Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name Morf4l1P14
Plot displaying the genomic locations of a retrocopy (in chrX) and its respective parental gene (in chr9). Each line represents a retrocopy.
Species Mus musculus
Coordinates chrX:135634390-135634860  UCSC
Strand -
Parental Sequence NM_001039147.2
Parental seq. overlap 381 bp
Parental seq. overlap (%) 19.2%
Genomic Region Intragenic (Morf4l2)
Retrocopy Summary Morf4l1P14, located on chrX:135634390-135634860, is a retrocopy of the parental gene Morf4l1. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name Morf4l1
Full Name mortality factor 4 like 1
Also known as MORFRG15|MRG15|TEG-189|Tex189|mKIAA4002
Coordinate chr9:89973722-89996873
Strand -
Gene summary Enables chromatin binding activity. Acts upstream of or within cell population proliferation. Predicted to be located in nuclear speck. Predicted to be part of NuA4 histone acetyltransferase complex and Sin3 complex. Is expressed in several structures, including genitourinary system; limb; liver; retina; and spleen. Orthologous to human MORF4L1 (mortality factor 4 like 1). [provided by Alliance of Genome Resources, Apr 2022]

Homology

Species Scientific Name Retrocopy
Human Homo sapiens MORF4L1P8
Gorilla Gorilla gorilla MORF4L1P6
Orangutan Pongo abelii MORF4L1P7
Gibbon Nomascus leucogenys MORF4L1P6
Mouse lemur Microcebus murinus MORF4L1P4
Rat Rattus norvegicus Morf4l1P14
Chinese hamster Cricetulus griseus Morf4l1_1P8
Rabbit Oryctolagus cuniculus MORF4L1P11
Pig Sus scrofa MORF4L1P1
Cow Bos taurus MORF4L1P5
Sheep Ovis aries MORF4L1P5
Dolphin Tursiops truncatus MORF4L1P3
Horse Equus caballus MORF4L1P1
Dog Canis familiaris MORF4L1P4
Panda Ailuropoda melanoleuca MORF4L1P2
Cat Felis catus MORF4L1P4
Pale spear-nosed bat Phyllostomus discolor MORF4L1P10
Velvety free-tailed bat Molossus molossus MORF4L1P4
Sloth Choloepus didactylus MORF4L1P18
Chimpanzee Pan troglodytes Without Homology
Bonobo Pan paniscus Without Homology
Green monkey Chlorocebus sabaeus Without Homology
Crab-eating macaque Macaca fascicularis Without Homology
Rhesus Macaca mulatta Without Homology
Baboon Papio anubis Without Homology
Golden snub-nosed monkey Rhinopithecus roxellana Without Homology
Marmoset Callithrix jacchus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>Morf4l1P14
GTGAAGATCCCTGAAGAATTAAAACCGTGGCTGGTGGAGGACTGGGACTTGGTTacgaggcagaagcagttgttccAGCTCCCTGCTAAAAAGAATGTCGATGCCATTCTTGAGGAGTATGCCAATTGTAAGAAGTCGCAGGGAAATGTTGATAATAAGGAGTACGCAGTTAATGAAGTTGTAGGAGGGATAAAAGAGTATTTCAATGTGATGCTGGGCACTCAGCTGCTGTACAAGTTTGAAAGGCCTCAGTATGCTGAGATTCTGCTGGCTCACCCTGATGCGCCGATGTCGCAGATCTATGGGGCGCCACACCTCCTGAGATTATTCGTGAGAATTGGGGCAATGTTGGCCTATACGCCCCTTGATGAGAAAAGCCTGGCATTATTGCTGGGCTATCTGCATGATTTCCTTAAGTATCTGGCAAAGAATTCTGCCTCTCTGTTTACTGCCAGTGATTACAAAGTGGCT
>NM_001039147.2
ACCAATCCCGGCATGCCTCTGGGCGGCACGGGCGCAGGCTTGTGTGCGTAGCGGTTAGCCGTTGGCTGAGGCGGCGGCTGCGCGGGTCGCGGTGCTGTGAGGTCAGGCGGCGCTGGCAAATCGCGCCCAGGATGTAGAGCTGGCTGTGGCCGACGGCGCGTCTGACGCTGAGTTGGGTGGGGTAGAGAGTAGGGGGCGGTAGTCGGGGGtggtgggagaaggaggaggcggCGAATCACTTATAAATGGCGCCCAAGCAGGACCCTAAGCCGAAATTCCAGGAGGGCGAGCGAGTGCTGTGCTTTCATGGGCCTCTTCTCTATGAAGCAAAGTGTGTAAAGGTTGCCATAAAGGACAAACAAGTGAAATACTTCATCCATTACAGTGGCTGGAATAAAAAAAGTGCTGTGAGGCCCAGGCGCTCTGAAAAATCTTTGAAGACACGTGAGGATATTGTAGCCCTTTTTCCTGTTCCTGAAGGAGCTCCCTCAGTACACCACCCCCTCCTGACCTCTAGTTGGGATGAATGGGTGCCAGAAAGCAGAGTACTCAAATACGTGGACACCAATTTGCAGAAACAGCGAGAACTTCAAAAGGCCAATCAGGAACAATATGCAGAGGGCAAGATGAGAGGGGCTGCTCCGGGGAAGAAGACATCCGGCCTGCAACAGAAAAATGTCGAAGTgaaaacaaaaaagaacaagcaGAAAACACCTGGAAATGGAGATGGTGGCAGTACCAGTGAGACACCTCAGCCTCCTAGGAAGAAGAGAGCCCGGGTAGATCCTACCGTTGAAAATGAAGAAACCTTCATGAACAGAGTTGAAGTTAAAGTGAAGATCCCTGAAGAGCTGAAACCCTGGCTTGTGGATGACTGGGACTTGATCACCAGACAGAAGCAGcttttttATCTTCCTGCCAAGAAGAATGTGGATTCCATTTTGGAGGATTATGCAAATTATAAGAAGTCTCGAGGAAATACAGATAATAAagagtATGCTGTTAATGAGGTGGTGGCAGGCATAAAGGAGTACTTCAATGTCATGTTGGGCACTCAGCTCCTCTACAAGTTTGAGAGACCACAGTACGCTGAAATCCTCGCCGACCACCCGGATGCGCCCATGTCCCAGGTGTACGGAGCGCCACATTTGCTGAGATTATTTGTGCGAATTGGAGCGATGTTGGCCTACACGCCTCTAGATGAGAAAAGCCTTGCTTTATTACTGAACTATCTACATGATTTTCTCAAGTACCTGGCGAAGAATTCTGCAACCTTGTTCAGTGCCAGTGATTATGAAGTGGCCCCTCCTGAGTACCACCGGAAAGCCGTGTGAGGGCGTGCTCGCCCTCTCTCCCTCGTGCTTGGATCTCTGTAAACAGTTTGGTTCTTAGTCCTTCTCTTGTACAAATGATGTACTTTGAAGACCGTTAGTGTATAACAgagttgtttgtttcctctttgattttaaacagagaaaataaaaggagtaactgctccttttttcttccttttttcatttcAAAGTTTCTACCAGTGTATCAGTGACGGACAACAGAGAGACATgctgtagagtgtttgcctagttgACAAAGCTGCTTTTGAATGCTGGTGGTTCTGTTCCTTTGACACTACGCACTTTTATAATATGTGTTAATGCTCTATGACAAATGCTCTGATTCCTAGTGCCAAAGGTTCACTTCAGTGTATATAACTGAACACTCATCCAtctgtgctcttttttttttttttaatggtgcttAAAGAGCCCATCCTTTGCAAGTCATCCATGTCATTCCTTAGGCATCTTATCTTTGCTCAACTGTTAAAGAATGGTGGCTTGTTTTCATGGGTTTTGTATTTGTGTCTAATGCACGTTTTAACATGATAGACGCAATGCATCGTGTAGCTGCAGTTTTATGGAAAAGTCAATCTTGTAGGAGTTGTTTTTCAGATCTTcaataaattttttctttaaatttcaa

Publications

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