Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

Summary

Retrocopy Name FXNP1
Plot displaying the genomic locations of a retrocopy (in chr14) and its respective parental gene (in chr9). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr14:78059599-78060278  UCSC
Coordinates (T2T) chr14:72268632-72269311  UCSC
Coordinates (hg19) chr14:78525942-78526621  UCSC
Strand -
Parental Sequence NM_000144.5
Parental seq. overlap 480 bp
Parental seq. overlap (%) 6.8%
Genomic Region Intragenic (NRXN3)
Retrocopy Summary FXNP1, located on chr14:78059599-78060278, is a retrocopy of the parental gene FXN. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name FXN
Full Name frataxin
Also known as CyaY|FA|FARR|FRDA|X25
Coordinate chr9:69035752-69079076
Strand +
Gene summary This nuclear gene encodes a mitochondrial protein which belongs to the FRATAXIN family. The protein functions in regulating mitochondrial iron transport and respiration. The expansion of intronic trinucleotide repeat GAA from 8-33 repeats to >90 repeats results in Friedreich ataxia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2016]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes FXNP3
Bonobo Pan paniscus FXNP3
Gorilla Gorilla gorilla FXNP3
Orangutan Pongo abelii FXNP3
Gibbon Nomascus leucogenys LOC115834064P2
Green monkey Chlorocebus sabaeus FXNP4
Crab-eating macaque Macaca fascicularis FXNP2
Rhesus Macaca mulatta FXNP2
Baboon Papio anubis FXNP2
Golden snub-nosed monkey Rhinopithecus roxellana FXNP1
Marmoset Callithrix jacchus FXNP3
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>FXNP1
CTTCTGAAGACAGTTGGGCAATGGGTAATGGCTCTGTGGAAAGAATGTGTGGCCTCCCACCTTGCCCCCAAGCTCTGATTTTTAATTTCTACAGATTTTTTTGGATTAATTATTTGATTTCCTCCCTCCCTCACACCATATCCCTTATCTTTTTTAATGTCTTATGCCTATGCCTGAATAAAATAACCTTTAGACTAGCGGAGGAAACGCTGGACTCCTTAGCAGAAATTTTTGAAGACCTTGCAGATGAGCCATATGCATTTGAGGACTATGATGTTTCCTTTGGGAGTGGTGTCTTAACTATTAAACTGGGTGGAGATCTAGGAACCTATTTGATCAACAGGCAGGCACCAAACAAGCAAATCTGGTTATCTTCTCCATCCAGTGGGCCCAAGAATTATGATGGGACTGGGAAAAACTGCATGTACTCCCATGACAGCGTGTCCCTCCATGAGCTGCTGGCCACAGAGCTCACTGAAGTCTTGAAAACCAAACTGGACTTGTCTTCCTTGGCCTATTCCAGAAAAGACACTTGATGCCCAGCCCAGTTTTAAAGATATTAAAAGCTAACAGACCAAGACCCCAGCTTCATTACACAGCTGAGGTCt
>NM_000144.5
AGGGCGGAGCGGGCGGCAGACCCGGAGCAGCATGTGGACTCTCGGGCGCCGCGCAGTAGCCGGCCTCCTGGCGTCacccagcccagcccaggcccagaccctcacccGGGTCCCGCGGCCGGCAGAGTTGGCCCCACTCTGCGGCCGCCGTGGCCTGCGCACCGACATCGATGCGACCTGCACGCCCCGCCGCGCAAGTTCGAACCAACGTGGCCTCAACCAGATTTGGAATGTCAAAAAGCAGAGTGTCTATTTGATGAATTTGAGGAAATCTGGAACTTTGGGCCACCCAGGCTCTCTAGATGAGACCACCTATGAAAGACTAGCAGAGGAAACGCTGGACTCTTTAGCAGAGTTTTTTGAAGACCTTGCAGACAAGCCATACACGTTTGAGGACTATGATGTCTCCTTTGGGAGTGGTGTCTTAACTGTCAAACTGGGTGGAGATCTAGGAACCTATGTGATCAACAAGCAGACGCCAAACAAGCAAATCTGGCTATCTTCTCCATCCAGTGGACCTAAGCGTTATGACTGGACTGGGAAAAACTGGGTGTACTCCCACGACGGCGTGTCCCTCCATGAGCTGCTGGCCGCAGAGCTCACTAAAGCCTTAAAAACCAAACTGGACTTGTCTTCCTTGGCCTATTCCGGAAAAGATGCTTGATGCCCAGCCCCGTTTTAAGGACATTAAAAGCTATCAGGCCAAGACCCCAGCTTCATTATGCAGCTGAGGTCtgttttttgttgttgttgttgtttattttttttattcctgcttttgAGGACAGTTGGGCTATGTGTCACAGCTCTGTAGAAAGAATGTGTTGCCTCCTACCTTGCCCCCAAGTTCTGATTTTTAATTTCTATGGAAGATTTTTTGGATTGTCGGATTTCCTCCCTCACATGATACCCCTTATCTTTTATAATGTCTTATGCCTATACCTGAATATAACAACCTTTAAAAAAGCAAAATAATAAGAAGGAAAAATTCCAGGAGGGAAAATGAATTGTCTTCACTCTTCATTCTTTGAAGGATTTACTGCAAGAAGTACATGAAGAGCAGCTGGTCAACCTGCTCACTGTTCTATCTCCAAATGAGACACATTAAAGGGTAGCCTACAAATGTTTTCAGGCTTCTTTCAAAGTGTAAGCACTTCTGAGCTCTTTAGCATTGAAGTGTCGAAAGCAACTCACACGGGAAGATCATTTCTTATTTGTGCTCTGTGACTGCCAAGGTGTGGCCTGCACTGGGTTGTCCAGGGAGACCTAGTGCTGTTTCTCCCACATATTCACATACGTGTCTGTGTGTATATATATTTTTTCAATTTAAAGGTTAGTATGGAATCAGCTGCTACAAGAATGCAAAAAATCTTCCAAAGACAAGAAAAGAGGAAAAAAAGCCGTTTTCATGAGCTGAGTGATGTAGCGTAACAAACAAAATCATGGAGCTGAGGAGGTGCCTTGTAAACATGAAGGGGCAGATAAAGGAAGGAGATACTCATGTTGATAAAGAgagccctggtcctagacatagttcagccacaaagtagttgtccctttgtggacaagtttcccaaattccctggacctctgcttccccatctgttaaatgagagaatAGAGTATGGTTGATTCCCAGCATTCAGTGGTCCTGTCAAGCAACCTAACAGGCTAGTTCTAATTCCCTATTGGGTAGATGAGGGGATGACAAAGAACAGTTTTTAAGCTATATAGGAAACATTGTTATTGGTGTTGCCCTATCGTGATTTCAGTTGAATTCATGTGAAAATAATAGCCATCCTTggcctggcgcggtggctcacacctgtaatcccagcacttttggaggccaaggtgggtggatcacctgaggtcaggagttcaagaccagcctggccaacatgatgaaaccccgtctctactaaaaatacaaaaaattagccgggcatgatggcaggtgcctgtaatcccagctacttgggaggctgaagcggaagaatcgcttgaacccagaggtggaggttgcagtgagccgagatcgtgccattgcactgtaacctgggtgactgagcaaaactctgtctcaaaataataataacaatataataataataataGCCATCCTTTATTGTACCCTTACTGGGTTAATCGTATTATACCACATTACCTCATTTTAATTTTTACTGACCTGCACTTTATACAAAGCAACAAGCCTCCAGGACATTAAAATTCATGCAAAGTTATGCTCATGTTATATTATTTTCTTACTTAAAGAAGGATTTATTAGTGgctgggcatggtggcgtgcacctgtaatcccaggtactcaggaggctgagacgggagaattgcttgaccccaggcggaggaggttacagtgagtcgagatcgtacctgagcgacagagcgagactccgtctcaaaaaaaaaaaaaaGGAGGGTTTATTAATGAGAAGTTTGTATTAATATGTAGCAAAGGCTTTTCCAATGGGTGAATAAAAACACATTCCATTAAGTCAAgctgggagcagtggcatatacctatagtcccagctgcacaggaggctgagacaggaggattgcttgaagccaggaattggagatcagcctgggcaacacagcaagatcctatctcttaaaaaaagaaaaaaaAACCTATTAATAATAAAACAGTATAAACAAAAGCTAAATAGGTAAAATATTTTTTCTGAAATAAAATTATTTTTTGAGTCTGATGGAAATGTTTAAGTGCAGTAGGCCAGTGCCAGTGAGAAAATAAATAACATCATACATGTTTGTATGTGTTTGCATCTTGCTTCTACTGAAAGTTTCAGTGcaccccacttacttagaactcggtgacatgatgtactcctttatctgggacacagcacaaaagaggtatgcagtggggctgctctgacatgaaagtggaagttaaggaatctgggctcttatggggtccttgtgggccagcccttcaggcctattttactttcattttacatatagctctaattggtttgattatctcgttcccaagGCAGTGGGAGATCCCCATTTAAGGAAAGAAAAGGggcctggcacagtggctcatgcctgtaatcccagcactttgggaggctgaggcaagtgtatcacctgaggtcaggagttcaagaccagcctggccaacatggcaaaatcccgtctctactaaaaatattaaaaaattggctgggcgtggtggttcgtgcctataatttcagctactcaggaggctgaggcaggagaatcgctgtaacctggggggtggaggttgcagtgagacgagatcatgccacttcactccagcctggccaacagagccatactccgtctcaaataaataaataaataaataaaGGGACTTCAAACACATGAACAGCAGCCAGGGGAAGAATCAAAATCATATTCTGTCAAGCAAACTGGAAAAGTACCACTGTGTGTACCAATAGCCTCCCCACCACAGACCCTGGGAGCATCGCCTCATTTATGGTGTGGTCCAGTCATCCATGTGAAGGATGAGTTTCCAGGAAAAGGTTATTAAATATTCACTGTAACATACTGGAGGAGGTGAGGAATTGCATAATACAATCTTAGAAAACttttttttcccctttctattttttgagacaggatctcactttggcactcaggctggaggacagtggtacaatcaaagctcatggcagcctcgacctccctgggcttgggcaatcctcccacaggtgtgcacctccatagctggctaatttgtgtattttttgtagagatggggtttcaccatgttgcccaggctggtctctaacacttaggctcaagtgatccacctgcctcgtcctcccaagatgctgggattacaggtgtgtgccacAGGTGTTCATCAGAAAGCTTTTTCTATTATTTTTACCTTCTTGAGTGGGTAGAACCTCAGCCACATAGAAAATAAAATGTTCTGGCATGACTTATTTAGCTCTCTGGAATTAcaaagaaggaatgaggtgtgtaaaagagaacctgggtttttgaatcacaaatttagaatttaatcgaaactctgcctcttacttgtttgtagacactgacagtggcctcatgttttttttttttttaatctataaaatggagataTCTAACATGTTGAGCCTGGGCCCACAGGCAAAGCACAATCCTGATGTGAGAAGTACTCAGTTCATGACAACTGTTGTTCTCACATGCATAGCATAATTTCATATTCACATTGGAGGACTTCTCCCAAAATATGGATGACGTTCCCTACTCAACCTTGAACTTAATCAAAATACTCAGTTTACTTAACTTCGTATTAGATTCTGATTCCCTGGAACCATTTATCGTGTGCCTTACCATGCTTATATTTTACTTGATCTTTTGCATACCTTCTAAAACTATTTTAGCCAATTTAAAATTTGACAGTTTGCATTAAATTATAGGTTTACAATATGCTTTATCCAGCTATACCTGCCCCAAATTCTGACAGATGCTTTTGCCACCTCTAAAGGAAGACCCATGTTCATAGTGATGGAGTTTGTGTGGACTAACCATGCAAGGTTGCCAAGGAAAAATCGCTTTACGCTTCCAAGGTACACACTAAGATGAAAGTAATTTTAGTCCGTGTCCAGTTGGATTCTTGGCACATAGTTATCTTCTGCTAGAACAAACTAAAACAGCTACATGCCAGCAAGGGAGAAAGGGGAAGGAGGGGCAAAGTTTTGAAATTTCATGTAAATTTATGCTGTTCAAAACGACGAGTTCATGACTTTGTGTATAGAGTAAGAAATGCCttttcttttttgagacagagtcttgctctgtcacccaggctggagtgcagtggcacgatctgggctcactacaacctccgcctcctgggttcaagcaattctctgcctcagcctcccgagtagctgggattacaggtgcctgccaccacacccggctaatttttgtatttttagtagagacggggtttcaccatcatggccaggctggtcttgaactcctgacctagtaatccacctgcctccgcctcccaaagtgctgggattacaggcgtgagccactgcacccagccAGAAATGCCTTCTAATCTTTGGTTTATCTTAATTAGCCAGGACACTTGGAGTGCATCCCGAAGTACCTGATCAGTGGCCCCTTTGGAATGTGTAAAACTCAGCTCACTTATATCCCTGCATCCGCTACAGAGACAGAATCCAAGCTCATATGTTCCATCTTCTCTGGCTGTATAGTTTAAGGAATGGAAGGCACCAGAACAGATTTATTGAAATGTTTATTAGCTGAAGATTTATTTAGACAGTTGAGGAAAACATCAGCACCCAGCAGTAAAATTGGCTCTCAAAGATTTTCTTCTCCTGTGGAAAGTCAGACCTCTGAGGCCCCATCCAGGTAGAAGTACTAGTGCAAGAAGGGCCTCTGCTGTCCACTTGTGTTTCTGTGATCTGTGGGAACATTGTTAACGCCACATCTTGACCTCAAATTGTTTAGCTCCTggccagacacggtggctcacacctgtaatcccagcactttgagaggctgaggcaggtggatcacctgaggttaggagttcgaggccagcctggtcaacatggtaaaaccccgcctctactaaaaatacaaaaattagctggccgtagtggcgcacgcctgttatcccagctactcgggaggctgaggcaggagaattgcttgaacctgggtggtggaggttgcagtgagccgagattacaccactgcactccagcctgggtgacaagagggaaactccattaaaaaaaTGTAATTCCCGTGTCTGCCATCTTAAGTGTAAAGGTGGCTAAATTATATAGAAAAATAAGACAATATCATTTCCCAATTACATTCCTTTCCTACCGCACTCTATGATGCTAGCTGAGATTTTTCCAAAAGAAAATGGCTTAAATAAAACCCTAAGAGAAAGAAAAACTTTAAATCCCTCCAAAGCTCAAAAGTAATAGAAACAGATGAGTTTGGAGTcaggatttctctgtaagattgcctaggctgtgtactgcacatctccaggtgccactgttgacagagattataactacaatgtgaagtgaatggtgccactgacagttatgcaAACCGTCCAGAGCATAGCCACCTGATCCTGCTGGGATTCCTCTTGCCAGTCCATCAGCAGTTCCCCTTGAAAGTTTCACCAAACATCCCTTAAATCTGCCCTCTCCTGCCCGTCCCCAGTGGAGGTCCTCATCATTTTTCACCTGCATTTTTGCAGGAGCTTTCTTATATCCACCTTCCTCCTTTTCTCTCAGCCCATCATCTAGCTACACAGTCTCCAGGGTAAGCTTTCAGAAAGGCAATCTCTTGTCTGTAAAACCTAAGCAGGACCAAGGCCAAGTTTCTTAGCCTGAAAAATGTGCTTTTCTGACTGAACTGTTCAGGCACTGACTCTACATATAATTATGCTTTTCTACCCCCTCACACTCAACACTTTGACTCCAGCAATCCCAAATCCCCAGATCCCTAAGTGTGCTGTGCTATTTTCACGTGGCTCTCAGACTTGGCCAGTGCTGTTTCCATTTTGGTCTTTATTCCCCACATCTCTGCCTGGGGGGTAGATTCTACCCTGAAAAATGTTCTTGGCACAGCCTTGCAAACTCCTCCTCCACTCAGCCTCTGCCTGGATGCCCTTGATTGTTCCATGTCCTCAGCATACCATGTTTGTCTTTCCCAGCACTGACCTACCAtgtgtcacccctgcttggctgtaccttccatgaggctaggactatgtgtctcctttgttgactgctgttgccctagcatcttgcacagttccttgcacacaattagagctctataaatgtcaaataaatgTGTTATAATTATATGTTTAAGATAGTTGTTCAAATAAACTCTAAATAACCCCAA

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