Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name SALL4P10
Plot displaying the genomic locations of a retrocopy (in chr16) and its respective parental gene (in chr20). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr16:20155316-20158626  UCSC
Coordinates (T2T) chr16:20086251-20089561  UCSC
Coordinates (hg19) chr16:20166638-20169948  UCSC
Strand +
Parental Sequence NM_020436.5
Parental seq. overlap 2706 bp
Parental seq. overlap (%) 51.7%
Genomic Region Intergenic
Retrocopy Summary SALL4P10, located on chr16:20155316-20158626, is a retrocopy of the parental gene SALL4. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name SALL4
Full Name spalt like transcription factor 4
Also known as DRRS|HSAL4|IVIC|ZNF797
Coordinate chr20:51782331-51802521
Strand -
Gene summary This gene encodes a zinc finger transcription factor thought to play a role in the development of abducens motor neurons. Defects in this gene are a cause of Duane-radial ray syndrome (DRRS). Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2015]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes SALL4P5
Bonobo Pan paniscus SALL4P6
Gorilla Gorilla gorilla SALL4P6
Gibbon Nomascus leucogenys SALL4P1
Green monkey Chlorocebus sabaeus SALL4P1
Crab-eating macaque Macaca fascicularis SALL4P5
Rhesus Macaca mulatta SALL4P5
Baboon Papio anubis SALL4P4
Golden snub-nosed monkey Rhinopithecus roxellana SALL4P6
Marmoset Callithrix jacchus SALL4P3
Velvety free-tailed bat Molossus molossus SALL4BP2
Greater mouse-eared bat Myotis myotis SALL4BP4
Sloth Choloepus didactylus SALL4P1
Orangutan Pongo abelii Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>SALL4P10
CAGGGCAAATAACTGTGGCTCTCTGGGAACACTGAGGCTCACACCACATCGAGGCACAAGCTGGTAAAACCCCAGCACATCAACTTGAACGAGGACCAGGGTGAGCAGCAGCCACAGCAGCTGACCCTAGCATTTGCAGATGCGGGCCCAGTGGTGCTGGTGGCCTGGGAGgCTCCAGTGAACCACCCAGGGAATCACGATGATAAAGCGGCTTCATTGGGAGGAAACACACAAATGTGAGAAATGTTGTGTGGAGTTCTTTAGCATTTGTGAGTTCTTAGAACATAAGAAAAATTGCACTAAAAATCCACCTGTTGTGTTGTCATCATGAATGACAGCGAGGGGTCAGTGTCTTCAGGAGACTTCTCCGGAGCTGTGCTGAGCCACCAGCCACTTAGTTCAAGCAGTAAGGATGGTCACAGGGAGAATGGTGGCAGCCTAGGGAGCATGAAGGAGGAGCTGGGTGTGGAGTGTGTGGTGCACTCAAAAACAGAGATGGCCTTGCCACCCACACCCCAGAAGATAAGCTATTTACTTAAAGGCAAAGTGGCCAACACTATGTGAGCCTGCAGGCAATACAGGGCACCAAAGTGGCAATGAATCAGTGGAGCTTAGATGCATTGCCAGCCTCCGTGCCCCGTAACAACAGCATCCCATGGGTCCTTGAGTAGATCCTGTGTCTGCAGCAGCAACAGCTACGGTAGATTCAGCTCACCAAGCAGGTCCTCATCCAGGTGGACATGTGGGCCTTACAGCCTTACACGCCTTCTACTCAGGTGGGGAAGGGGCCAACACCCTGAAGGCCTTGTGCAGCCACCTGCTCCAGCAGGCTTCTGCGGCTGTGGCTTTGCTCAGCCCAAAGGCTGGAAGCCAAGGTCTGTCTCTGGACACCTTGAAACAAGCCATACTACCTCACACCAACATCCTTTTCACCACCAGTTCTCCATCCCCAGGGCTGACGCCCTTTGCTGTGAAGCTGGATGGGACCAGGGTGAGCCAAATGTAATGTCCCACCTCTTGAGTGCTTTGCTTTCTCAGGCCCCGGGATTGGTGTGCTTCCAAAGTCCTTTCTCCACTGTAGCACTAGACCCATCCAAGAAAGGGAAGGGGAAGCCACTGAACATCTCCTCAGTGGATGTTAAACCCAAAGACGAGGTGATCCTCTACAAGGACAAGTGTAAGTACTGTAACAAGGTTGTTTGAGACTGATAGCTCCTTGCAGATCCACCTCCACTTCCACATGGGAAGAGAGACCCTTTGTGTGCTTTGTCTGTGATAACTGCTTCACCACCAAGGGCAACCTCAAGGTGCACATTCACCAACATCCCCAGGTGAAGGCAAACCCTCACTCTTTGCTGAGCTCTAGGACAAAATGGTGGTAGGCAGTGACATCCCCTATGCACTCTTTGTACATCAATAGATGAACTGAGTCTCTCTTTAGACAGAAAACCTGTTCTTGTAATCCCCTCTGTTGGACTACCTCAAAAGCTGTTTGGGGCCTAACCCCAAGGACCTCACAGGTGGCCCATTGCCCAGTGACCTGTAGCCCACACTTCCTGGCATGGGGCCAAACCATAATTCCCCAAGGGTTGGTGGCTTCCAAGAAAGTGGGACCCCTGAACCAGGGTCAGAGACCCTGAAATTGCAGCAGCTGGTGGAGTACATCGACATGACCACCACTGACCCCAACAAATGCCTCATTTGCCACCGAGTATTAAGCTGCTAAAGCACCCTTTAAATGCATTGCTGCATCCATACTCCAGAGACACCATTCCAATGTAAGATCTGTGGCTGAGCTTTTTCTACCAAAGGCAACCCTTAAGACACACTGGGGTTCACCAACCCAACACGTCCATAAAGGTGCAGCATCTGTGCCTTTTCTATCAGAAGAAGTTCACCGGTGCTGTGATGTTGTGGCAGCATATTCAGATGGACCTGGCCAGTCAGATTCCCAACCTTCCCCTGCCAGAGAATTCCTGTGACTTTATGGGTCCTGAGCCAATGACGGTGGATGAGAATGGCAGCACCAGTGCCATGTGCCATGATGATGTTTTTGAAAGCACCAGTGTAGATGAAGTCAGCTCCCAGAGGCCTCCAGTAGCTCCTCAAAGGTCCCTGTGCCTCTTCCCAGCATGTAGTAGGCATCATCCACACTAGAGTTCACCAAGATGGGTTCCTTAGATGCCCTGGGAAAAGTGGGTCCTGCCCCTTTTGGCCTGCAGCACTAGAGCAGCAGAGAAAACAGTTCCATGAAGAGCAATAGCTTTGACCAACGACTGGTCCTCACTAATGGGAGACCAGGAGTATCAGAGCTGAAGTCCAGACATCATGGAAGCCACATCCTTCCAGGTACTCTGCTCGGTCAATGGCCAAGCAGAAAGGATCAGTCAAAGTCTCCTGATGCTGGGGACAAAGCAGAAAGCTCTGAAAACAGCTCTACTAAGATAGAAGGTTGGAGCCATCTCCCTTCAACGTTTATCTGAGCTCAGTCAATCTATGTCACAGTTGAAGTCGCTGGCACATTTGTTGAACCCTCCACATTGTCCCTGGGGATGACCCCTTTGTCAGTGGCCTAGCCATGCCAACAGGCCAAGCAACACAGCTGCACGTGGTGTGGGAAGAACTTCTTACCCATTAGCTTTCTTCAGATTCATGAGCACACTCACACTGGAGAGAAGCCTTTTGCATGCAACATTTGTGGGTAAGCTTTTACCACCAAAGGCAACTGGAAGGTCCACTATGTGACTCAGCACGCCATGGTAGGAAGCTGGCTATCGAAAACACCATGGCTCTCTTAGGTGCAGATGGAAAGAGTCTCAAATATTTCCCAGGGAAATTCTGGCCACTTTAGTGAACATGGGCCCTGTTTTGTGGAACCAGGACACCAGCATGCTCAATGGTGGTCTGGCCAAGAAGACCAATGAGATCTCTGTGATCCAGAGTGGCGGTGTTCCTACCCTCCTGGTTTCCTTGGGAGTCAGCTTCAATATAAATAACGCCACTGTCTCCAACGCGGATGGCTTCCAATTAGGTATCAGTGCAGATATGGAAAAAGCAGGTGCTACTGGGAGCATTCCCAAATACCAGTTTTCTCACTTCCTGGAAGAAGATGAGCTTGTGGTCAGCCAAACTCAAGGAGAACTTGCATGGAAGGAGAAATGCAAACAGAGTGAAATCTCTAGAATCTGCTCTTTTTAATAAGAACTCATATCCT
>NM_020436.5
AATTACTGGGACATGCGCGTTCCGGCCGAAGGGGGGTAAATTTCCCAACTCCAGGAATTTGTGGCGGAGAGGGCAAATAACTGCGGCTCTCCCGGCGCCCCGATGCTCGCACCATGTCGAGGCGCAAGCAGGCGAAACCCCAGCACATCAACTCGGAGGAGGACCAGGGCGagcagcagccgcagcagcagACCCCGGAGTTTGCAGATGCGGCCCCAGCGGCGCCCGCGGCGGGGGAGCTGGGTGCTCCAGTGAACCACCCAGGGAATGACGAGGTGGCGAGTGAGGATGAAGCCACAGTAAAGCGGCTTCGTCGGGAGGAGACGCACGTCTGTGAGAAATGCTGTGCGGAGTTCTTCAGCATCTCTGAGTTCCTGGAACATAAGAAAAATTGCACTAAAAATCCACCTGTCCTCATCATGAATGACAGCGAGGGGCCTGTGCCTTCAGAAGACTTCTCCGGAGCTGTACTGAGCCACCAGCCCACCAGTCCCGGCAGTAAGGACTGTCACAGGGAGAATGGCGGCAGCTCAGAGGACATGAAGGAGAAGCCGGATGCGGAGTCTGTGGTGTACCTAAAGACAGAGACAGCCCTGCCACCCACCCCCCAGGACATAAGCTATTTAGCCAAAGGCAAAGTGGCCAACACTAATGTGACCTTGCAGGCACTACGGGGCACCAAGGTGGCGGTGAATCAGCGGAGCGCGGATGCACTCCCTGCCCCCGTGCCTGGTGCCAACAGCATCCCGTGGGTCCTCGAGCAGATCTTGTGTCTgcagcagcagcagctacagcagATCCAGCTCACCGAGCAGATCCGCATCCAGGTGAACATGTGGGCCTCCCACGCCCTCCACTCAAGCGGGGCAGGGGCCGACACTCTGAAGACCTTGGGCAGCCACATGTCTCAGCAGGTTTCTGCAGCTGTGGCTTTGCTCAGCCAGAAAGCTGGAAGCCAAGGTCTGTCTCTGGATGCCTTGAAACAAGCCAAGCTACCTCACGCCAACATCCCTTCTGCCACCAGCTCCCTGTCCCCAGGGCTGGCACCCTTCACTCTGAAGCCGGATGGGACCCGGGTGCTCCCGAACGTCATGTCCCGCCTCCCGAGCGCTTTGCTTCCTCAGGCCCCGGGCTCGGTGCTCTTCCAGAGCCCTTTCTCCACTGTGGCGCTAGACACATCCAAGAAAGGGAAGGGGAAGCCACCGAACATCTCCGCGGTGGATGTCAAACCCAAAGACGAGGCGGCCCTCTACAAGCACAAGTGTAAGTACTGTAGCAAGGTTTTTGGGACTGATAGCTCCTTGCAGATCCACCTCCGCTCCCACACTGGAGAGAGACCCTTCGTGTGCTCTGTCTGTGGTCATCGCTTCACCACCAAGGGCAACCTCAAGGTGCACTTTCACCGACATCCCCAGGTGAAGGCAAACCCCCAGCTGTTTGCCGAGTTCCAGGACAAAGTGGCGGCCGGCAATGGCATCCCCTATGCACTCTCTGTACCTGACCCCATAGATGAACCGAGTCTTTCTTTAGACAGCAAACCTGTCCTTGTAACCACCTCTGTAGGGCTACCTCAGAATCTTTCTTCGGGGACTAATCCCAAGGACCTCACGGGTGGCTCCTTGCCCGGTGACCTGCAGCCTGGGCCTTCTCCAGAAAGTGAGGGTGGACCCACACTCCCTGGGGTGGGACCAAACTATAATTCCCCAAGGGCTGGTGGCTTCCAAGGGAGTGGGACCCCTGAGCCAGGGTCAGAGACCCTGAAATTGCAGCAGTTGGTGGAGAACATTGACAAGGCCACCACTGATCCCAACGAATGTCTCATTTGCCACCGAGTCTTAAGCTGTCAGAGCTCCCTCAAGATGCATTATCGCACCCACACCGGGGAGAGACCGTTCCAGTGTAAGATCTGTGGCCGAGCCTTTTCTACCAAAGGTAACCTGAAGACACACCTTGGGGTTCACCGAACCAACACATCCATTAAGACGCAGCATTCGTGCCCCATCTGCCAGAAGAAGTTCACTAATGCCGTGATGCTGCAGCAACATATTCGGATGCACATGGGCGGTCAGATTCCCAACACGCCCCTGCCAGAGAATCCCTGTGACTTTACGGGTTCTGAGCCAATGACCGTGGGTGAGAACGGCAGCACCGGCGCTATCTGCCATGATGATGTCATCGAAAGCATCGATGTAGAGGAAGTCAGCTCCCAGGAGGCTCCCAGCAGCTCCTCCAAGGTCCCCACGCCTCTTCCCAGCATCCACTCGGCATCACCCACGCTAGGGTTTGCCATGATGGCTTCCTTAGATGCCCCAGGGAAAGTGGGTCCTGCCCCTTTTAACCTGCAGCGCCAGGGCAGCAGAGAAAACGGTTCCGTGGAGAGCGATGGCTTGACCAACGACTCATCCTCGCTGATGGGAGACCAGGAGTATCAGAGCCGAAGCCCAGATATCCTGGAAACCACATCCTTCCAGGCACTCTCCCCGGCCAATAGTCAAGCCGAAAGCATCAAGTCAAAGTCTCCCGATGCTGGGAGCAAAGCAGAGAGCTCCGAGAACAGCCGCACTGAGATGGAAGGTCGGAGCAGTCTCCCTTCCACGTTTATCCGAGCCCCGCCGACCTATGTCAAGGTTGAAGTTCCTGGCACATTTGTGGGACCCTCGACATTGTCCCCAGGGATGACCCCTTTGTTAGCAGCCCAGCCACGCCGACAGGCCAAGCAACATGGCTGCACACGGTGTGGGAAGAACTTCTCGTCTGCTAGCGCTCTTCAGATCCACGAGCGGACTCACACTGGAGAGAAGCCTTTTGTGTGCAACATTTGTGGGCGAGCTTTTACCACCAAAGGCAACTTAAAGGTTCACTACATGACACACGGGGCGAACAATAACTCAGCCCGCCGTGGAAGGAAGTTGGCCATCGAGAACACCATGGCTCTGTTAGGTACGGACGGAAAAAGAGTCTCAGAAATCTTTCCCAAGGAAATCCTGGCCCCTTCAGTGAATGTGGACCCTGTTGTGTGGAACCAGTACACCAGCATGCTCAATGGCGGTCTGGCCGTGAAGACCAATGAGATCTCTGTGATCCAGAGTGGGGGGGTTCCTACCCTCCCGGTTTCCTTGGGGGCCACCTCCGTTGTGAATAACGCCACTGTCTCCAAGATGGATGGCTCCCAGTCGGGTATCAGTGCAGATGTGGAAAAACCAAGTGCTACTGACGGCGTTCCCAAACACCAGTTTCCTCACTTCCTGGAAGAAAACAAGATTGCGGTCAGCTAAGGGAGAACTTGCGTGGAAGGAGCAATGCAGACACAGTGAAATCTCTAGAATCTGCTTTGTTTTGTAAGAACTCATCTCCTCCTGTTTTCTTTTTCTTACTGATATGCAAATGATGTTTACTACGTTGGTTGTGACCACAACCTCAGGCAAGTGCTACAATCACGATTGTTGCTATGCTGCTTTGCAAAAAGTTGAAAAAATAAAAAAAAAATGCATACCAAAACAAATACAGACTCtttttttttgagatggagtctcgctctatcacccaggctggagtgcagtggcatgatctcggctcactgcaacctccccattctgggttcaagtgattctcctgccttagcctccagagtagctgggattacaggcaggtgccaccacgcccggctaattttgtattttgagtagagactgggtttcaccatgttggtcaggctggtctcgaactgctgacctcgtgatccacccgccttggcctcccaaagtgctgggattacaggcatgagctaccacgcctggcACTTTTTTTTTTTTTTTCTAATTTTGGAAAGAAGCGGGTCTTGCAAAGTAGCTTTGTTACTTGTAACAGACGTATACATAGAACCTTTGTACAACCTAGAGTGACTTTTTCCAAAGACTGTTACCTATTTCAAGGTAGAATCGTTGGAACTTACTGAACAACAGTGGAAAAGACAACTACACAGCCTCATTGAGGGGAGATGGGTACTGTATACTTACTGGTAACTGGACACGGGTAAAAGGACAAGGTCTGTCATCTCTTTAGGGACCTGTTTTATATGCCCCAACCCTGTCCCCATCTTATTGTTTTTTTTTGAATGTACTTAAAAAAGGAACAACAAAAAACTAGGGTTGTAGAATTATAAAACTGCTTCAACCTTAGAACCTTAAGTAGGAGGCCCTCAAATGGACTTACGTTAGTCCTTAGGGAGTCAATGTGTGTGTTGCTGCTTATTTAAATACAGTTCAGTTGGAGCCCCGAGAGTGCCAATGTTTTCCCCACACCTCTTGGATGCCTTCCTCTTCCCAAATCCCAGAAGAGGTGGGCACCTGAGCGGGGAATCTCAGGTGACTTAGTTTGCCAGTGCCTACTCTATTGAAGAACTGGGTTTTCATGCTCGAGAAGAAACTCGTGGAAGGGCGTGTTTCCCATCACAGGTTCACATACTGATTGCTTTTGTTGAATTTCCTTGGTGCGACTTATGCCAAGTAATTATGACGATTTTTTGTTTTGTTTTGTTTCCTTGCTGAATATTTCATGAAGGCTACGAAGTTAGAACAGGCACGTCCTGGGTGTGAAAGCTTTAATTTATCTACCTCATTTATTTTTTATTTTTTGTAGCCATAGTGTCTATTTTCCTATTTTAAGACCGCTGAAGTATTCCCAGGCCCTGTCTAAAGCCTAAGAGTTGATGTATTGGTGGGAAGAGGTGAACGTTCAAGATGATTTTGTGATGCCTTTTTTTTTTGTAGTTTCCTTTGTAAATGTGATATTGAGCAAACGAAACATTGCTCTTGGTTTAACAAGAAAGAAAGAAAAAAACTCTAATTTCTGGGAGAAAAGTCTTTCCCCTCTATGTGGAAGGTCCTGACGGAAATATGCATCCAAGACGATTAGCCAAAGTGTTGTCTCTTCATCGTTGCACCTGACTTTAGGATTCCGCCCCCCttttttttttttttttttttttttGCCAAGTTGTGCCTTTCCTTCTGGAATTGTAAGTGAACACGATAATAGTACCTGTTTACACTGTGAAGTGGATATTGTTACAGAAAACACACCAGTGGCTTTCTCACTGTTGAGCTAATAATGCCTTGTGAATGTATGATCTACGGAGAAACCCCTGTAGTTGTACCTGCTGATGCTGTCTGTCTGTTGGAAAATAAAATTTGAATGTTTTTTTTTCTCA

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