Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name ZNF708P4
Plot displaying the genomic locations of a retrocopy (in chr19) and its respective parental gene (in chr19). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr19:23742991-23745209  UCSC
Coordinates (T2T) chr19:23882952-23885168  UCSC
Coordinates (hg19) chr19:23925793-23928011  UCSC
Strand -
Parental Sequence XM_017027204.2
Parental seq. overlap 1757 bp
Parental seq. overlap (%) 38.7%
Genomic Region Intragenic (ZNF681)
Retrocopy Summary ZNF708P4, located on chr19:23742991-23745209, is a retrocopy of the parental gene ZNF708. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name ZNF708
Full Name zinc finger protein 708
Also known as KOX8|ZNF15|ZNF15L1
Coordinate chr19:21290385-21329437
Strand -
Gene summary Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription, DNA-templated. Predicted to be located in nucleus. Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes LOC107972443P2
Bonobo Pan paniscus LOC100972001P4
Orangutan Pongo abelii LOC100446243P5
Gibbon Nomascus leucogenys ZNF253P6
Green monkey Chlorocebus sabaeus LOC103234271P3
Baboon Papio anubis LOC103880007P4
Golden snub-nosed monkey Rhinopithecus roxellana LOC115900740P3
Marmoset Callithrix jacchus LOC100400163P4
Mouse lemur Microcebus murinus LOC105863292P3
Gorilla Gorilla gorilla Without Homology
Crab-eating macaque Macaca fascicularis Without Homology
Rhesus Macaca mulatta Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>ZNF708P4
GTAAAAGTGTGGATGAGTGCAAAGTGCAAAAAGGAGGTTATAATGGACTTAACCAATGTTTGCCAACTACCCAGAGCAAAATATTTCAATGTGATAAATATATGAAAATCTTTCATAAATTTTCAAATTTAAATGGACATAAGGTAAGACACACCAGAAAAAAACCTTTTAAATATAAAGAATTTGGCAAATCATTTTGCATATTTTCAAACCTAACTCAACATAAAATAATTTGTACTAGAGTAAATTTCTACAAATGTGAAGACTGTGGAAAAGCCTTTAATGGATCCTCAATCTTTACTAAACATAAAAGAATTCATATTGGAGAGAAATCGTACATATGTGAAGAATGTGGCAAAGCCTGTAACCAGTTCACAAACCTTACTACACATAAGATAATTTATACTAGAGACAAACTCTACAAACGTGAAGAATGTAGCAAAGCCTTTAACCTGTCGTCACACATTACAACACATACAATAATTCATACTGGAGAGAATCCCTACAAACGTGAAGAATGTGACAAAGCCTTTAATCAGTCCTTAACCCTTACTACACATAAGATAATTCATACCAGAGAGAAACTCAATGAATATAAGGAATGTGGCAAAGCTTTCAACCAGTCCTCACACCTTACCAGACATAAGATAATTCATACTGGAGAGAAACCCTACAAATGTGAAGAATGTGGCAAAGCCTTTAACCAGTCCTCACACCTTACCAGACATAAGATAATTCATACTGGAGAGAAGCCCTACAGATGTGAAGAATGTGGCAAAGCCTTTAGGCAGTCCTCACACCTTACTACACATAAGATAATTCATACTGGAGAGAAACCCTACAAATGTGAAGAATGTGGCAAAGCTTTTAACAAGTCCTCACACCTTACTAGACATAAGAGCATTCATACTGGAGAAAAACCCTACCAGTGTGAAAAATGTGGCAAAGCTTCTAACCAATCCTCAAACCTTACTGAACATAAGAATATTCATACTGAAGAGAAACCATACAAATGTGAAGAATGTGGGAAAGCCTTTAACCAGTTCTCAAACCTTACTACACATAAAAGAATTCATACTGGAGAGAAACCCTACAAATGTGAAGAATGTGGCAAAGCTTTTAACCAGTCCTCAATCCTTACTACACATAAGAGAATTCATACTGGAGAGAAATCCTACAAATGTGAAGAATGTGGCAAAGCTTTCTATCGATCCTCAAAACTTACTGAACATAAGAAAATTCATACTGGAGAGAAACCCTACACATGTGAAGAATGTGGCAAAGCCTTTAACCATTCCTCACATCTTGCTACACATAAGGTAATTCATACTGGAGAGAAACCCTACCAATGTGAAGAATGTGGTAAAGCCTTTAACCAGTCCTCACACCTTACTAGACATAAGAGAATTCATACTGGAGAGAAACCCTACCAATGTGAAAAATGTGGCAAAGCTTTTAACCAGTCCTCAAACCTTACTGGACATAAGAAAATTCATACTGGTGAGAAACTCTACAAACCTAAAAGATGTAACAGTGATTTTGAAAACACTTCAAAGTTTTCTAAACATAAAAGAAATTATGCTGGTGAGAAATCTTAGAAATGTGAAGAATGTAACAAAACCTTTAAAAGTTGTCACACTTGATTGTGCATAAGATAATTCATACTAAAAAAAAACCTACAAGTGTGAAGAATGTGGCAAAACTTTTAACCAATGCTCACACCTTATTGCACAGGAAAGCATTTGTACTAGAAAAAAATTTCAAATATACAGAATGTGAAAAAGCCATTAATATCTGTTCACATCTTACTCAACATCAGAGATTTCATACTTAATAAAAGCATTATACATGCAATTACTGTCAAAAATCTTTCAGAAAATATAAGCCTCTAAAGTGAAGAGTATTCATTTTGAAGACACACATTATGAACATAAGGAGGGTTGTGGTACCTTTACTTGTATCACAGATCTCATTGTACACATTTTGTGCTAGAGGAAAACCATGGAGCAGTTGCTTAAACTTTGTGCAACATAAGGAAATTTATATTGGAGAAAAACCCTGCAAATGTAATAAATTTGGGAAAACATTTTTTCAAAAACGACAGCTTAGAAAACACTAGAGGGTTCATACTAAAATCTATTTTTGCAGATGCAGTAAATATGAAAAAATATTTAATCCAAAATTCTATGTAAATATCAGATAATTCACAGTAGAAATAG
>XM_017027204.2
TCTGGAAGCCTAGAAATGGGACCATTGACATTTATGGATGTGGCCATAGAATTCTCTCTGGAGGAGTGGCAGTGCCTGGACACAGCACAGCAGAATTTATATAGGAATGTCATGTTAGAGAATTATAGAAACCTGGTATTCCTGGGTATTGCTGTGTCTAATTTAGACCTGATCACCTGTCTGGAGCAAGGAAAAGAGCCCTGGAATATGAAGAGACACGAGATGGCAGCCAAACCCCCAGCTATGTGTTCTCATTTTGCCAAAGACCTTAGGCCAGAGCAATATATAAAAAATTCTTTCCAACAAGTGATACTGAGAAGATATGGAAAATGTGGATATCAGAAAGGCTGTAAAAGTGTGGATGAGCATAAGTTGCACAAAGGAGGTCACAAGGGACTTAACCGGTGTGTGACAACTACCCAGAGCAAAATAGTTCAGTGTGACAAATACGTGAAAGTCTTTCATAAATATTCAAATGCAAAGAGACATAAGATAAGACATACTGGAAAAAATCCTTTCAAATGTAAAGAATGTGGCAAATCATTTTGCATGCTTTCACAACTAACTCAACATGAGATAATTCATACTGGAGAAAAACCCTACAAATGTGAAGAATGTGGCAAAGCTTTTAAAAAGTCCTCAAACCTTACGAATCATAAGATAATTCATACTGGAGAGAAACCCTACAAATGTGAAGAATGTGGAAAAGCTTTTAACCAGTCCTCAACTCTTACTAGACATAAGATAATTCATACTGGAGAGAAACTCTACAAATGTGAAGAATGTGGCAAAGCTTTTAACCGGTCCTCAAACCTTACTAAACATAAGATAGTTCATACTGGAGAGAAACCCTACAAATGTGAAGAATGTGGCAAAGCTTTTAAACAGTCCTCAAACCTTACTAATCACAAGAAAATTCATACTGGAGAGAAACCCTACAAATGTGGAGAATGTGGCAAAGCCTTTACCCTATCTTCACACCTTACTACACATAAGAGGATTCATACTGGTGAGAAACCCTACAAATGTGAAGAATGTGGCAAAGCTTTTAGTGTATTTTCAACCCTTACTAAACATAAGATAATTCATACTGAAGAGAAACCCTACAAATGTGAAGAATGTGGCAAAGCTTTTAACCGGTCCTCACACCTTACTAATCATAAGGTAATTCATACTGGAGAGAAACCCTACAAATGTGAAGAATGTGGTAAAGCCTTTACCAAGTCCTCAACTCTTACTTATCATAAGGTAATTCATACTGGAAAGAAACCCTACAAATGTGAAGAATGTGGTAAAGCCTTTAGTATATTCTCAATCCTTACTAAACATAAAGTAATTCATACTGAAGACAAACCCTACAAATGTGAAGAATGTGGCAAAACTTTTAACTACTCCTCAAATTTTACTAATCATAAAAAAATTCATACTGGAGAGAAACCCTATAAGTGTGAAGAATGTGGCAAAAGCTTTATTCTGTCCTCTCATCTTACTACACATAAGATAATTCATACTGGAGAGAAACCCTACAAATGTAAAGAATGTGGCAAAGCTTTTAACCAGTCCTCAACCCTTATGAAACATAAGATAATTCATACTGGAGAGAAACCCTACAAATGTGAAGAATGTGGCAAAGCCTTTAACCAGTCCCCAAACCTTACTAAACATAAGAGAATTCATACCAAAGAGAAACCCTACAAATCTGGAAGACATCACAGTAATTCTGACAACACCTCAAACTTTTCTAAACATAAAATAAATCATACTGGTGAGGAACTTTAAAAATGCGAAAAATGTGACAAAATCTTTAAATGATTGTCACACTTGATTGTAGGTAAGATAATTCTTACTAGAAAAACTCTTACAAGTGTGAAGAATGTGGCAAAATTTTTAATGAATACTCACACCTTATTGCCAGGAAAGCATTTATACTTGAGAAAAATTGTACCAATATAAAGACTGTGAAAAAGCCATTAATGTCTGCTCACATCTTACTCAACATCAGAGAGTACTTAAAAAAAGTATTATAAATTTAATTACTGTCAAAAAGTATTTCAGAAAATATAAGCTTTTAAAGTATTTATTTTGAAGACAAACATTACAAATAAAAGAGGATTGTAATACCTTTATTTGTATCACAGATCTTATTGTACACATTTTGTACTAGAGAAAACCCTGAAGCAGTTACTTAAACTTTGTTCAACATCAGGGAATTCAGATTGGAGAAAAACCCTGCAAATGTAATAAATTTGAAAAAAAAGTTTTCCAAAACTACAACTTAGACAACACCAGAGGGTTCATACTGAGATATATTTTTGCAGATGCAGTATATATTTAAAACATTTAATCCAAAATAAGTCTATGTAAATATCAGAGAATTCACAGTGGAAATATCTAAGGTAGggccgggcatggtggctcacgcctgtaatgccagcactttgggaggctgaggtgggcagatcatgaggtcaacagattgagaccatcctggtcaacatggtaaaaccctgtctctactaaaaatacaaaaattagctgggcgtggcggcacgtgcctgtagtctcagctacttgggacgctgaggcaggaaaatccgttgaacccaggaggcagaggttgtagtgagccgagattgcaccactgcactccagccgggtgacagagtgagactccatctcaaaaacaaacaaaCTAAGGTATGGATGCTTCAGACATTACACTATATCAAAGTGCTGACTGTTAAAAATGATCCCAAACTAACGGTAGATAAATTTATTTGTACATAACTTTAAAAGGAGTAGAAGATTTTTTGGAAGTTTGTAATTACATTCAAAGTATACtttttttgtttgtttgttttccttgagacagagtctctctctgtcgtccaggctggagtgcagtggcacaatctcagctcgctgcaacctctgcctcctgggttcaagcaattctcctgcctcagcctactgagtagctgagattacaggtgcacaccaccacgtccggctgacttttgtatttttagtagggacggggtttcaccatattggtcagggtagtcttgaactcctgacctcatgctctgcccagcttggcttcccaaagtgctgtgattacaggcttaagccacagcgcccggccCAAAGTGTTCTTTTTTCCTTGAAAAGAAGTACAGATTTTTTAAAAAGCTAATATTGCTGTGATTCAACTCTCTAGTTACTTGATGCTATTTCTTCATTTCTATTGTATTCACATGTGAAAGCATGTGATCAGTTGTCACGGCATCAAAGATAGGAGAGTTTCTTTTTTTTTAGGTGGGCATTATTTATGACCTTTTCTTTGGAAGAGTAAGGACATTAAAATGTAACATGCATGATGAAAATCTAAGTGGAGATGGTATTTGTGGTTAATTATGATATTGAGTGGTGCATGAGGTAGGTGTTTAGAGTAATATTCTTTTGCATTATAGTAAGAACATTTAAGTTTTGTTAAAATTAAAAAATTAGTACGTTATTTTACTATTTGTACTTTTATGTAATAAAATGCAGTACATTTTTAAATTTTCAGATGATGTGTGAACTTGTTTCATTATACATTTTTAACATGTTAATACTATTGTGCATTCAATGAAGCATTATTATGCCACTAACTGAAACCTATCCCATTTACTCAAAGGTGTAGGTAAATGATAGTAAGAATATACTATTTGGTAATGTAATCAACTAACATCTCTGGTAATCTCCTTTGCCAGTGGCTTTCAACTGCAAATAAGTTTAAAAAATACTGTTTCCGTAGGTTAAATTTTTATTATTTTTTCTTGTTGAAATCTGTTTAAtttttttttttttttttgagacagtgtctcgctgtgtcccccaggctggagtgcagtggcacgatctcggctcactgcaagctccgcctcccacattcacgccattctccttcctcagtgtcctgagtagctgggactacaggcgcccgccaacacgcccagctaattttttgtatttttagtagagacggggtttcaccgtgttagccaggaggggctcgatctcctgacctcatgatccgcccatctcggccttccaaagtgctgggattacaggcgtgagccactgcgcctggccTAGATTTTTATACAACGTGTAGCAAATACAAAATTTGCTAGAGAATATATTTTAGAAATCAAAATTTTAGGAGTTCTAATGGTAAGTAAAGAATTTTAAATTTACTTTTCTGTAATGTAGTGTAACTTAATTTCTATGCAGAATCTTCTACTTTAAGAGTGAATGTTAAACATGGCAAAATAATAAAGTGACCTCTGTGAATTTGAAA

Publications

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