Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name NR2F6P1
Plot displaying the genomic locations of a retrocopy (in chr5) and its respective parental gene (in chr19). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr5:93585278-93585479  UCSC
Coordinates (T2T) chr5:94069341-94069542  UCSC
Coordinates (hg19) chr5:92920984-92921185  UCSC
Strand +
Parental Sequence NM_005234.4
Parental seq. overlap 168 bp
Parental seq. overlap (%) 7%
Genomic Region Intragenic (NR2F1)
Retrocopy Summary NR2F6P1, located on chr5:93585278-93585479, is a retrocopy of the parental gene NR2F6. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name NR2F6
Full Name nuclear receptor subfamily 2 group F member 6
Also known as EAR-2|EAR2|ERBAL2
Coordinate chr19:17231883-17245919
Strand -
Gene summary Enables DNA-binding transcription factor activity and sequence-specific double-stranded DNA binding activity. Involved in negative regulation of transcription by RNA polymerase II. Located in nucleus. [provided by Alliance of Genome Resources, Apr 2022]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes NR2F6P1
Bonobo Pan paniscus NR2F6P1
Gorilla Gorilla gorilla NR2F6P1
Orangutan Pongo abelii NR2F6P1
Golden snub-nosed monkey Rhinopithecus roxellana NR2F6P1
Marmoset Callithrix jacchus NR2F6P1
Mouse lemur Microcebus murinus NR2F6P2
Mouse Mus musculus Nr2f6P2
Rat Rattus norvegicus Nr2f6P2
Chinese hamster Cricetulus griseus Nr2f6_1P1
Pig Sus scrofa NR2F6P1
Sheep Ovis aries NR2F6P1
Dolphin Tursiops truncatus NR2F6P2
Horse Equus caballus NR2F6P2
Dog Canis familiaris NR2F6P1
Panda Ailuropoda melanoleuca NR2F6P1
Chicken Gallus gallus NR2F6P1
Budgerigar Melopsittacus undulatus LOC101874725P1
Gibbon Nomascus leucogenys Without Homology
Green monkey Chlorocebus sabaeus Without Homology
Crab-eating macaque Macaca fascicularis Without Homology
Rhesus Macaca mulatta Without Homology
Baboon Papio anubis Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Cow Bos taurus Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>NR2F6P1
GTGCGTGGTGTGCGGGGACAAGTCGAGCGGCAAGCACTACGGCCAATTCACCTGCGAGGGCTGCAAAAGTTTCTTCAAGAGGAGCGTCCGCAGGAACTTAACTTACACATGCCGTGCCAACAGGAACTGTCCCATCGACCAGCACCACCGCAACCAGTGCCAATACTGCCGCCTCAAGAAGTGCCTCAAAGTGGGCATGAGG
>NM_005234.4
AAACCGGCCGCAGCGCGAGGCCGGCGCGCGGGGTCGGTGGCGGTGGCGGCGGCGAGAGCGAGGCTTGGGCCCAGGCGCAGGCCCAGGCCAGGCAGGAGCGGCCGCAGCGGGGGCGGCAGCTCCAGAGGCGCCGGCCCAGCGGCCCTGCAGGCCCGGAGCGGCAGCCGCGGGCGCCGGGGGACCCAGGGGGCGCGGCGATCAgccccggcgcgcacccgccgcccctccccccccgccacgggcggccgcgcAACTTGCGGCCAAACTTTCCCCCCGGCCTCCCGCGCTCGGATGGCGGCCCGCTGAGTTGGCCGCAGCCCCCGGGCGAGCGGCGGCCAGGCCAGAGGACGCCCCCTGCGCGGCTCGGGCCGGGCCATGGCCCGCGCGCCCCCGCCGGGGCCCCAGGGCGGCGGGACGCGAGTCCTCTGGGCCCCCGGCCCGCGCCTCTAGCGTGCCCCTCCCGGCCCCGGGCCCGGCCCCGCGCACGCGTGGGAAAGTTGGCCTGGAACCGGCCCGACCAGTTCCGCCCGGGCGCGAGGACCGGCCGCAGGAAGTTGCTGCAAAACTTTTTTGGGGGGTGCAGCCCGTGCCCCCCGCGCGCCGGGGCCGAATGCGCGCCGCGTAGGGTCCCCCGGGCCGAGAGGGGTGCCCGGAGGGAAGAGCGCGGTGGGGGCGCCCCGGCCCCGCTGCCCTGGGGCTATGGCCATGGTGACCGGCGGCTGGGGCGGCCCCGGCGGCGACACGAACGGCGTGGACAAGGCGGGCGGCTACCCGCGCGCGGCCGAGGACGACTCGGCCTCGCCCCCCGGTGCCGCCAGCGACGCCGAGCCGGGCGACGAGGAGCGGCCGGGGCTGCAGGTGGACTGCGTGGTGTGCGGGGACAAGTCGAGCGGCAAGCATTACGGTGTCTTCACCTGCGAGGGCTGCAAGAGCTTTTTCAAGCGAAGCATCCGCCGCAACCTCAGCTACACCTGCCGGTCCAACCGTGACTGCCAGATCGACCAGCACCACCGGAACCAGTGCCAGTACTGCCGTCTCAAGAAGTGCTTCCGGGTGGGCATGAGGAAGGAGGCGGTGCAGCGCGGCCGCATCCCGCACTCGCTGCCTGGTGCCGTGGCCGCCTCCTCGGGCAGCCCCCCGGGCTCGGCGCTGGCGGCAGTGGCGAGCGGCGGAGACCTCTTCCCGGGGCAGCCGGTGTCCGAACTGATCGCGCAGCTGCTGCGCGCTGAGCCCTACCCTgcggcggccggacgcttcggcgcagggggcggcgcggcgggcgcggTGCTGGGCATCGACAACGTGTGCGAGCTGGCGGCGCGGCTGCTCTTCAGCACCGTGGAGTGGGCGCGCCACGCGCCCTTCTTCCCCGAGCTGCCGGTGGCCGACCAGGTGGCGCTGCTGCGCCTGAGCTGGAGCGAGCTCTTCGTGCTGAACGCGGCGCAGGCGGCGCTGCCCCTGCACACGGCGCCGCTACTGGCCGCCGCCGGCCTCCACGCCGCGCCTATGGCCGCCGAGCGCGCCGTGGCTTTCATGGACCAGGTGCGCGCCTTCCAGGAGCAGGTGGACAAGCTGGGCCGCCTGCAGGTCGACTCGGCCGAGTATGGCTGCCTCAAGGCCATCGCGCTCTTCACGCCCGACGCCTGTGGCCTCTCAGACCCGGCCCACGTTGAGAGCCTGCAGGAGAAGGCGCAGGTGGCCCTCACCGAGTATGTGCGGGCGCAGTACCCGTCCCAGCCCCAGCGCTTCGGGCGCCTGCTGCTGCGGCTCCCCGCCCTGCGCGCGGTCCCTGCCTCCCTCATCTCCCAGCTGTTCTTCATGCGCCTGGTGGGGAAGACGCCCATTGAGACACTGATCAGAGACATGCTGCTGTCGGGGAGTACCTTCAACTGGCCCTACGGCTCGGGCCAGTGACCATGACGGGGCCACGTGTGCTGTGGCCAGGCCTGCAGACAGACCTCAAGGGACAGGGAATGCTGAGGCCTCGAGGGGCCTCCCGGGGCCCAGGACTCTGGCTTCTCTCCTCAGACTTCTATTTTTTAAAGACTGTGAAATGTTTGTCTTTTCTGTTTTTTAAATGATCATGAAACCAAAAAGAGACTGATCATCCAGGCCTCAGCCTCATCCTCCCCAGGACCCCTGTCCAGGATGGAGGGTCCAATCCTAGGACAGCCTTGTTCCTCAGCACCCCTAGCATGAACTTGTGGGATGGTGGGGTTGGCTTCCCTGGCATGATGGACAAAGGCCTGGCGTCGGCCAGAGGGGCTGCTCCAGTGGGCAGGGGTAGCTAGCGTGTGCCAGGCAGATCCTCTGGACACGTAACCTATGTCAGACACTACATGATGACTCAAGGCCAATAATAAAGACATTTCCTACCTGCACA

Publications

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