Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name IFT20P1
Plot displaying the genomic locations of a retrocopy (in chr14) and its respective parental gene (in chr17). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr14:31018300-31018791  UCSC
Coordinates (T2T) chr14:25216131-25216622  UCSC
Coordinates (hg19) chr14:31487506-31487997  UCSC
Strand +
Parental Sequence NM_001267774.2
Parental seq. overlap 359 bp
Parental seq. overlap (%) 32.7%
Genomic Region Intragenic (STRN3)
Retrocopy Summary IFT20P1, located on chr14:31018300-31018791, is a retrocopy of the parental gene IFT20. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name IFT20
Full Name intraflagellar transport 20
Also known as -
Coordinate chr17:28328326-28335472
Strand -
Gene summary This gene encodes a intraflagellar transport protein important for intracellular transport. The encoded protein forms part of a complex involved in trafficking of proteins from the Golgi body, including recycling of immune signalling components (Finetti et al., PubMed: 19855387). This gene is part of a complex set of sense-antisense loci that may be co-regulated. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. A pseudogene of this gene is located on the long arm of chromosome 14.[provided by RefSeq, Jun 2012]

Homology

Species Scientific Name Retrocopy
Bonobo Pan paniscus IFT20P1
Gorilla Gorilla gorilla IFT20P1
Orangutan Pongo abelii IFT20P1
Gibbon Nomascus leucogenys IFT20P2
Green monkey Chlorocebus sabaeus IFT20P1
Crab-eating macaque Macaca fascicularis IFT20P2
Rhesus Macaca mulatta IFT20P2
Baboon Papio anubis IFT20P2
Golden snub-nosed monkey Rhinopithecus roxellana IFT20P2
Marmoset Callithrix jacchus IFT20P2
Chimpanzee Pan troglodytes Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>IFT20P1
GCaCAATACCTGTGACAAGCAAGCGAACTTTATTCTTTCTCGACCCTTGTTCCTATGACACACCTCCTCCTGACTGTCACCGTCACTCCTTCAGAGCAGAGCTTCTCTAGGGAACTTGGATGCGAAACAACTATGGTAAAGGACATCCTGGCTGAAGAGGGACTGCACTTTGATGAGTTGAACAAGCTGTGGGTGTTGGACTCAGAGGTTACCCAGCAGACCACAGAGCTCAAAGAAGAGTGCAAGAACTTTGCGGACAAAACTGGCCAGTTTCAGAAAACAGTTGGTGGTTTAATTGAGCTTGTTGATAAACTTGCAAAAAAAGCGTAAAATGCGAAGATGAGGGCCATGGTGCTCCGAACTTGCTCAAATCAATAGCAAAGCAGAGAGAAGCTCAACA
>NM_001267774.2
ATAGGTAAACAGGCTCTGTATCCGTGGCAGCGGCCGTGGCAGGCTGGCTGGGTACCGGCTGTCGCTGACCCAGGAGAAGCTGCCTGTCTACATCAGCCTGGGCTGCAGCGCGCTGCCGCCGCGGGGCCGGCAGctgaactatgtgctcttcagggcgggcaccgtgttgcattcatctttgtacccccagcatctagcagtgttggcatgtagtaggcactcaagaaatgtgtgttgaatgaacgaTGCCTGTGACAAGCAAGCGGACTTTATTCTTTCCTGACCCTTGCTCCTATGACACACCTCCTCCTGACTGCCACTGTCACTCCTTCAGAGCAGAACTCCTCTAGGGAACCTGGATGGGAAACAGCCATGGCCAAGGACATCCTGGGTGAAGCAGGGCTACACTTTGATGAACTGAACAAGCTGAGGGTGTTGGACCCAGAGGTTACCCAGCAGACCATAGAGCTGAAGGAAGAGTGCAAAGACTTTGTGGACAAAATTGGCCAGTTTCAGAAAATAGTTGGTGGTTTAATTGAGCTTGTTGATCAACTTGCAAAAGAAGCAGAAAATGAAAAGATGAAGGCCATCGGTGCTCGGAACTTGCTCAAATCTATAGCAAAGCAGAGAGAAGCTCAACAGCAGCAACTTCAAGCCCTAATAGCAGAAAAGAAAATGCAGCTAGAAAGGTATCGGGTTGAATATGAAGCTTTGTGTAAAGTAGAAGCAGAACAAAATGAATTTATTGACCAATTTATTTTTCAGAAATGAACTGAAAATTTCGCTTTTATAGTAGGAAGGCAAAACAAAAAAAAGCCTCTCAAAACCAAAAAAACCTCTGTAGCATTCCAGCGGCTTGACCAATGACCTATGTCACAAGAGGTGGCGTGTAAGGAATGCAGCCCCCTGAAGACAGCACTACAAGTCTGGGGGAGCCAGTTTTAACATCAGTGCACAGCTGCTGCTGGTGGCCCTGCAGTGTACGTTCTCACCTCTTATGCTTAGTTGGAACTAAGCAGTTTGTAAACTTTCATCCTTTTTTTTGTAAATTCACAAAGCTTTGGAAGGAGAAGCAATAAATTTTTGTTTTCAAATGG

Publications

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