Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name RBPJP7
Plot displaying the genomic locations of a retrocopy (in chr9) and its respective parental gene (in chr4). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr9:62601059-62604850  UCSC
Coordinates (T2T) chr9:39751699-39755486  UCSC
Coordinates (hg19) chr9:46912360-46916151  UCSC
Strand +
Parental Sequence NM_001374403.1
Parental seq. overlap 3487 bp
Parental seq. overlap (%) 59.5%
Genomic Region Intergenic
Retrocopy Summary RBPJP7, located on chr9:62601059-62604850, is a retrocopy of the parental gene RBPJ. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name RBPJ
Full Name recombination signal binding protein for immunoglobulin kappa J region
Also known as AOS3|CBF-1|CBF1|IGKJRB|IGKJRB1|KBF2|RBP-J|RBP-J kappa|RBP-JK|RBPJK|RBPSUH|SUH|csl
Coordinate chr4:26163458-26435131
Strand +
Gene summary The protein encoded by this gene is a transcriptional regulator important in the Notch signaling pathway. The encoded protein acts as a repressor when not bound to Notch proteins and an activator when bound to Notch proteins. It is thought to function by recruiting chromatin remodeling complexes containing histone deacetylase or histone acetylase proteins to Notch signaling pathway genes. Several transcript variants encoding different isoforms have been found for this gene, and several pseudogenes of this gene exist on chromosome 9. [provided by RefSeq, Oct 2013]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes Without Homology
Bonobo Pan paniscus Without Homology
Gorilla Gorilla gorilla Without Homology
Orangutan Pongo abelii Without Homology
Gibbon Nomascus leucogenys Without Homology
Green monkey Chlorocebus sabaeus Without Homology
Crab-eating macaque Macaca fascicularis Without Homology
Rhesus Macaca mulatta Without Homology
Baboon Papio anubis Without Homology
Golden snub-nosed monkey Rhinopithecus roxellana Without Homology
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>RBPJP7
cGTCATTGAAATTATAAGACTATCATTCAAATGGAAGCATTACAGTTCTTTGGAAACATTATTATTTCAAAATGAAGGAGAATGATACAGATACACTGGCTGAGGTGTTTTGAGGTGCATTGAAAAGTTCCAAGCTGTTACTTACCTTAACATGTTCTTGAGGTACCATGGCATGGATTAAAAGGAAATTTGGTAAGTGGCCTCCATTTAAACGACTTACTAGGGAAGCTATGTGAAATTATTTAAAAGGGTAAGGGGATCAAATAGTACTTAGCCTTCATGCAAAAGTTGTACAGAAGTCATATGGAAATGAAAAAAGGTTTTTTTTGCCCTCCCCCTTGTGTATATCTTATGGGCAGTGGATGGAAGAAAATAAAATAACAAATGAAATGCGATGGTTGTTCTGAACAAGGGTCTCAACCAAGTGCATTTATTGGCATAGGAAATAGTGACCAAGAAATGCAGCAGCTAAACTTGGAAGGAAAGAACTATTGCACAGCCAAAACATTGTACATATCTGATTTAGACAAGCAAAAGCACTTCATGTTGTCTGTAAAGGTGTTCTATGGCAACAGTGATGACATTGGTGTGTTCCTCAGCAAGTCGTCCAAACCTTCCAAAAAGAAGCAGTCATTGAAAAATGCTGACTTATGCATTGCCTCAGGAAAAAAGGTGGCTCTGTTTAATCGACTACTATCCCAGACAGTTAGTACCAGATACTTGCACGTAGAAAGAGGTAATTTTCATGCTAGTTCACAGCAATGGGGAGCATTTTACATTATTCTTGGATGATGATGGATCAGAAGGAGAAGAATTCACAGTCTGAGATGGCTACATTCATTATGGACAAACAGTCAAACTTGTGTGCTCAGTTACTGGCATGGCACTCCCAAGATTGATAATTAGGAAAGTTGATAAGCAGACCACATTATTGGATGCAGATGATCCTGTGTCACAACTCCATAAATGTGCATTTGACCTTGAGGATACAGAAAGAAAGTACTTATGCCTTTCTCAAGAAAGAATAATTCAATTTCAGGCCACTCCATGCCCAAAAGAACCAAATAAAGAGAAGATAAATGATGGTGCTTCCTGGGCAATCATTAGCACACATAAGGCGAAGCATACATTTTATGAGAGAGTGGGCCCTGTCCTTGCCCTGGTCATGCCTCCGCCTGTCGTAGAGAGCCTTAAGTTGAATGGCGGTGGGGACGAACCAATGCTTGAACTTACAGGACAGAATTTCACTCCAAATTTACAAGTGTGGTTTGGGGATGTAGAAGCTGAAGCTATGTACAGGTGTGGAGAGAGTATGCTCGTGTTGTCCCAGACGTTTCTGCATTCTGAGAAGGTTGGAGATAGGTCCAGCAACCAATACAGGTTTCAGTAACTTTGGTCCGAAATGATGGAATCATATATTCCACCAGCCTTACCTTTACCTACACACCAGAAGCAGGGCCGCGGCCACATTGCAGTGTAGCAGGTGCCATCCTTCAAGCCAGTTCAAGCCACGTGCCCCCTAATGAATTAAACACAAACAGCGACGGAAGTTACACAAACGCCAGCACAAATTCAACCAGTGTCACATCATCTACACCAACAGTGGTATCCTAACTACCGTCTTTTTGCTAAGACTTAAACGGACTTGAGTGCAGCAAAAAGTTGACAAAAAAGGAGAAAAAAATGAACAGTCTTTTGTGGTTTATTGGGAAAACTTTTCACACCAGGTGATACTATTCTAAAACCCCACTATCTATCTGCAAGTGCTGATTTGAAATGCAGAAGCCACAGTAAAACAAAAAAACATCAAAATGTAAAAACTTGGAAATTAATTTTTTCAGCTGTTTTtTTTGTTTGGTTTTGTTTAAGTGGGCAAGAAGTAAATAATGTGGCTGGAATACAAGTTGAACAAACTAGAAGACATAAATCTAACATAGTTTTTATGGACCAAGTAACTTGTATATTGTATAAGCTTTAGTAAAAGGTACATTTTCACATATTCACCATACCCTTTTTTATATCATGGTATTATAGTACATCTTGTCACCAAAGAGGTTGTTCTCTTCCCCACTCACCTTTGAGCTTTTGCTTTAAAATACATTCAGGTTCCAAGCCTGGCCATGCTTGCTTAATCTAATTATCATGTTCTTCCAAGTTTTTTTTTGGTCCGAGGCTAGAGCTTTTTTTTTTTTTTCCAGCTGAAGTCTTACGACTTTTCGTGAGTCAAAATTGTTTGGATTTCAGCAAGTCAAATCTTGTGAAGGCCTACATTTTTTTTTAAGATTATGTGAAGTCTGTGCAAAAGCTTTAAAAAGCTGCCTCTGCCTTGCCTGCAACACATGCAATGTATGTTAACTTAGTCTCTCTTCGCAGACACTGTTGGTAGTTATTTCTGCATTTTCCTTTTTTTAAAAAAAAGTATTTCTAGTGGTTATCCAAGAGGTTCTAACATTCACATGCAATTTGGTGTGGCCATTTTGCCATAAATGAGTTAATAGCGCAAAACATGTTGATATTTGAAGTGTTCTCTCTCCTTTTCCCATAACGTAAATACATTATGTGTGTTCCAGGATTTGTTCAGGTTTTTCCCCGCTCCTGATCTTGTACATAACTTGTATTACGTATAAGTTAAACATTTCATTTTGAACTTGGAATGTTCCCAGTGATTTCATCCAGCAGAGTATTTTCTGCCTTGTTGGCAAGTGACAAAAAATATCATGAGAAGCATCTGCTACCAGTTGGGAGATGGTGCCCTTATGGTAGAATGAGGAAGATCTCAGCAAAAGCATGTTTTATTAACTTTACTTTTTGGGGGTGTTGGAGGGGGTAGCCTAGGCCAGAACATCATTGTAATCTTAAAACATAAGATGCTTTTATTAGATGATCAACTAAAATAGCTGGAAGACAGTACTTTAGAAACAGATAGTTGTAAGATTATGAAATGCAAATGTAACTTGTGTTTTTATTTTTCTTTTCCCTGCCTTTTTTGTTTGTTTTCTCTTCTCCAGTACTGAGCATCTCCACAAATGTCTCCTAACTCAGAAAATGTTTCTTTTCCTTTCAGCTGAGATTTGGTTGCATTCAGGGTTGTACATTGGCCTTGCATGCGAAACTCGGCAGTTGTACCTTGCTTTCATTCCTGAACTTCGCTTAGCTTTTGTTCGGATTCTTCGAAATTGCAGCAGACTCTTTGGGCTACATTTAGTACAAGAACCACGTGCATAATATGATACGGCACAGTCTAGTAATACAATCATCCTTCTTAGAGTAAAAACTACCTCTAGATTGTGGTAAGCTTTTACTGTCCCATAAAACAGGAGCCACGGTAATTTATGAATGCAAAACTGTAACTTCCTGCAGTGTTTCCATACAGAACATTGTCTTTCTGGTTTCCTGGGCTATTTTGAAAAAATTTTCATTAATAGACTTTTCAGAAATTATTATTAGTAGCATTTTTTTCCAGCTTTGCTGTTTTCATCACTCATTCTTTGCTCAGACTCCAGCATTCAGTACCGTGTTGGTCCAGATGTAGGTTTATATGCTCATTTTTAGCTTATTTCTTGTACCTTGCAGCACACTCTACGCACTCAGCCCTTAAGGGGTTTACTTTACAAACTGTGTGCCTGTAAGATGTATTAGCAATAAGATAGAAAATTGAGCAAGTTTATACCATAATTTTGTAGAAAAAAAGAATCTGCTCAATTCCATATTTCATCCATGAAAAACTTGCAATACGAGCAGTTTCAAGGAATAA
>NM_001374403.1
GTGTTTGTTATTGTGAATCCCTAAGGGTGACTGTTTTTTCAGCAGGGCGAGTTAGGACGGCACAAACTGAGAGTTTCTGTTCTGTCATTGAAATTATGAGACTATCATTCAAATGGAAGCATTATAGTTCTTCGGAACCATTATGATCTCAAAACGAAAGGAGAATGATACAGATACACTGGCTGAGGTGTTTTGAGGTGCATCGAAGTGTTCCAAGCTGTGACTTACCTTAACATGTTCTTGAAGTACCATGGCGTGGATTAAAAGGAAATTTGGTGAGCGGCCTCCACCTAAACGACTTACTAGGGAAGCTATGCGAAATTATTTAAAAGAGCGAGGGGATCAAACAGTACTTATTCTTCATGCAAAAGTTGCACAGAAGTCATATGGAAATGAAAAAAGGTTTTTTTGCCCACCTCCTTGTGTATATCTTATGGGCAGTGGATGGAAGAAAAAAAAAGAACAAATGGAACGCGATGGTTGTTCTGAACAAGAGTCTCAACCGTGTGCATTTATTGGGATAGGAAATAGTGACCAAGAAATGCAGCAGCTAAACTTGGAAGGAAAGAACTATTGCACAGCCAAAACATTGTATATATCTGACTCAGACAAGCGAAAGCACTTCATGTTGTCTGTAAAGATGTTCTATGGCAACAGTGATGACATTGGTGTGTTCCTCAGCAAGCGGATAAAAGTCATCTCCAAACCTTCCAAAAAGAAGCAGTCATTGAAAAATGCTGACTTATGCATTGCCTCAGGAACAAAGGTGGCTCTGTTTAATCGACTACGATCCCAGACAGTTAGTACCAGATACTTGCATGTAGAAGGAGGTAATTTTCATGCCAGTTCACAGCAGTGGGGAGCCTTTTTTATTCATCTCTTGGATGATGATGAATCAGAAGGAGAAGAATTCACAGTCCGAGATGGCTACATCCATTATGGACAAACAGTCAAACTTGTGTGCTCAGTTACTGGCATGGCACTCCCAAGATTGATAATTAGGAAAGTTGATAAGCAGACCGCATTATTGGATGCAGATGATCCTGTGTCACAACTCCATAAATGTGCATTTTACCTTAAGGATACAGAAAGAATGTATTTGTGCCTTTCTCAAGAAAGAATAATTCAATTTCAGGCCACTCCATGTCCAAAAGAACCAAATAAAGAGATGATAAATGATGGCGCTTCCTGGACAATCATTAGCACAGATAAGGCAGAGTATACATTTTATGAGGGAATGGGCCCTGTCCTTGCCCCAGTCACTCCTGTGCCTGTGGTAGAGAGCCTTCAGTTGAATGGCGGTGGGGACGTAGCAATGCTTGAACTTACAGGACAGAATTTCACTCCAAATTTACGAGTGTGGTTTGGGGATGTAGAAGCTGAAACTATGTACAGGTGTGGAGAGAGTATGCTCTGTGTCGTCCCAGACATTTCTGCATTCCGAGAAGGTTGGAGATGGGTCCGGCAACCAGTCCAGGTTCCAGTAACTTTGGTCCGAAATGATGGAATCATTTATTCCACCAGCCTTACCTTTACCTACACACCAGAACCAGGGCCGCGGCCACATTGCAGTGCAGCAGGAGCAATCCTTCGAGCCAATTCAAGCCAGGTGCCCCCTAACGAATCAAACACAAACAGCGAGGGAAGTTACACAAACGCCAGCACAAATTCAACCAGTGTCACATCATCTACAGCCACAGTGGTATCCTAACTACCGTCTTTTTGCTAGGACTTAAACTGACTTGAGTGTGGCAAAAAGTTAACAAAAAAGGAGAAAAAATGAACAATCGTTTGTGGTTTCTTGGGAAAACTTTTCATACCAGGTGATACTATTCAAAAACCCCGTTGTCTCCCTGCAAGTGCTGATTTGAAATGCAGAAGCCACAGTaaaaaaaaaaaaaaaaaaaaaaaaaaagaaaaaaaaatcaaaaTGTATAAATATTGGAAATCAAGTTTTTCAGCtgttttgttggttggttggttggtttttgtttggttTTGTTTAAATGGGCAAGAAGTAAATAATGTGGCTGGAATACAAGTTGAACAAACTAGAAGACACAAATCTAACATAGTTTTTATGGACCAAGGAACTTGTATATTGTATAAGCTTTAGTAAAAGGTACATTTTCACCATACCTTTTTTTATATCACGGTATTATAGTACACCTTGTTACCAAATAGGTTGTTCTCTTCCCCACCCACCTTTGAGCTTTTGCTCTAAAATACATTCAGGTTCCAAGCCTGACCATCCTTGTTTAATCTATCATACTCTTCCAGGTTTTTTTTTTTTGGTCTAAGGCTGGAACTTTTTTCTTTTTTTTCAGCTGAAGTCTTATGACTTTTCATGAGTCAAAATTGTTTGGATTTCAGCAAGTCAAATCTTGCAAAGGCCTGCATATTTTTTTTAAGATTATATGAAGTCTGTGCAAAAGCTTTAAAAAAATGCCTCTGCCTTGCCTGCAATACATGCAATGTATGTTAACTTAGTCTCTCTTCTCAGACACTGTTGGTAGTTATTTCTGTGTTTTCCTTTTTTTAAAAAAAAATATGGACTTATTGTGGTTATCTGAGAGGTTCTAACATTCACATGCAATTTGGTGTGGCCATTTAGCTATTAATGAGTTAATGGCGCAGAACTTGTTGATATTTGAAGTGTTCTCTCCCCTTTTCCCATGACGTAAATACATAGGTGTGTTCCAGGATTTGTTCAGGTTTTTCCCCCCTCCTAATCTTGTACATAACTTGTATTATGTGTAAGTTAAACATTTTATTTTGAACTTGGAATGTTCCCAGTGATTTCATTCAGCAGGGTATTTTCTGCCTTGTTGGCAAGTGACAAAAAATATGGGAAGTATTTGCTACCAGTTGGTAGATGGTGCCCTTAATGGTAGAATGAGGAAAATGTCCGCAAAAGCATGTTTTATTATCTTTACTTTTTTGGGGGGTTGGAGGGGGTAGCCTAGCCAGAACATCATTGTAATCTTAAAACATAAGATGCTTTTATTAGATGATCAACTAAAATAGCTGGAAGACAGTACTTTAGAAACAGATAGTTGTAAGATTATAAAATGCAAATGTAACTTATGTTTTCATTTTTTTCTCTGCCTTTTTTGTTTGTTTGTTTTCTCTTTTCCAGTACTGAGCATCTCCACAAATGTCTCCTAACTCAGAAAATGTTTCTTTTCTTTTCAGTTGAGATTTGGTTGCATTCAGGGTTGTAGGTTGGCCTTGCTTGCTAACCCCGCCGGTTTTACCGTGCTTTCATTCCTGAACTTTGTTTATGCCTTTGTTTGGTTTCTTCGAAATTGCAGCAGACTCATTGGGCTACATTTAGTACAGGAACCACGTGTGTAATGTTATACAACACAGTCTAGTAATACAATCATCCCTCTTAGAGTAAAAACTACCTCTAGATTGTGGTAAGCTTTTACTGTCCCATAAAACAGGAGCCACAGTACCTTATGAATGCAAAACTGTAACTTCCTACAGTGTTTCCCTACAGAACATTGTCTTTCTGGTGTCCTGGGCTGTTTTGAAAAAGTTTCCATTAATAGACTTTTTAGAAATTATTATTAGTAGCATTTTTTTTCCAGCTTTGCTGTCTTCATCACTCACTCTATGCTCAGACTATGCCACTGTAAATATTCTTCCTAACATCTTTAAATCGCCTTTTCCTCAGTTTTCAAGGGGAAGGTCATTTGTAAAGCACGTTAGGTGGTTAAATCAGTTATTGCGGTTTTCTCTTACTGCAAGCCTTTTTAATCACCCCCAGGCTGCATTTTATTCTATATCGCCTTTTTTCTTCAAATCTGCTCCAATCACTCACTTCTCTCTTATAAGCTAATCCTGCCTCACACCTTAAATCTGTTTCAGTGATCAAGGGCAGAACTCATTGTGGCCTTATCTTTCTTTGTTGTAATTGTTCACTGTCTCTTTCTTACAGACCACTTATTTCTGAGTAGTAGTTATTCCTCTCTATGGAGTCATGGCAGGAATCATTACACAGTGCTTTTGTTCAGAGCATGGACATGTTCCTAGTGCTGCTTTGCTTTAACGGCCACAAGTTTCCTCCACTTCCTAGGTTTGGTATTTAGTTAAGGAATCATATTAAATTAACCAATAACAAAAGAGATACTTTTGAAGAACAAACTATTCCTTACCCATTTTTGTAGCTCAAAAATAATTTTTCAAGTTCATGACCTTATTAAAATGAACTTGTGTTTTTTTAACAAACATGTATGTTTTATTTTGATAGTTTCTTTCCGTAAGATAATTGAAATATTATACTGTAAACCCTTTTCTTTTCTTTTTTTGAAAAGTCCAAGAATGTACTTATACAGGCATTTTTCCCCACCTATTTTTGGCCATTCTCATACCACAGACTAAAGAGTGAAATGATTTGTCCATTGTAGCTTATTGTTTATCAGTAGTTCTTTTGTCAGCTGCTTACATTTTTTCTTTCATGGTTTTGTGAATCATTTTCAGTATGTAATTTATAGGAACCTTGTCCTCTGGTTATAGTAGACTGTGTGCCCTCCTCCAGTGATGGCATTATTAGACATGCTGGTCATTTACCCTCAGAAAGACTCTCTTATTAGAATGGTGAGTGCTTCAGTTATAGTATGTTTGAATTTTTAAAAAATTCTGTTTTAGAAATGTATCTTATGCTCTCATGACTATGCAGTTTCTAAACATACACATAGAAGCTGAGTCTCTGATCCAATATGTTTTTATTTGTTCCATTTAATTTATCACATAGATTGGGAAGGCAAGCTAAAAGCCTTAAAAATGCCCTTTATATTTTGAGTGATTTCAGCGTTGAACACTAGTATACTATCTAAATTTGCTGCTCACTTTCTTTAAACTGTGGCAATTAAAGGCATGTTTATACATGACTTAATCGTGAAATGTTTGTCACTCTTACTGCACAGACTTATCTGCAATCATAACTGGTTAGtttttttgttttgttttgttttattgtttttAATGAAACTGGTACCATCTGTGCTTTCACAAAAAACTTCCAATGCCATTTTTGAGAACTAACCTAACTAGTCATGCTAACCAGAAAATCCACTGGGGAGGAGGTTCCTTTTGAAACAAAATGCTGTTCAGTTAGTAACCAAGTTACTTTGATTGCAAAAGCAGCTGTGTTTCTGATAAGTACTGAACAAATGTGTGTAATTTTCTGTGCCAGACTTATGACTTTGTTTTCAAGCACTGTAATGTGGGATGGATGGTTAGAAACAATAATATATTAGGGTTTCTGTTTAACCCTTTCAGGACTGAACTGTATCTCCTTTTGTTAATTTTCCCCTGTGTTGTGATAAATGTTTGCCAGCATTCAGTACTGTGTTGGTCCAGATGTAGGTTTATATGCTCATTTTTAGCTTATTTCTTGTACCTTGCAGCATGCTCTACGCATTCAGTCCTTAAGGGGTTTATTTTACAAACTGTGCGCCTGTAAGGTTTATTAGCAATAAGATAGAAAATTGAGCAAGTTTATACCATAATTTTGTAGAAAAAAAGAATCTGCTCAGTTCCATATTTCATCCGTGAAAAACTTGCAATACGAGCAGTTTCAAGGAATAAATAAAAAGGAAATGTAAACCATTGTAAAAGTCTTCTGTCGAATGTGCCTGATGCATGTATTATCGTCTTTTATTTCAGAATACTTCATAAAGATAAAATTAAATTCTATATTATAGTTGGTGTATTTACAATCTTACCATGTACATCACATCAAAGTGATAGCTCTACTAATTTAATTTCCTTGTCAATGTTTTTAACTATATAGTGCTTTAAAGAGATTTTTTTTCCCTGTGTAAA

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