Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name SNX6P1
Plot displaying the genomic locations of a retrocopy (in chr19) and its respective parental gene (in chr14). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr19:23125840-23127804  UCSC
Coordinates (T2T) chr19:23260964-23262929  UCSC
Coordinates (hg19) chr19:23308642-23310606  UCSC
Strand -
Parental Sequence NM_152233.4
Parental seq. overlap 1809 bp
Parental seq. overlap (%) 54.7%
Genomic Region Intragenic (ZNF730)
Retrocopy Summary SNX6P1, located on chr19:23125840-23127804, is a retrocopy of the parental gene SNX6. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name SNX6
Full Name sorting nexin 6
Also known as MSTP010|TFAF2
Coordinate chr14:34561093-34630148
Strand -
Gene summary This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein associates with the long isoform of the leptin receptor, the transforming growth factor-beta family of receptor serine-threonine kinases, and with receptor tyrosine kinases for platelet-derived growth factor, insulin, and epidermal growth factor. This protein may form oligomeric complexes with family member proteins through interactions of both the PX domain and the coiled coil regions of the molecules. Translocation of this protein from the cytoplasm to the nucleus occurs after binding to proviral integration site 1 protein. This gene results in two transcripts encoding two distinct isoforms. [provided by RefSeq, Jul 2008]

Homology

Species Scientific Name Retrocopy
Orangutan Pongo abelii SNX6P1
Gibbon Nomascus leucogenys SNX6P1
Chimpanzee Pan troglodytes Without Homology
Bonobo Pan paniscus Without Homology
Gorilla Gorilla gorilla Without Homology
Green monkey Chlorocebus sabaeus Without Homology
Crab-eating macaque Macaca fascicularis Without Homology
Rhesus Macaca mulatta Without Homology
Baboon Papio anubis Without Homology
Golden snub-nosed monkey Rhinopithecus roxellana Without Homology
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>SNX6P1
GGAGCAGCCAGGATGGAAGACCTGGACGATGGCCCTAACTTCCTCTCAGGAAGAGAACTGTGGACTTAAAGCAATAAATGTAGATCTTCAAAGTGATCCTGCTCTGCTGGTGGACATTTCTGATGCTCTTAGTGAGCGGAATAAAGTAAAATTCACCATTCACACAAAGAGTTTATTGCCAAATTTTAAACAAAATGAGTTTTCTGTTGTTCAGCAACATGAGCAATTTATCTGGCTTCATGATTCCTTTGTTAAAAATGAAGACTATGCAGGTTACATCATTCCACCAGCACCACCAAGAGCTGATTTTGATGCTTCAAGGGAAAAAGTACAGAAGCTTGGAGAAGGAGAAGGGTCAATGACAAAGGAAGAATTCACAAAGATGAAACAGGAACTGGAAGCTGAATATTTGGGAATATCCAAGAACACAGTTGTGATGCATGAAGTGTTCCTATGTCATGTGACAGCACATCCTATTTTGAGAAAATATTTAAATTTCCATGTCTTCTTGGAATATAATCAAGATTTGAGTGTGCAAGGAAAAATAAAAAGAGAAACTTGAAGATTTCTTTAAAAACATGGTTAAATCAGCAGATGGAGTAATTATTTCCGGAGTAAAGGATGTAGATAATTTCTTTGAGCATGAACAAACATTTCTTTTAGAATATCATAACCGAGATAAGGATGCATCTGCTAACTCATAGAAGGACAAGATCCCACAAAAGTGCTGCAGATTATTACAATAGAATTGGTTCTTCATTATATGCTTTAGGAACTCGGGATTCTACAGATATACGCAAGTTTTTTCTCAAAGTTTCAGAAATGTTTGATAAAACAAGAAAAATAGAAGCATGAGTGTCTGCTGATGAGGACCTCAAACTTTCTGACCCTTAAAAATATTACTTAAGAGAAACTCAAGCTGCTAAGGATCTCCTGTATTGAAGGTCTAGGTCACTACTGGATTATGAAAATGCTAATATAGCACTGGATAAAGCAAGAGCAAAAAATAAAGATGTTCTGCTGGCTAAAACTTCCCAACAATTATGTAGTCAGAAATTTGAAAAAAAAAAATCTCAGTCTGCAAAACAAGAACTTATAGATTTTAAGACAAGAAGCATTGCTGCATTCAGAAAAAAAAAAAAACTAGTGGAACTGGCAGAGTTAGAACTGAAGCATGCAAAGGGTAACCTACAGTTGCTGCCAAACTGCCTGGCAGTGCTAAACGGAGACACATAAGCCACATTCTGCCTTCCTGTTGAAAAGGGCTGCCTTCCTTCAAATTTTATTTTTGTTTTCTTAATGATGTTACGCATTTATGCTCACTGGAAACAAATAAAAAACAGCTGACAAAATGGATCTACTCTTTTTCTGAGAAGCATGGAGCAGCACCATGTACAGGCGATGCCAGTCTGTGTGGTGTAATGCCGCACTGTGTTCCCCAAGATAGTGGCCCATTATTGTGCACTCATCATACTCAGAAGTCCAAGTTTTATTCTTCTTTAAAGTAGCCTCTATAACTGCATTTATTTTATAAATAGTATTCCTTATGGATGCCAATCTTATTTACCTTTAAATAATTTCTGAAGTTTAACCTTTTCAGAATGCATTGTTCAAACAAGATAAAGATTGCCTTTATTGCCTTTAAAACAGAATTTTTTAAAATTTTGTTTTAAAAAAGCATTATATACCACCTTAGTTCATTCATGTATCCTGGTAAAGCATCTTAATCAGACTTATTTTTAACTACTGAATATTTCTTAGAAGTTTTGGTACAGATTTTATGTAATCTTTATGATTTCTGAAGAAAAGCAAATGCATTAGTATGTTTGCCTTAAACTTGTAGACTAAACCAATTATTGTAAAATAAACAGCAATAACAGTGAGAGTTTTTAACTCTGTGGTCACTGTATCACTCTTCAACATTTGGAGTAGCTATAATAAATCTACTCCTGCATTATGCTTTAA
>NM_152233.4
GCGCCTGCGCCGGCCCTCGCCTCGGAGCAGCCATGATGGAAGGCCTGGACGACGGCCCGGACTTCCTCTCAGAAGAGGACCGCGGACTTAAAGCAATAAATGTAGATCTTCAAAGTGATGCTGCTCTGCAGGTGGACATTTCTGATGCTCTTAGTGAGCGGGATAAAGTAAAATTCACTGTTCACACAAAGAGTTCATTGCCAAATTTTAAACAAAACGAGTTTTCAGTTGTTCGGCAACATGAGGAATTTATCTGGCTTCATGATTCCTTTGTTGAAAATGAAGACTATGCAGGTTATATCATTCCACCAGCACCACCAAGACCTGATTTTGATGCTTCAAGGGAAAAACTACAGAAGCTTGGTGAAGGAGAAGGGTCAATGACGAAGGAAGAATTCACAAAGATGAAACAGGAACTGGAAGCTGAATATTTGGCAATATTCAAGAAGACAGTTGCGATGCATGAAGTGTTCCTGTGTCGTGTGGCAGCACATCCTATTTTGAGAAGAGATTTAAATTTCCATGTCTTCTTGGAATATAATCAAGATTTGAGTGTGCGAGGAAAAAATAAAAAAGAGAAACTTGAAGACTTCTTTAAAAACATGGTTAAATCAGCAGATGGAGTAATCGTTTCAGGAGTAAAGGATGTAGATGATTTCTTTGAGCACGAACGAACATTTCTTTTGGAGTATCATAACCGAGTTAAGGATGCATCTGCTAAATCTGATAGAATGACAAGATCCCACAAAAGTGCTGCAGATGATTACAATAGAATTGGTTCTTCATTATATGCTTTAGGAACTCAGGATTCTACAGATATATGCAAGTTTTTTCTCAAAGTTTCAGAACTGTTCGATAAAACAAGAAAAATAGAAGCACGAGTGTCTGCTGATGAAGACCTCAAACTTTCTGATCTTTTAAAATATTACTTAAGAGAATCTCAAGCTGCTAAGGATCTCCTGTATCGAAGGTCTAGGTCACTAGTGGATTATGAAAATGCTAATAAAGCACTGGATAAAGCAAGAGCAAAAAATAAAGATGTTCTACAGGCCGAAACTTCCCAACAATTATGTTGTCAGAAATTTGAAAAAATATCTGAGTCTGCAAAACAAGAACTTATAGATTTTAAGACAAGAAGAGTTGCTGCATTCAGAAAAAATTTAGTGGAACTGGCAGAGTTAGAACTGAAGCATGCAAAGGGTAATCTACAGTTGCTGCAGAACTGCCTGGCAGTGTTAAATGGAGACACATAAGCCACACTCCGCCTTCCTGTTAAAAAGGGCTGCCTTCCTTCAAATTTTATTTTTGTTTTCTTAATGATGTTAAGCATTTATGCTCACTGGAAACAAACAAAAAGCAGCTGAAAAAGTGCATCAACTCCTCTTTTTCTGAGAAACATGGAGCAGCGCACGCCCAGGCGATGCCAGTCTGTGTGCCGTGATGCCGCACTGTGTTCCCCATGACAGTGGTCCATCATCGTGCACTCGTCATACTCAGAAGTCCAAAGTTCATTCTTCTTTAAAGTAGCCTCTATAACTCTGTTTATTTTATAAATAGTATTCCTTATGGCTGCCACTCTTATTTACCTTTAAATAATTTCTGAAATTTAACCTTTTCAGAATGCATTGTTGAAACAAGATAAAGATTGCCTTTTTTGAATTTTTTAAATTTTGTTTTTAAAAGCATATACCACCTTAGTTCATTCATGTATCCTGGTAAAGCATCTTAATCAGACTTATTTTTAATTACTGAATATTTCTTAGACGTTTTGGGACAGATTTTATGTAATCTTTATAAGTATGATTTCTGAAGAAAAGCAAATGCATTAGTATGTTTGCCTTAAACTTGTAGACTAAACCAAGTATTGTAAAATAAACAGCGATAACAGTGATAGTTTTTAACTCTATGGTCATTGTATCACTCTGGAAAATGTGGAGTAGCTGTAATAAATCTACTCCTGTATTATGCTTTACAGTGCAGGTCTTAGTTTTTCTTTTTTCTCATTTCTTTTGAAATGGCATCTCGAACAAAGTCCACCAATCCCTTTACAAAAGAATGAACTGCTCCTCTGTGTGTACTTCATAGAAGGTGGAATCGGACAGAGGCAGGTTAGTGACAGTTATTCCTGAAATACAGGAGCAGAGTACAGTCTGTTGTGGTTTCCCGGATTCCGCGCCTAGCTCAGCCAATTAAGCATGAGACATAGGCCATTGAGCCACTTAGTAGTTATGCGAGTGGATAGATTGGTATGTAGAGGGAAAGAGGTCTGCTGTAAAGAACAACACTTGTTTGTCTGTGGGGAAAGAAAAGCAGAATACTTGAGATGAAAGTTGGCATACAAATAGGATACTATCGCCAGTAGTTATATTACAAACATTATCGGCCTTTCTAGTGTGAATGAACATTAGACACATTATTGTCATTCCTAGTTTAAAGTTAAGGTTGCGTGGTTGGATTTTTCCACTATCTTTTTCTAATTTTTCTACCATTTGGAGACCGTAGGCATTTGGGCCTGTCACCCCTTGGATGGGTTCCTAGTTTGTTTACATTTTCCTGAACCCTCCTGAGCGCCCGTTCTTGGTCTAATCCCCAGTCGTGATGATTCCACACTTCCTCAGCCGCATGTTGTCTTGCCTCATTCATGAGCTGGTCAGCGTTTCGTCTCTTTAACTGACATGTTCCCCAGTGCTGTTTGAACTGTTGAGTTTCCGTTGCTGGCTGAGTGCGTTTTGTCCTTCACGTAACCTTCGCTGGTAAAAATAAGCCCAtgtgatgtccaccagtggatgaatgctggaccgagagccctagcttctggatccaggtctaggcccttcatctgctgctctgtggcccagggcaggtttgcttgacctctgcctcagttctcgactctaaaggacatactgacctacctcacaggggtgttgtgaggattaataaatgttggtactctgctttggaaatgtgaaaatgctgtgtaaatgttaagaaatactaAGTATAGGGCCAGAAGCTATACAGTGTTTCACTTAACCGTTTGCCATTCTGTATTTACCAAGGTGGTCTTTTCTGGGGAAGGAAGTAGAGTGGAAGGTGCATCCCTTGGCCCCTGGTTTACATTATTAGGGTGCTTATTGTAGGAATGCACTCTAAAAAGTGGGCGTAGAATGAAAGCAGCCGTCcagtggtcctcccttttctgtagtttcacttttcttgcttcaagttacagcagtcacctgaaatctgaaaatactaaatgaaaaactccagaaacaa

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