Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name CYCSP6
Plot displaying the genomic locations of a retrocopy (in chr2) and its respective parental gene (in chr7). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr2:78411902-78413110  UCSC
Coordinates (T2T) chr2:78416860-78418068  UCSC
Coordinates (hg19) chr2:78639028-78640236  UCSC
Strand -
Parental Sequence NM_018947.6
Parental seq. overlap 1110 bp
Parental seq. overlap (%) 20.4%
Genomic Region Intergenic
Retrocopy Summary CYCSP6, located on chr2:78411902-78413110, is a retrocopy of the parental gene CYCS. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name CYCS
Full Name cytochrome c, somatic
Also known as CYC|HCS|THC4
Coordinate chr7:25118656-25125260
Strand -
Gene summary This gene encodes a small heme protein that functions as a central component of the electron transport chain in mitochondria. The encoded protein associates with the inner membrane of the mitochondrion where it accepts electrons from cytochrome b and transfers them to the cytochrome oxidase complex. This protein is also involved in initiation of apoptosis. Mutations in this gene are associated with autosomal dominant nonsyndromic thrombocytopenia. Numerous processed pseudogenes of this gene are found throughout the human genome.[provided by RefSeq, Jul 2010]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes CYCSP6
Bonobo Pan paniscus LOC100986481P4
Gorilla Gorilla gorilla LOC101135431P5
Orangutan Pongo abelii CYCSP5
Gibbon Nomascus leucogenys LOC100580069P16
Crab-eating macaque Macaca fascicularis LOC102120205P8
Rhesus Macaca mulatta CYCSP22
Baboon Papio anubis LOC100997529P22
Golden snub-nosed monkey Rhinopithecus roxellana LOC104672188P23
Green monkey Chlorocebus sabaeus Without Homology
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>CYCSP6
AAAAAGAGAATGAAATGTGGGTGACGTTGAGAAAGGCAAGAAGATTTTTGTTCAGAAGTGTGCCCAGTGCCTAAAAGGGAGGCAAGCACAAGACTGGGCCTAACCTCCATGGTCTCTTTGGGCTGAAGACTGGTCAGGCCATTGGATTCTCTTACAAAGATGCCAGTAAGAACAAAGAGATCACCTGGGGAGAGGATACAGTGATGGAGCATTTGCAGAATCCCAAGAACTACATCCCTGGAACAAAAATGATCTTTGCTGGCATTCAGAAGAAGGCAGAAAGGGCAGACTTGATAGCTTATCTCAAAAAAAGCTACTCATGAGTAATAATTGGCCACTGCCTTATTTATTACAAAACAGAAATGTCTCATGACTTTTCTATGTGTACCATACTTTAATAGATCTCATACACCAGAATTCAGATCATGAATGACTGACAGAATATTTTACTGGGCAATCCTGATTTAAAACTAAGACTGGCTTGTGGTTAAATGAATGTGTTCAGTTTTTGAATTTTAATAGTAATTCCAATTCAGTAAATGCTATCACTGTTTACCCCTTCTAAAGATATGATTAGACTTCACTGGTAATGTTCAACTTTTCACAAAGATGGTGACTGCCATCTTAAAACTTACTGGATATTGGTTTATATTTAGATTTCTATAACTGGTTATGTGAATATATTTAAATACTCGGGAAATTCCTTCACTGTCTCAGAACCAAGCAAGATTCATCTGTGTTTTGTGTTCATTTGCCTCTTAAAGGCAAGGGTTGAAGATAAATAAGGTAGCAACGTCTACTTTATATTTTTGGCCTTAACTATGCCAATCTAATTAGAATTCTCTGCATTTAAACTGGTTCTTTTTACTTACTGAAGGGCATTTTAGTGTGGTTTATGTGTAATATCAAAGATTATTTAACATTTCTCACATTTTATAGATGATCTATAAGGTCACATGCTTTTAATATAGTAGCAAGTTAAACTTCACTCTTGAATTCTTTACAATCTAAGTCAAACTAAGTTATAATTTAAGATTGTCTTTAAACAGCCATTCAGATACATAAAACTGTGGAACTGCTCTGTATTTGTGATTGTGGATAGTGCTTTTGCCAACTTAAAAGAATTAAAGTAGAGGAGATATACATAAATTTTAAAATTATGTGTGATCATAAGACTTAAGATAATTAAAAAGAAATTCACAGATCATT
>NM_018947.6
AGAGAGTGGGGACGTCCGGCTTCGGAGCGGGAGTGTTCGTTGTGCCAGCGACTAAAAAGAGAATTAAATATGGGTGATGTTGAGAAAGGCAAGAAGATTTTTATTATGAAGTGTTCCCAGTGCCACACCGTTGAAAAGGGAGGCAAGCACAAGACTGGGCCAAATCTCCATGGTCTCTTTGGGCGGAAGACAGGTCAGGCCCCTGGATACTCTTACACAGCCGCCAATAAGAACAAAGGCATCATCTGGGGAGAGGATACACTGATGGAGTATTTGGAGAATCCCAAGAAGTACATCCCTGGAACAAAAATGATCTTTGTCGGCATTAAGAAGAAGGAAGAAAGGGCAGACTTAATAGCTTATCTCAAAAAAGCTACTAATGAGTAATAATTGGCCACTGCCTTATTTATTACAAAACAGAAATGTCTCATGACTTTTTTATGTGTACCATCCTTTAATAGATCTCATACACCAGAATTCAGATCATGAATGACTGACAGAATATTTTGTTGGGCAGTCCTGATTTAAAACTAAGACTGGCTTGTGGTTAAATGAATATGTTCAGTTTTTGAATTTTAATAGTAACTCCAATTCAGTAAATGGTATCACTGTTTACCCCTTTTAAAGATATGATTAGACTTCGTTAGTAATGTTCAACTTTTCACAAAGATGGTGAGTGCCATCTTAAAACTTACTGGAGATTGGTTTTATATTTAGATTTATATAACTGGTTATGTGAATATATTTAAATACTGGGGAAATTGCTTCACTGTCTTAGAACCAAGCAAGATTCACCTGTGTTTTGTGTTCATGTTCATTTGCCTCTTAAAGGCAAGGGTTGAAGATAAATAAGGTAGCAATGTCTATAGTTTTGGCCTTAACTATGCCAATCTAATTATAATTCCCTGTATTTAAAATGGTTTCTTTTACTTATTGAAAGGCATTTTAGTGTGGTTTATGTGTAATATTAAAGATTATTCAACACCTCTCACATCTTACAGATCTATAAGGTCACATGCTTTTAAAATAGTAGCAAGTTAAACTTCACTCTTGAATTCTTTACAATCTAAGTCAAACTAAGTTATAATTTAGGATTGTCTTTAAACAGCCATTCAGAAACAAAACTGTAGAACTGTGTATTTGATTGGGAATGGTGCTTTTGCCAACTTAAAAGGATTAAAGTAACGGAGATATACACAAATTTTAAAATTATGTGTGATCACAAGACTAAAGATAATTAAAAAGAAAACCACAGATCATGACTTTTTGACTGTGCTTGATTTCATGACTGATGCACAAATTTTAATGATTAAAAAGTGCAGGAGCCCTAAATGTCAGTGCAGCAGCCCTAAATGTCAGTGCAGCAGTGTTAACCAGTCATGGTGCTAGATTGTTTACTTGGTTTTCTAGGACTGCCTCAACTAGAATAACACTTCACTAATTGACTCTTAGTTTCTTTGCTCAGATTGAGAACTGCAGCATTTATGCCAGACATGGACAGAGGAATGCCTGTGGTCATAGTTTTGTGATGTGTAACAGTGTATAATTACATACTGAATTATTTCATGCATAGTCTGTGCCATACACATTTAGAGTAGTCCTTGGAGATTTTATGGAGATGGTGAGCACAAGGTAAGTCATAAAGAATAATGAGAAAATAAATCTATGCTGGTGCAGCTGAGAACTGTATCTTTGTGGGACAGTGAGAAGACTGAGAAGATGTGAATCCATGGTCTCAAAGGTGATAGGGACGATTAGATAGGTGTTTTAAGGCCTGAAAGCAATTTATAACATATGAGTCTTATTTTTATTTATAGAAATGTGGAAAGCTTGCTGTAATTCATATTTGAAGTCCTAGTCTGAGTTCTGGTGGGGAATTTAAAAATGCATCCTGGAAATCCTTTAAAGATTTCAGACTTTGAAAGGCCTTGTAGCAGAGGACTTGGTGACTGTATAAAGTTAGTGGTATTCAGGGACAGTGTAGCAAGTAGCTTACAAGGGGACAATTCTGGACTAATGAGAAAGACCTGAAGTGAAGGCTAGAGAGTTGATTTTTTTTTTTTTTGGCATCCTGGAAATGATACAGGAAACATATTAAGATAGATACAGAAATGTGTTCAACCTTCCATCTTGGCTAGTTGTGGCGTTTAGtttgttttttgagacatggtcacgctgtgtcgccaaggctggagtgcagtggtgcgatctcggctggctgcaacctctatttcccaggctcaagcgattctctcacttcagcttcccaagtagctgggactacaggtgttcgccaccatgcccagctaatttttttgtagagatggagttttgccatgtggtcccaggctggtctcaaactcctgagctcaagcaatccgtccacttgccttggctccccaaagtgctgggattacaggcgtgagccaccaggccctgccTGGTTTTCAAATTCAGAAATCTTATTATTTAACCCAGAAGTAATCAGCCCAGTAGTAACTTAGGTTTAATTTTTTTTCAGGTTTAAAAtttttctcatttattttttctgagacggagtttcgcccttttcgcccaggctgagtacagtggtgcaatctcactgcaacctccgccttccagttgcaagtgattctcctgcctcagcctcctgagtagctgggattacaggcacccgccaccacgcctggctaatttttgtatttttagtggagatggtgtttcaccatgttggccagactggtcttggactcctgacctcgtgatccacccaccttggcctcccaaagttctaggattacaggtgtgagccaccacgtccggccAATTTTTCTCATTTCTATGCCTCCTATATTAAGGTCTGTGTTGGCACAGATGAGTAACTGCCATGTTCTAGGTCAGTTATACCCAAGCACTTCTGGTGGTTTAAAATGTGATTCTGTAACttttttatttttatttttttgagataatttcactcttgttgcccaggctggagtgcaatggcgtgatcgctgctcaccgcaacctccgccttccaggttcaagcgattctcctgactcagcctctcaagtagctgggattacaagcatgcgccaccatgcccagcttattttgtgtttttagtagagacagggtttctccatgctggacaggctggtcttgaactcccgacgtcaggtgatctacctgcctcggcctcccaaagtgctgggattacaggcgtgagccaccacgcctggccAATTATGTAATTTTTTAAAAAGGACATTTCTATCAGGGATATATACCTTCAGAAATAAGGAAATAGGGGAAAAAAAGAGCACTATAAACCACATGTTTTCATTTCTAGTGCTTCGCTGTAAGTGGCTAGGTTGGTAGAATCAAAAACAAGGGCCAGATGTATTTAAGGGGTATTCAGATGCCACCTACATGCTTATTTTGTCTAGAAcagtgctgtctaatagaactttctgtgacgatggatattttgtagacttttgctgtccagtgtggtagccactaaccacatgtggctgttaagcccttgaaatatagctagtgtgactagaaagtattttattttaaatttacataggcacaagtggctagtggctactgtattgACATTCTGGGTCTAGGACTAGAACCAGTGGTCTGTAACAAAAGTACTTTCTCTTTACTCTATTAAATCTAGAATTAgccgggcatggtcgctcatgcctgtaatcccagcactttgggaggccaaggcaggcagatcacttgaggtcaggcgtttgagaccagcctggtcaacatggcgaaaccctgtctctacaaaaaacataaaaattagccaggtgtggtggtgggcacctgtaatctcagctacttgggaggctgaggcacaagaatcacttgaacttgggaggtggaggttgcagtgagccaagattgtgccactgcactcaagcctgggtgacgagtgaaactgtctccaaaaaaaaaaaaaaaTCTAGAATTCTTGGAAGTACATTATATTGCCCTTCAGAATAGATTCCAGTTCCTGTTGTGCTCACCTTTATAATTTTACCATAAGTTTTACCTATTCGTAAGTTGGCAGTTTTAGATAGATAACATTCTGGTGGTAGCTAGGGATTTACCTTTTGTCATCCTTTTCCTGCACTTCTCTTGAATTCCTTTATAGATGTACAGTTTTGCTTTAACCACTGAAGATTGCTGTAAATTATAAAGGGTGTGATAGAATCCACATGGCTGTCAAGAAGGAGATCTTACCAAGGACAGTTGACTGACTAGTCTCAGATTGTTTCATATCATTTATACTTGGGTAAGAGTAAACTAGATAActgggcgtcgtggtgcacacctgtagtcccagccactctgaggcaggaggactgcttgtgcccagaagttcgaggctgcagtgtagctgtgattgtgctactgcactccagcctgggcaacagataaaggaaactccatctcttttaaaaaaaaaaaaaGTGGTctgggtgcagtaggtcatgcctgcaatcccagcactttgggaggccaaggcaggcagatcacctgaggtcaggagcttgagaccagcctggccaacatggtgaaaccccatctctaccaaaaatataaaaactagctgggcgtggtggcggcacctgtaattgcagctatttgagaggctgaggcaggagaatcgcttgaacctgggagatgggggttgcagtgagccaagaccgccccatcgcactccagcctgggcaacaatagtgaaactccgtctcaaaaagaaaaaaaGTTTCCTTAGAATGGAAAATATTCATTCATGAGCTCTTTTGGCAATCCGTCATCAGTATATTCTGAAAACCAATAAGATGTTGCCAAGTTGGGGGCGAGAGCTATGTAATGCAAGGCATATGCCTGATGAAGTATACAAATACACCTGACCAGAAACTTTGTCTCCCACATAAGTCTCTTCTAGGCACTGTCGGGGTACATACTGAGCTGCTGCTTTGGCTGTATTTTCTGTGCCTCAGAATAACCATTGTCCTGGTGTTCATATCCTTAGAGTTCAGTACAAAATGTTGGATATCCATTTAATAGGTTCCAGGTTATCTTAGTTGGAGTTTGGGGTATTTGAAAACGTCATGCCTTCAGGCTATCATTTCCCTCAGAAAGCTAAGTAAATTTACTGCATTCATTTCTCAAAGAGTAAAAGTGCAGGTTGTATGTGTCTATGAACATTTAAACATGTTAAAATGTTAAATTTAACATTTTAAATTTAAACATTTAAATATGTCTGTAACTTGAACAGTGTAGTTTCAGAAAGGACCACTGGGCTAGTGTAATGCAGAAAATGCTGGGTCTAGGATTAGGAGAAAATTGTGTTTAGTGTGTATCAATAAacagcccgtggacccaa

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