the parental gene DDX23. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name DDX23
Full Name DEAD-box helicase 23
Also known as PRPF28|SNRNP100|U5-100K|U5-100KD|prp28
Coordinate chr12:48829756-48852163
Strand -
Gene summary This gene encodes a member of the DEAD box protein family. DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. The protein encoded by this gene is a component of the U5 snRNP complex; it may facilitate conformational changes in the spliceosome during nuclear pre-mRNA splicing. An alternatively spliced transcript variant has been found for this gene, but its biological validity has not been determined. [provided by RefSeq, Jul 2008]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes DDX23P1
Bonobo Pan paniscus DDX23P1
Gorilla Gorilla gorilla DDX23P1
Orangutan Pongo abelii DDX23P1
Green monkey Chlorocebus sabaeus DDX23P1
Crab-eating macaque Macaca fascicularis DDX23P1
Rhesus Macaca mulatta DDX23P1
Baboon Papio anubis DDX23P1
Golden snub-nosed monkey Rhinopithecus roxellana DDX23P1
Gibbon Nomascus leucogenys Without Homology
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>DDX23P1
GGATGGCGACAGCTCCACGACGTTGAGGCCGCATTGGGCAGTTCAGACTCCGGGTGATGACAGGAGAGTTGGCTGACAAAAAGGACCATGATGCATCACCTTCCAAGGAGGAAAGGAAGCGATCATGGACTCCTGACAGAGAGCAAGATAGAGACCAGAACTGGAAGTCTTCCCCATCTAAAGATAGGAAGCAGCATTATTCAAGGAACAGACATCGAGGAGGCAGCCATTCTTGCTTTCGTTCTCGTTCCAAATCTGCAGAAAAAGAACAACGGCACGaGGACCAATATCAAGACAATGATGGGCACAGATGGGACAAGGACCAGAAACGATCCAGTTTCTCCTGGCCGAGGAAAAGACTTTAAATCTCGGAAGGATGGAGACTCTAAGAAGGATGAAGAGGATGAACATGGTGATAAGAAGCCTAAGGCCCAGCTGTTATCCCTGGAGGAACTTCTGGCCAAGAAAAAGGCTAAGGAAGAAGCTGAGGTTAAGCCCAAGTTCCTCTCCAAAGCAGAACAAGAGGCTGAAGCTCTAAAGCAACGGCAGCAGGAGGTGGAAGAGCAGCAGAGGATGCTTGTAGAGGAGAGGAAGAAAAGGAAACAGTTCCAAGACTTGGGCAGGAAGATGTTGGAAGATTCTCAGTAATGGGAACATAGGGAACACAGGGAGAGGATGGAGCCAGAGACCAGTGGAAATGAGGATGAGAAAGGGCAGCAGAAGATACGGGAAGAGAAGGATAAGAGCAAAGAACTGCATGCCATTAAGGAGCATTACCTGGGTGGCATCAAAAAGCGGCACCAAACAAGACATCTCAATGACCGAAAGTTTGTTTTTGAGGGGGATGCATCTGAGGATACATCCATTGACTACAACCCCCTGTACAAAGAACGGCACCAGGTGCAGTTGTTAGGGCAAGGTTTCATTACAGGCATTGACCTCAAGAGCAGTCACGTTTCTGTGGAGACCTAATGGAAAAGAGGCGAACCCTGAAAGAAAAGGAGCAGGAGGAGGCAAGACTCTGCAAACTTCATAAGAAGGAAGCCAAGTGCGCTGGGATGATCGTCATTGGTCTCAGAAAAAGTTAGATGAGATGACGGACAGGGACTGGTGGCTCTTCCGTGAGGGCTACAGCATCACCACCAAAGGTGGCAAGATCCCCAATCCCATCCGATCCTGGAAAGAGTCTTCTCTGCTGCCACACATCTTGGAGGTCATTGATAAGTGTGGCTACAAGGAATCAACACCTATCCAGCGTCAGGCAATTCCCTTTGGGCTACAGAATCGTGACATCATTGGTGTGGCTGAGACTGGCCGCAGCAAGACAACAGCCTTCCTCATCCCACTGCTAGTCTAGATCACCACACTTCCCAAAATTGACAGGATCGAAGAGTCAGACTAAGGCCCTTATGCCATCATCCTGGCTCCCACCCATGAGTTGGCTCAACAGATTGAGGAAGAGACCGTCAAGTTTGGGAAGCTGCTAGATATCCAACTGTGGCTGTCATTGGTGGCATCTCCAGAGAAGACTGGGGCTTCAGGCTGCTCATGGGTTGTGAGATTGTGATCGCCACCCCTGGGCATTTGATTGATGTGCTGGAGAATCGCTACCTGGTGCTGAGCTGCTGTACCTACGTGGTTCTGGATGAGGCAGATAGGATGATTGACGTGGGCTTCGAGCCAGATGTCCAGAAGATCCTGGAGCACATGCCTGTCAGCAATCAGAAGCCAGACACGATGAGTCTGAGGACCCTGAGAAGATGCTGGCCAACTTTGAGTCAGGAAAACGTTAAGTACCATCAAAGTCATGTTCATGGCCACCAAGCCCCCAGCAGTGGAGTGTCTGGCCAGGAGCTATCTTCGGCGACCTGCTGTGGTGTACCTTGACCCCGCAGGCAAGCCCCATGAGCGTGTGGAACAGGTCTTCCTCATGTCAGAGTCAGAAAAGAGGAAAAAGCTGCTGGAAATCTTGAAGCAAGGCTTTGACCCAGCCATCACTATTTTTGTCAACCAGAAGAAGGGCTGCGACGTGTTGGCCAAATCCCTGGAGAAGATGGGGTACAATGCCTGTACACTGCACGGTGGAAAAGGCCAGGAGCAGCGAGAGTTTGCATTGTCCAACCTCAAGCCTGGGGCCAAGGATGTCTTGGTGACTACAGATGTGGCTGGTCATGGTATTGACATCCAAGATGTGTCTATGGTTGTCAACTATGATATGGCCAAAAATATTGACGATTACATCCACCGCATTGGCCGCATGGGACAAGCAGGCAAGAGTGGGGTGGCCATCACCTTCCTCACAAAAGAGGACTCTGCAGTTTTCTACGAGCTGAAGCAAGCCATCCTGGAAAGCCCAGTGTCTTCCTGTCCCCCCAAACTAGCCAATCACCCAGATGCCCAGCATAAGCCAGGCACCATCCTCACCAAGAAGCGCCGGGGAGAGACCATCTTTGCCTGACACAGCATTCTTCCTGTTCACTGAGGGCATTTCCAAAGCTGCCTCATGCCTGTTCTTCAGAACCCTCACATCCCTTTTTCCAGGTCCTCACTCTTGGGTTATGGAGGCTTAGGAAAACAATCCGACTCCCTAGCCCAGACCCTCAGGTCGGGAAGCCTGCATGTGGGGCTGCAAAAGGAGAAGACGATGCTGTAGGAGGCAGGGAGAGCAAATTACCACAGCTTTTTGGCCCAGCTCTGCCCTTCTTTGCTTTGGGATTGCACTGGGCCATAAGCTCATGCCAGGCTATGGGGGCAGCCAGTTGGCATTGCTCCCCAGACTGAACAGAAACCTGGCTGTCTGATGGGACCTCCTTTGGCACAGACTTGACTGTGTAAGTGTATAAACTGCAGCAGCATCGTTGCCCTAGATGCCCCAGGAGACCTGGCACCATGAGGATTATGGACAGTGGAATCTTACTGTCATCTGGACAGCCGTTTTCCTGTTTGGATGGTAAAGGAAGTTGAGAACCTTTAGACCTGTGCACAGCCCTGCACCAAGGAGTGCTGTGTGCTCTAGGCATCCCTTCCCCAGGGGATTTTCTAAGTAGATGGGGGGACAGGGTGAACTGACTGTGTCCTTTGTCACTGAATGAAATCTCTGTTTTCTATTCTCTGAGAAGATGTTTGTATGTTCTGAGAATAAATATATGAATATT
>NM_004818.3
ATCTCCGCGACCAGGAAACGGGAAAGATGGCGACGGCTCCGCGACGTTGAGGCCGCGTTGGGCGGTTCAGACTCAGGGTGATGGCAGGAGAGCTGGCTGACAAAAAGGACCGTGATGCATCACCTTCCAAGGAGGAAAGGAAGCGATCACGGACTCCTGACAGAGAGCGGGATAGAGACCGGGACCGGAAGTCTTCCCCATCTAAAGATAGAAAGCGGCATCGTTCAAGGGATAGACGTCGAGGAGGCAGCCGTTCTCGCTCTCGTTCCCGTTCCAAATCTGCAGAAAGAGAACGACGGCACAAAGAACGAGAACGAGATAAGGAGCGGGATCGGAATAAGAAGGACCGAGATCGAGACAAGGATGGGCACAGACGGGACAAGGACCGTAAACGATCCAGCTTATCTCCTGGTCGAGGAAAAGACTTTAAATCTCGGAAGGACAGAGACTCTAAGAAGGATGAAGAGGATGAACATGGTGATAAGAAGCCTAAGGCCCAGCCATTATCCCTGGAGGAGCTTCTGGCCAAGAAAAAGGCTGAGGAAGAAGCTGAGGCTAAGCCCAAGTTCCTCTCTAAAGCAGAACGAGAGGCTGAAGCTCTAAAGCGACGGCAGCAGGAGGTGGAAGAGCGGCAGAGGATGCTTGAAGAAGAGAGGAAGAAAAGGAAACAGTTCCAAGACTTGGGCAGGAAGATGTTGGAAGATCCTCAGGAACGGGAACGTCGGGAACGCAGGGAGAGGATGGAACGGGAGACCAATGGAAATGAGGATGAGGAAGGGCGGCAGAAGATCCGGGAAGAGAAGGATAAGAGCAAGGAACTGCATGCCATTAAGGAGCGTTACCTGGGTGGCATCAAAAAGCGGCGCCGAACGAGACATCTCAATGACCGGAAATTTGTTTTTGAGTGGGATGCATCTGAGGACACATCCATTGACTACAACCCCCTGTACAAAGAACGGCACCAGGTGCAGTTGTTAGGGCGAGGCTTCATTGCAGGCATTGACCTCAAGCAGCAGAAGCGAGAGCAGTCACGTTTCTATGGAGACCTAATGGAGAAGAGGCGAACCCTGGAAGAAAAGGAGCAGGAGGAGGCAAGACTCCGCAAACTTCGTAAGAAGGAAGCCAAGCAGCGCTGGGATGATCGTCATTGGTCTCAGAAAAAGTTAGATGAGATGACGGACAGGGACTGGCGGATCTTCCGTGAGGACTACAGCATCACCACCAAAGGTGGCAAGATCCCCAATCCCATCCGATCCTGGAAAGACTCTTCTCTGCCCCCACACATCTTGGAGGTCATTGATAAGTGTGGCTACAAGGAACCAACACCTATACAGCGTCAGGCAATTCCCATTGGGCTACAGAATCGTGACATCATTGGTGTGGCTGAGACTGGCAGTGGCAAGACAGCAGCCTTCCTCATCCCTCTGCTGGTCTGGATCACCACACTTCCCAAAATTGACAGGATCGAAGAGTCAGACCAAGGCCCTTATGCCATCATCCTGGCTCCCACCCGTGAGTTGGCTCAACAGATTGAGGAAGAGACCATCAAGTTTGGGAAACCGCTAGGTATCCGCACTGTGGCTGTCATTGGTGGCATCTCCAGAGAAGACCAGGGCTTCAGGCTGCGCATGGGTTGTGAGATTGTGATTGCTACCCCTGGGCGTTTGATTGATGTGCTGGAGAACCGCTACCTGGTGCTGAGCCGCTGTACCTATGTGGTTCTGGATGAGGCAGATAGGATGATTGACATGGGCTTTGAGCCAGATGTCCAGAAGATCCTGGAGCACATGCCTGTCAGCAACCAGAAGCCAGACACGGATGAGGCTGAGGACCCTGAGAAGATGCTGGCCAACTTTGAGTCGGGAAAACATAAGTACCGCCAAACAGTCATGTTCACGGCCACCATGCCCCCAGCGGTGGAGCGTCTGGCCAGGAGCTATCTTCGGCGACCTGCTGTGGTGTACATTGGCTCCGCAGGCAAGCCCCATGAGCGTGTGGAACAGAAGGTCTTCCTCATGTCAGAGTCAGAAAAGAGGAAAAAGCTGCTGGCAATCTTGGAGCAAGGCTTTGACCCACCCATCATTATTTTTGTCAACCAGAAGAAGGGCTGCGACGTGTTGGCCAAATCCCTGGAGAAGATGGGGTACAATGCTTGCACACTGCACGGTGGAAAAGGCCAGGAGCAGCGAGAGTTTGCGTTGTCCAACCTCAAGGCTGGGGCCAAGGATATTTTGGTGGCTACAGATGTGGCTGGTCGTGGTATTGACATCCAAGATGTGTCTATGGTTGTCAACTATGATATGGCCAAAAATATTGAAGATTACATCCACCGCATTGGCCGCACGGGACGAGCAGGCAAGAGTGGGGTGGCCATCACCTTCCTCACAAAAGAGGACTCTGCTGTGTTCTACGAGCTGAAGCAAGCTATCCTGGAAAGCCCAGTGTCTTCCTGTCCCCCCGAACTAGCCAACCACCCAGATGCCCAGCATAAGCCAGGCACCATCCTCACCAAGAAGCGCCGGGAAGAGACCATCTTTGCCTGACACAGCACTCTTCCTGTGGGCTGAGGGCATCTCCAAAGCTGCCTGATGCCTGTTTTTCAGAACCCTCACATCCCTCTTTCCAGGTCCTCACTCTTGGGATATGGGGGCTTAGGAAAACAATCCAACTCCCTAGCCCAGACCCTCAGGTCAGGAGGCCTGCGTGTGGGGCTGCAAAAGGAGAGGACGACGCTGTCGGAGGCAGGGAGAGCAAATTACCACAGCTTCTTGGCCCAGTTCTGCCCTTCTTTGCTTTGGGATTGCACTGGGCCATCAGCTCATGCCAGGCTATGGGGGCAGCCAGTTGGCATTGCTCCCCAGACTGAACAGAAACCTGGCCGCCGGATGGGACCTCCTTTGGCACAGACTTGACTGTGTAACTGCATAAACTGCAGTAGCATCATTGCCCTAGATGCCCCAGGAGACCTGGCACCATGAGGATTACAGACAGTGGAATCTTACTGTCATCTGGACAGCTGTTTTCCTGTTTGGATGGTAAAGGAAGTTGAGAGTCTTTAGACCTGTGCACAGCCCCGCACCAAGGGGTGCTGTATGCTCTAGGCATCCCCTCCCCCAGGGGATTTTCTAAGTAGATGGGGGGACACGGTGAACTGGCTGTGTCCATCTTTGTCACTGAGTGAAATCTCTGTTTTCTATTCTCTGAGAAGATAAGTTTGTATGTTCTGAGAATAAATACATGAATATTAAGACTGTTA

Publications

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