Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name OGFOD1P1
Plot displaying the genomic locations of a retrocopy (in chr13) and its respective parental gene (in chr16). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr13:49210089-49212314  UCSC
Coordinates (T2T) chr13:48431395-48433620  UCSC
Coordinates (hg19) chr13:49784225-49786450  UCSC
Strand -
Parental Sequence NM_001324363.2
Parental seq. overlap 1548 bp
Parental seq. overlap (%) 33.5%
Genomic Region Intergenic
Retrocopy Summary OGFOD1P1, located on chr13:49210089-49212314, is a retrocopy of the parental gene OGFOD1. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name OGFOD1
Full Name 2-oxoglutarate and iron dependent oxygenase domain containing 1
Also known as TPA1
Coordinate chr16:56451524-56479104
Strand +
Gene summary Enables peptidyl-proline 3-dioxygenase activity. Involved in several processes, including peptidyl-proline hydroxylation; regulation of translational termination; and stress granule assembly. Located in cytoplasmic stress granule; cytosol; and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes OGFOD1P1
Bonobo Pan paniscus OGFOD1P1
Gorilla Gorilla gorilla OGFOD1P1
Orangutan Pongo abelii OGFOD1P1
Gibbon Nomascus leucogenys OGFOD1P1
Green monkey Chlorocebus sabaeus OGFOD1P1
Crab-eating macaque Macaca fascicularis OGFOD1P1
Rhesus Macaca mulatta OGFOD1P1
Baboon Papio anubis OGFOD1P1
Golden snub-nosed monkey Rhinopithecus roxellana OGFOD1P1
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>OGFOD1P1
AACAAAAGATGATTCTATGAGAAAGCTGAGGAGAGTAAGCTTCCTGATATATTGAAGGAGTGCATGAAGTTATTTTGCTCTGAGGCACTATTCTTGCTGCTCTCCAACTTCACAGGCCTGAAGCTTCACTTCTTGGCCCCTTCGGAAGATGAGATGGATGACAAAAAAGAGGAAGCAGCAGCCTCTGCTGCTGATAGAACTGAGGAAGGGACTGGCCATAGCCCTCCTGAGCCAGAGAATAATCAGGCAGCCATCAGCATCAACGGCCAACAGAGCCATGAGCAGACAGACCGAGTCAGAGGAAAATGAAACAAAGAATGAATCAGGTGTTCCCACATGCCAAAGGGAACTGAGGCGTTGGAAGACTGGTCACCACACTTTTAATTCGTGACCATGGCAAGGCTGATTTTGCCCTAGACTTAATTCTCCACTGTGGCTGTGAAGGCTGGGGGCCAGAATATGGTGGTTTTCTTACATTGCCAAAGATGAAGACGAAGAGCTGCTAACAGTGAATCCAGAAAGCAATTCTTTGGCATTGGTCTACAGAGATAGAGACTCTGAAATTTGTCAAGCATATTAACCACTGAAGCCTGGAACAAAAGAAAACCTTCCCAAACACAACAGGTTTCTGGGACTTTTCATTTATCTATTATGAATGACAGCACTGGGCAAAGCTGAACAAAAACATGATCCTTCATCAGTACTGGGAAGTCTGGAACAGCTAAGCCTGGAGTGAAGGAGAGCTACGTGGTAGCTTGCCTGACAGTGTTCTTTAAACTGGTTGTCCTTTAATAGGACTCATGATTGTCCTCAACCTAGACCTTGAGCTTGAAGCTATGTACTTACCTCTTGAATAAAAAAAAAAAGTTGGCTTTATTTTAAACATTGAGTTCTCCTCTTTCCATATTGGCTTCTTCAGTGAATTTTTCAATGATTGGCGTGGCTCTGTACCTTGTGAGGAGATGAAACGGCCAGTGGAGCCCGGCCGGACCCGGGTGGGAAAAAAGGGAAAGAAGGAGGTGATGGCGGAATTTTCAGATGCCGTCATGGAGGAAACCTTGAAAAAGCAGGTGGTTGAGGCCTGGAGCTACGAAGCCATTGTCAGGGACATGGACCCCTTTCTTCACTGCATGATCCCAAACTTCATCCAAAGACGACTTCTTGGAAGGGCTTCAGAAGGAACTTATGAACTTAGATTTCCATGACAAGTATAATGATTTATGTAAGTTCCAGCAGTCTGATGATTTAAAGAAGAGGGCCTCACATCTCTGCTTTAAGGAAAATTCTGTTTGAAGATTTCTGGTCCTGGCTTTCTGGCATTTCTAAAATTTACTGGAACCAACCATCGATGTGTCCTGTGCTAAATATGAATTCACTGATGCCCTGCTGTGCCATGATGATGAGCTAGAAGGGCGCTGGATCGCCTTTATCCTGTACCTGGTTCTTTCCTGGGACAGGAGCCTGGAGGGTATCCTGGACCTGTACAACATTGATGAACACTTTCAACCGAAGCAGATTGTCGTCTCTTACCCCTTTATGGAACAAACTGGTTTTCTTTGAAGTATCTGCAGTGTCCTTTCACCAGGTGTCCAAAGTCCTGTCTGAAGTCACATTTGTCTATAAGTGGCTGGTTTCATGGTCCTTCACTGACTAGGCCTCCCAACTACTTTGAACCCCCTCATATCTTGGAGCCCTCACACCCCACAAGAACATGAAATTGTTTGATTGGATCAACCTTACTTATCTGGACATGGATTACCAAATTCAAACTCAAGAAGAGTTTGAAGAAAGTTCTGAAATTCTCCTAAGAAATTTCTTAAGCCTGAGAAATTTGCAAAGGTCTGTGAGGCCTTGGAGAATGGAGATGTGGAAGAGAGCAGCTGAGGTCCCCCTAAGAAAAGGTTTTTTTTTTTTTATTATCATTTTTTAAATTTTAAa
>NM_001324363.2
GTACCCTCAGGAAGGTAGCGTCTTGATCTGCGTGGCGTGGTTCTGTGCCTTGGGAAGAGATGAATGGGAAGCGGCCAGCGGAGCCCGGCCCAGCCCGGGTGGGAAAAAAGGGAAAGAAGGAGGTGATGGCGGAGTTTTCGGACGCTGTTACGGAAGAAACCTTGAAAAAGCAGGTGGCTGAGGCCTGGAGCCGCAGGACGCCGTTCAGTCACGAAGTCATTGTCATGGACATGGACCCTTTTCTTCACTGTGTGATCCCAAACTTCATCCAAAGCCAAGACTTCTTAGAAGGGCTTCAGAAGGAACTGATGAACTTGGACTTCCATGAGAAGTATAATGATTTATATAAGTTCCAGCAGTCTGATGATTTGAAGAAGAGAAGAGAGCCTCACATCTCCACTTTAAGGAAAATTCTGTTTGAAGATTTCCGGTCCTGGCTTTCTGATATTTCTAAAATTGACCTGGAATCAACCATTGACATGTCCTGTGCTAAATATGAATTCACTGATGCCCTGCTGTGCCATGATGATGAGCTGGAAGGGCGCCGGATTGCCTTCATCCTGTACCTGGTTCCTCCCTGGGACAGGAGCATGGGTGGTACCCTGGACCTGTACAGCATTGATGAACACTTTCAGCCGAAGCAGATTGTCAAGTCTCTTATCCCTTCGTGGAACAAACTGGTTTTCTTTGAAGTATCTCCTGTGTCCTTTCACCAGGTGTCTGAAGTGCTGTCTGAAGAAAAGTCACGTTTGTCTATAAGTGGCTGGTTTCATGGTCCATCATTGACTCGGCCTCCCAACTACTTTGAACCCCCCATACCTCGGAGCCCTCACATCCCACAAGATCCTGAGAAATTCACGAAAGTCTGTGAGGCCTTGGAGCATGGACATGTGGAATGGAGCAGCCGAGGTCCCCCTAACAAAAGGTTTTATGAGAAAGCTGAGGAGAGTAAGCTTCCTGAGATATTGAAGGAGTGCATGAAGTTATTTCGCTCTGAGGCACTATTCTTGCTGCTCTCCAACTTCACAGGCCTGAAGCTTCATTTCTTGGCCCCTTCGGAAGAAGATGAGATGAATGATAAAAAAGAGGCAGAAACCACTGATATCACTGAAGAAGGGACTAGCCATAGTCCTCCTGAGCCAGAGAATAATCAGATGGCCATCAGCAACAACAGCCAAcagagcaatgagcagacagacccagagccagagGAAAATGAAACAAAGAAAGAATCAAGTGTTCCCATGTGCCAAGGGGAACTGAGGCATTGGAAGACCGGTCACTACACTTTAATTCATGACCATAGCAAGGCTGAATTTGCCCTAGACTTAATTCTGTACTGTGGCTGTGAAGGCTGGGAGCCAGAATATGGCGGTTTTACTTCTTACATTGCCAAAGGTGAAGATGAAGAGCTGCTAACAGTGAATCCAGAAAGCAATTCTTTGGCATTGGTCTACAGAGACAGAGAGACTCTGAAATTTGTCAAGCATATTAACCACCGAAGCCTGGAACAAAAGAAAACCTTCCCAAACAGAACAGGTTTCTGGGACTTTTCATTCATCTATTATGAATGACAGCACTGGGCAAAGCTGAACAAAAATGTGACCCTTCGTAATTACTGGGAAGTCTGAAAGAGCTAAGCATGGAGTCAAGGAGAACTACATGGTAGCTTGCCTGACAGTGTTCTTAAAACTGGTTGTCTTTTACTAGGACTCATAATGATTGTCCTCAACCGAGACCTTGAGCTTGCAGCTAAGTACTTATCTCTTGATTAAAAAAAAAAAGTTGGCTTTTTTTTTTTTAACATTTAGTCCTTTTTCCATATTGGCTTCTTCAGTGAATTTTTAAGTTCAATTTGtttttattgaggtaaaatatttataacataaaactgaccagcttacccatttttaaatatgcaattcagtggattaagtacattctcattgttgtccagccatcaccatcatccatctccagaagttttccatcttcccaaattctgtgcccattgaacaataactccccacctccccttcccctagcaacagccataccttttgtctctatcatcaacttcactactcatatttctcatgtaagtggaatcatacagtatttgtccttttgtgactggtttcacttagcataaagtctttaagatgcatccatgttTCCAGTGTTTCGGTTTTTTTAGAAAAACTCATACGTGATTGCAgccgggcatggtggctcacgcctgtaatcccagcacttgggaggccaaggcaggcggatcacctgaggtcaggagttaaagaccagcctgacaaacatggagaaaccccatctctactaaaaatacaaaattagctgggcgtggtggcacatgcctgtaatcccagctactcaggaggctggggcaggagaattggttgaacccaggaggcggaggttgcagtgagccgagattgtgccactgcactccagcctgggcaacaagagtgaaactctgtctcaaaaaaaaaaaagaagaaaaaaaCATAAGTGATTGCAGAATTTTGTTCTTCTCATAATTTCTGGTTTAGAAAATTATGGAGCCTTACATCCTGATCATGCTGGGCCTTAGAATTCTGACACAGTGAGTCATCACATTTCCTCCCACTGCCTGTGGCCTTGTTCCACCATGACTCTCACAGTACAGTGTAGGCTTAGTGTAGTATTATTCCCTTGGAAAGGGTCTGGCCTACCATCACATGCCCCAAGAAACTTCTGGTTGGTAAAGAAGATAGGCTGCTTATTGCCATGTGTAGTCACTTCCAAGTGCCCACTGCCTTTCCATCCTGCAATTGTGGCCTGTGTATAATTAAATGATTTTAGCCTCACGTGTTGCTTCTGTTTTCCTAAATACTGTAGGGTCAACTATATAACTAATTGCTTTTTATTTTAAGAGACGGAATGCTAAAACCACATCAGAATGCCAAGAGGCTGTGCATCTTGTTAATTTTTTTCTTGAACTGTTCCAGGGAGTTACATCATAATTACCTGTGTGTGGGTATGCATGGGTGGATGAAAGATGCTGTTCTCATTCCATCCCAATAGAGTCTTCTGTTTCCTTTCTCTTTTTTACATTTATTTTTAGCTTTTGCAGTAGTGTTTAGTGTGGGTTTTACTAATTAATAGAAAAAGCACTGGGCCTTTAAACTTCTTAACTACTCTTCTCTTTCATCTCCTAAAACTTTTGAGTATTCATTCTTTTCTGAAGTTTGCATTTAAATGAAAATGACTTTCGCTTTGGCTTTTAGGTTTAGTTTCAAAAAGGtttaattctgcaccctagccagttaagaaatgttttagcaggtatgcccttgatatggatatttatatattttacacatgtagtaatattatttctataacttactgttataaaacactaatttttaaatgatgagataaaaagaaatatctagaactagttctaacattgtcttcccCTATGCATATGGTAACGAACCATTTTACACCATACTATTTTGGAGACCACAAttttttttgcgtttgagatggagtctcactctgtggcccaggctggagtacagtggcatgatatcggctcactgtgacctctgtctcctgggttcaagcaattctcctgcctcagcctcctaagtagctgggattacaggcacctgcctccatacccagctaatttttttatatttttagtagagacagggtttcaccatgttggccaggctggAGACCACAATTTTTTAACCACAGTGTAGCAACACTCAAGTGGGATTGCGAATACTGTTACTAATGGTTAATGTCACAGCTTGCCTTTTCTATATTCCAGCTGACTAaaggtcatctcactcacttgccttctgatgtgttttcatgagttgaggggaaagggTGTCAGTGGCATAACTTCAGGAAGACCCAGGGAAAAGTGCTTGGGTAGGTGAAACTGTCATGTGTGCCAAGCTTGGAAAATAGTTTGAGACTCATGGCTGTAGGCACCATCCAAGGCCAATTTTCCAATTCTGGAAAGCCAAATCTGAATCTTAGAATACCTCACAAGTGTTAAAATGTGCTTTTTAGTGTCTCCTTTATCTCAGTGTGTTTATGATCTGTCAACACATAATCATCTTTTATACACTACAAAAAGGGACTCGGGTGTCTGAGGGGAGAGAATCCCTAGGAGCCCAACTCTGATGTTGCTGTCAGTTACATCATCTACAGCAGCACCTCTTAGATTGTGAAGGATGGTGTAACTTAAAAGATTGTGTTTCTGCACTGAAGATAGATACACAGTGATAGTGAAGTTTGTTTTCCTTATAGTACTTCATTTTGCATCTTGATTGCTTTTTAGGGCCTGGGGCCAATGTCAACAACTCTTAGGTAGCAAAAGAAGAATTAGAACATGGGCATCTTTTTTATACCTCTTTCAGATAAAAGCTATGATGTTCACCTGTAAAA

Publications

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