Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name ETF1P2
Plot displaying the genomic locations of a retrocopy (in chr7) and its respective parental gene (in chr5). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr7:151502248-151504316  UCSC
Coordinates (T2T) chr7:152675075-152677145  UCSC
Coordinates (hg19) chr7:151199334-151201402  UCSC
Strand +
Parental Sequence XM_017009221.2
Parental seq. overlap 1820 bp
Parental seq. overlap (%) 49.7%
Genomic Region Intragenic (RHEB)
Retrocopy Summary ETF1P2, located on chr7:151502248-151504316, is a retrocopy of the parental gene ETF1. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name ETF1
Full Name eukaryotic translation termination factor 1
Also known as D5S1995|ERF|ERF1|RF1|SUP45L1|TB3-1
Coordinate chr5:138506095-138543236
Strand -
Gene summary This gene encodes a class-1 polypeptide chain release factor. The encoded protein plays an essential role in directing termination of mRNA translation from the termination codons UAA, UAG and UGA. This protein is a component of the SURF complex which promotes degradation of prematurely terminated mRNAs via the mechanism of nonsense-mediated mRNA decay (NMD). Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 6, 7, and X. [provided by RefSeq, Aug 2013]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes ETF1P2
Bonobo Pan paniscus ETF1P2
Gorilla Gorilla gorilla ETF1P2
Orangutan Pongo abelii ETF1P2
Gibbon Nomascus leucogenys ETF1P1
Green monkey Chlorocebus sabaeus ETF1P3
Crab-eating macaque Macaca fascicularis ETF1P1
Rhesus Macaca mulatta ETF1P1
Baboon Papio anubis ETF1P1
Golden snub-nosed monkey Rhinopithecus roxellana ETF1P2
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>ETF1P2
GGAGCTTGGAGGCAGCCTGCAGCAATGGCACTAGCATGATATCACTGATCATTCCTCCCAAAGACCAGATTTCACCAGTGGCAAAAATGTTATCAGATGAGTTTGGAACTGCATCTAACATTAAGGCAGGAGTAAACCGCCATCCAGTCCTGGGAGCCATTACATCTATACAACAAAGGCTCAAACTTTATAACAAAGTACCTCCAGATGGTCTGGTTGTTTACTGTGGAACAACTGTAACAGAAGAAGGAAAGGAAAAGAAAGTCAACGTTGACTTTGAATCTTTCAAACCAATTAATACGTCATTGTATTGTGTGACAACAAATTCCATAAAGGGGCTCTTACAGCACTACTTTCAGATGACAGCAAGTTTGGATTCATTGTAATAGATGGTAGTGGTGCACTTTTTGGCACACTCCAAGGAAACACAAGAGAAGTCCTGCACAAATTCACTGTGGATCTCCCAAAGAAACACAGTAGAGGCGTTTTGCCCGTTTAAAAATGGAAAAGCGACATAACTATGTTCAGAAAGTAGCAGAGACTGCTGTGCAGCTATTTCTGGGGACAAAGTGAATGTGGCTGGTCTAGTTTTAGCTGGATCTGCTGACTTTGAACTAAGTCAATCTGATATGTTTGATCAGAGGTTACAATCGAAAGTTTTAAAATTAGTTGATATATCCTATGGTGGTGAAAATGGATTCAATCAAGCTACTGAGTTATCTACTGAAGTCCTCTCCGAAGTGAAATTCATTCAAGAAAAGAAATCAATAGAACGATACTTTGATGAAATCACCCAGGACACGCGAAAGTACTGTTTTGGCGTTGAAGATACACTAAAGACTTTGGAAAAGGGAGCTGTAGAAATTCTAATGGTCTATGAAAATCTGGATATAATGAGATATGTTCTTTATTGCCAAGGCACAGAAAAGGAGAAAATTCTCTAACTCCAAAGCAAGAAAAGGATAAATCTCATTTCACAGACAAAGAGACCGGACAGGAACATGAGCTTATCGAGAGCATGCCCCTGTTGGAATGGTTTGCTAACAACTATAAAAAATTTGGAGCTATGTTGGAAATGATCACAGATAAAATGCAAGACGGGTCTCGGTTTGTGAAAGGATTTGGTGGAATTGGAGGTATCCTGCAGTACCGAGTAGATTTCCAGGGAATGGAATACCAAGGAGGAGACAATGAATTTTTTGACCTTGATGACTAGACATGAGTCTGGCAAAACGTGCCTCACCCTCCAGCATCCAACCCAAGAAGCATACCCATGGTGGAATTCTAACAGATCCCTGCCTTACAACTGAAACACTTCCAGAACTTTATCCATGAGTACTGGTTATTGAAAAGATAACTGAAACAAAACCAGACCCAACCCCACACTTTGTTTTGTCATGGTGTCAGCGCAGCAGCCTACAACTAAGTTCCTAAATGCCACTTTGGACTAATTTAAACAAGAATCCCAGTTTTTACTTTTACTCGATGGTGAAATTCGTTGCTCTTGTATTTTATGAAAAAAAAAAAAATTTTTTTAAGCCTTCATATACAGAAGTAAAAATATTTTAACTGCTGTAAACCTTCAAAAGTTAATAGAAGTGAGATCATACTGGTTTTTTTCTTATTTTGATTGGAGAAAAATTAAATTGCTGCATTTCGCAGTGATCCATTTACATGGCATTCCCAGCTTAGACTGCATAAGAAATAGATGTGGTGAAATGTTGGAACCATTTCTCTCTTGGTCTGTTTAATGTTGAAAGGGTGAGCTAATAGGAGGCAATTTCAACTTCACTCCCTCAAGCTACCCTGTCTCCCTCCAGACTGGCAGTTTCAAGGATGCAAACTGCATTGCAAAATCAAACTGACTCATGAAGCATTTGGGCCAGTGCACTGTTTACTTCCATCTGTTTGCTGACACATTTGTGCCCAGCGTTTGGGAGCCCTTTGTATCAACGTTCTGACAAGTGTCCCTATAACCTTAACCTACTCGAAACCAGTTTGGGTTGGATATGATGGGGCTTCTGTGCTATTGCTGGGATTGGGGGAAATAAAACATGCAATTTAAGTGG
>XM_017009221.2
ATTGCAACACATGCAGCTGCCTGGAGAGAGGGAGCCGGTGTCCTACGTCAGAgccgccgccgccgcggagccgccgccggggaggagcagccgctgccgccCAGGACTGGGCCCTTAGGGAGGAGGAGGCGAGAAGATGGCGGACGACCCCAGTGCTGCCGACAGGAACGTGGAGATCTGGAAGATCAAGAAGCTCATTAAGAGCTTGGAGGCGGCCCGCGGCAATGGCACCAGCATGATATCATTGATCATTCCTCCCAAAGACCAGATTTCACGAGTGGCAAAAATGTTAGCGGATGAGTTTGGAACTGCATCTAACATTAAGTCACGAGTAAACCGCCTTTCAGTCCTGGGAGCCATTACATCTGTACAACAAAGACTCAAACTTTATAACAAAGTACCTCCAAATGGTCTGGTTGTATACTGTGGAACAATTGTAACAGAAGAAGGAAAGGAAAAGAAAGTCAACATTGACTTTGAACCTTTCAAACCAATTAATACGTCATTGTATTTGTGTGACAACAAATTCCATACAGAGGCTCTTACAGCACTACTTTCAGATGATAGCAAGTTTGGATTCATTGTAATAGATGGTAGTGGTGCACTTTTTGGCACACTCCAAGGAAACACAAGAGAAGTCCTGCACAAATTCACTGTGGATCTCCCAAAGAAACACGGTAGAGGAGGTCAGTCAGCCTTGCGTTTTGCCCGTTTAAGAATGGAAAAGCGACATAACTATGTTCGGAAAGTAGCAGAGACTGCTGTGCAGCTGTTTATTTCTGGGGACAAAGTGAATGTGGCTGGTCTAGTTTTAGCTGGATCCGCTGACTTTAAAACTGAACTAAGTCAATCTGATATGTTTGATCAGAGGTTACAATCAAAAGTTTTAAAATTAGTTGATATATCCTATGGTGGTGAAAATGGATTCAACCAAGCTATTGAGTTATCTACTGAAGTCCTCTCCAACGTGAAATTCATTCAAGAGAAGAAATTAATAGAGGAGAAAATTCTCTATCTAACTCCAGAGCAAGAAAAGGATAAATCTCATTTCACAGACAAAGAGACCGGACAGGAACATGAGCTTATCGAGAGCATGCCCCTGTTGGAATGGTTTGCTAACAACTATAAAAAATTTGGAGCTACGTTGGAAATTGTCACAGATAAATCACAAGAAGGGTCTCAGTTTGTGAAAGGATTTGGTGGAATTGGAGGTATCTTGCGGTACCGAGTAGATTTCCAGGGAATGGAATACCAAGGAGGAGACGATGAATTTTTTGACCTTGATGACTACTAGGTAGTCGACATGGGTCCGGCAAAACGTGCCTCACCCTCCAGCATCCAACCCAAGGAGCATACCCATGGTGGAATCCAAACAGATCCCTGCCTTACAATTGGAACATTTCCAGAACTTAATCCATGAGCATTGGATATTGAAAAGAAAACCGAAACAAAACCAGACCCAGCCCTACACTTTGGTTTGTCATGGTGTCAGCGCAGCAGCCTACAACTAAGTTCCTAAACGCCACTTTGGACTAATTTAAAAAAGAATCCCAGTTTTTACTTTTACTGGATGGTGAAATTGGTTGCTCTTGTATTTTATGAAAAAAAATGATTTTTTTAACCTTCATACATAGAAGCAAAAATACTTTAACTGCTGTAAACCTTCAAAAGTTAATAGAAGTGAGATCATACTGGTTTGTTTCTTATTTTGATTGGAGAAAAATTAAATTGCTGCATTTCGCAGTGACCCATTTACATGGCATTCTCAGCTTAGACTGCGTAAGAAGAAATATATGTGGTGAAATGTTGGAACCATTTCTCTCTTGGTCTCTGTTTAATGTTGAAAGGGTGAGCTAATAGGAGGCACTTTCAACTTCACTCCCTCACGCTACCCCGTCCCCCTCCAGACTGGCAGTTTCAAGGATGCAAATTGCATTGCAAAATCAAACTGACTCATGAAGCATTTGGGCCAGTGCACTGTTTACTTCCATCTGTTTGCAGACACATTTGTGCCCGGCGTTTGGGAGCCCTTTGTATCAATGTTCTGACAAGGGTCCCTATAACCTTAACCTACTCGAAACCGGTTTGGGATGGATATGATGGGGCTTCTGTGCTATTGCTGGGATTGGGAGAAATAAAACATGCAATTTAAGTGGAAGCGAAGAAATTTAAAGAGGATTTTATTTTGCTTGGGTCAATCCTTGTTAAAAGGGAGGTGGATGTGTTTTCCTTGTGTTGGATGGCATGAGATTATGTGAATGTTTTGATTTATTAAAATGAACTGCAAGGTTTTTCACAGGAACGACAGACATGTATGACTGCATGTAATTATAAACTCCTGACCTCCTGGTGGGGTTGGAGCATCTGTTTCAAATGTGGGACTTACAAGCACTTCTCACATGAGAAATTAGGGGCGGGTGGGAAGGGATGGGACACAGCTTCTGGCACCATGGATTTAAGACCATGTTGGATCCAAAAGTTGGCCTGAAACCCTGAAGCTTATGCTTCACAGCTGGGCTGTAAGTCAGACTTGAACCCAGCTGATATGCAAGGTCATGGCGTGCCCAGGGTGGTGACAGTTGAACAAAGTGTATAGTACGTGCCCAGTGGTAGCGATGGAAAAAAGTATACCAAATGGACTTTGAAGGACCAAAGGTTTTAAAAGTCAATTGGTATCACCTCCACACTGACTAGGGTAGTGGGGTGCATTTGGTTTTCAAATTGGGTACTTTTAACACTTTAGTGCCTGACTGCTGTTCTTTACTGACTTGATTCAGTCACTCGTAGCTTTATTGGTCTGAACCAGCTCCTTGTTCCCAGGTTACAGACCTGCCTATCGTTCCAATAATCCTGTTTCACTTGAATGAAGGGAGTATGTCTTAAATGTAAAGTTTCTGGTTCTCACACTGTACTCTGAGGTCCAAATACTGTCTGTCAATGTGTAACCTGATGTCTCAACCCCCTGTGAGAAGAGTCCATTATTTGGTGTTCACCAACGTGGGAGACTTCACCGGAACAGGCTTTTTTGCTTTGGGCTCTGCTATTTGTTTGCAGAACACCCAAGAGCGAGCAAACATGCTCTCTTCACAGCAGTACCTTAGGGTTTTGCCATTGTAAATGGGTCTGATGTGATATGACAAGACCAGAGAAATTGGATGTAAATTTACATTTTTGAATATGCTTGTTGTTTCACATGATACATTTAGGGTATGCAGCTCCTTTTGTAGTTTTTATTTTTACTATTTAAGTTTGGAAATGATGCCAAATTTTTGTATTTCTTTAATCAATGTGTTCTCTTCGGTGatatatattgcattatatattgatgtgtgtatcaatatatattgatatgtattacacttacacatacaaacacatataAGAGGGGGTGAAAACCGTAGCCTTTGCATTCTCTATAGCCTCTGCAGAGAGATACTAAGCAGCAAAATCTTGGTGTTGTGATGTACAGAAATGGAGAAGAGTATTAAACCATATTTAAGAATA

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