Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name CNN2P16
Plot displaying the genomic locations of a retrocopy (in chr16) and its respective parental gene (in chr19). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr16:68650755-68651950  UCSC
Coordinates (T2T) chr16:74447050-74448245  UCSC
Coordinates (hg19) chr16:68684658-68685853  UCSC
Strand -
Parental Sequence NM_004368.4
Parental seq. overlap 910 bp
Parental seq. overlap (%) 39.8%
Genomic Region Intragenic (CDH3)
Intragenic (CDH15)
Retrocopy Summary CNN2P16, located on chr16:68650755-68651950, is a retrocopy of the parental gene CNN2. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name CNN2
Full Name calponin 2
Also known as -
Coordinate chr19:1026608-1039065
Strand +
Gene summary The protein encoded by this gene, which can bind actin, calmodulin, troponin C, and tropomyosin, may function in the structural organization of actin filaments. The encoded protein could play a role in smooth muscle contraction and cell adhesion. Several pseudogenes of this gene have been identified, and are present on chromosomes 1, 2, 3, 6, 9, 11, 13, 15, 16, 21 and 22. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2015]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes CNN2P9
Orangutan Pongo abelii CNN2P6
Gibbon Nomascus leucogenys CNN2P1
Crab-eating macaque Macaca fascicularis CNN2P7
Rhesus Macaca mulatta CNN2P9
Golden snub-nosed monkey Rhinopithecus roxellana CNN2P14
Marmoset Callithrix jacchus CNN2P19
Bonobo Pan paniscus Without Homology
Gorilla Gorilla gorilla Without Homology
Green monkey Chlorocebus sabaeus Without Homology
Baboon Papio anubis Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>CNN2P16
AACCTGTTCAATGTTGCCAATCAACTGAGGGTCTGTGAGTGGCGTCATGGGATGTGGCAGCAGGGATATTCCCCCCTTGCCTTGGTTCCTTCACAGAACTGGGCCACCAGGCTGTGGGGGAAGGGGTTAAGGCTGTATCCCGAAGCATGTAGGGTGAGGGTCCCTGCTGGCACGTCCAGGCTACTCCATGCAATTCAACAAGGGCCCCTCATACTGGCTCTCCGCCGAGGTCAAGAACCGGCTCCTGTCCAGATATGACCCCCAGAAGGAGGCAGAGCTCCACAGCTGGATCGAGGGACTCACCAGCCTCTCCATCAGCCCTGACTTCCAGCAGGGCCTGAAGGACAGAATTATCTTACACACACTCATGAACGAGCTGCAGCCAGGCTCAGTCCCCTAGATCAACCACTCCATGCAGAACTGGCACCAGCTAGAAAACCTCTCCAACTTCATCAAGGCCATAGTCAGCTATGGCATGAACCCCATGGACCTGTTTGAGGCCAGTAACCTGTTTGAGAGTGGGAACATGATGCAGGTGCAGGTGTCTCTTCTTGCCCTGGCGGGGAAGGCCAAGACTAAGGGGCTGCAGAGCGGGGTGGACATCAGTGTCAGGTACTCAAAGAAGCAGGAGCAAAACTTCGACTAGAACACCATGAAGGCCGGCCAGTGCGTCATCGGGCTGCAGATGGGCACCAACAAATGTGCAAGCCAGTCGGGTATGACCATGTACGGCACAAGGAGGCATCTCTACAGCCCCAAGAACCATATCCTGCCCCCGTGGACCACTCGACCATCAGCCTCCAGATGGGTACAAACAAGTGCGCCAGCCACATGGGCATGACGGCTCCCTGGACCCAGCTGCACATCTATGACACCAAGCTGGGCACCAACAAGTATGACAACTCCTCCGTGTCCCTGCAGATGGGCTACCTGCAGGGTGCTAACCAGAGCAGCCAGGTCTTTGGCCTGGGCCGGCAGATATACAATTCCAACTACTGCCCACAAGGCCCAGTGGCCAACAGGGCTCCCTCGGGCACCAACGACTGCCCAGGCCCAGGGAAGGCCCCTGAATATCCCCCTTACTACCAGGAGGAGGCCAGCTACTAAGGCTCCCAGCACGCTCTCTCCCCACATCGTCTCCCTGTCTGGGt
>NM_004368.4
ggtcccgtcccgtcccgtcctgtgcggccccgtcccgccgcccgcccgccagccATGAGCTCCACGCAGTTCAACAAGGGCCCCTCGTACGGGCTGTCGGCCGAGGTCAAGAACCGGCTCCTGTCCAAATATGACCCCCAGAAGGAGGCAGAGCTCCGCACCTGGATCGAGGGACTCACCGGCCTCTCCATCGGCCCCGACTTCCAGAAGGGCCTGAAGGATGGAACTATCTTATGCACACTCATGAACAAGCTACAGCCGGGCTCCGTCCCCAAGATCAACCGCTCCATGCAGAACTGGCACCAGCTAGAAAACCTGTCCAACTTCATCAAGGCCATGGTCAGCTACGGCATGAACCCTGTGGACCTGTTCGAGGCCAACGACCTGTTTGAGAGTGGGAACATGACgcaggtgcaggtgtctcttctcgccctggcggggaagGCCAAGACTAAGGGGCTGCAGAGCGGGGTGGACATTGGCGTCAAGTACTCGGAGAAGCAGGAGCGGAATTTCGACGATGCCACCATGAAGGCTGGCCAGTGCGTCATCGGGCTGCAGATGGGCACCAACAAATGCGCCAGCCAGTCGGGCATGACTGCCTACGGCACGAGAAGGCATCTCTATGACCCCAAGAACCATATCCTGCCCCCCATGGACCACTCGACCATCAGCCTCCAGATGGGCACGAACAAGTGTGCCAGCCAGGTGGGCATGACGGCTCCCGGGACCCGGCGGCACATCTATGATACCAAGCTGGGAACCGACAAGTGTGACAACTCCTCCATGTCCCTGCAGATGGGCTACACGCAGGGCGCCAACCAGAGCGGCCAGGTCTTCGGCCTGGGCCGGCAGATATATGACCCCAAGTACTGCCCGCAAGGCACAGTGGCCGATGGGGCTCCCTCGGGCACCGGCGACTGCCCGGACCCGGGGGAGGTCCCTGAATATCCCCCTTACTACCAGGAGGAGGCCGGCTACTGAGGCTCCCAGCACGCTCTCTCCCCACATCGTCTGCCCATCTGGGtttttgggtttttctgtgttttcatcttttttttttttttcttAACCCGTTCAGTGCTGCCAGTCAACCAAGGGTCTGTGAGTGTCAGCGTGGGATCAGGCAGCAGAGCTTTTTTCCCCTTTGCCTTGATCCTTCGCAAGGCTGAGCCACTGGGCTGTGGGGGAAGGGGTCAAGGCCATATCCCAATACGTGTAGGGCGAGGGTCCCTGCTGGCACATTCAGGCTGTGCTGGGAAGAAGAGACCTGGGCTTGGAAGGAACCGGTCCCCGACGGTTTCTGCTTGCCTCGCCTCTTCCCCCTTTTGTCAGCTGAGCAGTTTGTGGTTTCTATGCCCGCAAGTTTCAGGAAGTATTCACAAAAGAAAAATACATTTTTTCCCCCAGGGGTGGGGCAAGGACAGTGGAGAGAGTGCTAGGAAATGAGTCCCCTGGGAAAGGGGACCGGGCCGTGATGTTAAATATCTCCGGCTCCCAAGTGACTGGATTTGCCTAGGACCTTCAGACCAACAGACTTCAGACCCTCAGACCTGCCCCGGGGCCAGGTGGAGAAAGTGAGGGCCGTACAAGGAAGTGAAATTCTGAGTTGTTGGGGCTAAGCCTGACCCCCTCTCCATGCTCCCCGCCCCAACCCACTCTGGCCTCAGTAGAtttttttttcagttgtggttgttgcccaggctggagtgcagtggcgccatcttggctcactgcacctccaccttccgggctcaagcgattctccagcctcagcctcctgagtagctaggactgcaggtgctccaccacgcccggctaatttttgtatttttagtagagatggggtttccccatgttggccaggctggtctcgaactcctggcctcaggtgtgatccgcccgcctccgcctccccaagcgctgagattacaggtgtgagccaccgtgcccagccCCTCAGTAGGTTTTAAGGAGCCCCCAGCCCTCCTCCCTTCTGGGCCCGACCAGCTTATACTGCTCCATCTTCCCCGGCCACATGCCCCGCCAAGTACTGCACAGGGACCCCCCACCCAGGGGACCTGCTCCGTGAGATAATGTGAAATACGACTGTGGACCAAACGCAATAAAACCTCTGTTTGTACGAAGA

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