Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name ZPR1P1
Plot displaying the genomic locations of a retrocopy (in chr6) and its respective parental gene (in chr11). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr6:108785326-108787053  UCSC
Coordinates (T2T) chr6:109962681-109964408  UCSC
Coordinates (hg19) chr6:109106529-109108256  UCSC
Strand -
Parental Sequence NM_003904.5
Parental seq. overlap 1616 bp
Parental seq. overlap (%) 24.7%
Genomic Region Intergenic
Retrocopy Summary ZPR1P1, located on chr6:108785326-108787053, is a retrocopy of the parental gene ZPR1. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name ZPR1
Full Name ZPR1 zinc finger
Also known as GKAF|ZNF259
Coordinate chr11:116773799-116788023
Strand -
Gene summary The protein encoded by this gene is found in the cytoplasm of quiescent cells but translocates to the nucleolus in proliferating cells. The encoded protein interacts with survival motor neuron protein (SMN1) to enhance pre-mRNA splicing and to induce neuronal differentiation and axonal growth. Defects in this gene or the SMN1 gene can cause spinal muscular atrophy. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2015]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes ZPR1P1
Bonobo Pan paniscus ZPR1P1
Gorilla Gorilla gorilla ZPR1P1
Orangutan Pongo abelii ZPR1P1
Gibbon Nomascus leucogenys ZPR1P1
Green monkey Chlorocebus sabaeus ZPR1P1
Crab-eating macaque Macaca fascicularis ZPR1P1
Rhesus Macaca mulatta ZPR1P1
Baboon Papio anubis ZPR1P1
Golden snub-nosed monkey Rhinopithecus roxellana ZPR1P1
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>ZPR1P1
ATGGCGGCCACCGGGGCTGTGGAAGTGGGGTCCCCGGGGTCAGCCGTTGCCCCCTCGCCCGCCCTGGACTTGCTGCCTGCCCTGGGTCATCTGTTCTGGCCCATCAGCGCCGAGGACAAGGAGCAGCAGCCCACCCAGATCAAGTCACTGTGCATGAACTGTTACCGCAATGGCATGACGCGCCTCCTGCTCACCAAGATTCCCTTCTTCAGAGAAATAATCGTGAGCTCCTTTTCCTGCCACCACTGTGGCTGGAACAACACGGAGATCCAATCGGCAGGCAGGATCCAGGACCAGGGAGTGCGCTACACTTTGAGCATCAGGGCTCTGGAGGACATGAACAGAGAAGTGGTGAAGACTGACTCTGCTACCACAAGGATTCCTGAGCTAGATTTTCAAATTCCTGCCTTTAGCCAGAAAGGAGGTCTGAACACTGTTGAAGGATTGATCACCCGTGCTATCTCTGGCCGGGAGCAGGACTAGCCTGCGCGAAGGGCAACAAAGATGCCACAGCTGAAAGAATTGATGAGTTCATTGTCAAACTGAAGGAGCTAAAGCAATCAGCCTCCCCTTTCACTCTGATCATTGATGATCCCTCAGGGAACAGCTTTGTGGAAAACCCACAGGCTGCTCAGAAAGATGATGCCCTGGTGATCACACACTACAACCAGACCCGACAGCAGGAAGAGATGCTGGGGCTCCAAGCAGAAGCACCAACAGAGAAGCCAGAAGAGGAAGATCTCAGAAATGAAGTGCTCCAGTTTAACACAAACGGCCCAGAATGCAATGCCCCCACTCAGACCAACATGAAGCTAGTACAAATCCCTCACTTTAAGGAGGGACCAAGTACAAGAACTGCGTGCATCAGACCAATGAGGTGAAATCTGGAGAAGCAGTAGAACCCTTGGGCACCAGGATCACCCTCCACATCACAGGTCCCTCAGATATGACCAGAGACCTCCTCAAGTCTGAGACTTGTAGTGTGGAAATCCCAGAGCCAGAATTTGACTGGGAATGGCCATCCTCAGGTGCAAGTTCACCACACTAGAAGGGCTGCTGAAAGATATCTGGGAACTGGTGACCAAAAACCCTTTCACACTGGGCGACAGTTCCAATCCTGGCCAGACGGAGAGACTGCAGGAGTTTAGCCAGAAGATGGACCAGATCATCGAAGGTAACATGAAGACCGACTTTATTATGGATGATTCAGCAGGAAACAGTTACTTGCAGAATGTGTATGCAACTGAAGATGATCCTGAGATGAAGGCGGAGCATTATAAGCACACCTTTGACTAAAATGAGGAGCTAGAGCTCAATGACATGAAGACAGAGGGCTATGAGGCAGGCCTGGCTCCACAACGGTAGCAGTGGGTGGGTCAAGGGCCAGCTCTCCAGCGCTGCTCATTCTGCAGGTTATTTATTAGTATTGGAAGAAGGCTGGGAGTGTCTTGCCCACCAGCCCTTGCCCATGGTGGGGAGGACATCTTGTCTGAGTCAGAGATCTAGGCACATTTTCTAAACAGCTTGTAATGCAAGTGTGAGCCTATTGTGTTACTTGACCTTATTTTGAGGCTTTGAATTGGCCTAGGAAGAAACCCAGAAATGAACCAGGGGTATGTCATTATCACTTTTTTCATATCAAGTCTTTACCCTCCCTCCACATAATGCTCTGTCCTCTAAGGTTGGAACTCTGAAGTTGGAGAAAGTGGAATAAAATTACACCTGGAA
>NM_003904.5
AGGAAGCCGAGGTCTGAATTGCGCGTGGTGGCCATGGCGGCCAGCGGGGCTGTGGAACCAGGGCCCCCGGGGGCTGCCGTCGCCCCGTCGCCCGCCCCGGCCCCGCCGCCTGCCCCTGATCACCTGTTCCGGCCCATCAGCGCCGAGGACGAGGAGCAGCAGCCCACCGAGATCGAGTCGCTATGCATGAACTGTTACTGCAATGGCATGACGCGCCTCCTGCTCACCAAGATTCCCTTCTTCAGAGAAATAATAGTGAGCTCCTTTTCCTGCGAGCACTGTGGCTGGAACAACACGGAGATCCAGTCGGCAGGCAGGATCCAGGACCAGGGAGTGCGCTACACTTTGTCTGTCAGGGCTCTGGAGGACATGAACAGAGAAGTGGTGAAGACTGACTCTGCTGCCACAAGGATTCCTGAGCTAGATTTTGAAATTCCTGCCTTTAGCCAGAAAGGAGctctgaccactGTTGAAGGATTGATCACCCGTGCTATCTCTGGCCTGGAGCAGGACCAGCCTGCACGAAGGGCAAACAAAGATGCTACAGCTGAAAGAATTGATGAGTTCATTGTCAAACTGAAGGAGCTAAAGCAAGTAGCCTCCCCTTTCACTCTGATCATTGATGATCCCTCAGGGAACAGTTTTGTGGAAAACCCACATGCTCCTCAGAAAGATGATGCCCTGGTGATCACACACTACAACCGGACCCGACAGCAGGAAGAGATGCTGGGGCTTCAAGAAGAAGCACCAGCAGAGAAGCCAGAAGAGGAAGATCTCAGAAATGAAGTGCTCCAGTTCAGCACAAACTGCCCAGAATGCAATGCCCCCGCTCAGACCAACATGAAGCTAGTACAAATCCCTCACTTTAAGGAGGTTATCATCATGGCTACCAACTGCGAGAACTGTGGGCATCGGACCAATGAGGTGAAATCTGGAGGAGCAGTAGAACCCTTGGGCACCAGGATCACCCTCCACATCACAGATGCCTCAGATATGACCAGAGACCTCCTCAAGTCTGAGACTTGCAGTGTGGAAATCCCAGAGCTAGAATTTGAACTGGGAATGGCAGTCCTCGGGGGCAAGTTCACCACACTGGAAGGGCTGCTGAAAGACATCCGGGAACTGGTGACCAAAAATCCTTTCACACTGGGCGACAGTTCCAATCCTGGACAGACGGAGAGACTACAGGAGTTTAGCCAGAAGATGGACCAGATCATCGAAGGTAACATGAAGGCCCACTTTATTATGGATGATCCAGCAGGAAACAGTTACTTGCAGAATGTGTATGCGCCTGAAGATGATCCTGAGATGAAGGTGGAGCGTTACAAGCGCACCTTTGACCAAAATGAGGAGCTAGGGCTCAATGACATGAAGACAGAGGGCTATGAGGCAGGCCTGGCTCCGCAACGGTAGCAGTGGGTGGCTCAAGGGCCAGCCTCCAGCGCTGCTCTTTCTGTAGGTTATTTATTAGTATTGGATGAAGGCGAAGGCTGGGAGTGTCTTTCCCACCAGCCCTTGCCCATGGTGGGGAGGACATCTGGTCTGAGTCAGAGATCTGTGCACACTTTCTAAACAGCTTGTGATGCAAGTGTGAGCCTATTGTGTTACTTGACCTTATTTTGGAAGTTTTGAATTGGCCTAGGAGGAAACCCAGAAATGAACCAGGGGTATGTCATCACTTTTTTCATATCAAGTCCTCACCCTCCTTCCACATAATGCTCTATCCTCTAAGGTTGGAACTCTGAAGTTGGAGAAGGTGGAATAAAGTTACACCTGGAGTTTGTTGTTGGTTTTGAGTATATAAAATACTGACTTTGAACAGGAAAGGAGTCTCCTGAGGGGAGACCGAGTCCAGCACAAGTGAAGGAGTTACCATTGAAATGATGACTTTCAAACAGCACTGGCCTCTGTATTGACCCTATCCTTGTTTGATATCATGCTGTTAGAATTCAGCCTCCTAAAGAAAATTTTCCCGTGTATCTACTGTAATTTGGGGATTGCAGCTGGCATTTAattcattccttcagcagatgcttgcttatctactttatgccaagcacaccacagaacagaggacaaaataaatctctttcatggaacttgaagtctagtggggaaaaatgacaataaacagatcaggaaaacagtacatcagatggtgattagtgtcatggaggaatgtaaagcagggaatggggctgggttgtgcaaggaaatggggagtagggaagatcttctgaacaagaaggtgataatttgacatttgggcaaagctgaggaggaggtcagggagtgagctgtgtgggtatctgggggaagagatttcctggcagagggaactgcaaatgctagagctgtgaggttagagcCAGTGGGGGTACCTGATCAGTTAGCCCTACTCTCAGTTAGAAATGTTGAAACACATTCATCCAGAGAGAAAGGAGGCTCTCTGCAGTTCTTCTGAAAGTTAAGGACCAGTGAACACTCTGCTGCTTGGGCCCTGGACTTCCCAGCCAGTGTTCTTTGCACTGTAGTCTCCTGCCTCTCATAAACAAAAGGTGACTCCTGTGGTGCAGACTGCAGGGTATTTGTTCAATAAAGACCAGTTCATTGATTAAGATGTTATCACAAACCTTATTGCTTTGTGTTGCAAACtttttttttttttttttttggtagagacagagtctcgcgctgttgcccaggctggagtgcagtggtgtgatcttggcttattgcaacctttgcctcccgggtttaagcaattctgcctcagcctcccgagtagcggggactacaggcgcacgccgccacacccagctaatttcttttgtattttagtagagacggggtttcaccgtgttgcccaggctggtctcgaactcctgagctcaggcaatccgccagccttggcctcccaaagtgctaggattacaggcgtgagctaccgcgtccggcTGTGTTGCAAACTTAACTCTGAAGAATGAGTTAGAGATGATTTAGCAATCAGACATCTACTCTCGTTGCTCTGTTAAACTACTCTCAAAGGTCACAAGTGATTTTCCACTTGGAAAGTGTTATCTATTTCTGTCACATTTGATAGTGGACCATCTCTTCTTAACCCTTCTTTTGGCTCTCGAGATACTGTACCCTTGGTTTTCCCTTCACTTTGAATATTTCTTATTTGGACACTTTGCCTCCTCCCCTCTTACTAAATTTGTTTCTGAGAGTTCTGCTTTCAGACATCTCTCCATATCAGATTCTTTGGCATCTTACTATCATGTGGGACTAACTTCCATACCTGTATCTCTAATTTCTGTAAGTGAGGGCGAGAGTAAGGTGTTTGGAGACTCAGGTTAGCAAATGACTCATTCAAACTATAAAGCTTCAGTACTTTGGGCAAACTTCTCACAGGCAACTATTCTACCCTAAGAGATTATCTCTAGGTATGTTTCCAGCTGACTTGGgaatctaagtttaccagacaaccctctgatctatcatttggtctcttaagtagacttccccatagtgtaggtgtgctctgttaagataaactgcagtatcaggttcattttccattgtgaaggaaaaaaaatggcactctggcttattactgaatctcttgtgagtttggttggtgtgaggcaatctcccagaatccacccagttcctaggaaatgatgacctgagtttctgaacttgaagactgaggaccaggtgccagactgggataacccagctaaggtacttcctgccctttgaTGACAAGGCATTCTTCAGTTTCATACCCTTCTCTTGAATTATCTTTCAGCTCCTTTCTCATTTCATAAAGTGTGTCAGGATGGGAGCTTACATATAGTTAACTGAGTCTTGCTCCACAGCACCCAGCATATGACACATGGTTAATAAAATCTGTTAAAATCCTCCATCATAGATTAAACCCTATTAGGACACTAGGGATAACATCTATAGGTAAAAAGATAGGGAAAGGGTCTCGCTTTAAGGCCAGGGTAGGTGAGTCAAAGTGCCAGGAACATGTGGATTCAGTTTCACAGCCATGAGTAACATTTAAGTGGAAAAGGTTTGTGATTGTGTTAAAAAAGGAAAGTGGTTCATGCATGAGGGCACGCCTCCTACTTTCATGGGTCAAGTATGTGAAATGCAGCCATGTTCGGTCATTAGACGTGTGGACGAACATACAGGTAGGTACTGAATGTACATCTGTGTCATGATGAGTGGAGGAGGGGAGGTGAGTGTTGGGAGCAAGTATGAAGGGCAGTTGACTTGGCCAACTGAAAACTTTAATGATGGCAACACTTTCATTCTAACATCAGTATATTTCCTTCTTTGTACACCTGTGGTATGTGCCTGATGCACACTGCAGAAAATGGTGTCTCTGCTTACATTTAGGGCAGTGGTGGCTAAGACTACTTGGCTTTATTCCTATTAAAAAATGTTTTTTACACACTTCTTTTTAAGGCAAATGGCAGTGTTTCCAACTGTGGAGAGAAAAAGCTGCTTATTTTGTGCGTTCACCTCAGTTTAGTATTGGcacttccaatgcttgttttcctagtctgtaaaatggggataattaggataaacaaaattatccccattttacaggtgacaaaacagcctcagagaggttaCTTCCAGAAGGAAGCAGAGCtttttttttttttttttttttttttttttttttttgagacggagtctcactctgttgcccagactggagtgcagtggcgtgatcttggctcaccacaacctctgcctcccaggttcaagcgattctcttgcctcagccttctgagtagctgggactacaggtgcacgccaccatgcctggctaattttttttttttttttttttttggagacagtcttgctctgtcacccaggatggagtgcagtggtgcgatcttggctcactgcagccttgcctcctgggttcaagcaattctcctgcctcagcctcctgagtagctgggattacagacgcccaccactgcacccagctaatttttgtatttttagtagagatggggtttcaccatgttggtcaggctggtctcaaacccctgacctcgtgatccacctgccttggcctcccaaagtgcagggattacaggcgtgagccaccgtgcctggccAGAAGTAGAGCTTCTAAGAGGCAGGTGTCAAACCCATGCCAGTCAGACTCTGAAACCTGAGGTCTGAATATTTTAAGCTCAGCTCCACAATTACTGTATTTGTTCTATTAGATACAACTGCAGAGAGAGGCCAAAGCTCAGAGCAGGCCATTGGCACGGCATCTGATCCTGCTTAACTGCCCTGCAGCACAGGGTGGAGACACTTGGGCCTTGTCAGGCTAAGGGACTGGGGTAGGATGGGTAGCAGTGGAATTGAAGACAAAGAAAACAAATGGGCAGAAGATGGGTGGGTGGAAGTTCAGAGGGCTATCCTGGCAGTGTTCACTGGAGCAGAAGTGTGAGGCTTTCTGAATGCCTGCTGACACCAGGGTGGGGCAGGGCTGTGTAGTGTGAGATGCACCAAATTGGACGAGAAGCCAAGGCAGGCTTGTGTATGGGGTACCCTGGGGCCCTCCGCCTAGTGAAGCCCTATCTTCTCAGCCCAGCGTCCTCGTCTCACAAGCCCTCAGAGCCCCAGCCTGCTTTCCTTTCTGGGCCTGTGCTGCAACCCCCTCAACATGGCCCACTGGGTAAAAATTCATGCTTCAAGACtgatccccaagcctgttttgtattatatgagtaaagaattttttaaacacttatccccagataatgtgtatttatttataaagtatagccctgtctgcttgactaatatattaAAAAAGTGACCTTTTTGACTCTTGGTCCAAGAAACTATTGTTTGCACTTTTGTGTAGTTGTGTATAGCATCCTGCAAATTCTGTCAGAAGTCTGTGATTTCAGTAACACTAAAACTTCTCTCtcaaatggtacaagttttcagttttaagacaagttctgggaatctaatgtacaacatgttgactatagctaataattctgtattgtttacttgaagtttgctaagacaaatttgcttaagtgcccccccaccgaactactacataaattagtgaaggatgttttacttaatttgattttggtaatcattacacaatgtataattatatccagtcatcacattgtacaccttgaatatatataattttttgtcaaataataaagctgggaagaAAACGATAAAACTGACAATCTAACATATATGATGAGGTAAAAAGATCTGGTATTTCAAGAAATTTGGATGACCTCTTGCACCCCACTTCGctagcctctactccctagagtcatgttctgactatgtgaagttgagcaacttccttaatcttgccacgcttcagttcttatctgtaaaatatgataatgaaacgatttgagaattgtgagggttaaatgagataattcaggtaaagctctaaacCCCCTGCAAAGAATAAAGTCTTTTCTTTCCCCCCAAAA

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