Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name HNRNPDLP2
Plot displaying the genomic locations of a retrocopy (in chr2) and its respective parental gene (in chr4). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr2:158424723-158426032  UCSC
Coordinates (T2T) chr2:158881495-158882805  UCSC
Coordinates (hg19) chr2:159281235-159282544  UCSC
Strand +
Parental Sequence NM_031372.4
Parental seq. overlap 1141 bp
Parental seq. overlap (%) 25.9%
Genomic Region Intragenic (CCDC148)
Retrocopy Summary HNRNPDLP2, located on chr2:158424723-158426032, is a retrocopy of the parental gene HNRNPDL. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name HNRNPDL
Full Name heterogeneous nuclear ribonucleoprotein D like
Also known as HNRNP|HNRPDL|JKTBP|JKTBP2|LGMD1G|LGMDD3|laAUF1
Coordinate chr4:82422564-82430462
Strand -
Gene summary This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has two RRM domains that bind to RNAs. Three alternatively spliced transcript variants have been described for this gene. One of the variants is probably not translated because the transcript is a candidate for nonsense-mediated mRNA decay. The protein isoforms encoded by this gene are similar to its family member HNRPD. [provided by RefSeq, May 2011]

Homology

Species Scientific Name Retrocopy
Gibbon Nomascus leucogenys HNRNPDLP2
Green monkey Chlorocebus sabaeus HNRNPDLP1
Crab-eating macaque Macaca fascicularis HNRNPDLP1
Rhesus Macaca mulatta HNRNPDLP1
Chimpanzee Pan troglodytes Without Homology
Bonobo Pan paniscus Without Homology
Gorilla Gorilla gorilla Without Homology
Orangutan Pongo abelii Without Homology
Baboon Papio anubis Without Homology
Golden snub-nosed monkey Rhinopithecus roxellana Without Homology
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>HNRNPDLP2
aGGGAAAGAATCCCCCAAAAAGGGTTTTGTGGGTGGATTGAGCCCAGAAACTTCTGAAAAACAAATTAAAGAATATATTGGAGCCTTTGGAAAGTTTGAAAATATTGAAATTCCCATGGATACAAAAACAAATAAAAGAAGATTTTGTTTTCTCACATATATAGATGAAGAGCCAGTAACGAAATTGTTAGACAGCAGATTATTATCAAATTGGTTCTGGGAAGTGTTAAATCAAAGTTGCACAACCCAAAGAGATATAGAAGCTGCAACACCAAAACAAAAAGGAAGAACAGGTGCTGCAACCAGTGAATGAGGGGGCCCTAGGGGGTCGTGACCAAGGTCAAGGCATAATTGGAATCAATGATCTAGTGACTACTATGATCGCGGATATGGGAATTACAATAGTGCCTATGGTGGTGATCAAAACTGTAGTGGCTATGGCAGATATGATCATGCTGGGTATAACTATAGGAACCATGACTATGCACAGGTGTATGCAGACTATAGTGGCCAAGAGAGCACTTATGGCAAGGCATCTCCAGGGGGTCGCAATCACCAAAACAATCACCAGCCATACTAAAGGAGGACATTGGAGAAAACAGGAGATGATGCTAAAATAACCCATCTTGCAGGATGACATTGAAGACTGGTCTTTTGTTGATCTAAGATGATTATTTTGTAAAAGACTTTCTAGTGTACAAGACACAATTGTGTCTAACTGTATATAGCTGCCAATTCATGTTCTTTGTTTTTACTTTGTCCTTTGCTATCTGTTATGACTCAATGTGGATTTGTGTTTATACACATTTTATTTGTATGATTTTATATTAAACCTCAAATAAATGCTTCCTTATGTGATTATTTTTCTGTGTCAGGTACCACATGGCTCCATAAAAATATAATTTTAAATAAGCAATAATTAAGGCACAGTTTGTTGTGCGGAGAGAATTGATCCATAGGGAGAAACTGTGGTCCTTTATAAATAGCCAGCCACAGTGACACCCTGTTTCCCAATATGTAGATATATTCCATGCTCTTAAGGCTTCATCTGTCTGTTACCTGAAGTTTCCACCACATCTTTGGATGATGTTTTTCCCCTCTGGATATCTGAAGACACTGTCCTGAGACAAAGTCACAGTGTTGTGATCACTGGAAGCTTTCTAGTAGACCATGTGTCCTCTGGATTGTAACATAATGATTATTAGTAACTCCTTTTGCTTTGTTCTTGTCTCTGGAAAGCCATCTTTGAATTGCTAATTACTTCTTTGACTTTAGAGCTAATCAGTGGTCTGCTAGAAAAAGCTTT
>NM_031372.4
AACAAAGAAGCGAACGCGGGAGCAGGGTGCGCGAGAGCGCGCCCTCCGCAGACAGGTTGAGCGAGCGGGAGAGGCCCGGGGCACGTGCAGAAAGGAGCCCCGCGAGTGGCGCGCCGGGGATGTGAGTGCCCCTTGCCCTCTACTGAATCCAGCCCCCTCCCCGCCCACCGCCTCCGCCTTTGCATAGATACAGTCATCTGGCCAGCCCCCGCCCCTCCTCCCGGCGTCAGCCCGCCAGAGGCCGCGCGGGGCCCGGGCTTCGGCCGATCAGCCCGGGAGGCCCCGCCGCGCCCCCTTGGCCCGCGCGCCCGTGGTCACAGTGGAAGAGGCGCCCGCGCTGCGCTGCCCGGAGGAGCCGTCGCGCGCCCGCTTCCTGTTCGGCTGGTTCCTGCCAGCTCGAGGACAAAACAcgcgtgcgcgcggcgggcgagcgcgctcgccgcCTCAGTCGCCAGCGCCGGGCGCAGTCCGCCTTTTTCCGGAGCAGACTGGCCGCGGTGCTAGTCGGTAGCAGCGGCCGCCGCAGCGGCTCCGCACTGGCGAACCGAGGGCAGAAAAAGGCGGGGTTGACGGCTTTTTGGTAGGAGTGGGCTGGACCGGACGCCAGAGACAAAGGCTCCCAAGGCAAGAGGGACTGTGGCCCTGCGTCGGCTCTGCTCGGGACTGCTGACCCCAGGAATTTACGCCCCTTCGTTTTTCTCTTCTGATTCTTCTCTTCTCCCAAGCCCGCGTCCCCTCACGCGTGGCCTCTCTCCTTGCCGGGAGGGCCGCGATGGAGGTCCCGCCCAGGCTTTCCCATGTGCCGCCGCCATTGTTCCCCTCCGCTCCCGCTACTTTAGCCTCCCGCAGCCTCTCCCATTGGCGGCCGCGGCCGCCGCGGCAGCTAGCCCCGCTCCTCCCTTCGCTCGCTCCCAGCTCCGCCCGGCAGGGGGCGCGCCGGGCCCAGCGCCACGTCACCGCCCAGCAGCCCTCCCGATTGGCGGGCGGGGCGGCTATAAAGGGAGGGCGCAGGCGGCGCCCGGATCTCTTCCGCCGCCATTTTAAATCCAGCTCCATACAACGCTCCGCCGCCGCTGCTGCCGCGACCCGGACTGCGCGCCAGCACCCCCCTGCCGACAGCTCCGTCACTATGGAGGATATGAACGAGTACAGCAATATAGAGGAATTCGCAGAGGGATCCAAGATCAACGCGAGCAAGAATCAGCAGGATGACGGTAAAATGTTTATTGGAGGCTTGAGCTGGGATACAAGCAAAAAAGATCTGACAGAGTACTTGTCTCGATTTGGGGAAGTTGTAGACTGCACAATTAAAACAGATCCAGTCACTGGGAGATCAAGAGGATTTGGATTTGTGCTTTTCAAAGATGCTGCTAGTGTTGATAAGGTTTTGGAACTGAAAGAACACAAACTGGATGGCAAATTGATAGATCCCAAAAGGGCCAAAGCTTTAAAAGGGAAAGAACCTCCCAAAAAGGTTTTTGTGGGTGGATTGAGCCCGGATACTTCTGAAGAACAAATTAAAGAATATTTTGGAGCCTTTGGAGAGATTGAAAATATTGAACTTCCCATGGATACAAAAACAAATGAAAGAAGAGGATTTTGTTTTATCACATATACTGATGAAGAGCCAGTAAAAAAATTGTTAGAAAGCAGATACCATCAAATTGGTTCTGGGAAGTGTGAAATCAAAGTTGCACAACCCAAAGAGGTATATAGGCAGCAACAGCAACAACAAAAAGGTGGAAGAGGTGCTGCAGCTGGTGGACGAGGTGGTACGAGGGGTCGTGGCCGAGGTCAGGGCCAAAACTGGAACCAAGGATTTAATAACTATTATGATCAAGGATATGGAAATTACAATAGTGCCTATGGTGGTGATCAAAACTATAGTGGCTATGGCGGATATGATTATACTGGGTATAACTATGGGAACTATGGATATGGACAGGGATATGCAGACTACAGTGGCCAACAGAGCACTTATGGCAAGGCATCTCGAGGGGGTGGCAATCACCAAAACAATTACCAGCCATACTAAAGGAGAACATTGGAGAAAACAGGAGGAGATGTTAAAGTAACCCATCTTGCAGGACGACATTGAAGATTGGTCTTCTGTTGATCTAAGATGATTATTTTGTAAAAGACTTTCTAGTGTACAAGACACCATTGTGTCCAACTGTATATAGCTGCCAATTAGTTTTCTTTGTTTTTACTTTGTCCTTTGCTATCTGTGTTATGACTCAATGTGGATTTGTTTATACACATTTTATTTGTATCATTTCATGTTAAACCTCAAATAAATGCTTCCTTATGTGATTGCTTTTCTGCGTCAGGTACTACATAGCTCTGTAAAAAATGTAATTTAAAATAAGCAATAATTAAGGCACAGTTGATTTTGTAGAGTATTGGTCCATACAGAGAAACTGTGGTCCTTTATAAATAGCCAGCCAGCGTCACCCTCTTCTCCAATTTGTAGGTGTATTTTATGCTCTTAAGGCTTCATCTTCTCCCTGTAACTGAGATTTCTACCACACCTTTGAACAATGTTCTTTCCCTTCTGGTTATCTGAAGACTGTCCTGAAAGGAAGACATAAGTGTTGTGATTAGTAGAAGCTTTCTAGTAGACCATATTTCTTCTGGATTGTAATAAAATTGTTAGTAGCTCCTTTTACTTTGTTCCTGTCTCTGGAAAGCCATTTTTGAATTGCTGATTACTTTGGCTTTAATCAGTGGTCACCTAGAAAAAGCTTTGTAATCATAACACAATGAGTAATTCTTGATAAAAGTTCAGATACAAAAGGAGCACTGTAAAACTGGTAGGAGCTATGGTTTAAGAGCATTGGAAGTAGTTACAACTCAAGGATTTTGGTAGAAAGGTATGAGTTTGGTCGAAAAATTAAAATAGTGGCAAAATAAGATTTAGTTGTGTTTTCTCAGAGCCGCCACAAGATTGAACAAAATGTTTTCTGTTTGGGCATCCTGAGGAAGTTGTATTAGCTGTTAATGCTCTGTGAGTTTAGAAAAAGTCTTGATAGTAAATCTAGTTTTTGACACAGTGCATGAACTAAGTAGTTAAATATTTACATATTCAGAAAGGAATAGTGGAAAAGGTATCTTGGTTATGACAAAGTCATTACAAATGTGACTAAGTCATTACAAATGTGACTGAGTCATTACAGTGGACCCTCTGGGTGCATTGAAAAGAATCCGTTTTATATCCAGGTTTCAGAGGACCTGGAATAATAAAAAGCTTTGGATTTTGCATTCAGTGTAGTTGGATTTTGGGACCTTGGCCTCAGTGTTATTTACTGGGATTGGCATACGTGTTCACAGGCAGAGTAGTTGATCTCACACAACGGGTGATCTCACAAAACTGGTAAGTTTCTTATGCTCATGAGCCCTCCCTTTTTTTTTTTAATTTGGTGCCTGCAACTTTCTTAACAATGATTCTACTTCCTGGGCTATCACATTATAATGCTCTTGGCCTCTTTTTTGCTGCTGTTTTGCTATTCTTAAACTTAGGCCAAGTACCAATGTTGGCTGTTAGAAGGGATTCTGTTCATTCAACATGCAACTTTAGGGAATGGAAGTAAGTTCATTTTTAAGTTGTGTTGTCAGTAGGTGCGGTGTCTAGGGTAGTGAATCCTGTAAGTTCAAATTTATGATTAGGTGACGAGTTGACATTGAGATTGTCCTTTTCCCTGATCAAAAAATGAATAAAGCCTTTTTAAACAAAATCCAAACTTTTAATCAAGTCTTGATATGTATGACTGAGAAAAAATACACTACATCTAGAGATGATTGAGATGTTTTGCAAAGAATTGAAGGGGGAGTGAGAATTGGTTTTTCTTGCAGGGGCTTTGAACTCTAGATTTGGGCTTTGAACTCTAGATTTAATTCAGATTTCAGGGTCTATCAGTTCACCAACTGATGCAAATTTGAACAGATACTCTAAGGCTAAGTGTCCTAGGTTGGATGAACTGAAGCTACTATCAAGATCTCGTTCCCAAGGATTAATTTAGAACAAAGTAATTGGACAAGTTTATTGGGGAGGGGATAGAAATGAATTCTAAAGTACCTATAACAAATACTCTGTGTATGTTTTTTACATCGTATTTGCCTTTTACATTGTTTAGACCAAATTCTGTGTGATGTTATCCTCGGGAAGAGGATAGAAATTAATTCTAAAGTACCTATAACAAATGCTCGGTTTGTATATGTTTTTATACATCGTATTTGCCTTTTGCATTGTTCAGACCAAATTCTGTGTGATGTTATCCTAACAAAACACCTTAGTAATTTCTTTGGTTAACATGTTAATCTGTAATCTCACTTTTATAAGATGAGGACTATTAAAATGAGATGTCTGTTGGGA

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