Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name SMARCA5P1
Plot displaying the genomic locations of a retrocopy (in chr7) and its respective parental gene (in chr4). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr7:77071837-77072336  UCSC
Coordinates (T2T) chr7:78322940-78323439  UCSC
Coordinates (hg19) chr7:76701154-76701653  UCSC
Strand -
Parental Sequence NM_003601.4
Parental seq. overlap 418 bp
Parental seq. overlap (%) 5.4%
Genomic Region Intergenic
Retrocopy Summary SMARCA5P1, located on chr7:77071837-77072336, is a retrocopy of the parental gene SMARCA5. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name SMARCA5
Full Name SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5
Also known as ISWI|SNF2H|WCRF135|hISWI|hSNF2H
Coordinate chr4:143513702-143557486
Strand +
Gene summary The protein encoded by this gene is a member of the SWI/SNF family of proteins. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The protein encoded by this gene is a component of the chromatin remodeling and spacing factor RSF, a facilitator of the transcription of class II genes by RNA polymerase II. The encoded protein is similar in sequence to the Drosophila ISWI chromatin remodeling protein. [provided by RefSeq, Jul 2008]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes SMARCA5P2
Bonobo Pan paniscus SMARCA5P2
Gorilla Gorilla gorilla SMARCA5P1
Orangutan Pongo abelii SMARCA5P1
Gibbon Nomascus leucogenys SMARCA5P1
Green monkey Chlorocebus sabaeus SMARCA5P1
Crab-eating macaque Macaca fascicularis SMARCA5P1
Rhesus Macaca mulatta SMARCA5P1
Baboon Papio anubis SMARCA5P1
Golden snub-nosed monkey Rhinopithecus roxellana Without Homology
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>SMARCA5P1
TTTATTTTAATTACTAGAAAAAGAAACTCTGTATTACAGAAAAGCAACTGGGTACAAGGTACCTCAAAATCACGACCTACCAAATGCAGCATAGGCACAGAAAAAGAACAGTTTAAATAAGCTGAACCCCTTATTGATGAAGAGATAGAGTTAACACAGGGATTTACCAATTGAACTCAGAGATTTTAACCAGCTTATCAAAGCTAATTAAAATGGGGTTGTGATATTGAAAATATAGCAAGAGAAGAAGAGGGAAAAAGCTTACGGGAGGTCCTTGAATACTCAACTGTGTTCTGGGAAAAACGCAATGAGCTCCAGGACATAGACAAGATTATGGCTCAGAGTGAAAGGGAGAGATAAGAATTCAGAGAATAATTTGCATCAGAAAAGCACCTGACAAAAAGATCAGATGGTACAGAGCATCTAGCACCTTTTCTTCAGCTGAGGATATCATGGTACTAGTATAACAGAGGGAAAAACTGTACTGAGGAAGAGGATCA
>NM_003601.4
GCCGGTGGAACCTAGAGCCCCGCGGAAGAGCAGAACGTTTGGGAGTGTGCAGCTCCTGGGCCCGGCTCAGGCCCGTCGCGGAGGCGCGGCGCAGGGGAGCGCTCGGGTGGGAGTCTCGCTCCTCCACCAGTTTATTGCGACGTAGCATCCAGGCCTAGGCCTCCCCGTCCATCCCCGCCGGACTCGGGCCTCTGGCAGCAGCGGGTGACGCAGACGGAACATCATGTCGTCCGCGGCCGAGCCTCCGCCACCCCCGCCTCCCGAGAGCGCGCCTTCCAAGCCCGCAGCCTCGATCGCCAGCGGCGGGAGCAACAGCAGCAACAAAGGCGGCCCCGAAGGCGTCGCGGCGCAGGCGGTTGCGTCTGCGGCCAGCGCTGGTCCCGCAGACGCCGAGATGGAGGAAATATTTGATGATGCGTCACCTGGAAAGCAAAAGGAAATCCAAGAACCAGATCCTACCTATGAAGAAAAAATGCAAACTGACCGGGCAAATAGATTCGAGTATTTATTAAAGCAGACAGAACTTTTTGCACATTTCATTCAACCTGCTGCTCAGAAGACTCCAACTTCACCTTTGAAGATGAAACCAGGGCGCCCACGAATAAAAAAAGATGAGAAGCAGAACTTACTATCCGTTGGCGATTACCGACACCGTAGAACAGAGCAAGAGGAGGATGAAGAGCTATTAACAGAAAGCTCCAAAGCAACCAATGTTTGCACTCGATTTGAAGACTCTCCATCGTATGTAAAATGGGGTAAACTGAGAGATTATCAGGTCCGAGGATTAAACTGGCTCATTTCTTTGTATGAGAATGGCATCAATGGTATCCTTGCAGATGAAATGGGCCTAGGAAAGACTCTTCAAACAATTTCTCTTCTTGGGTACATGAAACATTATAGAAACATTCCTGGGCCTCATATGGTTTTGGTTCCTAAGTCTACATTACACAACTGGATGAGTGAATTCAAGAGATGGGTACCAACACTTAGATCTGTTTGTTTGATAGGAGATAAAGAACAAAGAGCTGCTTTTGTCAGAGACGTTTTATTACCGGGAGAATGGGATGTATGTGTAACATCTTATGAAATGCTTATTAAAGAGAAGTCTGTGTTCAAAAAATTTAATTGGAGATACTTAGTAATAGATGAAGCTCACAGGATCAAAAATGAAAAATCTAAGTTGTCAGAAATAGTGAGGGAATTCAAGACTACAAATAGACTATTATTAACTGGAACACCTCTTCAGAACAACTTGCATGAGCTGTGGTCACTTCTTAACTTTCTGTTGCCAGATGTGTTTAATTCAGCAGATGACTTTGATTCCTGGTTTGATACAAACAACTGCCTTGGGGATCAAAAACTAGTTGAGAGGCTTCATATGGTTTTGCGTCCATTCCTCCTTCGTCGAATTAAGGCTGATGTTGAAAAGAGTTTGCCTCCAAAGAAGGAAGTAAAAATCTATGTGGGCCTCAGCAAAATGCAAAGGGAATGGTATACTCGGATATTAATGAAGGATATAGATATACTCAACTCAGCAGGCAAGATGGACAAAATGAGGTTATTGAACATCCTAATGCAGTTGAGAAAATGTTGTAATCATCCATATCTCTTTGATGGAGCAGAACCTGGTCCACCTTATACAACAGATATGCATCTAGTAACCAACAGTGGCAAAATGGTGGTTTTAGACAAGCTGCTCCCTAAGTTAAAAGAACAAGGTTCACGAGTACTAATCTTCAGTCAAATGACAAGGGTATTGGACATTTTGGAAGATTATTGCATGTGGAGAAATTATGAGTACTGCAGGTTGGATGGTCAGACACCCCATGATGAGAGACAAGACTCCATCAATGCATACAATGAACCAAACAGCACAAAGTTTGTTTTCATGTTAAGCACGCGTGCTGGTGGTCTTGGCATCAATCTTGCGACTGCTGATGTAGTAATTTTGTATGATTCTGATTGGAATCCCCAAGTAGATCTTCAGGCTATGGACCGAGCACATAGAATTGGGCAGACTAAGACAGTCAGAGTGTTCCGCTTTATAACTGATAACACTGTAGAAGAAAGAATAGTAGAACGTGCTGAGATGAAACTCAGACTGGATTCAATAGTCATTCAACAAGGGAGGCTTGTGGATCAGAATCTGAACAAAATTGGGAAAGATGAAATGCTTCAAATGATTAGACATGGAGCAACACATGTGTTTGCTTCAAAGGAAAGTGAGATCACTGATGAAGATATCGATGGTATTTTGGAAAGAGGTGCAAAGAAGACTGCAGAGATGAATGAAAAGCTCTCCAAGATGGGCGAAAGTTCACTTAGAAACTTTACAATGGATACAGAGTCAAGTGTTTATAACTTCGAAGGAGAAGACTATAGAGAAAAACAAAAGATTGCATTCACAGAGTGGATTGAACCACCTAAACGAGAAAGAAAAGCCAACTATGCCGTTGATGCATATTTCAGGGAAGCTCTTCGTGTTAGTGAACCTAAAGCACCCAAGGCTCCTCGACCTCCAAAACAACCCAATGTTCAGGATTTCCAGTTCTTTCCTCCACGTTTATTTGAATTACTGGAAAAAGAAATTCTGTTTTACAGAAAAACTATTGGGTACAAGGTACCTCGAAATCCTGAGCTGCCTAATGCAGCACAGGCACAAAAAGAAGAACAGCTTAAAATTGATGAAGCTGAATCCCTTAATGATGAAGAGTTAGAGGAAAAAGAGAAGCTTCTAACACAGGGATTTACCAATTGGAATAAGAGAGATTTTAACCAGTTTATCAAAGCTAATGAGAAGTGGGGTCGTGATGATATTGAAAATATAGCAAGAGAAGTAGAAGGCAAAACTCCAGAAGAAGTCATTGAATATTCAGCTGTGTTTTGGGAAAGGTGCAACGAGCTCCAGGACATAGAGAAGATTATGGCTCAGATTGAAAGGGGAGAGGCGAGAATTCAAAGAAGAATAAGCATCAAGAAAGCACTTGACACAAAGATTGGACGGTACAAAGCACCTTTTCATCAGCTGAGAATATCATATGGTACTAACAAAGGAAAAAACTATACTGAAGAAGAAGATCGTTTTCTGATTTGTATGCTTCACAAACTTGGATTTGACAAAGAAAATGTTTATGATGAATTGCGACAGTGTATTCGCAACTCTCCTCAGTTCAGATTTGACTGGTTTCTTAAGTCCAGAACTGCAATGGAGCTCCAGAGGAGATGTAATACCTTAATTACTTTGATTGAAAGAGAAAACATGGAACTAGAAGAAAAGGAGAAGGCAGAGAAAAAGAAACGAGGACCAAAGCCTTCAACACAGAAACGTAAAATGGATGGCGCACCTGATGGTCGAGGAAGAAAAAAGAAGCTGAAACTATGAATATGTTTTTGTTTCATAATCACTAACTTTAAACCAGTAGTTCTTTAATTTACGGGTCTTCATAAGATGTACTGTACAATGCTCAATTGTTATGTCATTTAAAGACATCAGGTTCATCTGTTTACTGAGCTAGAAACATAGTATGTAGTTTCACTTTTTTAAATGCAACAGCTGTGCTGAAATTTTTTTATCATTAACACTTGAAGTAATAAAATAGGCTTCATTTATTACTAAGTGTTTCATTTGATTTATTTTTCTATTGTAGTTCCATTTGTGAAGATTGTGACTTTTTGTTTATTAGCTATAATTTCTACACTTGTAAGGCTTAAAAACAAGTTAAAAAGAAAATTGCAAATAACATTTGTCCCTTTCAGTCTTCACCTAGTTGTGTAATTATTTTAATTCACTTTGCCTTTGCAGAAATTTGGGTATTTTCTTTGTAGTGCTATTGAGTCTCATCTGGAAAGATTATATAAATTGCATTCTCCTTGCTTATGTGGGTAGAATGGGAAAAGAAGGCAAGACAAAGTATACTTAAATTCTATGCATATTTCTGTTATGCTTTCTGTTTTTTTTAGTTGATTCTGAAATGAATATGCCCTATTCTTTTGAAAGAATGGCCTTTTAGTTGTATAGCCAAAGACATTTAGTATTTTCCGGTTCCTTAAGGTATTACTGTACCATTTTGTAAAAGGAAtattattattattatttttaattattTGGTAAATATTTTGTCATATGACCTTCTGAAGCAGCCACAACTTAGATAATGTCAGAACTAAGGTGATTTTTTTTTTTTAATTTTGAAAGCCCAGCCAAAATGAGGTGTGAATTTGTCATACTGTTACATTGAAATTGGTAACAAAATATATCCCCTCCCATTTGGACTTTTAGGGTAAATGAAAATTTTATTGTATTTTAAAGTAGTTTCTAAGTGTTAGCAAGACTGACTATAATTCCAGTTTCTGTTTTCTATGGACAGACCTGATAAACTGGAGACCCTAAAGCAGGAATACCCAAATTATAGTGTCAGGATTTTAGCTGTACCAGAGGCCTTTATGTGCTACACATAATTTGTATAAAATTTTATATGTGCAGATTGGGTACATAAACAGTTCTCCATTTTTCTAAGGGAATGCAATAAATGTAGCATCGTGAATAAATATAACTTTTATAATCCGTAAAGTGGTCTTTTCTTTCCATTTCTTTAATTGTTTTCTCAATTTTTATTCACTTTTTCCTTTAGGACACATTTCCCTTAATTGGATATCTTTCCCTTAAATTTCTATTAGTAGTTGTTTTCATCTGCCCACATGTAATTGAAGATTTAAAAAAAAAATTTTGATACCTGCAGTATTACTAATACTGCTTAATTTCTTGAAATGTGGAATTGCTGCTGTTAATGTCAAGCAAAACGCAGTATTTATGGCAAATTGTAAAGTAATTTGAATTTAGTGCTACCTCAAAATTAACTTTTTAAATACTATGTTAGATTCTTAACAGTTAAAGGTCTAATACATGCATGAGGAATGGTTACTTATGAAAGGAAAAAGAATTTGTAAGAGTTATCACCTCAGTTTGGAAGAAATTGAAAAAATGTAAGGCTGAAGAAAACTTACGGAGGTCACAAAAGTGATGTTTTCAAGAGGAGGAGAAACTGGGAGGGAGATACACAGTGGAAATGCAAAATGAATCAAGTATAGTGGTAGCCCTGAGAGCTTAGGGACTCAAATGGAAACTGTGTGAAGGGAAACTCACTTGAAAAAAAAGCATGAACCAGCTAGGCCCTGCCACCACTGTGTTTGGCCAAGTTCACAAATCTGTTTTAACCTGTCACTTCCCTGTCACTTCTCTGGCTTTCCTCTCCCGCTAAGCTTTTGTTTCCTGGCAGTAATTAAAATCTTCTGTCAGTGCCAcagctactactgctactggaactgccttaaccactactgctactggaactgcCTTAGCCACCTTGGTATCGTGGTTTGGCAAAGTATTGGCCTCTACCACCATAGGGCCCAGAGCTTCTGCCTCCAAAGTTTCCTCCCTTCATGGGTCCAAAATTTGAAGACTGATTGTTGTCATTGCCAAAATCATTGTAGCTTTTACCACCTCCAAAATTGCTTCAATCATTACCAAATCTATTATAGCAATCCCCACTGCCACCATATCCATCACCACCACCATGGCTGCCACCAAAGCCACCACGATCACAGAACTTGATGACTGTATTTGTGACTAATTGTATAATAGTTTCTGTTCTGTGGAAAGTAAAGCATTCCAACACAGGGTTTCAGTGTAGATTGTTTTGTTTTGTACCCATGCTGTTGATTGCTAAATGTTTTAATAATCTGATCATGATACTGAATAAATGTCTTTTTTTTTTTTTAACAACAAAGCATGAAAGATTGCTTAATTGTACATCTGACAAAGTGCTGGAGGCTATTATAAAGTGTAATTATTACTACTTTTAAgagacagggtcttgctctgtcacccaggctggagtgcagtggtgcaatcacagctcactgcaacctcaaacttcagggctcaagtgatcctcccacctcagcttcccaagtagctaggactacagataccacgcccagctaagtttttttagtttttgtagagatagggccttgctatgttgcccagtccggtctcaaacgccgacttcaggcaatcctcttgcgtcaacctctcaaagtgctgggattacatgtgtaagccTACAttccaaagtgctgggatcatagttgtgagcctacaccacacctggccTACATTTTGTTTTTCATAAAGTTGAGAGAAGCAAATCCTAAGCATAGAGTAcaagttgagcatccctaatcaaaaaatctaaaatcagaaatgctccataatttgaatgctcattagggcatttctgatttttggattagggatgctgaactgataagtataatgcaagtattctaaagtctggaaaatgctaaaaacacttctggttccaggcatttcagataaggattgctccatctgCCCTTTGAGTATTTAATATATGCCGATTGTTTGAACTAATCTGGATTTAattatataaatgattatataaatgatCTTTGGCTTAGTACCTTTCTTAATCTCGATCTTAAAAAGCATTGTAAAACACCCCTGTGGTTTTTCAGAAAAATTCTGAGTAAAAAATAAATTTCATCTTGTTCTATCCCTTTGAATCTAAAAAACAAATCTTTTTGAAAGGATGTGCTACTATATTTCAAACCAGTAGTTTTGGAGTAGAACATTGCTAAAAAAATGGGTACTAAGGAGGGTAATTTAAACAAAGTAGATTAATGACACAAGGTGGATTGATGAACTCATAAATCCAAATGAATGGAATGCTAGAAGACATGTATTAACGGAGTAGCTGTTACCAAAATATATACATATTTTGTATATGTACATAGCTGTTACCAAAATGTATCTTTGCCTGTTGGAATCTGATGTCAAGATCAAAGGTGAGGGCATCCCTCAGATGACAGATAATGGGCAAAATACATTCTTGGTGTGGAGCAGTGCTGCAGAATTAACTTCGCTGTGTACATCCCAGAATCGTTTTGGATCTGTTAAGGTTTTTATTAGAATGATTAAATAGGCTTTTGCAGCATTAACTTTACAGTAGTTACCAGAAAAGACTATGCTACAAGAACCAAAATTGAAGTAAGAAGAAAAAGACTGAAATGATATGATTCTAAATGAAAAAAATGAAGAAGTGGAATAGTTTCTCCACAGGCATAAGAGGCAAAGCATTGTTTCAGAAGTGGACTGGCACCTCACCTGAGATACTCAAGACTGGCAACATGGGTCTACATTCTTTGTTACCACAGATTCCCTTGTGTCCGGAGAGATTCCCTAGCTCTAATGACAGCTTTTTTGGGGGGTAATGAGGCTATGAGAAGATTGAGGATCTAGGTACTTGCCTTTAACTCTACAGCATACAAGGTGTGTGGCTCTTATCTCTAGGACACCAATATTTAATGTTGCATATCATGTATCTCCAGTACAAGAAGAAAGTTTATCAGAATTTAGTTAATGTTGGAAACTTTGTAATATAAACAATGTAAACACTACATTGACAAAAATATTTTATTAATACAAAGAATATGCATATAGTTTGCTTACTACAGAAATTCTTGTTTTTGATGTAGACAACCCAAAGGAGTTTTTATGTATATAGATTGTGAATAAATTGGGAAAAGAAATAGAGATAAGTAGAGATTATTTCACTTCATTAAACTTTTGAAGTCCTAA

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