Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

Advanced Search

Summary

Retrocopy Name HPCAL4P2
Plot displaying the genomic locations of a retrocopy (in chr2) and its respective parental gene (in chr1). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr2:10419769-10420015  UCSC
Coordinates (T2T) chr2:10449368-10449614  UCSC
Coordinates (hg19) chr2:10559895-10560141  UCSC
Strand +
Parental Sequence NM_016257.4
Parental seq. overlap 209 bp
Parental seq. overlap (%) 4.5%
Genomic Region Intragenic (HPCAL1)
Retrocopy Summary HPCAL4P2, located on chr2:10419769-10420015, is a retrocopy of the parental gene HPCAL4. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name HPCAL4
Full Name hippocalcin like 4
Also known as HLP4
Coordinate chr1:39678648-39691433
Strand -
Gene summary The protein encoded by this gene is highly similar to human hippocalcin protein and hippocalcin like-1 protein. It also has similarity to rat neural visinin-like Ca2+-binding protein-type 1 and 2 proteins. This encoded protein may be involved in the calcium-dependent regulation of rhodopsin phosphorylation. The transcript of this gene has multiple polyadenylation sites. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2013]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes HPCAL4P2
Bonobo Pan paniscus HPCAL4P2
Gorilla Gorilla gorilla HPCAL4P2
Orangutan Pongo abelii HPCAL4P2
Gibbon Nomascus leucogenys HPCAL4P2
Green monkey Chlorocebus sabaeus HPCAL4P1
Crab-eating macaque Macaca fascicularis HPCAL4P2
Rhesus Macaca mulatta HPCAL4P2
Baboon Papio anubis HPCAL4P2
Golden snub-nosed monkey Rhinopithecus roxellana HPCAL4P2
Marmoset Callithrix jacchus HPCAL4P2
Cow Bos taurus HPCAL4P2
Horse Equus caballus HPCAL4P2
Dog Canis familiaris HPCAL4P2
Sloth Choloepus didactylus HPCAL4P2
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>HPCAL4P2
GAACAGCAAGCTGCGGCCCGAGGTGCTGCAGGACCTGCGGGAGAACACGGAGTTCACCGACCACGAGCTGCAGGAGTGGTACAAGGGCTTCCTCAAGGACTGCCCCACCGGCCACCTGACCGTGGACGAGTTCAAGAAGATCTACGCCAACTTCTTCCCCTACGGCGACGCTTCCAAGTTCGCCGAGCACGTCTTCCGCACCTTCGACACCAACGGCGACGGCACCATCGACTTCCGGGAGTTCATC
>NM_016257.4
GATACAAGAGCTGGAAGGCGGCTCCGGCGCAGACCTTGGAGAGCACAGCTGCCGGCCCGCGAGCCAGCCTCGGTTCCCGCGGCCCGCCGAGGCTCGGAGCCATCCAGCGACCCGGCGACCGGCCTCAGGCCCCGCCATGGGGAAGACCAACAGCAAGCTGGCCCCCGAGGTGCTGGAGGACCTTGTTCAGAACACTGAGTTCAGCGAGCAGGAGCTGAAGCAGTGGTACAAGGGCTTCCTGAAGGACTGCCCCAGCGGCATCCTCAACCTGGAGGAGTTTCAGCAGCTCTACATCAAGTTCTTCCCCTACGGCGACGCCTCCAAGTTCGCGCAGCACGCTTTCCGCACCTTCGACAAGAACGGCGACGGCACCATCGACTTCCGGGAGTTCATCTGCGCCCTGTCGGTCACCTCCCGCGGCAGCTTCGAGCAGAAGCTCAACTGGGCCTTTGAGATGTACGACCTGGACGGCGACGGGCGCATCACGCGCCTGGAGATGCTGGAGATCATCGAGGCAATCTACAAGATGGTGGGCACCGTGATCATGATGCGCATGAACCAGGACGGGCTCACGCCCCAGCAGCGTGTGGACAAGATCTTCAAGAAGATGGACCAGGATAAGGACGACCAGATTACATTGGAGGAGTTCAAGGAGGCAGCCAAGAGTGACCCATCCATTGTGTTGCTGCTGCAGTGTGACATGCAGAAGTAGAAGCTGGTGAGGGGCAGGGTCCCTGGCCAGAAGGGGCATGGCCACCTCCCAACCTGATGACCTCTCTGGCTGGCCTCCCAGGAGGAGGGACACTCCAGCCCCCCTCTCTGGCCCACCCAGTCCTCTGCCCAAGCCCTTCCTCCCCTCCATCAAGATCTTTGAGGGACCACCTCACCCTGCAAAAGAGACAGGTCCTCCAGTACCCTGTCTTCTAGCCCCACCTCCCACTTGGCCAGAACCAATGTCCATTGGGCATAGGGGAGTTGGCTTTTGCCCCAGGAGGTGAGGTTAAGGAGTTGGGGGCCTGGGGTTCTGGTTAGGAATTCTCTTGATCCTGGGATTATGCTTTATAGGATGTGGTCCCACAGGCCTGTCACAGGGCCAAATTGGGTCTGTCCATTCCTGAGGCTCCAGATCCCATAAAGGGGGTCTCTTCCCCATCCCTTCTACTCTACCTGGCCCTTCCAGCCCCAGCCTTTGGAGCGTTCATTCAGtcctttcttcagctaatgattactgagcacctgtttggtgctaaggatatggtcatttacaagacacatcttgtgccctctggaagctcatagggttgtgaggcaaacTTCCAGCCGTCAGGGTCTCAGCTAAGCAGAAGGTGCTGGAAGGCTGGTTAGTCTGGGAGGAGCTATTTCATCTTCCAGCTCAGCTCCACACAAAGCTGCAGAAGGACGAAATGAAAAGCATTTGGAAGTTTAGGAGCCACGTGAGTGAAAGTTTTAAGAAAAATGAAATTTATGTCATACTTATTTTTTTAGTACCCTTTAAAGGAGCTACAGTCATTTTATTATTTCAGGAGGTTAAAATATACTCTATATTACTTGGTTTCTTATAAAATGATTAAATGAATAGAGAAAATATTAATTTTCAAGGGGAAAAAACCTGAGAAGAAAGGGAGAAAAGACCATGAAATTTACCAGATAACACTTTTTAAGACTAAGTCCTGAGCTGCCACTCTCAGCAGTTTTTGCTGCTTCAGCTCTTCCTTTTTATTACCTTTTTCAATTCAACAAGCAACTTTCTGCTACATACTTACTCCGGTTGGGTGCTGACTTCAGGGACAGGAAAAAGCAAGGTTTGCAAAGAGTGAAACTAGTGTATATTCCGTATCTTGGTAGTTCGTTTCTGGATTGGGTTTAGTTTCAGAACTGGACTTGTTCCTTCACTGCCACAGAATCAGAAAGAGCTAGAAGAAAAGGCTCACCTGGCCACTGTTTAGGCACCCAGACATAATTTATGGACGAAATGCCTAAAAATGTGCCAGGCATGCTCTGTTTGAGAGGCTTTTTCTAACCCCAAATCTTAGATCTGCCAGGTAGTTCAACATCTTCCAAGTGTGCTGGTTCTGCTTTCCAATGCCTGCTTCCCAATTTTGGATCCATGAGCTATACAGCTGCATGCTTTGACTGCCGGAAAAATTAATCTTGCTTCTTCATCAGGTCTTTCTCCTGTACTTGTGATCAGAAATTACCTTTGACGTGCAGTGACAGTTGATTTCCTCTTGAACTGCCGGTGAAAACAGTCTAGTACACAGGTGCTGTCAGCCCAGGGTGGGAGCAGGAAATGATTGCTGAGCCCGGGGCAGGGGAATTGCATCTGCAGGAAAGAGATGCAGCATGCTCCTCACTCCTGAGTGCCCACCTGTCCTGCTTCTCTGCAGGTGAAAACTCTGGGGGATGCTGATCAATAGAGCTTGGTCCCAAGCTCTACTGGGCCCTTGGAGGTAGCAAGGCCACTGGGTTGCTATCCTCTTGCTGGGGATAGCAACCACTGGTTTGCAACCACTGGGTTGCTATCCTTTTGCTATCCTCTTGCTCATGACCAGCCATATGGTGAGGCTGGGGAGTTCACATCCTCAGGCAGGAACTAGCAGTTGTTTATCCAGCAATGCCTCAAGGATGTTGCATTGCTCCCAGGAACTGGCTATTAGGTATGTCTTGTGCGGTCAGTCAGCATCACAGACACATAGATGCTCACCAGCCTGGCTTAGCTGGGACCTAAATCTTCTGGTGAAAAGCTTTTCACTAAGTGAGGTTCCTTCCCTGCAAATGCTGAATCTAGCCTAATTCGCAACCACacagaatttcatggctttcaaaggcttgccatgtgccccatctcattctatactcacatcccatggaggtgaggattttcacttcttttctctagacttggaagctgagattcagagaggaagcatcccttgtgcaagatcacatagtcaggaggtgacacagggctaagacttgaaccaaggCTCTAAGAGGATTTCTTCTTTTCAGAGTCTCTTCCCTGTCCATTTCTGTGACTAAGCTGTGCAGAGGTTGACAGCAGGGCAAGTTACATTGATATTCATCCTTTATAGGCTTCCTGCTAAAAAGCTTCTGAGATTGTGGTCTTCCAAAAAAAATAGGAGCTTGGTTGAAGTCCCCACATTTTCAAGCACTCAGTGTTCTGCCTCTGGCAGCTGTGCTAACAGCTCAGTGCTGTCCTGGGAGTCCTCTGACTCAGAACCCTCGAAGCATCCTGCATTGTCTTTACCCACCATCATCTTCACTAAGAGAAACATGCCTACCCATGAAGGCGTGTTTGATTACTCCAGGCTTCTGGACACACATACCCATGGGTGATTTTTGCTCCTCAGGCCCAATATTCTCAGACAGCCCAGCAGTGTGAACACACAATGCCAGGCCAGGAACTGGGACCACCATCTTGCTGATGGAAGGAACAACAGGTGGCCCAGGACATGCTCCTGCATACTCCTGGGTGTCCCAGGGACTGTGTGCTCAGGAGCACTGTGGTAGAGCACTGGCCCTGCCTTGAGAAGAGACACAGGTCTCCCGTCCCTGCACCAGCTGAGAGAGACTTGCCGCAAAGCACAAGGCTGGCAGAGATTTATGTATGACTTGCACAGACACAAAAATATACAGACAATCAAAACATTGATATATTCAAACTCTCCTTTAAATTCCAATCTTATTGCAACAACTCTGTGAATTGCAAGGTCCCAGAATCTGCCTTCTCACATACTCTACCCTCATTCATCCTTTTGGGCTAATTGATGAGCATCTTATTTCTTATCTCTAAAAATTATCAGCAAAGGCTACTTCAGATGGCCACTTTAGTCCTTTCAGCTGTAGTCAGGATTATTTAACTTACCTGTATATCAAAAGTGAAGAAAAAGTTAGTTCATAAGTAAAGGCACTAAATCCTTTCCTGACAATGGCAGAGTCTCTAGAGGTAGAAATTTGCCTTGCTGCAGAGAGAGAAGGAATGGCGTGGGATGGGGGAAAGAAAAGAAAGAGAAGAAGCTGGGGTCTCCAGGCAGGGTAGTAAGCTGACACTAAATATTTTTTACACAAAAatgtattgaagcaacaaatatttcctgaagatccaccctgggtgaggctttgagctgactttagagatcactgtggggtcaagaATGTCTTACATGTTTTATTCATCATTCTTGAAAAAAGAAATAATTCAAACCTTGGAATTAAAAAGTCAGAAAAATATGGGATTTTCTTTCTGGAATTTTCGAGGTTTTCTTTTTACCTTTGCCAGAGTGTGGGGGCAGGACTGGGCCTGCCAGGGTGTATAGCCCTTCCTGCTTGGTGGAGGCCAGTCAGGCCCAGGGCCTTCTAAGCAGCAGTAGAAAGGAGGCTTGGGGAAGTGGGGGGTCTGGGTAGCAGGGGAAGGAGGCCAGTTCCAGTGTAGCCCCCTATCCCCTCCAGATGTGCTGCTTCTGGCTGTGCACTCAGTGACTGCCCTCACTGCTCAACCCTGTGCTGTGTGGTGTGTTTCTTTCCCCACTGACAGTGAATAAAAGGTGCAACTGTG

Publications

PMID - Link Title