Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

Advanced Search

Summary

Retrocopy Name RTRAFP2
Plot displaying the genomic locations of a retrocopy (in chr5) and its respective parental gene (in chr14). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr5:95440055-95440815  UCSC
Coordinates (T2T) chr5:95940978-95941738  UCSC
Coordinates (hg19) chr5:94775759-94776519  UCSC
Strand +
Parental Sequence NM_016039.3
Parental seq. overlap 702 bp
Parental seq. overlap (%) 10%
Genomic Region Intragenic (FAM81B)
Retrocopy Summary RTRAFP2, located on chr5:95440055-95440815, is a retrocopy of the parental gene RTRAF. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name RTRAF
Full Name RNA transcription, translation and transport factor
Also known as C14orf166|CGI-99|CGI99|CLE|CLE7|LCRP369|RLLM1|hCLE|hCLE1
Coordinate chr14:51989546-52010694
Strand +
Gene summary Enables RNA binding activity; RNA polymerase II complex binding activity; and identical protein binding activity. Involved in negative regulation of protein kinase activity; positive regulation of transcription by RNA polymerase II; and tRNA splicing, via endonucleolytic cleavage and ligation. Located in microtubule cytoskeleton; nucleoplasm; and perinuclear region of cytoplasm. Part of tRNA-splicing ligase complex. [provided by Alliance of Genome Resources, Apr 2022]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes RTRAFP2
Bonobo Pan paniscus RTRAFP2
Gorilla Gorilla gorilla RTRAFP2
Orangutan Pongo abelii RTRAFP2
Gibbon Nomascus leucogenys RTRAFP1
Green monkey Chlorocebus sabaeus C24H14orf166P1
Crab-eating macaque Macaca fascicularis C7H14orf166P1
Rhesus Macaca mulatta RTRAFP1
Baboon Papio anubis RTRAFP1
Golden snub-nosed monkey Rhinopithecus roxellana RTRAFP1
Marmoset Callithrix jacchus RTRAFP1
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>RTRAFP2
TGTTTGGCTTGAAGACCAGAAAATTAGACACTACAAGATTGAAGACAGCTAATTTAAGAAACATCCACAGCAGAGACTGGCACAAGTTCTTTGAAAAGTGTCTCAGAGGTGCTGACAAGTCCTTTCAAGATTCAAGATCAACAAGAAGCTATTGACTGGCTTCTCGGTCTAGCTGTGAGGCTTGAATATGGAGATAATGCTGAAAAATACAAGGACTTAGTACCTGATTATGCAAAAACTGCTGACAATGCAACTAAAAATGCAGAACCATTGATCAATTTGGATGTAAATAATCCTGATGTTAAGGCTGGTGTGAAGGCTAACCTGCTTCAGATTCAATGTCATGACGATTACCTGGTAATGCCTAAGGCAATTCGAATTTTGGTTCAGGAGCACCTGACAGGATGCAGTTGCTAAGGCAAATCAAACAGAGGGTTTGCCTGTTGCTTTAGACAAAATATTATTGGTTTTGATGCAGGAGATGCAGTTCTTAATGAAGCTGCTCAAATTCTGCAATTACTGCATATAGAAGAGCTCAGAGAGCTACAGACAAAAATTAATGAAGCCATAGTAGCTGTTCAGACAATTATTACTGATCCAAGGACAGACCACAGACTGGGAAAAGTTGGAAGATGAACACTTTAGGACTTCAGCTTCTCACCTATTTAGTACAACTGGGAACCATGTCCACTTCTGGCATGTTTGAAAATCAAACGTCACATTTTGCGGGGAGGAATCCCAGAAAAGTGACTATGTTCTAG
>NM_016039.3
CTCTCGCCGCGTCGCCGGTGCCTGCGCCTCCCGCTCCACCTCGCTTCTTCTCTCCCGGCCGAGGCCCGGGGGACCAGAGCGAGAAGCGGGGACCATGTTCCGACGCAAGTTGACGGCTCTCGACTACCACAACCCCGCCGGCTTCAACTGCAAAGATGAAACAGAATTTAGAAACTTCATCGTTTGGCTTGAAGACCAGAAAATCAGGCACTACAAGATTGAAGACAGAGGGAATTTAAGAAACATCCACAGCAGCGACTGGCCCAAGTTCTTTGAAAAGTATCTCAGAGATGTTAACTGTCCTTTCAAGATTCAAGATCGACAAGAAGCTATTGACTGGCTTCTTGGTTTAGCTGTTAGACTTGAATATGGAGATAATGCTGAAAAATACAAGGATTTAGTACCTGATAATTCAAAAACTGCTGACAATGCAACTAAAAATGCAGAACCATTGATCAATTTGGATGTAAATAATCCTGATTTTAAGGCTGGTGTGATGGCTTTGGCTAACCTGCTTCAGATTCAGCGTCATGATGATTACCTGGTAATGCTTAAGGCAATTCGGATTTTGGTTCAGGAGCGCCTGACACAGGATGCAGTTGCTAAGGCAAATCAAACAAAAGAGGGCTTACCTGTTGCTTTAGACAAACATATTCTTGGTTTTGACACAGGAGATGCAGTTCTTAATGAAGCTGCTCAAATTCTGCGATTGCTGCACATAGAGGAGCTCAGAGAGCTACAGACAAAAATCAACGAAGCCATAGTAGCTGTTCAGGCAATTATTGCTGATCCAAAGACAGACCACAGACTGGGAAAAGTTGGAAGATGAACACTTGAGGACTTCAGCTTCTCACCTACTTAGTACAGTTGGGAACCATACACTTCTGGCATGTTTGGAAATCAAAATGTCACATTCTCGGGGGAGGAAGCCCAGAAAATTGGGTATGTTCTAGAGATTTACCACCATTGCTTATTGCTTTTTTCTTTAATAAAGTTTAGGAAAGTAGAATTTTTATTATGTACTGTATGTTTGCATAAATCACCTTTCTCCTTTGTGGTTAAGGCATATATGCCAACCCCCAGCTTTGTCCTAGAGACAATATAGATCCTTAAGTCATAGGAAAACTTAAAACACTTTATTGGAGTAATCTAGAAAATTTTAAAATTGTTACATCTTTGGTATTTATAAATGTGATACTTTACTTTCTGTGGGTACTTCTATAGAGGCACTACAGGATCAGAAAATGCAAATTGAATCATTTTAGCACCTTTTGATATAAATAGAAATGCACTGATGCAGAGGTAAAAAATCTTAGAACTTTTGTTGGGAAACTATAAATAATTGGTCCTTTCCCATCAGTTCTGCATTGGCTTCTCCAACTGTCAAGGTTTAGGATTATATTGTTATATTGATCACATGTGCTTTAATTTCTTGGCCAGAAGGAATCCATGGCAAAAATCAGGTTTAGAGTCTTAAACTCTAATTCTTAGTTGAATGAATTTGATCTTTTAAATATTAATGATAAATGTTTACAAGAAGTTGCTTTAATAAGCAACAGTTAAAATTCTGTTACCTTTTTAAACTTGCAATAACAACCTTCATTTTTAAAAATACAGTAGTAAAGATTGAGGTATCAGCTTTTCACAAAAGTCTTTTTGCACTACAAAATGTTCATCTTGGATGCTCAGGAACGTCTAATGGCCAATTCCTTTTTTACTTTCTTTGCCTTTGCAGTCACTGTTCTTTAGGGTCCAGGTTCTGATTGTAAACTCCAAGTCttcctttacattactgtacttactttcttCCTGTGAGAGAAGAGCAGGGGTGGGACAGGGTGGTGGGTGAGTATATTGTAACCAAGTTGCAACAGCAAGTCTTTGCATTTTGTGTATAAACTAGGTAGATTTAAGGTAGTAAAGACTGGCCCTCAGGGCAGGAAGAAGGCAATGGTGGCAGTGTCACAGGCAGCAGGGGTAATCAAATACCATATATATCCCTTCTCTACCCTGCTAATTTAAAGGAGCATCCTAAAGCATACTTTTTACCTGTTGGGCAGTAGGGGTAGACTGCAGTTATCCCGTAGAGGTGAGATCGTTGTTCTGGGAGATACTCATCAGTAAACTGGCCACTATGTTTATTTACTGATACAACACCATCCCTGGTAACAGAAAGGAAGAGTGAATTCAGGGACAGTCATTTACTAGATAAAGAAGTCAGTCAGCCACAGAAAATCAGTTGCAATAGAGGAAAATTTCTGGCAGCCTTCTCTGTCCCAGGGCTGGTGCTAAAGCCATACTGAAGTTTGAAGACCATTGCTCTAAATCCATTGctcatctctagctgcatgttagaatcacatgatgagctatcaaaTCAGAGTTGTAGGGCATGGTGTAAAGGGCTTAGACTTTAATGTTCCACAGTTCCTCATTTGAGAACTAGTCTAAATAGTATTTTTCGGTCCCTCAGACAATATGTCCACAGTGTCAAAAGCCAACTTAAGCCCTGTAATATAGCTCATGGTATCAAGGGTAGTCTTATTCTCTAAAGAACATATTTAGATTAATATGCTCCCTTTTGAGACATTATCCAATAGCTTTGCTACTTTTTAAGCTATATGTGAGCAATACCATTCGATTTCTGGGTGAAGTAAAAGGATGATTTCAAAAACATGAAAGGATGAAAAACATCCTTGAAGGATCTTATCTGCCAATGAGGAGGTGATGAAACAAAAGCCTCAGAGGGCTTAATGAGTCAAGTCAGGTACTGACTTTTGGTAAAACAAGTGGTGTGTCCTCTGGAACAGTTGGCCTTTTCAGGCTTGTCCAGAATTTGTGGGGCTCACCTCCTCCAGTCTGTGTGGTAGAAGTGATCTGCATAGCTTACGATGCTGAAGGGGTACTTGAGGTTGTTTTGAATGACACGCCGTCCAGTTCCATCAGGTAGTGTACACTCCAGTTTTTTGGTTCCTTTTAAAACAAAGGGGGAAAATGAGGTCCTTCAGCTGCTTTGCCAAAAATGATAGTGACATAGTGATAGTGACACAGTGATAGAATGGGGAAATAGGATATTTTACTTCCATTACAGTCATAGATTAGCAACTGTAAAATTACCTGTCCTATTACTAGTCTCCAGTTTTTAGTAGAGATTCAAACTTTCAATCCTTTTTTGGAAGACAGGATTGCATTTACTGAAATCTGGTAAGTTTCTGCCAAAGTAGGGCATTAAACATAATTATTTTTATAATTTGTGTGATTTCAAGCCTTAGCTTATAAATTATAACATCTGGGTAAATACTTGCCCTTTGTAAGCTATGTCTATAATTACTGAGGCAACCTTTTAACCAAAATCCTTAGTATTTTTAAAATATTTTCTAGGTAGGAGGAAAAAAGTGACTAAAATGGTAACATAACTCATATTTCAATGTAAAGGAATCAGTCTTAAAAATTTTTACAATAGCTAAACCATTCAAGAATTTCCAAGTTTCACATTTCTCATGGAGCCGATTTAAATTTCAAATCCTTTTAAGAAATGTAACTTGTTTTAAACAACTGGGTTATAAAAGTGACCTATGTACATTAGGCCCTTTTATTAGATTACAAATTCAAGAACAGTCTTTTTCATATTCTTTAGTATAGAACTAGACACACAGCATTTTTTCAGTTGTGCTGATAAAAGCAAACAAATGTAGGTTGCTAATACCCATGTTATTACTGAAGGAAGCTACCCTGCTACAATGCTTTCCAAAGAATGTCCTTAGCATTATAACAGATGTTTATAGGTAAGTTATAGTGACCCTCTCCCCGCATAAGAATAACTTCACTTAAGTTTGTCAATTCAACAATGGCTAATTCTTTTAACTGTTAAAAATATGCCAGGCACTCATGGTCAGGCAAGCAGTACAAACTTACTGCTTGATATATCCTTCCCTCCACCCAAACCCCAGAAAGTTCATTTTAAGACTCATTTACTAGTACTTAAATTTACTAGTACTTAAAAGTTTACAGACCAAAGAAAGGAGATCTAAGTGATGGGATTTCATTTTGTAGTAAAATCTGTTAGTGCTCACATTCACTGTGATGAGAGGTTATCTATTTGCATTCCATCAGTAGTATTACCTGCATCTGCCCAGCAGAGCAGTTTAGAGAAAGGGTCAAAGGTTAAGCCATTGGGCAATCCAATGTCTGTATTGATCAGAATTCTTCTGTTTTCTCCATCTAAAGATGACGTTTCAATTTTAGGAGCTTCTCTATTCCAGTCTGTCCAGTACAAGTTGCTGTAAGTTAAAAATCAAGATTGTAAAAGAATAGCCATGTAGCCtgtggtaggcagcatctaagcagcccccagtgatctccatctcctcatgtattatagccttaagcaatccccttgagtttgggctgcattagtagtgtcttgcttcttctagtgcatagagtatagcagaagtgataggctatcactgccgatattcggtctcaaaaaactggtttctgccttaggggctctctcttgctccctttgagggaagctggatgccatgttgcaagctaccctgtaaaggggaacatgtgccaaggaactgatgtccttgagggctgttggccagagacattagtcttgcctgtagcccatgtgagcatgcttgggctgtgtcttccccgagctgagccttgtgatcactgcagtttggccattacctgattgcagccttgtgagagactccatgcctgagggagctcggtgaagacacacttggattcctgactcacagaaactgtgagactaaatgttatcttacactgctgagggtttgggcaatttcttacacagcagtaggtaactaatacaCAGCCATATTCCACTTTTACCTGTATCACAAGGTTTTCTGATTATTGTCACTATGTGGGAGAAGTCATTACTAAGTTACTATCAGAATCCCTGCCTCCAAGATACCCCTTGACTCAACTGCCCCAAAACCCTCCGTTTGTTGAAGTCTTGAATTGGATCTTGGGTTTTAGAATAGAAACAAATACAGCTGTTAGGAATGGCTTCGATACAAACTATGGAACTTGAAGAGATGTGGACCAGGGATTTGAGAAGGAAACTGTTCTTTCTTCTGCCAAAAATACAATTTGGTACTTGAAGGGGTACCTGGCACCCAGGGATGGAAACATTTTAAGTTAAGCACTTTACCTTTTAAATGCCACGTTAAAAATGAAATATATTCATAACAGATACTAACGAGGAAATATGGTCCTATTAAGTGGAAATAGGTTATAAGGAAACAAACAGGTTTATCGTTAGAGCAGAAATAATGTTGAAAGCACTTTTTATAAAATACTATTTTATAAAAGCTATAGAAGCTTTGAATAAATCAGTTGGGCTACAGAGAACCTCAGTGAGAGGAGAGGAAGAAACCATAGGTTTCCCCTGTTGCGAATTTCATCCCTTATGCCCAACAGATGAAGCAGAGAGAAGCTGAGAGCAAAAGCTAGAAAGCAGTTTCCACTTTGCGCTAAGGTGGAGGTGGCCAGAGGGTACAGCATGCATATCATTGCTTCATCGCTTCTGATCAGTCTCCTCCCCAAAATGATTTAATATCATCAACAACAATAAGTCTGAAACAAGCTCACACAGATATTTGGTGTAAATTATTTGGGGATTGCCAGAGGAAGAAAGTTGTAAAGGTGAAATCTATAGAAAGCAAATGAGAAATATGCAGGAAGGCTTGACAACCATTCTGTTACGCAGTTGAAGGAGATGTAATTACATGTGTTATATTGCAACCTGGTTCAAGGTGGGTTTTCTTTTTATTAAAAATTCAAGTCCTTTAGCATTTATATTTGCTGTCTGGATAAGAAAGTTCTACTTTCATATTTAAACTCATGGCTGTGATGTGGATTTCAGCTTAAAAGTATGCTTTTTCCCCAGACTCCAGAGACATGGCCAAAGTTTCATTGCCTACAAGATGGCAGCTCTCCCCAGTTTTCAGGTCAAGCACCAAGAAGGAATAAGGggccgggcgcagtggctcatacctataatcccagcactttgggaggccaaggcaggtggatcacccagggtcaggagttggagaccaaaatggcgaaaccctgtctcgactaaaaatacaaaaattagctgggcatggtggcacatgcctgtagtcccagctacttgggaggctgaggcaggagaattgcttgaacccgggagatggaggttgtagtcagccgagactgtgccactgcaccccagcctcggcaacaaagcaagaccttgtctcaaaaaaaagaaaaaaaaaagaaaaaaGGACCTTCCAAATGTCCAAATGTCAGAAAGGCAAGCCTATGCAAAGAGTTTTTAAGAGGGCTATTAATTCCTGTTAAGTCAACTGGAATAGAGAAGGATACAGGTACTTTTCCTGTGTGTAGAACCCAAAGTTTGAAACCACCTTTGAGGCACTGCACTAAGTATTTCATAGTCAAAAAGCACTTACCTGAAAATTAAAGCTGAAGGTTTTCTTTACTGATTTGAAGGGCATCTGGGAATTTCATTTCGTAGAAACTCCACTTAAACATGGCAAGAGTTTCTCAAGATATAAAAATTCTCCCTGATTGTAACAAGTACTGAGACAGTGAACAAATCCTGTATGTCACATTTGATGACCTTAGCAATTATACAGACAGGGAAAATGTTTATCTTGATTTCTGCTACAGCAACACTGAAGCCAGAGGTGTCTGAGCTTTGGCTAATGTCACTTGATGTAGGTCAGCCCTACTGTGAGCGTCAACCCTGGTTTCTAAATGTGCTGCTGGAGGAATCCCACTTCACTTCCAGTTTAAGTGTCAGCTGAGGCCTCGCCTGATCATTTGATTCAGAGTAGCCCTAGTTCTCACAAcactatctgaattttctacatatcacatcacagactaatattgtttataccagtcttgtttcctcctaataaaatataagtgccatgaaagaa

Publications

PMID - Link Title