Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name FAM183AP1
Plot displaying the genomic locations of a retrocopy (in chr8) and its respective parental gene (in chr1). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr8:29921972-29922129  UCSC
Coordinates (T2T) chr8:30200818-30200975  UCSC
Coordinates (hg19) chr8:29779488-29779645  UCSC
Strand +
Parental Sequence XM_005270875.5
Parental seq. overlap 142 bp
Parental seq. overlap (%) 9.9%
Genomic Region Intergenic
Retrocopy Summary FAM183AP1, located on chr8:29921972-29922129, is a retrocopy of the parental gene CFAP144. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name CFAP144
Full Name cilia and flagella associated protein 144
Also known as FAM183A
Coordinate chr1:43142959-43156396
Strand +
Gene summary Predicted to be located in centrosome and ciliary basal body. Predicted to be active in ciliary base. [provided by Alliance of Genome Resources, Apr 2022]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes FAM183AP3
Bonobo Pan paniscus FAM183AP3
Gorilla Gorilla gorilla FAM183AP4
Orangutan Pongo abelii FAM183AP4
Gibbon Nomascus leucogenys FAM183AP2
Green monkey Chlorocebus sabaeus FAM183AP1
Golden snub-nosed monkey Rhinopithecus roxellana FAM183AP6
Marmoset Callithrix jacchus FAM183AP3
Crab-eating macaque Macaca fascicularis Without Homology
Rhesus Macaca mulatta Without Homology
Baboon Papio anubis Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>FAM183AP1
ATCACCAGGAAGCCCATGTCTCTGCATGATAACCTGGAGAAACCTACAGATGCCAGGCTTCTGAATCTCATTCACCATGCTTCCCAGGGATCAAGGAAGAAATACCCAGAGATACAGACTGAAAAATCAGGAAACTGGATGGGATTCAGAGCCCTTGG
>XM_005270875.5
caagctggtctcgaactcctgacctcaggtgatccacctgcctcagcctcccaaagtgctgggattacaggcgtgagccaccgtgctcggcGATTCTTTTAAAATAAACTACAttatttaaggtatctagcagactcaaattcatagaaacaaaaagtgaaatgccaggggctggagagaagggaaaagggaaacttgttgtttaatgggtgtgaaaaagttctggagattggtttcacatagtttgaatatacttaatactactgtactgtaatacttaaaaatggctaagatggtaaaattatattacgtgcattttaaacacaaacattaaaaaTAAACTATAAAGTCAACAAGTTCCTTAATTAGGAAAGGTTTATTCTGTCAATATTATCACATTGGTAATCTTGGTCACACTGGCCAGAACGTTTTCTCAGAGAGGAAACCTCCGGTTTTTTTGTGAGGTTTTGATTCTGGGCATCTGCTTTAAGGTGGGAGAGGTTTCTGACTCCTTCCAAAAGCTTTTTTAGGAAATGATTGGCCAAGGTGAGGTCCAATCATCTGTCCCTTACCTCCTGGGTCTGCCCCTTGCCGGGAAGCCCTTTCCTGGCGGTATCCAGGGGACCTTCTAGTAACCAGCCGGGCCTGAGGAGCTGGGGCAAGTGAGTACAGTGCCAGAATAGGGCGGGGCGCGAAATAAGATCCCGACCGGCGGGCGCGGGGCGGGGCGATGCAGGCAGGGTAAGGGGCTGGCAGAGTGAGACCCGCCCCGACCGGGCAGCACTACCCGAGCGCTGTTGCCTGGAGACCACGGGACGCCGTTGCCTGGAGACAGCGGGGACGCGTTGCCTGGAGACTGTGGAAGGCCCAGGCAAGAGGGCGCGTGGCAGCCCAAGGCCATGGCGGGACACCCAAAAGAGAAGGTGATTCCAGATGAGGTCCATCAGAACCAGATCTTGCGGGAACTGTACCTCAAGGAGCTACGAACCCAGAAACTCTACACGCAGTATCACGTGAATCCCCTCCGCAAGATTCATACAGTCACCAGGAAGCCCATGTCTTGGCATGATAACCTGGAGGAACCTGCAGATGCCAGGTTTCTGAATCTCATTCACCATGCTGCCCAGGGACCAAGGAAGAAGTACCCAGAGACACAGACTGAAAACCAGGAAGTTGGATGGGACTTAGAGCCCTTGGTAAGCGTGGCTCCTTCCTCAGGAAATACGAGGAAACACAGCAGCAATATCAACCCAGAACGCCATGACCGCAGGCTGAATCACTTCAGGGTCTGCAGTGACATCACTCTGTACAAGGCTAAAACGTGGGGCTTAGGAGATGATCACCACAAGTAGCATCCCAGCGGATGAGCCCATCTGTGGATCTAATGCCTTAAGTGTGCACAGCCCAGAGAAATAAAATACTACTTTAAAACGAA

Publications

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