Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name STX18P1
Plot displaying the genomic locations of a retrocopy (in chr17) and its respective parental gene (in chr4). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr17:30068603-30070231  UCSC
Coordinates (T2T) chr17:31011940-31013568  UCSC
Coordinates (hg19) chr17:28395621-28397249  UCSC
Strand +
Parental Sequence NM_016930.4
Parental seq. overlap 1497 bp
Parental seq. overlap (%) 68.1%
Genomic Region Intragenic (EFCAB5)
Retrocopy Summary STX18P1, located on chr17:30068603-30070231, is a retrocopy of the parental gene STX18. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name STX18
Full Name syntaxin 18
Also known as Ufe1
Coordinate chr4:4418968-4542343
Strand -
Gene summary This gene encodes a member of the syntaxin family of soluble N-ethylmaleimide-sensitive factor attachment protein receptors (SNAREs) which is part of a membrane tethering complex that includes other SNAREs and several peripheral membrane proteins, and is involved in vesicular transport between the endoplasmic reticulum (ER) and the Golgi complex. The encoded protein is important for the organization of the smooth, rough, and exit site ER subdomains. A pseudogene of this gene has been identified. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2016]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes STX18P1
Bonobo Pan paniscus STX18P1
Gorilla Gorilla gorilla STX18P1
Orangutan Pongo abelii STX18P1
Gibbon Nomascus leucogenys STX18P1
Green monkey Chlorocebus sabaeus STX18P1
Crab-eating macaque Macaca fascicularis STX18P1
Rhesus Macaca mulatta STX18P1
Baboon Papio anubis STX18P1
Golden snub-nosed monkey Rhinopithecus roxellana STX18P1
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>STX18P1
TTGTGGGGCTGCCTGTGCGGGTCGCTAGGGCGGTGGACATCACGCTGCTATTCCGGGCCAGCGTCAAGACCGTGAAGACGCAGAACAAGGCACTGGGAGTGGCAGTGGGTGGCAGAGTCGATGGCAGCCGGGATGAGCTGTTCCGCAGGAGTCCCTGGCCCAAGGGCAACTTCTCCAGCCGGGCCCGCGAAATGATTTCTCACAGTGGCAAACTGAGAGATTTTCTTCTGGAACACAGGAAAGATTATATTAATGCTTATAGCCATACCATGTCTGAATATGGGAGGATGACAGACACAGAACGAGACCAAATAGACCAGGATGTCCAGATATTCATGAGGACCTGTTCAGAAGCAATTCAACAACTACGAACAGAAGCTCACAAGGAGATACATTCCCAGCAAGTGAAGGAGCACAGGACTGCTGTTCTGGATTTCATTGAAGATTACTTAAAAAAAGTGTGTAAACTTTACTCAGAACAAAGAGCCATCCGAGTTAAAAGAGTGGTGGATAAGAAAAGAATATCTAAGCTGGAACCAGAACCAAATGCAAAGACAAGAGAATCCACATCTTCTGAGAAAGTTTCACAGTGTCCTTCAAAAGACTGAAGAAAACCCTGCCACTGAAGAACATCCAGAAAAGATTTTGACTGAAAGACAACCTGAATTGGGAACATGGGGAGATGGCAAAGGTGAAGATGAGTTATCCCCAGAAGAAATACAAATGTTTGAACAGGAAAATCAGCGACTAATTGGTGAAATGAACAGCTTGTTTGATGAAGTGAGGCAGATCAAAGGGAGAGTGGTTGAGATTTCCAGACTTCAAGAGATATTCACGGAAAAGGTTTTGCAACAGGAAGCTGAGATTGATGGCGTTCACCAGTTAGTTGTGGGGGCAACTGAAAATATCAAGGAAGGCAACGAAGACATAAGAGAGGCCATTAAAAACAACGCTGGCTTCCGCGTATGGATCCTCTTCTTCCTCGTGATGTGCTCCTTCTCCTTGCTCTTCCTCGACTGGTACCACAGCTAGCCTGGGCCACGGGGGCCCAGCACGAGAGTCTGCATGGGCGCTCACAGGCTGTGTACTCTCATGTACCCGCCGTAGTCTCATGTACCCCCGGTGCTGGAGCATGGTATGACCACATTTTATCACAGAGCCATTTTAAGAGAAAGGGGTTCAGACAGACGGACATATTCCCCAAAAAGGGATACCCAGGCCGATAGTGTTCAGCCCATTTCGCAGCTGAAAAAGAAAACACTGCACACCAATGGGAAGTGGCCTATGTAGCTATCATAAGGCTAGACAAACTGAATGCTGGAGCTGGTGATTAGCTGCTCCTGAACTTGAGGCCGCCTTGGCAGGGGGGGCTGCTCCAGTAGCAGGGGCACAGCAGGCCTCCAGAGCCCCCAGTTGTCTCAGGGTTCAAAGGAAGTCACTGACCTTTCCCATCCCAGTAGCTTCAGGGAAGAACATAGTTTAATAACGTCTCTCAACAAATGATTACTTCTTTGTTTCCTTGTGGCTTCTTGTCTGTCTGAGTCAACCAATAAACAGACTCACTGGATTATAGAAAAGAAAATTCACATTTGCCTTATTAATCTAATAAATACAATTACAGCCCCTTAA
>NM_016930.4
AGTCCTTCAGCGGCCGGGTTCGCGCCGCGGTCGCCGGCTGCTTACGTGGGCGGGCCTAGTGTGGGGCTGAGGGTGCGGGTCGCTATGGCGGTGGACATCACGCTGCTATTCCGGGCCAGCGTCAAGACCGTGAAGACGCGGAACAAGGCGCTGGGAGTGGCGGTGGGCGGCGGGGTCGATGGCAGCCGGGACGAGCTGTTCCGCCGGAGCCCCCGGCCCAAGGGCGACTTCTCCAGCCGGGCCCGCGAAGTGATTTCTCACATTGGCAAACTGAGAGATTTTCTTCTGGAACACAGGAAAGATTATATTAATGCTTATAGccataccaTGTCTGAATATGGGAGGATGACAGACACAGAACGAGACCAGATAGACCAGGATGCCCAGATATTCATGAGGACCTGTTCAGAAGCAATTCAGCAACTACGAACAGAAGCTCACAAGGAGATACATTCCCAGCAAGTGAAGGAGCACAGGACCGCTGTTTTGGATTTCATTGAAGATTACTTGAAAAGAGTATGTAAACTTTACTCAGAACAGAGAGCCATCCGAGTTAAAAGAGTGGTGGATAAGAAAAGATTATCTAAGCTGGAACCAGAACCAAATACAAAGACAAGAGAATCCACATCTTCTGAGAAAGTTTCACAGAGTCCTTCAAAAGACTCTGAAGAAAACCCTGCCACTGAAGAACGTCCAGAAAAAATTTTGGCTGAAACACAACCTGAATTGGGAACGTGGGGAGATGGCAAAGGCGAAGATGAGTTATCCCCAGAAGAAATACAAATGTTTGAACAGGAAAATCAGCGACTAATTGGTGAAATGAACAGCTTGTTTGATGAAGTGAGGCAAATCGAAGGGAGAGTGGTTGAGATTTCCAGACTCCAAGAGATATTCACGGAAAAGGTTTTGCAACAGGAAGCTGAGATTGACAGCATTCACCAGTTAGTTGTGGGGGCAACTGAAAATATCAAGGAAGGCAACGAAGACATAAGAGAGGCCATTAAAAACAACGCTGGCTTCCGCGTGTGGATCCTCTTCTTCCTCGTGATGTGCTCCTTCTCCTTGCTCTTCCTCGACTGGTACGACAGCTAGCCAGGGCCACGGGGGCCCAGCACGAGAGTCCTCATGGGCACTCACAGACTGCGTGCTTTCATGTACTTCCAGTGCTGGAGCATGGTATGACCAGATTTTATCACAGTGCCATTTGAAGGGAAAGGAGTTCAGACAGACAGACGTATTCCCCAAAAAGGGATACCCCAGGCCGATGGTGTTCAGCCATTTAGCAGCTGAAAAAGGAAACAGTGCACACCAATGGGAGGCAGCCTGCGTAGCCCTCATCAGGCAAGACAGACTGAATGCAGGAGTGGGTGATTAGCTGCTCCTTGAACTTGAGGCTGCCTTGGCAGCAGGGGCACAGCAGGCCTCAAGAGCCCCTAATTGTCTCAGGGTTCAAAGGAAGACACTGACCTTTCCCATCCCGGTAGCTTCAGGGAAGATCATAGTTAATAACGTCTCTCAACAAATGATTACTTCTTTGTTTCCTTGTGGCTTCTTGTCTGTCTGAGTCAACGAATACACAGACTTACTGGATTATAGAAGAGAAAATTCACATCTGCCTTGTTAATCTAATAAATATAATTACAGCCCCTTAATGTGTTGTCAATGAGTCTAAGTTGACAAATTCAGTGGCAGCCCAGCCACCTCCTATCAATCAATCAGGGAAGAAATGCAGGGGAGACTGGGGCCCTCAGTGAGGGGCTGCCTGGCATTACTCCTCCAAAGACTGCTGCCCCCAGAACAGGCAGGGGGTGTGGGAGGGCCAGTTTCCCGCCACTGGGTCCAAGGAGCCTTTGTTCAAAGGAAGAAGTGGGCCACGGAAGAACGGGCCTGCTTCTCTCGTGCCTGTGCTTCTGACCTCCAGGAACTGTAAACAGGAACACCTATGTGTAACTGAAGGCATGAGACATCTGTACAGGAAGCATCCCAGCGCCCACATGGGCATGAGACAGTCTGCACTGCGCCTGGTGAAATGCGTGTGTGTACAGACAGTCCACTGGGCAGCACAGGTATCCTCATGTTCTTTATTTGCACAGAGTGAAATGTCAGAAGTTACATGTAAATGAATTCACAGTCAATAAAGTCCACGTCTACCTGGAAA

Publications

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