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Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name PSMA2P2
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Plot displaying the genomic locations of a retrocopy (in chr8) and its respective parental gene (in chr7). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr8:93939302-93942893  UCSC
Coordinates (T2T) chr8:95064384-95067975  UCSC
Coordinates (hg19) chr8:94951530-94955121  UCSC
Strand -
Parental Sequence NM_002787.5
Parental seq. overlap 590 bp
Parental seq. overlap (%) 38.7%
Genomic Region Intergenic
Retrocopy Summary PSMA2P2, located on chr8:93939302-93942893, is a retrocopy of the parental gene PSMA2. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name PSMA2
Full Name proteasome 20S subunit alpha 2
Also known as HC3|MU|PMSA2|PSC2
Coordinate chr7:42916861-42932174
Strand -
Gene summary The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. [provided by RefSeq, Jul 2008]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes PSMA2P2
Bonobo Pan paniscus PSMA2P2
Gorilla Gorilla gorilla PSMA2P2
Orangutan Pongo abelii PSMA2P2
Gibbon Nomascus leucogenys PSMA2P2
Green monkey Chlorocebus sabaeus PSMA2P2
Crab-eating macaque Macaca fascicularis PSMA2P2
Rhesus Macaca mulatta PSMA2P1
Baboon Papio anubis PSMA2P1
Golden snub-nosed monkey Rhinopithecus roxellana PSMA2P2
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

The Genotype-Tissue Expression project - (GTEx)

Massive Mining of Publicly Available RNA-seq Data from Human and Mouse - (ARCHS4)

Related Sequence

>PSMA2P2
ATTTTACTATTTTACAGTTTGATTCTTTTTTTCAATACAGCCATCTTAACACCTCAAGGAAAGCTTTGAAGGGCAAATGACAGAGGATAACATAGAAGTTGGAATCTGCAATGAAGCTGATTTGGGAGGATTACTCCAACTGAAGTTAAGGATTACTTGGCTGTCATAGCACAACAATGAAATGACTGAACAATCTGGAATTTCAGATAATCTATCTACTTAAACATGTTTATCCAAGAACCCATTTCCATAGCTTGGCTGGTACGGAAAGTAGTTTCTGTAACCCAAGAATACACTCACTCAAGTGGTGTTTGTCCATTTGGAGTTGATTTATCTGTGGTTGGAATGAGGGATGACCATGTTTATTTCAGTCAGATCCATCCAGAGCTTACTTTGCTGGAAAACCACAGCAAAGAACTATGTGAATGGGAAAATGCTGAGAAAAGATATAATGAAAATCTGGAACTTGAAGATGCATTCATATAGCGGCTCTCCAGGTAAAGATGGCAGAGCACAGGTACAGCTTCTTGCTGACTACACTCAGCCCATCTGGTACACTTGTCCACACTGAATATGCTTTAGCTGCTGTAGTGGGAGGAGCCCCTTCAGTGGGAATTACAGCTGCAAATGGTGTGGTATTAGCACTGAGAAGACACAGAAATCCATTCTGTATGATGAGCAAAGTGCACACAAAGTAGAACCCATTACCAAGCGTAGCGGTTTGGTGCACGGTGGTGCGGATCCAGATCAGAGTGCTTGTGCATGGAATTCAAAAACAGCTCAGCAATACTGTAATATCTCCGTACCAAt
>NM_002787.5
GGCTCTTCGGGTAAAGATGGCGGAGCGCGGGTACAGCTTTTCGCTGACTACATTCAGCCCGTCTGGTAAACTTGTCCAGATTGAATATGCTTTGGCTGCTGTAGCTGGAGGAGCCCCGTCCGTGGGAATTAAAGCTGCAAATGGTGTGGTATTAGCAACTGAGAAAAAACAGAAATCCATTCTGTATGATGAGCGAAGTGTACACAAAGTAGAACCAATTACCAAGCATATAGGTTTGGTGTACAGTGGCATGGGCCCCGATTACAGAGTGCTTGTGCACAGAGCTCGAAAACTAGCTCAACAATACTATCTTGTGTACCAAGAACCCATTCCTACAGCTCAGCTGGTACAGAGAGTAGCTTCTGTGATGCAAGAATATACTCAGTCAGGTGGTGTTCGTCCATTTGGAGTTTCTTTACTTATTTGTGGTTGGAATGAGGGACGACCATATTTATTTCAGTCAGATCCATCTGGAGCTTACTTTGCCTGGAAAGCTACAGCAATGGGAAAGAACTATGTGAATGGGAAGACTTTCCTTGAGAAAAGATATAATGAAGATCTGGAACTTGAAGATGCCATTCATACAGCCATCTTAACCCTAAAGGAAAGCTTTGAAGGGCAAATGACAGAGGATAACATAGAAGTTGGAATCTGCAATGAAGCTGGATTTAGGAGGCTTACTCCAACTGAAGTTAAGGATTACTTGGCTGCCATAGCATAACAATGAAGTGACTGAAAAATCCAGAATTTCAGATAATCTATCTACTTAAACATGTTTAAAGTATGTTTTGTTTTGCAGACTTTTTGCATACTTATTTCTACATGGTTTAAATCGACTGTTTTTAAAATGACACTTATAAATCCTAATAAACTGTTAAACCCACCTTCCAGCCTTTTAGGAGTTGCTAAAATTTTAACAGTTATTTCCTGCTTTTTATCACAGTTGATTTCTGAAGACTACATTGCCAAGCAGAATGATGAAATGACTTTTTCGTTGTCAGGCAATTTTGGTTAAGTCAAATCTTAATGCCCTCTTCGCTATCAGATGTTGCCTGTGTTTCCATAAAGCAAAATGCTGATTTTGGTAAAAAACATGACTGCTTCTAGAGCTGGGAGGATCTGCAGACTTTCACGGATTCATGGAACAAGAAAAGAAGCATAGGTACTTTTAGGTGCCATTAGGTATTGATCAGTGAAATCCTAGGGTGCTCTATGAGATTGTACTAGGCCTATGAAGAGTGGTAAGCCAAATAGGTCTCCATGGGAGATACATTATGTAAATAAATAAACAATGGTTTGCTGGTTCCTGTTGGTGTCTCCACAAGTAGGTAAACATGTTTAAAGGAACCCGGGTTCTTAGATTTTGTTAGACTTTTTAAACTCAAGGATGAGCATAAGTGCTTGAAATAAAATGCTAATACTTAAGTGTCAAAA

Publications

PMID - Link Title
No publications available for this retrocopy