| Retrocopy Name | Actc1P2 |
|
| Species | Rattus norvegicus | |
| Coordinates | chr10:109519676-109520632 UCSC | |
| Strand | - | |
| Parental Sequence | NM_019183.1 | |
| Parental seq. overlap | 561 bp | |
| Parental seq. overlap (%) | 32.2% | |
| Genomic Region |
Intragenic (Actg1) |
|
| Retrocopy Summary | Actc1P2, located on chr10:109519676-109520632, is a retrocopy of the parental gene Actc1. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes. |
| Gene Name | Actc1 |
| Full Name | actin, alpha, cardiac muscle 1 |
| Also known as | - |
| Coordinate | chr3:105507403-105512939 |
| Strand | - |
| Gene summary | Predicted to enable ATP binding activity; microfilament motor activity; and myosin binding activity. Involved in cardiac muscle contraction; response to ethanol; and response to xenobiotic stimulus. Predicted to be located in several cellular components, including I band; filopodium; and lamellipodium. Predicted to be part of dynactin complex. Predicted to be active in actin filament; glutamatergic synapse; and sarcomere. Biomarker of hypertension. Human ortholog(s) of this gene implicated in atrial heart septal defect 5; dilated cardiomyopathy; dilated cardiomyopathy 1R; and hypertrophic cardiomyopathy 11. Orthologous to human ACTC1 (actin alpha cardiac muscle 1). [provided by Alliance of Genome Resources, Apr 2022] |
| >Actc1P2 |
| AGGGTGTCATGGTGGGCATGGGCCAGAAAGACTCGTACGTGGGTGATGAGGCCCAGAGCAAGAGGGGTATTCTGACCCTGAAGTACCCTATTGAGCACGGCATTGTCACCAACTGGGACGACATGGAGAAGATCTGGCACCACACCTTCTACAACGAGCTGCGTGTGGCCCCTGAGGAGCACCCGGTGCTTCTGACCGAGGCCCCCCTGAACCCCAAAGCTAACAGAGAGAAGATGACGCAGGTATGCTAGAGCCCGGGCCTCCCCTACCTTGGAGTGTGACGAGTCATTTTCTGTTCTGCCTCATTTCCTGACATTCAAGCATTTCTTTGGTGTTTCCAGGGTTCTGTTCCTCCTCTCCTGGCATTTCCTCCCTGAAGCCTCCAGGTtTTTCTTCACACATCACATTTGTGGCATGCAGCATGTAGAGTGAGGGTGTGGGTGGCTCTGGGTCCTTGCTACTCACTTACTGAGGTGTTCTTTGTCTCTCTGCAGATAATGTTTGAAACCTTCAATACCCCAGCCATGTACGTGGCCATTCAGGCGGTGCTCTCCTTGTATGCATCTGGGCGTACCACTGGCATTGTCATGGACTCTGGTGACGGGGTCACACACACAGTGCCCATCTATGAGGGCTACGCCCTTCCCCACGCCATCTTGCGTCTGGACCTGGCTGGCCGGGACCTGACAGACTACCTCATGAAGATCCTGACTGAAAGGGGCTACAGCTTTACCACCACTGCTGAGAGGGAAATTGTTCGTGACATAAAGGAGAAGCTGTGCTATGTTGCCCTGGATTTTGAGCAAGAAATGGCTACTGCTGCATCATCTTCCTCTTTGGAGAAGAGTTATGAGCTGCCTGATGGGCAGGTGATCACCATTGGCAATGAGCGCTTCCGGTGTCCAGAGGCTCTCTTCCAGCCT |
| >NM_019183.1 |
| GACCAAATAAGGCAAGGTGGCAGCTCAGGGGCCCTCCACCCCTGCCCCCGGCTGCTCCAACTGACCCCGTCCATCAGCGCGCTATAAAGCCGCGCTCCAGGCGACTGTCACCTAGTGCCTGCCACCAGCGCCAGCCCAGCTGAACCCAGCCGCCCAAAGCACGCCTACAGATCCCACAGAAGCTGTACCAGGATGTGTGACGACGAGGAGACCACAGCTTTGGTGTGCGACAATGGCTCCGGACTGGTGAAGGCTGGCTTTGCGGGTGATGATGCTCCCAGAGCTGTCTTCCCATCCATCGTGGGTCGCCCACGCCACCAGGGTGTCATGGTAGGTATGGGGCAGAAAGACTCCTATGTAGGTGACGAGGCTCAGAGCAAGCGAGGCATCCTGACTCTGAAGTACCCCATAGAGCACGGCATTATCACCAACTGGGACGACATGGAGAAGATCTGGCACCACACCTTCTACAATGAGCTCCGTGTGGCCCCTGAGGAGCACCCGACCCTGCTCACTGAGGCCCCACTGAACCCCAAGGCCAACCGTGAGAAGATGACACAGATCATGTTTGAGACCTTCAATGTGCCTGCCATGTATGTGGCCATCCAGGCGGTGCTGTCCCTGTACGCTTCTGGGAGAACCACAGGCATTGTTCTGGATTCTGGCGACGGTGTGACTCATAACGTCCCCATCTATGAGGGTTATGCCTTACCCCATGCCATCATGCGTCTGGATCTAGCTGGTCGGGACCTCACTGACTACCTTATGAAGATCCTCACTGAGCGCGGGTACTCCTTTGTCACCACCGCTGAACGTGAAATTGTCCGAGACATCAAAGAAAAACTGTGTTATGTCGCCCTGGATTTTGAGAATGAGATGGCCACCGCTGCATCTTCCTCCTCTCTGGAGAAGAGCTACGAACTTCCCGATGGCCAGGTCATCACCATTGGCAACGAGCGTTTCCGCTGTCCTGAGACTCTCTTCCAGCCCTCTTTCATTGGTATGGAGTCTGCCGGCATTCACGAAACTACTTATAACAGCATCATGAAGTGTGACATCGATATCCGCAAAGACCTGTACGCCAACAATGTCCTGTCTGGAGGCACCACCATGTACCCTGGGATTGCTGATCGTATGCAAAAGGAAATAACTGCACTGGCTCCCAGCACCATGAAGATTAAGATTATTGCTCCCCCTGAGCGTAAATACTCTGTCTGGATTGGGGGCTCCATCCTGGCCTCTCTGTCTACCTTCCAACAAATGTGGATCAGCAAGCAAGAGTACGATGAGGCCGGGCCCTCCATTGTCCACCGCAAGTGCTTCTGAGGCGGCTACCTTACACTCAGGATGACAGTATTGTGCTTGGAATCCTCTGAGGCCCTCTCCCATCTCCCATCAGTCATTGTACAGTTTGTTTACACACGTGCAGTTTGTTTGTGCTTCAAATATTTATTGCTTTATAAATAAACCAGACCAGGACTTGCAACCT |
| PMID - Link | Title |
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