Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name GkP1
Plot displaying the genomic locations of a retrocopy (in chr14) and its respective parental gene (in chrX). Each line represents a retrocopy.
Species Rattus norvegicus
Coordinates chr14:13751879-13752724  UCSC
Strand +
Parental Sequence NM_024381.2
Parental seq. overlap 709 bp
Parental seq. overlap (%) 17.3%
Genomic Region Intergenic
Retrocopy Summary GkP1, located on chr14:13751879-13752724, is a retrocopy of the parental gene Gk. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name Gk
Full Name glycerol kinase
Also known as ASTP|Gyk
Coordinate chrX:54227291-54303897
Strand -
Gene summary Enables histone binding activity. Involved in response to cold; response to ethanol; and response to xenobiotic stimulus. Located in mitochondrion and nucleus. Used to study familial hypercholesterolemia. Human ortholog(s) of this gene implicated in glycerol kinase deficiency. Orthologous to human GK (glycerol kinase). [provided by Alliance of Genome Resources, Apr 2022]

Homology

Species Scientific Name Retrocopy
Human Homo sapiens GK2
Chimpanzee Pan troglodytes GKP3
Bonobo Pan paniscus GKP3
Gorilla Gorilla gorilla GKP2
Orangutan Pongo abelii GKP2
Gibbon Nomascus leucogenys GKP2
Green monkey Chlorocebus sabaeus GKP2
Crab-eating macaque Macaca fascicularis GKP2
Rhesus Macaca mulatta GKP2
Golden snub-nosed monkey Rhinopithecus roxellana GKP1
Marmoset Callithrix jacchus GKP1
Mouse Mus musculus GkP1
Cow Bos taurus GKP2
Horse Equus caballus GKP1
Dog Canis familiaris GKP4
Panda Ailuropoda melanoleuca GKP2
Cat Felis catus GKP1
Greater mouse-eared bat Myotis myotis GKP1
Greater horseshoe bat Rhinolophus ferrumequinum GKP2
Egyptian rousette Rousettus aegyptiacus GKP1
Baboon Papio anubis Without Homology
Mouse lemur Microcebus murinus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>GkP1
CCACTGTACCGATGTAACAAATGCGAGCAGAACGATGCTTTTCAACATCCACTCTTTGGAATGGGATAAAGAACTCTGTAAATTTTTTGAAATTCCAATGAGCATCCTCCCAAATGTACGCAGTTCTTCCGAGATCTACGGCCAGATGACATCCGGGGCTTTGGAAGGCGTGCCAATATCCGGATGTTTGGGGGATCAGTCTGCTGCTTTAGTGGGACAAATGTGCTTCCAGGAAGGTCAAGCCAAAAACACGTACGGAACCGGATGTTTTTTACTATGCAATACAGGCCAGAAATGTGTATTTTCTGAACATGGCCTTCTGACTACAGTGGCTTACAAACTAGGCAAAAATAAGCCAGCTTTTTATGCCTTAGAAGGCTCTGTTGCTATAGCTGGTGCTGTTATTCGCTGGCTAAGAGACAATTTCGAACTTATAACGTCCTCGGGGGAAGTTGAAGATCTTGCAAGAGAGGTAGGCACGGCCTACGGCTGCTACTTTGTCCCAGCCTTTTCTGGGTTGTATGCACCTTACTGGGAACCCAGTGCAAGAGGGATAATCTGTGGTCTCACTCAGTTCACCAACAAATGCCATATTGCCTTTGCTGCATTAGAAGCCGTTTGTTTCCAAACCCGAGAGATTGTGGATGCCATGAACCGCGACTGTGGGATTCCACTCAGTCATTTGCGGGTAGATGGAAGAATGACCAACAACAAGATTCTCATGCAGCTCCAGGCAGATATTCTGCACATTCCGGTAGTTAAATCTGTTATGCCCGAAACCACAGCCCTGGGAGCAGCCATGGCAGCCGGAGCTGCAGAAGGGATAGATGTTTGGAGTATTGAACC
>NM_024381.2
GCCCTCCGCTCTCCCTGCTCCGCCCTCCGCAGCCCTCCACAGTCACCCCGGAGACCAGCCCTGTTAAGCTCTCGGCTCTGAAGCTGACTGATTTCCATGGCAGCCGCGAAGAAAGCAGTTCTGGGGCCATTGGTGGGAGCAGTGGACCAGGGTACCAGCTCGACACGTTTTTTGGTTTTCAATTCAAAAACAGCTGAACTTCTTAGTCATCATCAAGTAGAAATAAAACAGGAATTCCCAAGAGAAGGATGGGTAGAACAAGATCCGAAGGAAATCCTGCAGTCTGTTTATGAATGTATAGAGAAAACATGTGAGAAACTTGGACAGCTCAATATTGATATTTCCAACATCAAAGCTATTGGTGTCAGCAACCAGAGGGAAACCACAGTAGTCTGGGACAAGCTAACTGGAGAGCCGCTCTACAATGCTGTGGTGTGGCTTGACCTAAGAACCCAATCTACTGTTGAGAAACTTAGTAAAAGAATTCCGGGAAATAATAATTTTGTCAAGTCCAAGACAGGCCTTCCACTTAGCACTTACTTCAGTGCAGTGAAACTTCGTTGGCTCCTCGACAATGTGAAAAAGGTCCAAGAGGCTGTCGAAGAAAATAGAGCTCTTTTTGGGACCATTGATTCATGGCTTATTTGGAGTTTGACAGGGGGAATCAATGGCGGTGTTCACTGTACAGATGTAACAAATGCAAGCAGGACGATGCTTTTTAACATTCATTCTTTGGAATGGGATAAAGAGCTCTGCGAATTTTTTGGAATTCCAATGGAAATTCTTCCCAATGTTCGGAGTTCTTCTGAGATCTATGGCCTAATGAAAGCTGGGGCCTTGGAAGGTGTGCCAATATCTGGGTGTTTGGGGGACCAGTCTGCTGCTTTGGTGGGACAAATGTGCTTCCAGGATGGACAGGCCAAAAACACGTATGGAACAGGGTGCTTCTTACTGTGTAACACGGGCCATAAGTGTGTATTTTCTGAACATGGCCTTTTGACAACTGTGGCTTATAAACTTGGCAGAGACAAACCTGTGTATTATGCATTAGAAGGTTCTGTAGCTATAGCTGGTGCTGTAATCCGCTGGTTAAGAGACAACCTTGGAATTATTAAGTCCTCTGAAGAAATTGAAAAACTTGCTAAAGAAGTAGGTACTTCTTATGGCTGCTACTTTGTTCCAGCATTTTCAGGGTTATATGCACCTTATTGGGAGCctagtgcaagaggGATCATCTGTGGACTCACTCAGTTCACCAATAAATGTCATATCGCTTTTGCTGCATTAGAAGCTGTTTGTTTTCAAACCCGAGAGATTTTGGATGCCATGAACCGTGACTGTGGAATCCCACTCAGCCATTTGCAGGTAGATGGAGGAATGACCAGCAATAAAATTCTTATGCAGCTACAAGCAGACATTCTGTATATTCCAGTAGTGAAGCCCTCCATGCCCGAGACAACTGCTCTAGGAGCTGCCATGGCAGCTGGGGCTGCAGAGGGGGTTGGTGTCTGGAGTCTTGAACCTGAGGATTTGTCAGCTGTCACAATGGAGCGGTTCGAACCTCAGATCAATGCTGAAGAAAGTGAAATCCGTTACTCCACCTGGAAGAAAGCTGTGATGAAGTCCATTGGTTGGGTTACAACTCAATCTCCTGAAAGTGGTATCCCATAAATAATACCACCTCATAGAATCCCAAGATGCAAGCCCTTTAACGTGATATGAAAATCTGACTATTCTGTCTCATAATCTAATGATACTATTCATAGACTCTGATTTTTGCCCATAAAGCACTCGCTGCATGATCCTCCAAGCAGACCTATGCCTTGAAACAAAGAAAATGCAGCAGAAAGAATCCTCCAGAAACATTTAATATTTTTTTTTGATATTGACAGTTAAGATTGGGTCAGTGACCTTTGGGACTGACCCCTGCCTCCACTCTCATGATGCCCTATACTATTCCCCTTAAGGTCTAGGATGAATTTGTATCCTGTCCATTGAAATGTGTCATCCAGTATATTCCAGATGCTGCTGGCCTAAACTTGTCTGAGGAAGGGGTTGTTACTCACCTCTTCAAAATGAGTGGATTCCTGCTTGTTTGCTTTTAACAGCTCAGATGTCTTTTCTACATATTAGAAGACCACAACACCACTGGATATTTCAATGGAAACGTCTAAAGCATTATTGGATAATAACTTGCTATTCTTGTTGCTTAGACATTTTCTGTACAGTGTTTGCCAAAATTGAAATTTTTCAGGTGTTTTACACTGTCTCACTAATTGTCATGGCTTCATGGCTTTCTGTCTGGATCTTACAGGGATAGATAGAATACTTTCTTTTTCTGCTTTTTTTTTCATTCCTCCTTTTTATATTTTTACTCTGTATGTATAACATACATACCTATATATTTTATATGCTGAGGGTAGCCCATTTTTAAATTAAGAGCACATTATATTCAGTAAGTTATAAGAGGGCTGGTCTTAAGTGGACTACTATGTATATAAATTTGAGGGGGGCAAGCTGTACACATTTTTGGGCAACGGTTATGCATATTATTTACCAGAAGAAAAATTTTCTTATCATGAATTTGAAATTTAAGTATGTATTCAGTATCAATAAAATAAAATGTACTGTATTGTAATTTCAACTATATTTCTTATATTCTACCATTTAATTATCTCAGCTGGAAGAAAAGTAACTGTGGAATGTAACAGTAAATATTCTTCTCAAAACATGATTCTAATCCAAATAAAATTTTTTCTTTGAATTTATGTTTTCCATATTTGAGCTCCTATTGAGGAATTAATCAAATTCAAAAGCTAAGTAGAAAAATATGTGTGAATAAAGCCAATAATATCTCCCAAATGTTATTACCAATTAATAAGATGTTCTTATTTTCTGGTATGATATAAAATTATCTCTACTTAATGTCATAACTGGCAAAAAAAAAACTATCATTGCAAATGCCTCCCAGTGAAACCAATAACTTCTCAAATATTTAGAATTATTGGTTATAACTCACTAACCTAGTTTCCTAACATCAATTTAAAATTTGATTTATAGTAAAGAAATAAGAAAATGATGCTTCTAATTATTTTGTTTTGTCCTTTTGGAATGGAAAATATTGATATATTAATAGAAAAAGTTTTATTTGGAATTAATGGTAGATTATATTTCTTATTCTGATTGTGCTGCTCCTAATGATTGAATTTGCTGGATTTTTACTGATACAGCTGCCACTTAAGTGACATAAATATAGAAAGGTACTGTGAAATTATTATGGCAGTGACACTTTTAAGCTTAACTATATTTCTACAAAGGCAGATTGAGTTCATTGTAAATAATTGTGTGAATCACTGTTCCAGTAATTTTAAAATAACATTAACTTTTCTACAAAATGGAAGATTTATAAATGTTGGAAATTGTACCCATTGACAATTAATGGTAAATTTACTTAAAATAAATTTACCTCTTATTTCTTATTCGCATTTCTCATTTCCAGATGAAAGTTCAGTAAACAGAGATGTTTCAGCAGACACAAGTCACCTTTTAACACTTGTTCACATGCACCGAGGAGATAATTAGCAGCAGAAGTGGTTTCTGGAATGATAAACACCTTTAACCATTCAGATAGAACAGACTAAACAGTTTCTACCTCAGCATTTTCAGAAAATCCATTGTCGAGGCCCAAGGCCATTATCAGTAGAGTCTCTCTAGCTGAGACCAACATATCTGTAGGCTTCATCTTTCGCCTCACCTCTGTCTACCTGAGTTAGTCAAGGAGGTCTGAACACGACTGCTAACACTATTGCTCTTTCATGGTGATGCCAACATCTCCACATTTTGTTCTCCAATTGATCCATAAAACAAATAGTGCATTAATGCTTCTTCACTGGTATTCttgtttttttgaagcagggtcttgctatgtagtcctgcctgtcctgcaactcactatgtataccaagctggccttgaattcatagagttctgcctgcctctgtttcttccaactgctggaattaaagacatatgccaccatgcccaacGTCAAGAGCGTCAAGTCTTTTTAAAATTTTCTTGTGGAGTATTAAAATTAAGTAGCTTTTA

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