Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name CHAF1BP1
Plot displaying the genomic locations of a retrocopy (in chr6) and its respective parental gene (in chr21). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr6:105666280-105668460  UCSC
Coordinates (T2T) chr6:106842058-106844238  UCSC
Coordinates (hg19) chr6:106114155-106116335  UCSC
Strand +
Parental Sequence NM_005441.3
Parental seq. overlap 1979 bp
Parental seq. overlap (%) 44.2%
Genomic Region Intergenic
Retrocopy Summary CHAF1BP1, located on chr6:105666280-105668460, is a retrocopy of the parental gene CHAF1B. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name CHAF1B
Full Name chromatin assembly factor 1 subunit B
Also known as CAF-1|CAF-IP60|CAF1|CAF1A|CAF1P60|MPHOSPH7|MPP7
Coordinate chr21:36380145-36419015
Strand +
Gene summary Chromatin assembly factor I (CAF-I) is required for the assembly of histone octamers onto newly-replicated DNA. CAF-I is composed of three protein subunits, p50, p60, and p150. The protein encoded by this gene corresponds to the p60 subunit and is required for chromatin assembly after replication. The encoded protein is differentially phosphorylated in a cell cycle-dependent manner. In addition, it is normally found in the nucleus except during mitosis, when it is released into the cytoplasm. This protein is a member of the WD-repeat HIR1 family and may also be involved in DNA repair. [provided by RefSeq, Jul 2008]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes CHAF1BP1
Bonobo Pan paniscus CHAF1BP1
Gorilla Gorilla gorilla CHAF1BP1
Orangutan Pongo abelii CHAF1BP1
Gibbon Nomascus leucogenys CHAF1BP1
Green monkey Chlorocebus sabaeus CHAF1BP1
Crab-eating macaque Macaca fascicularis CHAF1BP1
Rhesus Macaca mulatta CHAF1BP1
Baboon Papio anubis CHAF1BP1
Golden snub-nosed monkey Rhinopithecus roxellana CHAF1BP1
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>CHAF1BP1
CAGAACGGTGCCGGAGAAACGTTTTGCACCTTCAAGACTCAGGAGGATGAAAGTTATCACTTGTGAAGTAGCCTGGCATGACAAAGAGCCTGTGTACAGCCTGGACTTCCAGCATGGGATGGCCGGGAGGACGCACAGACTGATGTCTGCAGGCATGGACTCCGTTGTCAGGATCTGGAACGTAGAAAAGGGACTAGATGGAAACGACATCATGGAATTTTTGTTCAATCTTGCTTGTCATACCAAAGCCTTCAATGTCCTGCATTTTTCTCCATCTGGGGAGATTTTAGCATCGGGAGGAGATGATGCTGTCATCCTGTTGTAGAAGGTGAATGATAACAAAGAGCTGGAGCAGATTTCTTTTCAGGATGAGGACGAGGCCCAGTTGAACAAGGAGAACTGGATGGTTGTGAAGACTCTGCGGGGCCACTTAGAAGATGTGTATGATATTTGGTGGGCAACTGATGGGAATTTTATGGCTTCTCCCTCTGTGGATGACACAGCCATCATATGGGATGTCAATAAAGGACAAAAAATATCAATTAACATAACAGAAAAGTTATGTCCAAGGAATAAACTGGGACCCTTTAGGTCAATATGTTGCTACTCTGAGCTGTGACACGGTGCTGCAGGTATACAATATACAGAAGAAGCATGTGGTTTTTAATGTTTCAAAGATGCTATCTGGAATAGGGGCTGAAGGAGAGGCAAGAAGCTACCGCATGTTTCATGATGACAGCATGAAGTTGTTCTTCCATAGACTGAGTTTCACTCCCAATGGATCTTTGCTCCTCACACCAGCCAGATGTGTGGAATCCGGTGAAAATGTAATGAACATCACTTACGTTTTCTCCGGGAAGGATCTTAAAAGGCCCATCGCTCATCTTCCGTGTCCTGGAAAAGCCACTCTTGCTGTTGGCAGCTGTCTGGTCTATTTTGAACTGAGGCCAGTGGTGGAAACAGGTGCGGAGCTAATGAGTCTGCCCTACCGCCTGGTATTTGCTGTGGCTTAGGAGGACTCTGTGCTTCTGGACACCCAGGAGTCCTTCCCTTTCGGTTATGTGTCTAATATACATTACCACACCCTCAATGACATTTCATGGTCTAGCGATGGCGCCTTCCTGGCCATTTCTTCCACAGACAGTTACTGCTCGTTTGTGACATTTGAGAAACGTGAACTTGGAATTCTTTTAAAAGAGAAGTCAGTTTTGAGCATGAGAACTCCTGATACAGCAAAGAAAACCAAGAGTCAGACACACCAAGGGTCTTTGCCAGGACCCAGACCCGTAGAGGGAACAACTGCCAGCAGAACCCAAGACCCCAGCAACCCCTGCTCAACCCCCACTCAGGCCAGACAGGCCCCAGCCCCAACAGCCACCAGGGACCCTCCCTCTATCATTCTGCTGTCAAAAGCTCCTTGCCGAGGCCTTCGGAGGAGAAGACCCTGCCGCCCAGTAGTTAAAACACAAAAGCCCACCCATCCCGGAGGGTCACTCTGAACACACTGCAATCCTGGAGCAAGACAACACCCTGGAGAATAAACTCAATACCCTTAAAGACAGACACTCCACCAAAGTCTGTACCAATCAATGTAATCTCCACCCCTTCTGCAGAAGAATTTAGTAAGAGACGCCTGGAAATGCTCAGGACAGTCCCGTAGAGCTAAAACAGCCCAGACTCAGTGAAAACAAAGGGGGCACTGAAAGTCTGGAACCTTGATGGGACCTTGGCTTCTGCTCAAAGCCTTCCAGACCTCCCATGTGTGCAATGAGGTGGTGAAGCTGGAGATGCCTGAGACCAGTTGCTTCCATGGAGCGGGACAGATGCCGTAAATGGATTTCTGTAACAGAAGTGACATGTGTACTGATTTTTCTCCAGAAATATGGATGCTGTTTTATTCAGTCTCCATTTTTAACTTGGGGATGTGAACATTTTAACATACTGAATCCTCTTTTTCATGAGTCTCTGAAACTGGAGCAGTTCAACATTATCCAGTGTGAAAATCAATGAGTCCTCCCTGGCATCCTCGTGAAAGTGCAGACACTTCATGGAGGGACTCCTTTTAAAGTTAGAATTAGGAAGATGAGAAAGTAATTTGAGATTTTACTCGGTTGAATTTTAGAGTATTTGAAGTAATTGTTAGATATTTGCTTCTCAGGAGTTGATTAAACTTTGGAAGGT
>NM_005441.3
gggaagcggcgcgcgctgcgcggGAGGTGACGGTGCCTCTGACTGTCCGGGTCCCTCCAGCATTTTGCAGCTTTCTCCTGTCTTGAAGAAGTAGAACGGTGCCCGAGAAACGTTTTTCCCCTTCGAGACTCAGGAGGATGAAAGTCATCACTTGTGAAATAGCCTGGCACAACAAGGAGCCCGTGTACAGCCTGGACTTCCAGCATGGGACGGCTGGGAGGATCCACAGACTGGCGTCTGCCGGCGTGGACACCAATGTCAGGATCTGGAAGGTAGAAAAGGGACCAGATGGAAAAGCCATCGTGGAATTTTTGTCCAATCTTGCTCGTCATACCAAAGCCGTCAATGTTGTGCGTTTTTCTCCAACTGGGGAAATTTTAGCATCGGGAGGAGATGATGCTGTCATCCTATTGTGGAAGGTGAATGATAACAAGGAGCCGGAGCAGATCGCTTTTCAGGATGAGGACGAGGCCCAGCTGAACAAGGAGAACTGGACGGTTGTGAAGACTCTGCGGGGCCACTTAGAAGATGTGTATGATATTTGCTGGGCAACTGATGGGAATTTAATGGCTTCTGCCTCTGTGGATAACACAGCCATCATATGGGATGTCAGCAAAGGACAAAAGATATCAATTTTTAATGAACATAAAAGTTATGTCCAAGGAGTAACCTGGGACCCTTTGGGTCAATATGTTGCTACTCTGAGCTGTGACAGGGTGCTGCGAGTATACAGTATACAGAAGAAGCGTGTGGCTTTCAATGTTTCGAAGATGCTGTCTGGAATAGGGGCTGAAGGAGAGGCAAGAAGCTACCGGATGTTTCACGACGACAGCATGAAGTCTTTCTTCCGTAGACTGAGTTTCACTCCCGACGGATCTTTGCTTCTCACGCCAGCTGGATGTGTGGAATCTGGTGAAAATGTAATGAATACCACTTATGTTTTCTCCAGGAAGAATCTTAAAAGGCCCATCGCTCATCTTCCATGTCCTGGAAAAGCCACTCTTGCTGTTCGCTGCTGTCCGGTCTACTTTGAACTGAGGCCAGTGGTGGAAACAGGTGTGGAGCTGATGAGTCTGCCCTACCGCCTGGTGTTTGCTGTGGCCTCGGAGGATTCCGTGCTTCTGTATGACACCCAGCAGTCCTTCCCTTTTGGTTACGTGTCTAATATACATTACCACACCCTCAGTGACATTTCATGGTCCAGCGATGGTGCCTTCCTGGCCATTTCTTCCACGGACGGTTACTGCTCATTTGTGACATTTGAGAAAGATGAACTTGGAATTCCTTTGAAAGAGAAGCCAGTTTTGAACATGAGAACTCCTGATACAGCAAAGAAAACCAAGAGTCAGACACATCGAGGGTCTTCGCCAGGACCCAGACCGGTAGAGGGAACCCCTGCCAGCAGAACCCAAGACCCCAGCAGCCCCGGCACGACTCCCCCTCAGGCCAGACAGGCCCCAGCCCCAACAGTCATCAGGGACCCTCCCTCCATCACTCCTGCTGTCAAAAGCCCCTTGCCGGGGCCTTCGGAGGAGAAGACCCTGCAGCCCAGTAGTCAAAACACAAAAGCCCACCCATCCCGGAGGGTCACTCTGAACACACTGCAAGCCTGGAGCAAGACAACACCCCGGAGAATAAACTTAACACCCTTAAAGACGGACACTCCACCAAGTTCTGTACCAACCAGTGTGATTTCCACCCCTTCTACAGAAGAAATTCAGTCAGAGACGCCTGGAGACGCTCAGGGCAGTCCCCCAGAGCTAAAGCGGCCCAGACTCGATGAAAACAAAGGAGGCACGGAAAGTCTGGACCCTTGATGGGACCTCGGCTTCTGCTCGAAGCCTACCAGGCTCCCGGTGTGTGCAGGGAGACGGTAAAGCTGGAGGTGCCTGAGACCAGGGCTTCCATGGAGCGGGACACACTGTAAATGGATTTCTATAACAGAAGTGACATGTGTACTGATTTTTCTCCAGAAATATGGATGCTGTTGTATTCAGTATCCATTTTTAACTTGGGACATGAACGTTTTAACGTAGTAAATCCTCTTTTTGATGAGTTTCTGAAACTGGAGCGGTTCAACGTTATCCAGTGTGAAAATCAGTGAGTCCTCCCTGGCATCCTCGTGAAAGTGCACACACTTCATGGAGGGACTCCTTTTCAATAAGAATTAGGAAGATGAGAAAGTAATTTGAGATTTTACTCTGTCGAATTTTAGAGTATTTGAAGTGATTGTTAGATTTCACTTCTAAGGAGTTGATTGATTAAACTTTGGAAGGTAGTTGTGTTTGTTTTCTGATTTTAAAGGTGACGATGCTTATTCTTTTAGTAACTAAGTGAAGTGAAAAAGATGGGTATCACCCATCATCTTCCCACCAGAAGTAACCCTCGTTAATGTTGTAGTATATTTCCTTAGCATTTTTGTGGATCTATTTATTCTAAAAAGAGAATTGAGATTTTATTTCATATGCAATTTGGTATCTAAATAGGTTAGTTTTTTAGATTGGTTTTTCAAAGCAAAAAAAGTATCttttttgttttttgagacagggtcttgctctgttgcccaggctggagtgcagtggcgctatctcagctcactgcagcctcgacctcctgggctcgagcgatccttccacctcagcttcccgagtagctgggactacaggcatgtgccaccatgccatgctaatttcacacacacatgcacccacacacacacatatatatgatacatatatatatatatacacacacacacaagtatgtgtgtatatatatattttttttcttttttttttgagatggagtctcactctgtcgcccaggctggagtacagtggcacaatctcggctcactataacctccgcctcctgggttcaaacgattctcctgcctctgcctcttgagtagctaggattacaggtgtgtgccaccacatccggctaatttttatatttttagtagagatggggttttgccatgttggccaagctggtctctaactcctgacctcagatgatctgcctgcctcggcctcccaaagtgttgggattacaggtgtgagctactgcacctggcctaattattatatttttaggggagacggggtttttccatgttgcccaggctggtctcgaactcctggggctcaagtaatcctccctccccagcctcccaaagtgttgggattacaggcgtgagacaccatgcctggtcAAATGGTATCTGTTTTGACGGgtggttctcaactgtagctgcatactgaaatcacctaagagctgacataccagtgcctgggttcccgcttcggaggatttggcctaatcggtctggggtatgttctgaatattaggatttcttaaagctcctggagtaattctgatgcgcagccaagattgagaaATCTAAGGGAAAAAACTTTCCCTGGATACGGTCTGTTCTGGTTAAATGCATTTCCACTGAAAGCAtttttttttttttccgagacagagtctcgctctgtcacccaggctggagtgcagtggcgcaatctccactcactgcaacctcacctcctaggttcaagggattctcctgcctcagcctctccagtagctgggattacaggcacccgccaccacgcccggctaatttttgtatttttagtagagatggtgtttcaccatgttggtcaggctggtctccaacgcctgacctcgtgatctgcccacctcagcctcccaaagtgctgggattacaggcgtgagccaccgcgcccagccGAAAGCATTTTCTTGATTATCTCTGCCCCGTCACTGATTGACATCCTCCTTTGCTGGGGCCGCGGACTGAAGGACAGTATGCAGGAGGTGCCATCAGCTCTTCTGAAAAGAGACAGCTTTCAGTGTCATGTGGCTGGCGTGAGGTGCGGTTTGCAGTTGTTGATCCTGTGCAGACAGATGAATGACCATGGGTCCCCTGTCCTTATTGAGCAGCCTGCTTCCTGGCCATACCTGGGGAGGAACAGTATTAGGTTTTTctgggtgtggtggctcacacctgtaatcccagcactttgggaggccaaggtgggtggatcacttgaggttgggagtttgagaccagcctggccaacatggtggaaccccatctctactaaaaatacaaaaactagccaggcgcggtggcacacacttgtaatcccagctactcgggaggctgaggcacaagaatcgcttgaacccgggaggcggagtttgtagtgagctgagatggtgccactgtactccagcctgggcgacagagcgagactctgtctcaaaaaaaaaaaaaaagagaaaaagaagaaCAGTATTAGGTTTTACAAATCTGTTTCTTGTGCATTGATTGTGGGAGTTGGGGTGGGGGACCCCTGATGGCCTGCCTGTTCTCAGCCATCATCCTTAAATATAAATCAAAATTGGCAATAAAAGACCAAGTGAAGTCA

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