Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name ZNF705DP1
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Plot displaying the genomic locations of a retrocopy (in chr4) and its respective parental gene (in chr8). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr4:102461210-102462621  UCSC
Coordinates (T2T) chr4:105774977-105776388  UCSC
Coordinates (hg19) chr4:103382367-103383778  UCSC
Strand +
Parental Sequence NM_001039615.3_2
Parental seq. overlap 1294 bp
Parental seq. overlap (%) 35.1%
Genomic Region Intergenic
Retrocopy Summary ZNF705DP1, located on chr4:102461210-102462621, is a retrocopy of the parental gene ZNF705D. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name ZNF705D
Full Name zinc finger protein 705D
Also known as ZNF705C
Coordinate chr8:12089338-12115516
Strand +
Gene summary Predicted to enable DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. [provided by Alliance of Genome Resources, Apr 2022]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes ZNF705AP1
Bonobo Pan paniscus LOC100982111P1
Gorilla Gorilla gorilla LOC101128182P1
Orangutan Pongo abelii LOC100432405P1
Gibbon Nomascus leucogenys LOC100580152P1
Crab-eating macaque Macaca fascicularis ZNF705DP1
Rhesus Macaca mulatta LOC719571P1
Baboon Papio anubis LOC101005863P1
Golden snub-nosed monkey Rhinopithecus roxellana LOC104664164P1
Sloth Choloepus didactylus LOC119539563P5
Green monkey Chlorocebus sabaeus Without Homology
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

The Genotype-Tissue Expression project - (GTEx)

Massive Mining of Publicly Available RNA-seq Data from Human and Mouse - (ARCHS4)

Related Sequence

>ZNF705DP1
AAAATCCAGAAGAAGACAGAGAGAAACTGAGCTCTTGACAATGCATTCACTAAAGAAAGTGACCTTTGAAGATGTAGCTATTGACTTCGCCCAGAAGAGTGGAGCTTTCTCTTGATGGACATATCCAAGAGAAAGCTGTACAGAGATGTGATGCTGGAAAACATCAGTCACCTGGTGTCCCTCGGGCATCAGATAAGCAAATCCTATATAATTTTGTAGCTGGAACAAAGAAAAGAGCTATGGAGGGAAGGAAGAGAATTTCTTCAAGGCCAGAGTCCAGACAGGGAAACTGCCCTTAAGAAAAAACACATGATATCCATGCATCCTATCATCAGAAAAGACTCATCCACCAGTTTGACAATGGAGAAATCTCTCATTCCAGAGGATCCCTTTGAACATAATGATTTGGGAGAAGATTGCACTCACAGTTCCACAATGACTCCATGTTTGTTAACTCACAGTGGAAAGAAACCCTACATCAGCAAACAGTGTGGAAAATCCTTTAGTAATCAGTTGTCCCCTAAACAACATAAATTCATACTAAAGGTAAGTCATATCAACGTAATCTATGTGAAAAGGCTTATACTAATCGCTTTCACCTTAGGCAGCACAAGTTGACTCACACTGGAGAGAGACCATATGCATGTCATCTATGTGCAAAAGCCTTCATTCAGTGTTCTCACCTTAGAAGACATGAGAAAACTCACATGGGAGAGAGACCACATAAGTGTCATCAGTGTGGGAAAGCCTATATTCAATCCTTAAACCTTCAAAGACATTAGAGAACTTACCTTGGAAAGAGATGTTATGAATGTGATAAAGGTGGGAAAGCCTTTAGTCAGAGCTCTGGCTTTAGAGAGCATAAAAAAAATCACACTGGAGAGAAACTACATGTATGTCTTCTATGTGGGAAAGCCTTCAGTCTATCTTCTGACCTTAGATGACATGAGAGAACATGCACTGGAGAAAAGCCATTTGAATGCCATTTATGTGTGAAAGACTTCAGTCAATGTACTAATCTTAAATAGCATGAGAAAATTCACCCTAGAGAGAAAATTATAAACATCTTCAGAACATATTCTGACTTTAGATGACATGGTGTTAGGAATGACGAATGTAAGGAATGTGGAAGAGACTTCAGCTATAGTTGTAACATCTAAACATGCCAAAGGACTCAAATCTTGAGGAAATACTGTAATCAACATGGAGTATACTTCGGTTACGTTTATTCTTCAGTCCACATCAATGAATGGAAGAGAAATTGTATGGCATGTATGTAGCAAAGACTTGTTAGTGATCTGATCATAAACGACATGAGAGAGCTGAAACTGTCAACATAATAAACTAAAAGTCTTAAGCAACAGCTTTGACTTAAAACATGTGGGACTTTCAGGTAGAGAATCTCTAGCTC
>NM_001039615.3_2
ctgtgggaagtttgttctttcgctttttgcaacatagcttgctgctgctcactctttggtttcgtgccgcctttaagcgctgtaacactcactgcgaaggtctgcaacttcacttctgaggccagccagaccatgaacccactgggaggaataagcaactctggacacaccatctttaagaattgttaacactcaccaggagggtctgcggcttcattcttaaactcagcgagaccaagaacccaccaattccggacactgtggagagggaccagtggtgggcagggctccagaactccaaagatcATTTTCTCAAGCAATTTTTAAATTTCATTCTTTTACCCTATTGAGCTTTTCTTAGTGCCTAAAGTGTCTGCAAGTGGAAATCCAGAGGAAGACAGAGAGAAACTGAGTTCCTGACAATGCATTCACTAGAGAAAGTGACTTTTGAAGATGTAGCTATTGACTTCACCCAGGAAGAGTGGGACATGATGGACACATCCAAGAGAAAGCTGTACAGAGATGTGATGCTGGAAAATATCAGTCACCTGGTGTCCCTCGGGTACCAGATAAGCAAATCCTATATAATTTTGCAGCTGGAGCAAGGAAAAGAGCTGTGGCGGGAAGGAAGAGTATTTCTTCAAGACCAGAATCCAGACAGGGAAAGTGCCCTTAAGAAAAAACACATGATATCCATGCATCCTATCATCAGAAAAGACGCATCCACCAGTATGACAATGGAGAACTCTCTCATTCTGGAGGATCCTTTTGAATATAATGATTCGGGAGAAGATTGCACTCACAGTTCCACAATAACTCAGTGTTTGTTAACTCACAGTGGAAAGAAACCCTGTGTCAGCAAACAGTGTGGAAAATCCCTTCGTAATCTTTTGTCCCCTAAACCACGTAAACAAATTCATACTAAAGGTAAATCATATCAATGTAATCTATGTGAAAAGGCCTATACTAATTGCTTTTACCTTAGACGGCACAAGATGACTCACACTGGAGAGAGGCCATATGCATGTCATCTATGTGGAAAAGCCTTCACTCAGTGTTCTCACCTTAGAAGACATGAGAAAACTCACACGGGAGAGAGACCATATAAGTGTCATCAATGTGGGAAAGCCTTTATTCAATCCTTTAACCTTCGAAGACATGAGAGAACTCACCTTGGACAAAAGTGTTATGAATGTGATAAAAGTGGGAAAGCCTTTAGTCAAAGCTCTGGCTTTAGAGGAAACAAAATAATTCACATTGGAGAGAAACCACATGCTTGTCTTCTATGTGGGAAGGCCTTCAGTCTGTCCTCCGACCTTAGATGACATGAGAGAACACGCACTGGAGAAAAGCCATATGAATGCCATTTATGTGGGAAAGCCTTCAGTCAATGTACTAATCTTAAAAAGCATCAGAAAATTCACCCTGGAGAGAAAATTATAAACTTCTTCAGAACATATTCTGACTTTAGATGACACAGTGTTAGGAATGACGAAGGTAAGGAATGTGGAAGAGACTTCAGCTGTAGTTGTAGCATCTAAACATGCCAAAGGACTCACATTTTGAAGAAATACTGTAATCAACATGGAAGATACTTCAGTTGCCTTTATTCTTCAGCCCACATCAATAAATTCATATGGAAGAGAAATTGTATGACATGTATGTACCAAAGACTTGTTAGTGATCTGAGCATAAATGACATGAGAGAGCTGAAACTGTCAGCATAATCAACTAAAAGTCTTCAGCAACAGCTTTAACTTAAAACATGTGGGACTTTCAGGTAGAGAATCTCTAACTCTGCATTCAGTGTGAAAATGTTTTTATTTGCAATTTATTGTCAAATAACATGAGAAAACTTTACTTGGATGAACCCTTTATTTGTATTTTTCTGTGAATGAACATTCAGCCAAGCACCAGGCTTGATGTTCACAAGAGAAGAGTGACAAAATGCTGCTAAAATGGAAAATAAGAGAGGAAAGCCTTCATAAGCTAAATAACAAGGGAAAGTCTTTCCAAGGGCAATGAATTCTCTTGGAATACCAAATACTTCTTACTGGAGAAGTTATGCAATGAAAAATCATGAGAAATCCTTTCTTCATAGAGCAACACATGTGGCACATGTGAGATTTCACACTGGACAAAACAGGGTTAGCATCTTGAAAGAAGAAAATTCTTTAGTGGTAATTCATTTCTTAGTTGACATTAAGTTTCTCACGTTGAGGAGCTATCAAACTTGAAAATCACTGTGGAGAAACCTGATAGATTTCTCATCAGAAAAGTGAGTCAAGAAGGTGGACCTCTAGAAAAAACTCTTAACACATACTTTAGCAAAATAATTCAGAAATTTGAGAAAATATCTATTCATAAAAATGTGGCATGTAAATGCATAATAGCAAAGTGACCAAGGAATAAATTGAATGCAGAATTATATAAGAAATCTCATTAAACTTTTCCAAAAGACCAATACTTACAAATATTGAAAGAATACAATCTGTTGTTGAAAAAACTTAGTATGTTGGTGAAGCCCTTGTTTCATTTATGCAGCCCTAACAAACTGATTTGCATCTGAACTCCTTGGGTGAGATTCTTGGTGGAGATTCTACCCCAACTTCTGAGTCTCCCCAGTCTTCAACAGCTCTTTCCTCACAGCTCACCTCCCTTTACTTCAACGTCCACCAAAACCACTTGTTTCCATCCAACCCTCGAGTTGACACACCAGGGATCTTCAGCCCCACTTGCTAGATTTCTCAGTTTGTCATTGCATAGATTTAGCAGGGAAATGGAGGCTGTATCAAAGACCCCTAGTATATGCATTTGGGTGTCCCCAGCTCTTGCCTCTGTCTCTGAGCAGTTACCTGGGATCAGAGAATAAGGCAGCTCTTCTCTTCTATCCCTCAGAAGGCTCTTGAAATTTTGTCCCTGGAGCCTCTCTAACTGGAAGTAGCAGTTCATCTCATGACACCCCACATTTTATTCAGGTGAGTCCTGAGTTATTACACAGAGACAGACACAGCTGTGCTCCTTTTACTGCAGTCCAGAAGATAAAACACCAGCATGATAAAACAGCCGAACCTGTCAGCCACCTTGCAAGCCTTTTCTATATTTGATTCAATGTACTTTTCCCGAAGCAAAATGAAAGTTCTCACAGAGGGGCCCTCCTCTGCCTTGTCCTCAGAATTGGAAAATGTATTGTCCGTGAAGGAGCCTCACCACTGAACCTAAAACTCAAGAGAAAATGTTTCCTGAATATCAAGTGGGATGACTTGAAATTTTGTCAAACAGGCAGAATCTTAATACGATCGGCCTTACTAAGGCTAAATGGCCTTATCCATGGTTGAAATTGACACATCATCATATTAAAAAATCTCCACGAGTGATTGATTTTACTCTGCAGCCAGGGTTTATGTCAAGTGTGAGGATAATGAGCAAGAAATTCAAGCCCTTGGCAAACTGGTTGGAGAGGCAAGGACTGTGTCCAGGCAGAGCTCATATCAttatttattgtttaatctatttaattaaatatgtaatttaCCCACAAACTGTGGCTGACATTATATGTACTCCTGAGCCacattaagatgtactatttgtgctgtgaaattctatgggatttgacaaatgcatggtggcagatctccagcgattattaaagcgtaacacagaatgcttctctTATTCAA

Publications

PMID - Link Title
No publications available for this retrocopy