Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name TSEN15P1
Plot displaying the genomic locations of a retrocopy (in chr17) and its respective parental gene (in chr1). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr17:17456400-17459574  UCSC
Coordinates (T2T) chr17:17401575-17404747  UCSC
Coordinates (hg19) chr17:17359714-17362888  UCSC
Strand +
Parental Sequence NM_001300764.2
Parental seq. overlap 1449 bp
Parental seq. overlap (%) 73%
Genomic Region Intergenic
Retrocopy Summary TSEN15P1, located on chr17:17456400-17459574, is a retrocopy of the parental gene TSEN15. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name TSEN15
Full Name tRNA splicing endonuclease subunit 15
Also known as C1orf19|PCH2F|sen15
Coordinate chr1:184051730-184097485
Strand +
Gene summary This gene encodes a subunit of the tRNA splicing endonuclease, which catalyzes the removal of introns from tRNA precursors. Alternative splicing results in multiple transcript variants. There is a pseudogene of this gene on chromosome 17. [provided by RefSeq, Jul 2014]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes TSEN15P3
Bonobo Pan paniscus TSEN15P3
Gorilla Gorilla gorilla TSEN15P2
Orangutan Pongo abelii TSEN15P3
Gibbon Nomascus leucogenys TSEN15P2
Green monkey Chlorocebus sabaeus TSEN15P1
Crab-eating macaque Macaca fascicularis TSEN15P3
Rhesus Macaca mulatta TSEN15P3
Baboon Papio anubis TSEN15P3
Golden snub-nosed monkey Rhinopithecus roxellana TSEN15P4
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>TSEN15P1
CACCACGGGAGCGCCGCACCAGCCGGCATGGAGGAGCGTGGCAATTTCAAGCTGACCCCTGGCTGCAGTGGCCTGGGTCTGTGTGGCGTTCGCGGCTTTGGCGACTGCGGTGGAGCTCCCTCGTGGGTCCCCGAGGACGCCTGGATGGGCACCCACCTTAAATATTTAGAAATGATGAAATTATGATGGAACTAGACACAGAAGATGCCACCCATGTTTATATAGCATTCTTGGTTTATCTGGACCTCATAGAAAGCAAAACTGGCATGAACTAAACTGTGTCAGATTACCAGAACTCCAGCTCATCTGCCTTGTTGGTACTGAGATAGAAGAGGAGGGGTTACAGACTGTGGTGCCTACCCCCATCACTGCTTCCCTCAGCCATAACAGGATAAGGGAGATCTTGAAGGCATCTTGAAAATTGCCAGGTGATCCAGATTTGCTGATGTCTTTTACTCTGGCCATAATGGAGTCTGATTCTACAATAGTCTATTATAAACTTACTGATGGATTTATGCTGCCAGACCCTCAGAATATTTCTCTTAGAAGATGACATCTATGTTTCCTGATGCTTGTTTTATTCATACAAGATTGGATTTGAGACCCGTCAGACTGCTTTGTCTTTTATCTCAGAGATAGTCAGGGTTGACTTAGATAGTGAGGGTTGACTTCCCTATTCCATAAGGTTTTCATTCTGAAGAATAAAACTTCCCCAGGGGGCCTCTCCAGGTAGAAGACTTTTTCTTTCTTAAAAAATATAGGTGGTTTCTTTACAACTTTCTTATCTAGAGACAGTTTAATTACAGTTGTATACAGGTTTACGCCTAGGATGTGTTCAGACAGGTGGAACCTGTGTGCTGCTTTTGTCATCCCACACTTATAGCACTCATAGTTGCCTCTGTTTATTGCTCCCACTGCTAGCTCATTGTTGAGACTGCCATCTCTTTCTCTTACTCAACTCTCCCAGTGCCTTTTGGCCACTGCAGCTACCTTGGAATGGCATTTTATACATACCTTGTCACCTACTTCTGCTTTTTCCTACCCAGTAGAAGGTAAAAGATTTCTTTCAATTGGTCCTCCTGTTGCAATGACTGTTATTTCTCTTTTTTGGTTAACTTTAAATCAAAACTCAAAATATGTTCATCCAGAGTGTAAACTTACATGTCCTGAGTAACAGGGATAGGAGACATGCTACCCACAAGAGTTCTGGGCCTTCCTTTTCATTCTTATTACCACCATCCTTATTATATCATAGCTTGAATATTACAAGAGAGATAGTGTGGGACAGTATCAGTTTTTTGTGTTGCCATAGTTTGCCATCCCTGGGTCTAGGAAATAGTCGATAAACAGGTATATACAAACGATACATAATGTACTTATTAAAAATTAGaTGAATATTATTAAAAACATGAGAATTTTACATTAAGTAAAATTTGCAAGATGCAAAAGTGTATGAGTGGGTGTAATCATGGCTGAAATAACACATCAAGCATTTGATAACAAGATGACAAAGTAAATCAAATTACTAACTGTGGTTACAGTGGGATGGGAGGCAGTAAATGGATGACTTTGTCTTTTCTCAATGTTTATTTTTATTTGTATTACTTTTATAATAAAAATGTTTTAAAATT
>NM_001300764.2
ACCACGGGAGCGCCGCACCGGCCGGCATGGAGGAGCGCGGCGATTCCGAGCCGACCCCCGGCTGCAGCGGCCTGGGTCCGGGCGGTGTTCGCGGCTTTGGCGACGGCGGTGGAGCTCCTTCGTGGGCCCCTGAGGACGCCTGGATGGGCACTCACCCTAAGTATCTAGAAATGATGGAATTAGATATAGGAGATGCCACCCAAGTTTATGTAGCGTTCTTGGTTTACCTGGACCTCATGGAAAGCAAAAGCTGGCATGAAGTAAACTGTGTAGGATTACCAGAACTCCAGCTCATCTGCCTTGTTGGTACTGAGATAGAAGGGGAGGGGTTACAGACTGTGGTGCCTACCCCCATCACTGCTTCCCTCAGCCATAACAGGATAAGGGAGATCTTGAAGGCATCTCGAAAGTTGCAAGGTGATCCAGATTTGCCGATGTCTTTTACTTTGGCCATAGTGGAGTCTGATTCTACAATAGTCTATTATAAACTTACTGATGGATTTATGCTGCCAGACCCTCAGGTCAGTTTTGAGAATATTTCTCTTAGAAGATGACATCCATGTTTCCTGATGCTTGTTTTATTCATACAAGATTGGATTTGAGACCCATCAGACTGCTTCATCTTTTATCTCAGAAATAGGGTTGACGTACATAGTGAGGGTTGACTTCCCCATTCCATAAGGTTTTCATTCTGAAGAGTAAAACTTCCCCAGGTAGAAGACTTTCTCCTTCTTAAAAAATATAGGGTGATTTCTTTAAAACTTTGTTATCTAGAGACAGTTTAATTACAGTTATATACAGGTTTATGCCTAGGATGTATTCAGATGGGTGGGACCTGTGTGCTGCTTTTGTCATCCCACACTCAAAGTTGTCTCTTTGTTTCTTGCTGCCACTGCCAGCTCATTGTTGAGACTGCCATTTCTTTCTCTTACTCAGCTCTCCCCAGTGCCTTTTGGCCACTGCAGCTACCGTAGAATGGCATTTTATATGTACCTTGTCACCCACTTCTGTTTACTTTTTCCTCTCCAGTAAAAAGTAAAAGATTTCTTTCAATTGGTCTTCCCATTGCAGTTACTGTTATTTCTCTTTTTTGGTTAACTTTAAATCAAAACTCAAAATATGTTCATCCAGAGTGTGTCTTAAGTAACTTACGTGTCTTAAGTAACAGGGACCAGAGACATGTTACCTACAAGAGTTCTGGGCTATCCTTTTCATTCTTATCACATATCATAGCTTGAATATTACAACAGTGTGGGAGAGAATCaaccgtaaaaatgtcttcattaattagacccagttattccacttttgttaatgtctctcaaattgtacaaagtataaaaaattatatgcacaaagatgttccaagtgacattacttttagtagcccaaattataaaccactttaaagtTTGGGGTAAAgattggcaaactttttctataaagggccagaaagtaactattttaggtttttaaacctactgtctctgtcataacttgtcaacactgctgtatgaagcacaaaagcagccatagacaatacataaacaatacgggcgtggctttgttccagtaaaactttgtttacaaaTGTGGTGCCATAGTTTGTCATCCCTGGGTCTAGGAAATAGTCAATAAACAGATATATACAAATGATACATAATGTACTTATTAAAAATTAGTAATGAATATTATTAAAAACATGAAAATATTACCTTAAGTAAAAATTGCAAGACGGAAAAGTGTATAAGTGGGTGTAATCATGGCTGAAATAACAGACCAAGCATATGATAAAAAGATAACAAAGTAAATCAAATTACTAACTGGTTATAGTGGGATAGGAGGCAGAAAATGGATGACTTTGTCTTTTCTCAATGTTTTTATTTGTATTTTATAATAAAAATGTTTTAAAATTAAAA

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