Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

Advanced Search

Summary

Retrocopy Name CKS1BP5
Plot displaying the genomic locations of a retrocopy (in chr5) and its respective parental gene (in chr1). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr5:144439142-144439950  UCSC
Coordinates (T2T) chr5:144971333-144972141  UCSC
Coordinates (hg19) chr5:143818705-143819513  UCSC
Strand +
Parental Sequence NM_001826.3
Parental seq. overlap 697 bp
Parental seq. overlap (%) 85.6%
Genomic Region Intragenic (KCTD16)
Retrocopy Summary CKS1BP5, located on chr5:144439142-144439950, is a retrocopy of the parental gene CKS1B. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name CKS1B
Full Name CDC28 protein kinase regulatory subunit 1B
Also known as CKS1|PNAS-16|PNAS-18|ckshs1
Coordinate chr1:154974681-154979251
Strand +
Gene summary CKS1B protein binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. The CKS1B mRNA is found to be expressed in different patterns through the cell cycle in HeLa cells, which reflects a specialized role for the encoded protein. At least two transcript variants have been identified for this gene, and it appears that only one of them encodes a protein. [provided by RefSeq, Sep 2008]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes CKS1BP1
Bonobo Pan paniscus CKS1BP1
Gorilla Gorilla gorilla CKS1BP1
Orangutan Pongo abelii CKS1BP1
Gibbon Nomascus leucogenys CKS1BP1
Green monkey Chlorocebus sabaeus CKS1BP8
Crab-eating macaque Macaca fascicularis CKS1BP2
Rhesus Macaca mulatta CKS1BP2
Baboon Papio anubis CKS1BP2
Golden snub-nosed monkey Rhinopithecus roxellana CKS1BP1
Marmoset Callithrix jacchus CKS1BP3
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>CKS1BP5
GGTGCTGCTGGGAGTTGCTTGGATGTTGGCGGTGTGGGGCTGAAAGCTTGCAGACACAGCGATCATATCGCATAAATAAATTTACTATTTGGAGAAATACAATGATGAGGGGTTTGAGTATTGGCATGTCATGTTGCCCAAGGACATAGCCAAGCTGGTCCCTAAAACCCACTTGAATTGAATGGAGGAATCTTGGAGTTCAGCAGAGTATGAATCTGAATGGAGGAATCTTGGCATTCAGCAGAGTCAGGGATGAGTCCATTATATGAACCATGAACCAGAGCCTCACATCTTACTATTCCAGTGCCCGCTACCCAAGAAGCCAGATGGTAAATGAAGTTGGCAAGTCACCTTCCAGCCTCGAGCTTTACACAGCTGTCCTTGCTTCCTAACATCTTTCTGATAACACTATTATTTTGCCTTCTTGTTTCTCACTTTGATATTTAAAAGATGTTCAACACGCTTTTTGAATGTGCTGGTAACAGTTTTGCTTCTTCAGTAGAGCCACCACCACCACAGCCCAGAGAGATGAGTGCTCTGTGGGCCACAGCCTCAGCTGAGTGTGACCCCAGAAGCCATGGTGTGCTCTGTATCCAGAACACACTTGGTAGCTGGAAGAAGCGTCTGAGATTAAGATCATGGCTGTTACAGGTATCGTGTAAACTTGCTGTTTTTGTTTTTTTCCTGCCGGGTGTTGTATGTATGGTGACTTGTGGATTTATGATTCAATATATTGGAAACTTTCCATATTATTCAAGAAGTCTGTTCATGTTAAAATCCTTGATTAAAGAGAAAGTTTTCATAATCTA
>NM_001826.3
GCGTGCTGTTGGGAGTTGCTTGGAGGTTGGCGGCGCGGGGCTGAAGGCTAGCAAACCGAGCGATCATGTCGCACAAACAAATTTACTATTCGGACAAATACGACGACGAGGAGTTTGAGTATCGACATGTCATGCTGCCCAAGGACATAGCCAAGCTGGTCCCTAAAACCCATCTGATGTCTGAATCTGAATGGAGGAATCTTGGCGTTCAGCAGAGTCAGGGATGGGTCCATTATATGATCCATGAACCAGAACCTCACATCTTGCTGTTCCGGCGCCCACTACCCAAGAAACCAAAGAAATGAAGCTGGCAAGCTACTTTTCAGCCTCAAGCTTTACACAGCTGTCCTTACTTCCTAACATCTTTCTGATAACATTATTATGTTGCCTTCTTGTTTCTCACTTTGATATTTAAAAGATGTTCAATACACTGTTTGAATGTGCTGGTAACTGCTTTGCTTCTTGAGTAGAGCCACCACCACCATAGCCCAGCCAGATGAGTGCTCTGTGGACCCACAGCCTAAGCTGAGTGTGACCCCAGAAGCCACGATGTGCTCTGTATCCAGAACACACTTGGCAGATGGAGGAAGCATCTGAGTTTGAGACCATGGCTGTTACAGGGATCATGTAAACTTGCTGTTTTTGTTTTTTCCTGCCGGGTGTTGTATGTGTGGTGACTTGCGGATTTATGTTTCAGTGTACTGGAAACTTTCCATTTTATTCAAGAAATCTGTTCATGTTAAAAGCCTTGATTAAAGAGGAAGTTTTTATAATCTAGT

Publications

PMID - Link Title