Retrocopy Name | TUBA3CP16 |
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Species | Homo sapiens | |
Coordinates (hg38) | chr2:219250390-219251315 UCSC | |
Coordinates (T2T) | chr2:219735157-219736082 UCSC | |
Coordinates (hg19) | chr2:220115112-220116037 UCSC | |
Strand | - | |
Parental Sequence | NM_006001.3 | |
Parental seq. overlap | 802 bp | |
Parental seq. overlap (%) | 52.7% | |
Genomic Region |
Intergenic |
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Retrocopy Summary | TUBA3CP16, located on chr2:219250390-219251315, is a retrocopy of the parental gene TUBA3C. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes. |
Gene Name | TUBA3C |
Full Name | tubulin alpha 3c |
Also known as | TUBA2|bA408E5.3 |
Coordinate | chr13:19173772-19181824 |
Strand | - |
Gene summary | Microtubules of the eukaryotic cytoskeleton perform essential and diverse functions and are composed of a heterodimer of alpha and beta tubulin. The genes encoding these microtubule constituents are part of the tubulin superfamily, which is composed of six distinct families. Genes from the alpha, beta and gamma tubulin families are found in all eukaryotes. The alpha and beta tubulins represent the major components of microtubules, while gamma tubulin plays a critical role in the nucleation of microtubule assembly. There are multiple alpha and beta tubulin genes and they are highly conserved among and between species. This gene is an alpha tubulin gene that encodes a protein 99% identical to the mouse testis-specific Tuba3 and Tuba7 gene products. This gene is located in the 13q11 region, which is associated with the genetic diseases Clouston hidrotic ectodermal dysplasia and Kabuki syndrome. [provided by RefSeq, Jul 2008] |
>TUBA3CP16 |
GTGCACAGGACTTCAGGGCTTCCTGGTGTTCCACAGCTTTGGTGGGGGCACTGGCTCTGGCTTCACCTCACTCCTGATGGAGCGGCTCTCTGTTGACTATGGCAAGAAATCCAAGCTGGAATTCTCCATCTACCCAGCCCCCCAGGTGTCTACAGCCGTGGTCGAGCCCTACAACTCTATCCTGACCACCCACACCACCCTGGAGCACTCAGACTGTGCCTTCATGGTGGACAACGAAGCAATCTATGACATCTGCCGCCGCAACCTAGACATCGAGCGCCCAACCTACACCAACCTCAATCGCCTCATTAGCCAAATTGTCTCCTCCATCACAGCTTCTCTGCGCTTTGACGGGGCCCTCAATGTGGACCTGACAGAGTTCCAGACCAACCTGGTGCCCTACCCTCGCATCCACTTCCCCCTGGCCACCTATGCACCAGTCATCTCTGCAGAAAAGGCATACCACGAGCAGCTGTCGGTGGCAGAGATCACCAATGCCTGCTTTGAGCCTGCCAACCAGATGGTAAAGTGTGATCCCCGGCACGGCAAGTACATGGCCTGCTGCCTGCTGTACCGTGGAGATGTGGTGCCCAAGGATGTCAACGCTGCCATTGCCGCCATCAAGACCAAGCGCAGCATTCAGTTTGTGGACTGGTGCCCCACAGGCTTCAAGGTTGGTATCAACTACCAGCCTCCCACTGTGGTGCCTGGGGGTGACCTGGCCAAGGTGCAGCGTGCCGTGTGCATGCTGAGCAACACGACCGCCATCGCCGAGGCCTGGGCCCGCCTGGACCACAAGTTCGACCTGATGTATGCCAAGAGGGCGTTTGTGCACTGGTATGTGGGTGAGGGCATGGAGGAGGGTGAGTTCTCCGAGGCCCGTGAGGATATGGCTGCCCTGGAGAAGGATTATGAGGAGGTGGGCA |
>NM_006001.3 |
GTCGTTGGGCGTGCGCAGCTGCAGCGGCGGTTGAGGTCAAGTAGTAGCGTTGGGCTGCGGCAGCGGAGGAGCTCAACATGCGTGAGTGTATCTCTATCCACGTGGGGCAGGCAGGAGTCCAGATCGGCAATGCCTGCTGGGAACTGTACTGCCTGGAACATGGAATTCAGCCCGATGGTCAGATGCCAAGTGATAAAACCATTGGTGGTGGGGACGACTCCTTCAACACGTTCTTCAGTGAGACTGGAGCTGGCAAGCACGTGCCCAGAGCAGTGTTTGTGGACCTGGAGCCCACTGTGGTCGATGAAGTGCGCACAGGAACCTATAGGCAGCTCTTCCACCCAGAGCAGCTGATCACCGGGAAGGAAGATGCGGCCAATAATTACGCCAGAGGCCATTACACCATCGGCAAGGAGATCGTCGACCTGGTCCTGGACCGGATCCGCAAACTGGCGGATCTGTGCACGGGACTGCAGGGCTTCCTCATCTTCCACAGTTTTGGGGGTGGCACTGGCTCTGGGTTCGCATCTCTGCTCATGGAGCGGCTCTCAGTGGATTACGGCAAGAAGTCCAAGCTAGAATTTGCCATTTACCCAGCCCCCCAGGTCTCCACGGCCGTGGTGGAGCCCTACAACTCCATCCTGACCACCCACACGACCCTGGAACATTCTGACTGTGCCTTCATGGTCGACAATGAAGCCATCTATGACATATGTCGGCGCAACCTGGACATCGAGCGTCCCACGTACACCAACCTCAATCGCCTGATTGGGCAGATCGTGTCCTCCATCACGGCCTCCCTGCGATTTGACGGGGCCCTGAATGTGGACTTGACGGAATTCCAGACCAACCTAGTGCCGTACCCCCGCATCCACTTCCCCCTGGCCACCTACGCCCCGGTCATCTCAGCCGAGAAGGCCTACCACGAGCAGCTGTCCGTGGCTGAGATCACCAATGCCTGCTTCGAGCCAGCCAATCAGATGGTCAAGTGTGACCCTCGCCACGGCAAGTACATGGCCTGCTGCATGTTGTACAGGGGGGATGTGGTCCCGAAAGATGTCAACGCGGCCATCGCCACCATCAAGACCAAGCGCACCATCCAGTTTGTAGATTGGTGCCCAACTGGATTTAAGGTGGGCATTAACTACCAGCCCCCCACGGTGGTCCCTGGGGGAGACCTGGCCAAGGTGCAGCGGGCTGTGTGCATGCTGAGCAACACCACGGCCATCGCGGAGGCCTGGGCTCGCCTGGACCATAAGTTCGATCTCATGTATGCCAAGCGGGCCTTTGTGCACTGGTACGTGGGAGAAGGCATGGAGGAGGGGGAGTTCTCTGAGGCCCGCGAGGACCTGGCAGCTCTGGAGAAGGATTATGAAGAGGTGGGCGTGGATTCCGTGGAAGCCGAGGCTGAAGAAGGTGAAGAATACTGAGGGGAGGGTGTGGTGGGTTCTCCACTCCACTGCCACCCCCAGCGTGGCTGCTTTCAAGTTCTTTGCAATTAAAGGTTCTGTATAAAACCAA |
PMID - Link | Title |
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