Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name SOCS5P3
Plot displaying the genomic locations of a retrocopy (in chr3) and its respective parental gene (in chr2). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr3:44707168-44711053  UCSC
Coordinates (T2T) chr3:44722859-44726735  UCSC
Coordinates (hg19) chr3:44748660-44752545  UCSC
Strand -
Parental Sequence NM_144949.3
Parental seq. overlap 1631 bp
Parental seq. overlap (%) 25.8%
Genomic Region Intergenic
Retrocopy Summary SOCS5P3, located on chr3:44707168-44711053, is a retrocopy of the parental gene SOCS5. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name SOCS5
Full Name suppressor of cytokine signaling 5
Also known as CIS6|CISH6|Cish5|SOCS-5
Coordinate chr2:46698937-46763129
Strand +
Gene summary The protein encoded by this gene contains a SH2 domain and a SOCS BOX domain. The protein thus belongs to the suppressor of cytokine signaling (SOCS) family, also known as STAT-induced STAT inhibitor (SSI) protein family. SOCS family members are known to be cytokine-inducible negative regulators of cytokine signaling. The specific function of this protein has not yet been determined. Two alternatively spliced transcript variants encoding an identical protein have been reported. [provided by RefSeq, Jul 2008]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes SOCS5P1
Bonobo Pan paniscus SOCS5P1
Gorilla Gorilla gorilla SOCS5P1
Orangutan Pongo abelii SOCS5P1
Green monkey Chlorocebus sabaeus SOCS5P2
Rhesus Macaca mulatta SOCS5P1
Baboon Papio anubis SOCS5P2
Golden snub-nosed monkey Rhinopithecus roxellana SOCS5P1
Gibbon Nomascus leucogenys Without Homology
Crab-eating macaque Macaca fascicularis Without Homology
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>SOCS5P3
CAGTGCAGTTAATTCTTAATGGAAAATCAGAAACCTAAATTGCAGATTTAAAAGGTACTGTACAGCCATTATATCTGTAAATAACTTAGCACGTTTTTGTCACTTAGAATAATATGTGCTACTACGTGAGTGAGCTCTTTTGGAAGTTATATCAAGTTCTAGTGTTTGTTTCTTAATAACTGAACTGAATTTGCAGTCCTAGACATTTTGCACTAAAGTAGCCGAATCCATTCTTGTGCCTTTTTGTTAATGTGCTCTGTATCACTGGTGAGTGCTTCATAGTTTCCTTACCTGCTGCTACAGAATGTTATTTTACATCTTTATGGCTATCGCCAAGGCTGCAAAAAAGAAAAGCTATATTTGTATACAACACTAACCCTTTGACTGCTAATGTATGTTTTTGCTTGCTGTGCCTTGTTATGACTGCTTTTTTGTGCTAATAAAGTATGTTTGGTGTAGTATCATTATAAACACAAAGTTAGAGTTTGCTGGTTAGAACGAGAACCAGTCAAGGCAGAGTAAACTCTCCTGTCCCCAAAGGGTGTTAACTAGGTCCGCTTTCATGTGCATCAGGCAGTACACCTACAGCAAACACACGTAGCAGTGTTAGGCTTTTTCATACAGTATGTAAGCTTAGTGTTAGTGTCTGTCAGATGCGACCTACTGTTATTTGTTCAGATAAACATGGTGCCTATTGGAACAACAGAGGATAGAGCTACAGGTGTTCAGTAAGACTACAAACACATTTTGCCGATTTCACTAACAATTTGGTTTTTAATGGCTGTAGTATTTGAGTGAGGCAACACTGGGGCATTTGTTATGAAGAATTCTATTTCTTACTGAGGAACAAATTATTAATACTGAATGAGTATTTCAACAGTGTGACTAATGTTTGAAATTATTTTTTCTAAGAGTTTTTCTACAATCTTCCAAACGTAATGATGTTTGTATTTACTATAAATCAAGCTTTGGAAGTCGAAAAAATAAATAAATAAAAGACTGCCTTCATTTTAGAAAAAAATGCAATTTTCTGGCCACAAGGGCATAGTGCAGTTCACTTAACTGTTGATGTAGTTTATAATCAGACGCCTTTTCTCTTCTGCAAAAGGTACTGTTAAGAAAACCAGATTTTCTAAATAGCCATTCTTAAAATTTCAGACTTACAAAGCTAGTAGTAGAATTTTATTGAAAGGCCCTAGGTTTTTTTTTTTTAATGAGTGCTTTAACTTAAAACAGGCATTTGAAATACCTGTTGCAATGCAGTCTTGCGTGTGATTTTTTTTCAGTTGATGTACAGTCTAATTGTTTCATAAAAGTTGGATCTTTTCCTATGTCCAGGATGATTTTGTGAACTATGAAGTACATGAGACTAGAAGATGCCCAAGCAAGTCAGATAATAGTAACTACAATGGTTGCTGGTTGCTGATATTGAGGTTATTGTTGAACTGTAATTAATAATTTGGATGGCAGTATTTATCTCTTTTTTGTAAACTCTCATACCTGAATTGCTTAAGTATAATTTATAGAATTTCAGTGCAGTTAAGTCCGGAGGAAGCGAGGCTGCGCTCGCTGGGCAGTCGGAGGGGACGGGACGCACCAGAGGGTGGGTGGACTCGCCCTGTAGGTGACTGCGCCGTCCAGGCCCGTCCTGCCTGGCCTTAGGTGTCCTGGATGAGGCTGCCCCGTGCGCCCCCGATGATTTTATAATCAATGGATAAAGTGGGGAAAATGTGGAATAACTTCAAGTACAGGTGTCAGAATCTCTTCGGTCATGAAGGAGGAAGCTGTAGTGAAAATGTTAACATGAACTCCGACAAATGTCTGTCTGTCAAAGAGAAAAACATCAGCATAGGAGACTCAACTCCTCAGCACCAAAACCGTCCCTTAAGAGAAGATGTTGCCTTACAACTGGGATTAAGCCCTTCAAATAATTCTTCAAAGAGAAATCAAAATTGTGCCACCGAAATTCCTCAAATTGTTGAAATAAGCATCGAAAAGGATAATGATTCTTGTGTTACCCCAGGAACAAGAGTTGCACGAAGAGATTCCTACTCTCGACATGCTCCATGGGGTGCGAGGAAAAAACATTCCTGTTCTACTAAGACCTAGAGTTCATTGGATACTGATCAAATGTTTGTTAGAACTCGAAGTGGACTTCAAAGGAGAGAGAGGCGCTATGGTGTAAGTTCTGTACACGACATGGACAGTGTGTCCAGCAGAACTGTAGGAAGTCGCTCTCTGAGAAAGACGTTGCAGGATACTGTGGGCTTGTGTTTTCCCATGAGAACTTACAGCAAGCAGTCAAAGCCTCTCTCTTCCAATAAAAGAAAAATCCATCTTTCTGAATTAATGCTTGAGAAATGCCCTTTTCCTGCTGGCTCAGATTTAGCCCAAAAATGGCATTTGATTAAACAGCATACAGCTCCTGTGAGCCCACATTCAACATTTTTTGATACACTTGATCCATCTTTGGTTTCTACAGAAGACGAAGAAGTTAGGCTTAGAAAGACAAGACGGCTTAGTATTGAAGAAGGGGTTGATCCCCCGCCCAGTGCACAAGTACATACATTTGAAGCTACTGCACAGGTTAATCCATTATATAAACTGGGACCAAAGTTAGCTCCCGGAATGACTGAAATAAGTGGGGACAGTTCTGCAATTCCACAAGTTAATTGTGACTCGGAAGAGGATACAACCACCCTGTGTTTGCAATCACGGAGGTAGAAGCAGCGTCAGATATCTGGAGACAGCCATACCCATGTTAGCAGACAAGGAGCTTGGAAAGTCCACACACAGATTGATTACATATAGGTCTCGTGCCTGATTTGCTTCAAATTACAGGGAATCCCTGTTACTGGGGAGTGGTGGACCGTTATGAAGCAGAAGCCCTTCTTGAAGGGAAACCTGAAGGCACGTTTTTGCTCAGGGACTCTGCACAAGAGGACTACCGGAAACTCTGTGAGTTTCCGCCTCTACAATAGATCCCTGCATGCCCGAGTTGAGCAGTGGAATCACAACTTTAGTTTCGATGCCATGACCCGTGTATATTTCATTCCTCCACGGTAACTGGACTTTTAGAACATTATAAAGATCTCAGTTAGTGCATGTTTTTTTGAACCATTGCTTGCTATATCACTAAATAGGACTTTTCCTTTTAGCCTGCGGTATATCTGTCGCACAGTAATCTGCAGATGCACTACGTATGATGGAATTGATGGGCTCCCTCTACCCTCAATGTTACAGGACTTTTTAAAAAAGTATCATTATAGAAc
>NM_144949.3
GTCCGGAGGAAGCGACGCTGCGCTCGCTGGGCAGTCGGAGGGGACGGGACGCACCGGAGGGCAGGCGGACTCGCCCTGTCGGTGACTGCGCCGTCCGGGCCCGTCCTGCCTGGCCGCAGGTGCCCTGGATGAGGCCGCCCCGCGCGCCCCAAACGATTTTATAATCAATGGATAAAGTGGGAAAAATGTGGAATAACTTCAAATACAGGTGTCAGAATCTCTTCGGTCATGAGGGAGGAAGCCGTAGTGAAAATGTGGACATGAACTCCAACAGATGTTTGTCTGTCAAAGAGAAAAACATCAGCATAGGAGACTCAACTCCTCAGCAACAAAGCAGTCCCTTAAGAGAAAATATTGCCTTACAACTGGGATTAAGCCCTTCGAAGAATTCTTCAAGGAGAAATCAAAATTGTGCCACAGAAATCCCTCAAATTGTTGAAATAAGCATCGAAAAGGATAATGATTCTTGTGTTACCCCAGGAACAAGACTTGCACGAAGAGATTCCTACTCTCGACATGCTCCATGGGGTGGGAAGAAAAAACATTCCTGTTCTACAAAGACCCAGAGTTCATTGGATGCTGATAAAAAGTTTGGTAGAACTCGAAGTGGACTTCAAAGGAGAGAGAGGCGCTACGGCGTAAGTTCTGTACACGACATGGACAGTGTTTCCAGCAGAACTGTAGGAAGTCGCTCTCTAAGACAGAGGTTGCAGGATACTGTGGGCTTGTGTTTTCCCATGAGAACTTACAGCAAGCAGTCAAAGCCTCTCTTTTCCAATAAAAGAAAAATCCATCTCTCTGAATTAATGCTTGAGAAATGCCCTTTTCCTGCTGGCTCAGATTTAGCCCAAAAATGGCATTTGATTAAACAGCATACAGCTCCTGTGAGCCCACATTCAACATTTTTTGATACATTTGATCCATCTTTGGTTTCTACAGAAGATGAAGAAGATAGGCTTAGAGAGAGAAGGCGGCTTAGTATTGAAGAAGGGGTTGATCCCCCTCCCAATGCACAAATACATACATTTGAAGCTACTGCACAGGTTAATCCATTATATAAACTGGGACCAAAATTAGCTCCTGGAATGACTGAAATAAGTGGGGACAGTTCTGCAATTCCACAAGCTAATTGTGACTCGGAAGAGGATACAACCACCCTGTGTTTGCAGTCACGGAGGCAGAAGCAGCGTCAGATATCTGGAGACAGCCATACCCATGTTAGCAGACAGGGAGCTTGGAAAGTCCACACACAGATTGATTACATACACTGCCTCGTGCCTGATTTGCTTCAAATTACAGGGAATCCCTGTTACTGGGGAGTGATGGACCGTTATGAAGCAGAAGCCCTTCTCGAAGGGAAACCTGAAGGCACGTTTTTGCTCAGGGACTCTGCGCAAGAGGACTACCTCTTCTCTGTGAGCTTCCGCCGCTACAACAGATCCCTGCATGCCCGAATTGAGCAGTGGAATCACAACTTTAGTTTCGACGCCCATGACCCGTGTGTATTTCACTCCTCCACTGTAACGGGACTTTTAGAACATTATAAAGATCCCAGTTCGTGCATGTTTTTTGAACCATTGCTTACTATATCACTAAATAGGACTTTCCCTTTTAGCCTGCAGTATATCTGTCGCGCGGTAATCTGCAGGTGCACTACGTATGATGGAATTGATGGGCTCCCTCTACCCTCAATGTTACAGGATTTTTTAAAAGAGTATCATTATAAACAAAAAGTTAGAGTTCGCTGGTTGGAACGAGAACCAGTCAAGGCAAAGTAAACTCTCCGGTCCCCAAAGGTTGTTAACTAGGTCCGCTTTCATGTGCATCAGACAGTACACCTATAGCAAGCACACGTAGCAGTGTTAGGCTTTTTCATACAGTATGTAAGCTTAGTGTTAGTATCTGTCAGATGCTACCTGCTGTTACTTATTCAGATAAACATGGTGCCTATTGGAACAATAGCGGATAGAGCTACAGGTGTTCAGTAAGACTACAAAAACATTTTGCCTATTTCGCTAACAGTTTGGTTTTTAATGGCTGTGGTATTTGAGTGAGGCAACTCTGGGGCATTTGTTATGAAGAATTCTATTTCTTACTGAAGAACAAATTATTAATATTGGATGAGTATTTCAACAGTGTGACTAATGTTTGAAATTATTTTTTCTAAGAGTTTTTCTATAACCTTCCAAAAGTCGTGATGTTTGTAGTTACTATAAATCAAGCTTTGGAAGTCCAAAAAGAATAAAAGACTGCCTTCCTTTTAGAAAAAAATGCAATTTTCTGGCCACAAGGGCATAGTGCAGTTCACTTACGTGTTGATGTAGTTTATAATCAGACGCCTTTTCTCTTCTGCAAAAGGTACTGTTAAGTAAACCAGATTTTCTAAATAGGCATTCTTAAAATTTCAGACTTACAAAGCTAGTAGTAGAATTTTATTGAAAGGCCTAGGTATTAATTTTTTAAATGAGTGCTTTAACTTAAAACAGGCGTTTGGAATAGCTGCTGCAATGTAGTCTTGTGTGTGATTTTTTTTTAAGTTGATGTGCAGTCTAATTGTTGTTTCATAAAAGTTGGATCTGTTCCTATGCCCAGGATGATTTTGTGAACCGTGAAGTACGTGAGACTAGAAGACGCCCAAACAAGTCAGATAATAGTAACTACAATGGTTGCTGATGTTGAGATTATTGTTGAACTATAATTAATAATTTGGATGGCAGAATTTATCTCTTTTTTGTAAACTCTCATAACTGAATTGCTTAAGTATAATTTATAGAATTTCAGTGCAGTTCATTCTTAATGGAAAATCTGAAACCTAAATTGCAGATTTAAAAGGTACTGTACAACCATTATATCTGTAAATAACTTAGCACCTTTTTGTCACTTAGAATAATATGTACTACTACTTGAGTGAGCGCTTTTGGAAGTTATATCAAGTTCTAGTGTTTGCTTCTTAGTAACTGAACTGAATTTACAGTTCTGTCCTAGACATTTTGCACTAAAGTAGCCGAATCCACTCTCATGTCTTTTCGTTAATGTGCTCTGTACCACTGGTGAGTGCTCCATAGTTTCCTTACCTGCTGCTACAGAATGTTATTTTACATCCCTATGGCTATTGCCAAGGCTACAAAAAAGGAAAGCTATATTTGTATGCAACACTAACCTTTTGACTGCTAATGTATGTTTCTGCTTGCTGTGCCTTGTTATGGCTGCTTTTTTTGTGCTAATAAAGTATGTTTGGTGTTCTCCTTGTATATCTGCTGTTTTATACATTTGCAACAATTTCTCTTGTAAATGGAATGGTTTGGGGTTTTTAAATAAGCATTAACTAACAACCTTTCTATAGTTAATGCAGAGTTAATGAACAGTCTAATATTGACTTATCAGAATAAGCTAACTCTAAATTTAATGCTCTACATCTTATCAGTCATAATTATATATACTGTGGAACAGTATCTGTAGTTACTGCAAATTACTGTACAGTTTAGGTTATAACAGAAAACTGACAGAGAAGTAATAAACCTATTGATTTCTCTGCTTATAAATGAAAGATTGAAACTATCCAATGACATATTATAGTAAATGAGTATCTGTAACCTCCCACTGCATCAGAAGCAGGTTAAATGAAGTCTTGTGAATTTGTAATAGATCAGTACCATTTATTGGTTTGGGGACCATCTTAATTAAAAATAAATGCCCAAAATGTAGAACTTTAACCAAAGACTTGTCCCTTTTAAAGCAAAATGGGGATTGAAGGGACTTATAATTTCTGTTGTTTCTAATTAAAGTCCCTGAAGATCATATACCAAAGTGTTTGAGAACTTCATCCAAACCTACTTTAAAGCATTATGTGCAATTAAGTTGTTATGACATAATTATATTGCCTAATTGTTGGGTCTTTTTTCTTGAGCTTATAATGTACCTGGAAAATAAACCTCTTGAGAAAAAGAAAAGTTCATACTGATTATTGGAAAAGGACTATATATGTGAGCAAGATTGTGTTTTAGAGAGGAAACTTGAAACTCCAAGAAAGCACTTGATGTTTTTATATGCTTGTAGCAAATTGATGTTCTAACTGTAGTTTTATAGAAAGTATTAATGCTTTTATGTATTTCAAAACTTTCATATGTTAAATGGAAATTGTTTTAAATGTGTTTGAGTTTATGTAAGCATGTATACACTGTGCTAAAAGTCACATGTTTCAGTTTGTGTATAATATTAATATGCAATTTTTGGTTTAAATTTTTGTCTTAAAATATTAGTGGCTTACATTTTAAAAAAGAAAAATCACCAGCATGAACTTGCACCTAAGTCTATATTCACTGTGTCCTTTTCTGAATCCCATTGTAGCCTGTCAACTAAATTTGAGTGTTAACGGTCTTTTTAAAGTGCATTTAAATACAAACCAGGAATTTCTTTAGAAGTTGAGATACATCTTTATAGTTGAAATAATTAACCCAAGAAAAGGTTGCTTTGATTTGTACCCATTCTCATTCATTTTCTTCATTCCCTTACACACACACACACACCTCTCCCTTCCGCatacatataagtgtgtattatatatttatgtatgcacatatatacatttatGTTGTTAATATTACTTTAGATGGCATTTCCACCTGATACAAAAACATTTAGAGATCTTATTCTATAGATATTACCTAAAGAGTATTCTTGTACTATTCGAATTTTATTATCTGCACTAAAAGTTTAGCCTTGCTACTTTAGCCTTGTTTATAATACAGTCACCTTACAAAGAGAAA

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