Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name NAA20P1
Plot displaying the genomic locations of a retrocopy (in chrX) and its respective parental gene (in chr20). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chrX:132907279-132907533  UCSC
Coordinates (T2T) chrX:131231984-131232238  UCSC
Coordinates (hg19) chrX:132041307-132041561  UCSC
Strand -
Parental Sequence NM_181528.3
Parental seq. overlap 214 bp
Parental seq. overlap (%) 22.8%
Genomic Region Intragenic (HS6ST2)
Retrocopy Summary NAA20P1, located on chrX:132907279-132907533, is a retrocopy of the parental gene NAA20. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name NAA20
Full Name N-alpha-acetyltransferase 20, NatB catalytic subunit
Also known as MRT73|NAT3|NAT3P|NAT5|NAT5P|dJ1002M8.1
Coordinate chr20:20017290-20033655
Strand +
Gene summary NAT5 is a component of N-acetyltransferase complex B (NatB). Human NatB performs cotranslational N(alpha)-terminal acetylation of methionine residues when they are followed by asparagine (Starheim et al., 2008 [PubMed 18570629]).[supplied by OMIM, Apr 2009]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes NAA20P1
Bonobo Pan paniscus NAA20P2
Gorilla Gorilla gorilla NAA20P2
Orangutan Pongo abelii NAA20P2
Gibbon Nomascus leucogenys NAA20P1
Green monkey Chlorocebus sabaeus NAA20P1
Crab-eating macaque Macaca fascicularis NAA20P1
Rhesus Macaca mulatta NAA20P1
Baboon Papio anubis NAA20P1
Cat Felis catus NAA20P2
Greater horseshoe bat Rhinolophus ferrumequinum NAA20P1
Golden snub-nosed monkey Rhinopithecus roxellana Without Homology
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>NAA20P1
TTCAACAGCATTAACTTGGAGACACTTACAGAAACTTACAAGATTCCTTTTTACTTACAATATCTTGCCAGAGTATTTTATCATTGCAGAGGCATCTAGTGGAAAGTTAATGGATTGTATTGTGGGTAAAGCAGAAGGTTCAGTAGCTAGGGAAGAATGGCACCGTTATGCCACAGCTCTTTCTGTTGCCCAAAATTTCCATATCTTGGTTTGGCTGTTAAACTCATAGAGTTGTTGGAGGAAATTTCAGAAa
>NM_181528.3
AGCAGTACCCCGTCTCGCTCGGTTCCGCGGCGGCCACGCTCCGGGAGACTTCCGGCAGGGCGGGCGCGGGGTCTTGGCGAACGGTCTTCGGAAGCGGCGGCGGCGCGATGACCACGCTACGGGCCTTTACCTGCGACGACCTGTTCCGCTTCAACAACATTAACTTGGATCCACTTACAGAAACTTATGGGATTCCTTTCTACCTACAATACCTCGCCCACTGGCCAGAGTATTTCATTGTTGCAGAGGCACCTGGTGGAGAATTAATGGGTTATATTATGGGTAAAGCAGAAGGCTCAGTAGCTAGGGAAGAATGGCACGGGCACGTCACAGCTCTGTCTGTTGCCCCAGAATTTCGACGCCTTGGTTTGGCTGCTAAACTTATGGAGTTACTAGAGGAGATTTCAGAAAGATATGAGGAAAGCACTTTCCAGGGATACTGAGAAGAAATCCATCATACCATTACCTCATCCTGTGAGGCCTGAAGACATTGAATAACCCTGGGCAGTGGTTCTTAGGCAGATACTCTAGATGCTTTATGGACAATATTATTTTCATTGGATGATTCTGGAGCTCTATTAGGAGAAAAGTAATCATTTTAGGTCTTAAAGACTTCAAGAAAATACAGGTTATCAATTTATTTTAAATCTCATTGTTTCCAGTTAGCAATATCATACCTATTAAAGCTGTTCATTGTAACAAAATTCAATCAAAAAGGCAGCTAGGTCAGAAGGAAACATACCACTCTCATGGTTCATAGTATTCACTGTATGTATGCTAGGGAAAAGACTTGCTCCAGTCTCCTCCTCAGTTCTGTGCCTGAGAACCACTGCTGCATATATTTGTTTTTAAATTTTGTATTGAACTGTTAATTGAAGCTTTAAAAGCATATATGAAATGTATAAATCTAAGATGTATAATACATTATTGACTCTATGAA

Publications

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