Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name FXNP3
Plot displaying the genomic locations of a retrocopy (in chr3) and its respective parental gene (in chr9). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr3:27525093-27525389  UCSC
Coordinates (T2T) chr3:27527192-27527488  UCSC
Coordinates (hg19) chr3:27566584-27566880  UCSC
Strand +
Parental Sequence NM_000144.5
Parental seq. overlap 251 bp
Parental seq. overlap (%) 3.6%
Genomic Region Intergenic
Retrocopy Summary FXNP3, located on chr3:27525093-27525389, is a retrocopy of the parental gene FXN. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name FXN
Full Name frataxin
Also known as CyaY|FA|FARR|FRDA|X25
Coordinate chr9:69035752-69079076
Strand +
Gene summary This nuclear gene encodes a mitochondrial protein which belongs to the FRATAXIN family. The protein functions in regulating mitochondrial iron transport and respiration. The expansion of intronic trinucleotide repeat GAA from 8-33 repeats to >90 repeats results in Friedreich ataxia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2016]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes FXNP1
Bonobo Pan paniscus FXNP1
Gorilla Gorilla gorilla FXNP1
Orangutan Pongo abelii FXNP1
Gibbon Nomascus leucogenys FXNP1
Marmoset Callithrix jacchus FXNP4
Green monkey Chlorocebus sabaeus Without Homology
Crab-eating macaque Macaca fascicularis Without Homology
Rhesus Macaca mulatta Without Homology
Baboon Papio anubis Without Homology
Golden snub-nosed monkey Rhinopithecus roxellana Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>FXNP3
TCTCAATCAGATTCTGAAAGTTAAAAAGCACAGTGTCTATTTGACAAATTTGAGGAAATCGGGAACTTTGGGTGACCTAGGCTCTCTAAATGAGATGACCTATCAAATACCAGCAGAGGAAATGCTGGACTCCTAAGCAGAATTTTTTTGGAAGACCTTGCAGATGAGGCTTACCAATTTGAGCACTATGATGTCTCCTTTGGGAATGGTGTCTTAACAATTAAACTGAGTGAAGATCTAGGAACCTATATGACAAACAGCAGACCCCAAATAAGCAAATCTGGTTATCTTCCCCAT
>NM_000144.5
AGGGCGGAGCGGGCGGCAGACCCGGAGCAGCATGTGGACTCTCGGGCGCCGCGCAGTAGCCGGCCTCCTGGCGTCacccagcccagcccaggcccagaccctcacccGGGTCCCGCGGCCGGCAGAGTTGGCCCCACTCTGCGGCCGCCGTGGCCTGCGCACCGACATCGATGCGACCTGCACGCCCCGCCGCGCAAGTTCGAACCAACGTGGCCTCAACCAGATTTGGAATGTCAAAAAGCAGAGTGTCTATTTGATGAATTTGAGGAAATCTGGAACTTTGGGCCACCCAGGCTCTCTAGATGAGACCACCTATGAAAGACTAGCAGAGGAAACGCTGGACTCTTTAGCAGAGTTTTTTGAAGACCTTGCAGACAAGCCATACACGTTTGAGGACTATGATGTCTCCTTTGGGAGTGGTGTCTTAACTGTCAAACTGGGTGGAGATCTAGGAACCTATGTGATCAACAAGCAGACGCCAAACAAGCAAATCTGGCTATCTTCTCCATCCAGTGGACCTAAGCGTTATGACTGGACTGGGAAAAACTGGGTGTACTCCCACGACGGCGTGTCCCTCCATGAGCTGCTGGCCGCAGAGCTCACTAAAGCCTTAAAAACCAAACTGGACTTGTCTTCCTTGGCCTATTCCGGAAAAGATGCTTGATGCCCAGCCCCGTTTTAAGGACATTAAAAGCTATCAGGCCAAGACCCCAGCTTCATTATGCAGCTGAGGTCtgttttttgttgttgttgttgtttattttttttattcctgcttttgAGGACAGTTGGGCTATGTGTCACAGCTCTGTAGAAAGAATGTGTTGCCTCCTACCTTGCCCCCAAGTTCTGATTTTTAATTTCTATGGAAGATTTTTTGGATTGTCGGATTTCCTCCCTCACATGATACCCCTTATCTTTTATAATGTCTTATGCCTATACCTGAATATAACAACCTTTAAAAAAGCAAAATAATAAGAAGGAAAAATTCCAGGAGGGAAAATGAATTGTCTTCACTCTTCATTCTTTGAAGGATTTACTGCAAGAAGTACATGAAGAGCAGCTGGTCAACCTGCTCACTGTTCTATCTCCAAATGAGACACATTAAAGGGTAGCCTACAAATGTTTTCAGGCTTCTTTCAAAGTGTAAGCACTTCTGAGCTCTTTAGCATTGAAGTGTCGAAAGCAACTCACACGGGAAGATCATTTCTTATTTGTGCTCTGTGACTGCCAAGGTGTGGCCTGCACTGGGTTGTCCAGGGAGACCTAGTGCTGTTTCTCCCACATATTCACATACGTGTCTGTGTGTATATATATTTTTTCAATTTAAAGGTTAGTATGGAATCAGCTGCTACAAGAATGCAAAAAATCTTCCAAAGACAAGAAAAGAGGAAAAAAAGCCGTTTTCATGAGCTGAGTGATGTAGCGTAACAAACAAAATCATGGAGCTGAGGAGGTGCCTTGTAAACATGAAGGGGCAGATAAAGGAAGGAGATACTCATGTTGATAAAGAgagccctggtcctagacatagttcagccacaaagtagttgtccctttgtggacaagtttcccaaattccctggacctctgcttccccatctgttaaatgagagaatAGAGTATGGTTGATTCCCAGCATTCAGTGGTCCTGTCAAGCAACCTAACAGGCTAGTTCTAATTCCCTATTGGGTAGATGAGGGGATGACAAAGAACAGTTTTTAAGCTATATAGGAAACATTGTTATTGGTGTTGCCCTATCGTGATTTCAGTTGAATTCATGTGAAAATAATAGCCATCCTTggcctggcgcggtggctcacacctgtaatcccagcacttttggaggccaaggtgggtggatcacctgaggtcaggagttcaagaccagcctggccaacatgatgaaaccccgtctctactaaaaatacaaaaaattagccgggcatgatggcaggtgcctgtaatcccagctacttgggaggctgaagcggaagaatcgcttgaacccagaggtggaggttgcagtgagccgagatcgtgccattgcactgtaacctgggtgactgagcaaaactctgtctcaaaataataataacaatataataataataataGCCATCCTTTATTGTACCCTTACTGGGTTAATCGTATTATACCACATTACCTCATTTTAATTTTTACTGACCTGCACTTTATACAAAGCAACAAGCCTCCAGGACATTAAAATTCATGCAAAGTTATGCTCATGTTATATTATTTTCTTACTTAAAGAAGGATTTATTAGTGgctgggcatggtggcgtgcacctgtaatcccaggtactcaggaggctgagacgggagaattgcttgaccccaggcggaggaggttacagtgagtcgagatcgtacctgagcgacagagcgagactccgtctcaaaaaaaaaaaaaaGGAGGGTTTATTAATGAGAAGTTTGTATTAATATGTAGCAAAGGCTTTTCCAATGGGTGAATAAAAACACATTCCATTAAGTCAAgctgggagcagtggcatatacctatagtcccagctgcacaggaggctgagacaggaggattgcttgaagccaggaattggagatcagcctgggcaacacagcaagatcctatctcttaaaaaaagaaaaaaaAACCTATTAATAATAAAACAGTATAAACAAAAGCTAAATAGGTAAAATATTTTTTCTGAAATAAAATTATTTTTTGAGTCTGATGGAAATGTTTAAGTGCAGTAGGCCAGTGCCAGTGAGAAAATAAATAACATCATACATGTTTGTATGTGTTTGCATCTTGCTTCTACTGAAAGTTTCAGTGcaccccacttacttagaactcggtgacatgatgtactcctttatctgggacacagcacaaaagaggtatgcagtggggctgctctgacatgaaagtggaagttaaggaatctgggctcttatggggtccttgtgggccagcccttcaggcctattttactttcattttacatatagctctaattggtttgattatctcgttcccaagGCAGTGGGAGATCCCCATTTAAGGAAAGAAAAGGggcctggcacagtggctcatgcctgtaatcccagcactttgggaggctgaggcaagtgtatcacctgaggtcaggagttcaagaccagcctggccaacatggcaaaatcccgtctctactaaaaatattaaaaaattggctgggcgtggtggttcgtgcctataatttcagctactcaggaggctgaggcaggagaatcgctgtaacctggggggtggaggttgcagtgagacgagatcatgccacttcactccagcctggccaacagagccatactccgtctcaaataaataaataaataaataaaGGGACTTCAAACACATGAACAGCAGCCAGGGGAAGAATCAAAATCATATTCTGTCAAGCAAACTGGAAAAGTACCACTGTGTGTACCAATAGCCTCCCCACCACAGACCCTGGGAGCATCGCCTCATTTATGGTGTGGTCCAGTCATCCATGTGAAGGATGAGTTTCCAGGAAAAGGTTATTAAATATTCACTGTAACATACTGGAGGAGGTGAGGAATTGCATAATACAATCTTAGAAAACttttttttcccctttctattttttgagacaggatctcactttggcactcaggctggaggacagtggtacaatcaaagctcatggcagcctcgacctccctgggcttgggcaatcctcccacaggtgtgcacctccatagctggctaatttgtgtattttttgtagagatggggtttcaccatgttgcccaggctggtctctaacacttaggctcaagtgatccacctgcctcgtcctcccaagatgctgggattacaggtgtgtgccacAGGTGTTCATCAGAAAGCTTTTTCTATTATTTTTACCTTCTTGAGTGGGTAGAACCTCAGCCACATAGAAAATAAAATGTTCTGGCATGACTTATTTAGCTCTCTGGAATTAcaaagaaggaatgaggtgtgtaaaagagaacctgggtttttgaatcacaaatttagaatttaatcgaaactctgcctcttacttgtttgtagacactgacagtggcctcatgttttttttttttttaatctataaaatggagataTCTAACATGTTGAGCCTGGGCCCACAGGCAAAGCACAATCCTGATGTGAGAAGTACTCAGTTCATGACAACTGTTGTTCTCACATGCATAGCATAATTTCATATTCACATTGGAGGACTTCTCCCAAAATATGGATGACGTTCCCTACTCAACCTTGAACTTAATCAAAATACTCAGTTTACTTAACTTCGTATTAGATTCTGATTCCCTGGAACCATTTATCGTGTGCCTTACCATGCTTATATTTTACTTGATCTTTTGCATACCTTCTAAAACTATTTTAGCCAATTTAAAATTTGACAGTTTGCATTAAATTATAGGTTTACAATATGCTTTATCCAGCTATACCTGCCCCAAATTCTGACAGATGCTTTTGCCACCTCTAAAGGAAGACCCATGTTCATAGTGATGGAGTTTGTGTGGACTAACCATGCAAGGTTGCCAAGGAAAAATCGCTTTACGCTTCCAAGGTACACACTAAGATGAAAGTAATTTTAGTCCGTGTCCAGTTGGATTCTTGGCACATAGTTATCTTCTGCTAGAACAAACTAAAACAGCTACATGCCAGCAAGGGAGAAAGGGGAAGGAGGGGCAAAGTTTTGAAATTTCATGTAAATTTATGCTGTTCAAAACGACGAGTTCATGACTTTGTGTATAGAGTAAGAAATGCCttttcttttttgagacagagtcttgctctgtcacccaggctggagtgcagtggcacgatctgggctcactacaacctccgcctcctgggttcaagcaattctctgcctcagcctcccgagtagctgggattacaggtgcctgccaccacacccggctaatttttgtatttttagtagagacggggtttcaccatcatggccaggctggtcttgaactcctgacctagtaatccacctgcctccgcctcccaaagtgctgggattacaggcgtgagccactgcacccagccAGAAATGCCTTCTAATCTTTGGTTTATCTTAATTAGCCAGGACACTTGGAGTGCATCCCGAAGTACCTGATCAGTGGCCCCTTTGGAATGTGTAAAACTCAGCTCACTTATATCCCTGCATCCGCTACAGAGACAGAATCCAAGCTCATATGTTCCATCTTCTCTGGCTGTATAGTTTAAGGAATGGAAGGCACCAGAACAGATTTATTGAAATGTTTATTAGCTGAAGATTTATTTAGACAGTTGAGGAAAACATCAGCACCCAGCAGTAAAATTGGCTCTCAAAGATTTTCTTCTCCTGTGGAAAGTCAGACCTCTGAGGCCCCATCCAGGTAGAAGTACTAGTGCAAGAAGGGCCTCTGCTGTCCACTTGTGTTTCTGTGATCTGTGGGAACATTGTTAACGCCACATCTTGACCTCAAATTGTTTAGCTCCTggccagacacggtggctcacacctgtaatcccagcactttgagaggctgaggcaggtggatcacctgaggttaggagttcgaggccagcctggtcaacatggtaaaaccccgcctctactaaaaatacaaaaattagctggccgtagtggcgcacgcctgttatcccagctactcgggaggctgaggcaggagaattgcttgaacctgggtggtggaggttgcagtgagccgagattacaccactgcactccagcctgggtgacaagagggaaactccattaaaaaaaTGTAATTCCCGTGTCTGCCATCTTAAGTGTAAAGGTGGCTAAATTATATAGAAAAATAAGACAATATCATTTCCCAATTACATTCCTTTCCTACCGCACTCTATGATGCTAGCTGAGATTTTTCCAAAAGAAAATGGCTTAAATAAAACCCTAAGAGAAAGAAAAACTTTAAATCCCTCCAAAGCTCAAAAGTAATAGAAACAGATGAGTTTGGAGTcaggatttctctgtaagattgcctaggctgtgtactgcacatctccaggtgccactgttgacagagattataactacaatgtgaagtgaatggtgccactgacagttatgcaAACCGTCCAGAGCATAGCCACCTGATCCTGCTGGGATTCCTCTTGCCAGTCCATCAGCAGTTCCCCTTGAAAGTTTCACCAAACATCCCTTAAATCTGCCCTCTCCTGCCCGTCCCCAGTGGAGGTCCTCATCATTTTTCACCTGCATTTTTGCAGGAGCTTTCTTATATCCACCTTCCTCCTTTTCTCTCAGCCCATCATCTAGCTACACAGTCTCCAGGGTAAGCTTTCAGAAAGGCAATCTCTTGTCTGTAAAACCTAAGCAGGACCAAGGCCAAGTTTCTTAGCCTGAAAAATGTGCTTTTCTGACTGAACTGTTCAGGCACTGACTCTACATATAATTATGCTTTTCTACCCCCTCACACTCAACACTTTGACTCCAGCAATCCCAAATCCCCAGATCCCTAAGTGTGCTGTGCTATTTTCACGTGGCTCTCAGACTTGGCCAGTGCTGTTTCCATTTTGGTCTTTATTCCCCACATCTCTGCCTGGGGGGTAGATTCTACCCTGAAAAATGTTCTTGGCACAGCCTTGCAAACTCCTCCTCCACTCAGCCTCTGCCTGGATGCCCTTGATTGTTCCATGTCCTCAGCATACCATGTTTGTCTTTCCCAGCACTGACCTACCAtgtgtcacccctgcttggctgtaccttccatgaggctaggactatgtgtctcctttgttgactgctgttgccctagcatcttgcacagttccttgcacacaattagagctctataaatgtcaaataaatgTGTTATAATTATATGTTTAAGATAGTTGTTCAAATAAACTCTAAATAACCCCAA

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