| Retrocopy Name | PTP4A1P5 |
|
| Species | Homo sapiens | |
| Coordinates (hg38) | chrX:27427763-27428234 UCSC | |
| Coordinates (T2T) | chrX:27018021-27018492 UCSC | |
| Coordinates (hg19) | chrX:27445880-27446351 UCSC | |
| Strand | - | |
| Parental Sequence | NM_001385259.1 | |
| Parental seq. overlap | 390 bp | |
| Parental seq. overlap (%) | 8.8% | |
| Genomic Region |
Intergenic |
|
| Retrocopy Summary | PTP4A1P5, located on chrX:27427763-27428234, is a retrocopy of the parental gene PTP4A1. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes. |
| Gene Name | PTP4A1 |
| Full Name | protein tyrosine phosphatase 4A1 |
| Also known as | HH72|PRL-1|PRL1|PTP(CAAX1)|PTPCAAX1 |
| Coordinate | chr6:63516440-63583588 |
| Strand | + |
| Gene summary | This gene encodes a member of a small class of prenylated protein tyrosine phosphatases (PTPs), which contain a PTP domain and a characteristic C-terminal prenylation motif. The encoded protein is a cell signaling molecule that plays regulatory roles in a variety of cellular processes, including cell proliferation and migration. The protein may also be involved in cancer development and metastasis. This tyrosine phosphatase is a nuclear protein, but may associate with plasma membrane by means of its prenylation motif. Pseudogenes related to this gene are located on chromosomes 1, 2, 5, 7, 11 and X. [provided by RefSeq, Jun 2013] |
| Species | Scientific Name | Retrocopy | |
 |
Chimpanzee | Pan troglodytes | PTP4A1P6 |
 |
Bonobo | Pan paniscus | PTP4A1P6 |
 |
Gorilla | Gorilla gorilla | PTP4A1P6 |
 |
Orangutan | Pongo abelii | PTP4A1P5 |
 |
Gibbon | Nomascus leucogenys | PTP4A1P6 |
 |
Green monkey | Chlorocebus sabaeus | PTP4A1P7 |
 |
Crab-eating macaque | Macaca fascicularis | PTP4A1P8 |
 |
Rhesus | Macaca mulatta | PTP4A1P8 |
 |
Baboon | Papio anubis | PTP4A1P6 |
 |
Golden snub-nosed monkey | Rhinopithecus roxellana | PTP4A1P2 |
 |
Mouse lemur | Microcebus murinus | PTP4A1P11 |
 |
Pig | Sus scrofa | PTP4A1P3 |
 |
Dolphin | Tursiops truncatus | PTP4A1P7 |
 |
Horse | Equus caballus | PTP4A1P6 |
 |
Dog | Canis familiaris | PTP4A1P5 |
 |
Velvety free-tailed bat | Molossus molossus | PTP4A1P1 |
 |
Greater horseshoe bat | Rhinolophus ferrumequinum | PTP4A1P1 |
 |
Egyptian rousette | Rousettus aegyptiacus | PTP4A1P4 |
 |
Marmoset | Callithrix jacchus | Without Homology |
 |
Mouse | Mus musculus | Without Homology |
 |
Rat | Rattus norvegicus | Without Homology |
 |
Chinese hamster | Cricetulus griseus | Without Homology |
 |
Rabbit | Oryctolagus cuniculus | Without Homology |
 |
Cow | Bos taurus | Without Homology |
 |
Sheep | Ovis aries | Without Homology |
 |
Panda | Ailuropoda melanoleuca | Without Homology |
 |
Cat | Felis catus | Without Homology |
 |
Pale spear-nosed bat | Phyllostomus discolor | Without Homology |
 |
Greater mouse-eared bat | Myotis myotis | Without Homology |
 |
Kuhl's pipistrelle | Pipistrellus kuhlii | Without Homology |
 |
Sloth | Choloepus didactylus | Without Homology |
 |
Tasmanian Devil | Sarcophilus harrisii | Without Homology |
 |
Opossum | Monodelphis domestica | Without Homology |
 |
Platypus | Ornithorhynchus anatinus | Without Homology |
 |
Chicken | Gallus gallus | Without Homology |
 |
Turkey | Meleagris gallopavo | Without Homology |
 |
Zebra Finch | Taeniopygia guttata | Without Homology |
 |
Budgerigar | Melopsittacus undulatus | Without Homology |
 |
Painted Turtle | Chrysemys picta | Without Homology |
 |
Lizard | Anolis Carolinensis | Without Homology |
 |
Frog | Xenopus tropicalis | Without Homology |
 |
Zebrafish | Danio rerio | Without Homology |
 |
Drosophila | Drosophila melanogaster | Without Homology |
| >PTP4A1P5 |
| AACATGGCTAGAATGAACCTCCCTGCTTCTGTGGACATTGCATACAAAAATGTGAGATTTCTTATTACACACAACCCAACCAATACCTACTTTAATAGATTCTTACAGGAACTTAAGCAGGATGGAGTTACCACCATAGTAAGAGTATGAAAAGCAACTTACAACATTGCTCTTTTAGAGAAGGGAAGCATCCAGGTTCCGGACTGGCCTTTTGATGATGGTACAGCACCATCCAGCCAGATAATTGATAACTGGTTAAAACTTATGAAAAATAAATTTCATGAAGATCCTGGTTGTTGTATTGCAATTCACTGTGTTGTAGGTTTTGGGTGAGCTCCAGTTGCTAGTTGCCCTAGCTTTAATTGAAGGTGGAATGAAATATGAAAATGTAGTACAGTTCATCAGATAAAAGTGACATGGAACTTTTAACAGCAAACAACTTTTGTATTTGGAGAAATATTGTCTTAAAATA |
| >NM_001385259.1 |
| atcatttagatctggatctcctgggagacaccacccctgacttcactgtctaaaCAATTCTGTGGTGTTCTTGGTCACACATTTATGGAGTTTCTGAAGGGCAGTGGAGATTACTGCCAGGCACAGCACGACCTCTATGCAGACAAGTGAACTGTAGAAACTGATTACTGCTCCACCAAGAAGCCCCCATAAGAGTGGTTATCCTGGACACAGAAGTGTTGAATTGAAATCCACAGAGCATTTTACAAGAGTTCTGACCTGGATGGGGTAAACCTCAGTGCACTTCTTTTCTGTTGGCCTCAGTATTACTGGATTGAAGAATTGCTGCTTCTTGTTAGGAGGTTCATTTCACTTATCATTACTTACAACTTCATACTCAAAGCACTGAGAATTTCAAGTGGAGTATATTGAAGTAGACTTCAGTTTCTTTGCATCATTTCTGTATTCAATTTTTTTAATTATTTCATAACCCTATTGAGTGTTTTTTAACTAAATTAACATGGCTCGAATGAACCGCCCAGCTCCTGTGGAAGTCACATACAAGAACATGAGATTTCTTATTACACACAATCCAACCAATGCGACCTTAAACAAATTTATAGAGGAACTTAAGAAGTATGGAGTTACCACAATAGTAAGAGTATGTGAAGCAACTTATGACACTACTCTTGTGGAGAAAGAAGGTATCCATGTTCTTGATTGGCCTTTTGATGATGGTGCACCACCATCCAACCAGATTGTTGATGACTGGTTAAGTCTTGTGAAAATTAAGTTTCGTGAAGAACCTGGTTGTTGTATTGCTGTTCATTGCGTTGCAGGCCTTGGGAGAGCTCCAGTACTTGTTGCCCTAGCATTAATTGAAGGTGGAATGAAATACGAAGATGCAGTACAATTCATAAGACAAAAGCGGCGTGGAGCTTTTAACAGCAAGCAACTTCTGTATTTGGAGAAGTATCGTCCTAAAATGCGGCTGCGTTTCAAAGATTCCAACGGTCATAGAAACAACTGTTGCATTCAATAAAATTGGGGTGCCTAATGCTACTGGAAGTGGAACTTGAGATAGGGCCTAATTTGTTATACATATTAGCCAACATGTTGGCTTAGTAAGTCTAATGAAGCTTCCATAGGAGTATTGAAAGGCAGTTTTACCAGGCCTCAAGCTAGACAGATTTGGCAACCTCTGTATTTGGGTTACAGTCAACCTATTTGGATACTTGGCAAAAGATTCTTGCTGTCAGCATATAAAATGTGCTTGTCATTTGTATCAATTGACCTTTCCCCAAATCATGCAGTATTGAGTTATGACTTGTTAAATCTATTCCCATGCCAGAATCTTATCAATACATAAGAAATTTAGGAAGATTAGGTGCCAAAATACCCAGCACAATACTTGTATATTTTTAGTACCATACAGAAGTAAAATCCCAGGAACTATGAACACTAGACCTTATGTGGTTTATTCCTTCAATCATTTCAAACATTGAAAGTAGGGCCTACATGGTTATTTGCCTGCTCACTTTATGTTTACATCTCCCACATTCATACCAATATACGTCAGGTTTGCTTAACCATTGATTTTTTTTTTTTTTTACCAAGTCTTACAGTGATTATTTTACGTGTTTCCATGTATCTCACTTTGTGCTGTATTAAAAAAACCTCCATTTTGAAAATCTACGTTGTACAGAAGCACATGTCTTTAATGTCTTCAGACAAAAAAGCCTTACATTAATTTAATGTTTGCACTCTGAGGTGCAACTTAACAGGGAGGGCCTGAGAAAAGAATGGGAGGGGGCTATTAATTATTTTTAGCAAAATGTTGCCTTTGTCTTGTGCAAACATGTAGAATATGCTCTTTAATTTAGTAAAATATTTTTTTAAAAGGTAGAGATGCTTTGTTATTGTAATCATAAACTTCCTGAAATTCTTGTAATTTTTTTCCCATACTTATCAGAAGTGTGTTTACCAACTTATTTTTGTTTGAAAGTGTGATTTTTTTTTTCCTTCCCAACCTCTCTTGCAAAAAAAGAAATGGGTTTCTGCTAATGAATTGAGCAGACATCTAATATTTTATATGCCTTTTGAGCTGTGTAACTTAATATTTGGATACTTGACAATTTGTTTTATTATGTAATTGATAAAATGGTGATGTGTATTAATGTTAGTTCAACCATATATTTATACTGTCTGGGGATGTGTGGTTATAGTTCTGTGGGAGAAATAATTTTGTCAGTGTTCACCAGCTTGTAAAAACTTAGTGCGAGAGCTGAAACATCTAAATAAATAATGACATGCATTTATCATCATTGAGATTGGTTTGCTTAAAATTAACTTATTTTGTAGAAGACAAAATGAATTGCACTTCACTTAATGTGTGTCCTCATCTTTTTACAAATAAATGAAGGATTATAAATGATGTCAGCATTTTAGTAAACTTTTAGACAAAATTTGTTAGGGTCATTCATGAAAACTTTAATACTAAAAGCACTTTCCATTATATACTTTTTAAAGGTCTAGATAATTTTGAACCAATTTATTATTGTGTACTGAGGAGAAATAATGTATAGTAGAGgacagccttggtttgtaaagctcagttccactagttcatggttttgtgcaacttctgagcctcagttttctcctttgcaaattaataattacatacctTTATAGATTTTGAAATTAATTTAAATATTAGTATTTGGTACATGAAGGCTTAATGTTAAGTTTCCTTTAATGATCCACAATAATCCCTTTGATCACGTTAATCTAAATCTAGATGTCTTTGTCTAATTTTTTTTGAATAGCAGTTATAAATGTAAAGGACTCAAAGTTTAAGTAAAAAGTGATACTCCACCTTGTGTTTCAAAGAATTTAGTTCCACCTCTTCATACCAGTTTAACACTTAATATATTTCATTGGATTTTAGACAGGGCAAAAGGAAGAACAGGGGCCTCTGGAGGCCCTTGGTTATTTAAATCTTGGATTATTTGTGATAGTAATCACAAATTTTTGGCTAATTTTTAACCTGAGGTTTTGTTTTTTTTTTAAAGGAAATGCAGCCTAGTCTTGAGAACATAATTTTATATAATCAATTACTAAATGTTAAACTATTACCACACAGCCCATAAAACAGCATTTGCGTTTATTGAGAGAGAGGATGTGCCATCATGATTAATGAAAACTATCTTTTGAGTTTGAAAAGAAATTAATTTGCAGTGTTTGGATTGTATATATGGTGCTAAAAATAAATTAATTTACTTTATAAACCTTATCTGTACATTATACGATGTGATGAAATTTGCTTTTTATCCAAATATTTTGTATCTTGTAAATATGGCTAATTATAGGAATGCCTATAATACATCTTAGATTCCTTATATCTAATAAGAGTTCAAAGAGTTATGAGTTGAAGTCTTGAATGCAGGAAACTATCTGATAGTGTTCTAAAATTTGGTTACTTGGGTTTGGATACCCTTAGTGGGATGATGTAAATAGAGGCTAGCTACCTAGGCTTGTCTATAGCAACCATAATGTTGATGTAAGTAATGCGGTTACTGAATCATAAGAAAATGCCATCTCTTTTTAGTTGAAGGAAAACTCTGGAAGTAGGTGCCATTGGTCATTCTGCAGTGCACTGCAACCATTGTTTCCCCTAGTGCCCTCTTTTCCCTAGGGCATTGCTCTCCTATTCCCACGCCTTAACACAGCTCTATACCTAGAAGCAGCCAGCCCAGGCATGCAGTCACATTTAATCACATCCCCCTTCTAGAGTGCTTCAAAATGATGTAGTCCCTCAACTTGGCTAAAGAATCTCAATCTCTTGAAATTTATTTTTTTAATGTCATATTCATCTGGTAAATATCTACTGTTTGCCAGGCATTTAAGAATATGGCAAAGAACATAAAAGATGGTGTCACCAGATTTTGGTCACCAATGAGTACCCGACCCGTTGCCATGATTAAGAGAGAATGCTTTCTATTGGAGTTTCAGGAAATATAATTTGAGAATACTTTAAAGGGAAGTGGAAGTATAAGTGAATGATATTTTTCTTTTACATGTAAACAATGAAGTTATTTCAAAGTTAAGTTTTAAACAAAATACATGAAGTAGTGTCTGCCATACATGTTAATATTCTACATTCTTGCTTCCTTAAATTAATATGTTTGTGTGTATATATGTGCCTCACACCTGAATTGAAAATTAAAGACTGGTTTAAAAGTGGTTTAAAAGTGACATTTAATGTTTCTCCATTACGTTTGGGGTAACCAGCCTAAGTGGAATCTTGGAAGGAAAGTAAGGGAAAAACTTGTATTTGCCTTCAATGAATTAAACCAGTGATATGTGTTAACGTATGAATGAAAGGATTGATGGTGATTTTATAATTATATATATTGCCGCAGTAACCAGTTAATAAATTGATAGCTACCATTTA |
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