Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name TFDP1P4
Plot displaying the genomic locations of a retrocopy (in chr7) and its respective parental gene (in chr13). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr7:80661991-80662585  UCSC
Coordinates (T2T) chr7:81913276-81913870  UCSC
Coordinates (hg19) chr7:80291307-80291901  UCSC
Strand -
Parental Sequence NM_007111.5
Parental seq. overlap 534 bp
Parental seq. overlap (%) 20.2%
Genomic Region Intragenic (CD36)
Retrocopy Summary TFDP1P4, located on chr7:80661991-80662585, is a retrocopy of the parental gene TFDP1. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name TFDP1
Full Name transcription factor Dp-1
Also known as DILC|DP1|DRTF1|Dp-1
Coordinate chr13:113584693-113641473
Strand +
Gene summary This gene encodes a member of a family of transcription factors that heterodimerize with E2F proteins to enhance their DNA-binding activity and promote transcription from E2F target genes. The encoded protein functions as part of this complex to control the transcriptional activity of numerous genes involved in cell cycle progression from G1 to S phase. Alternative splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 1, 15, and X.[provided by RefSeq, Jan 2009]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes TFDP1P3
Bonobo Pan paniscus TFDP1P2
Gorilla Gorilla gorilla TFDP1P2
Orangutan Pongo abelii TFDP1P2
Gibbon Nomascus leucogenys TFDP1P3
Green monkey Chlorocebus sabaeus TFDP1P1
Crab-eating macaque Macaca fascicularis TFDP1P2
Rhesus Macaca mulatta TFDP1P2
Baboon Papio anubis TFDP1P2
Golden snub-nosed monkey Rhinopithecus roxellana LOC104671369P1
Marmoset Callithrix jacchus TFDP1P1
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>TFDP1P4
GCCATAAGTCTGGTCCCAAAGGCGCTGGAGCCACACGTGACAGAAATGGCGCAGACAATTGTTGCAGGCGTGTTCATCACAACGGCAGGTTCCACGTCTAACGGCACGAGGCTCTCTGCCAGTGACCTGACCAATGGTGCGGATGAAATGCTGGCCACAAGCTCCAACAGGTCTCAGTACAGCATCTCCAGGGTGAAGACCCCGGTGTCCCAGGTTGGGGAGGATGAGGAGGACTACGATTTCGACGAGGACAACTGACTTCCTCTCCACTTCAATTTCAGCTTCAGGAAAATGTTTAGGAAAAGAAACTTCTTTTTTTAATGTGGGTTTTCTGTTTCCTTTTGGCCTACTCCCAAGAATATATTGGTAAGCTATTGAATTTAGATATGCACCTCCGATAAGCAAGGATTGTTTCCCATAGAATTAGGATGTGCTGTGGATGTGTGGTTTGATGCCAGTGTGCTAATGCAGAGCCTTCATATACTTTTTAGGATTTTGTGTTTCCGTTTTCTATTTTTCTTAAAATGCAGAGTTCATATTTGCCCCTTAAGAGTTTTTGCTGAGCTTGCTGAAGAAATTGTACTTCATCCACATA
>NM_007111.5
ACTCGGCCCAGGGCAGGGACCCCGCCACGGCCGGGACCGCCCGGCCCGGCCCCAGCCCGCGCCTCTCCGCGCCGCCCCGCGCTCCGCACCGCGCCCTCTCCGCGTCCCCGCCCGCGCGGCCGGACCGGGCAGCCAGAAAAATCATTTTTCTTCTCTGGGAAGGTGAACATTTGTAGCATTGATTTCCCGGATCTGGTAACATGGCAAAAGATGCCGGTCTAATTGAAGCCAACGGAGAACTCAAGGTCTTCATAGACCAGAACCTTAGTCCCGGGAAAGGCGTGGTGTCCCTCGTGGCCGTTCACCCCTCCACCGTCAACCCGCTCGGGAAGCAGCTCTTGCCAAAAACCTTTGGACAGTCCAATGTCAACATTGCCCAGCAAGTGGTAATTGGTACGCCTCAGAGACCGGCAGCGTCAAACACCCTGGTGGTAGGAAGCCCACACACCCCCAGCACTCACTTTGCCTCTCAGAACCAGCCTTCCGACTCCTCACCTTGGTCTGCCGGGAAGCGCAACAGGAAAGGAGAGAAGAATGGCAAGGGCCTACGGCATTTCTCCATGAAGGTCTGCGAGAAGGTGCAGAGGAAAGGGACCACTTCCTACAACGAAGTGGCAGACGAGCTGGTTGCGGAGTTCAGTGCTGCCGACAACCACATCTTACCAAACGAGTCAGCTTATGACCAGAAAAACATAAGACGGCGCGTCTACGATGCCTTAAACGTGCTAATGGCCATGAACATCATCTCCAAGGAGAAGAAGGAGATCAAGTGGATTGGTCTGCCCACCAACTCGGCTCAGGAATGTCAGAACTTAGAGGTGGAAAGACAGAGGAGACTTGAAAGAATAAAACAGAAACAGTCTCAACTTCAAGAACTTATTCTACAGCAAATTGCCTTCAAGAACCTGGTGCAGAGAAACCGGCATGCGGAGCAGCAGGCCAGCCGGCCACCGCCACCCAACTCAGTCATCCACCTGCCCTTCATCATCGTCAACACCAGCAAGAAGACGGTCATCGACTGCAGCATCTCCAATGACAAATTTGAGTATCTGTTTAATTTTGACAACACATTTGAAATCCACGATGACATAGAAGTGCTGAAGCGGATGGGCATGGCTTGCGGGCTGGAGTCGGGGAGCTGCTCTGCCGAAGACCTTAAAATGGCCAGAAGTCTGGTCCCCAAGGCTCTGGAGCCATACGTGACAGAAATGGCTCAGGGAACTGTTGGAGGCGTGTTCATCACGACGGCAGGTTCCACGTCTAACGGCACAAGGTTCTCTGCCAGTGACCTGACCAACGGTGCAGATGGGATGCTGGCCACAAGCTCCAATGGGTCTCAGTACAGCGGCTCCAGGGTGGAGACTCCGGTGTCCTacgtcggggaggacgacgaggaggacgatgacttcaacgagaatgacgaggacgactgacgTCCTCCCCACTTCAGATTCGGCTTCAGGAAAACGTTTAGCGAAAAGAAACTTTTTTTTTAATGTGGGTTTTCTGTTTCCTTTTGGCCTACTCCCAAGAAGATATTGGTAAGCTATTGAATTTAGATATGCACCTCTGATAAGCAAGGATTGTTTCCCGTAGGATTAGGACGTGCTGTGGATGTGTGTTTTGATACCAGTGTGCTGATGCAGAGCGTTTATTTACTTGTTAGGATTTTGTGTTTTCATTTGCTATTTTTCTTTAAGTGCAGAGTTCATTTTTGCCCCTGAAAAGTTTTTGCTGAGTTTGCTGAAGAAATTGTATTTCAACCACATCCATGAAAATAAAACACCTCCTGTTGTGGATGGTGAGCCCCTGATGCCGCTTATTTGCCGTGAGTTTGGACGGCACCCCTGCTGGCGGATAGCAAGACTCTGTGGAGTTTGTTCAGTGGTACGGTGTCCAAGCAAACAGCAGAATGCAACTTTCTAAACAGCCCCAAGCAAACAGCAGAATTCAACTTTTTAAACAATAAACACCATCAACCTTATTGACTTTATTGTCCCTTAAATTATATTGACTGTTGTGATTCCATCAAGTTTGTACACTCTTTTCTCTCCCTGTTTTGCAGCAACAAATTGCGAAGTGCTTTTGTTTGTTTGTTTTCGTTTGGTTAAAGCTTATTGCCATGCTGGTGCGGCTATGGAGACTGTCTGGAAGGCTTGGAATGGTTTATTGCTTATGGTAAAATTTGCCTGATTTCTTACAGGCAGCGTTTGGAAACCTTTTATTATATAGTTGTTTACATACTTATAAGTCTATCATTTAAAGACATGTACTGAAACAAATGTATTTGTTTCATAAGCATCTTCCTGTAATCTATTATAAAATTGAAATTAAATATAGAGAATGTTTTAACAATTTTTTAACTCAAAATTTGTCAATCATTTTTAATAGTTCTTTTTTTATAAAAAGAAAAAGGAATTTAAGGACAGGCAGTAGTCTCTTTTAAAATTTATTCACAAAACCCATTAACTGCACAGTTGCTATTAGCTGCCTGTTCTAAAACGATAGTCTTTTTATTGAAACACAAATAAACTTTTCTGTAATATTTTATGGTATATAAAGAGACTTTAATTGTTTGACTTGTTTAACTTGGCACTGTTAGTTTTTATTAATAAAACGCGCATGGGCATTTTAAACAA

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