Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name SINHCAFP4
Plot displaying the genomic locations of a retrocopy (in chr12) and its respective parental gene (in chr12). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr12:98317605-98320526  UCSC
Coordinates (T2T) chr12:98290881-98293800  UCSC
Coordinates (hg19) chr12:98711383-98714304  UCSC
Strand +
Parental Sequence NM_001135812.2
Parental seq. overlap 2298 bp
Parental seq. overlap (%) 76.4%
Genomic Region Intergenic
Retrocopy Summary SINHCAFP4, located on chr12:98317605-98320526, is a retrocopy of the parental gene SINHCAF. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name SINHCAF
Full Name SIN3-HDAC complex associated factor
Also known as C12orf14|FAM60A|L4|TERA
Coordinate chr12:31280584-31326218
Strand -
Gene summary Involved in negative regulation of cell migration. Part of Sin3 complex. [provided by Alliance of Genome Resources, Apr 2022]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes SINHCAFP2
Bonobo Pan paniscus SINHCAFP2
Gorilla Gorilla gorilla SINHCAFP3
Orangutan Pongo abelii SINHCAFP1
Gibbon Nomascus leucogenys SINHCAFP3
Green monkey Chlorocebus sabaeus FAM60AP3
Crab-eating macaque Macaca fascicularis FAM60AP2
Rhesus Macaca mulatta SINHCAFP2
Baboon Papio anubis SINHCAFP2
Golden snub-nosed monkey Rhinopithecus roxellana SINHCAFP2
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>SINHCAFP4
TTTTCTAGACAAGGCAGTTGAAGAGGGAGGGCTTACAGAGGGACTGGCCTGGCGTGCACTCTGCATCTCCAGGATGTTGTTTCTTATGGAATGGATGCTTTTGGAAGACTATTGCCCAGAAAAAAGATGTTTAGTTTTTCCCAAGCCAAAGATGTACCGAAGTATAGAGGGCTGTTGTGTTTGCAGAGCTAAGTCCTCCAGTTCTTGATTCACTGACAGTAAACGCTATGAAAAGGACTTCCAGAGCTCTTTGGGGCTGCATGAGACATCTGCGATGCCTGTGTTCTGCTTGTGAAAAGATGGAAGACGTTGCCAGCAGGATCAAAAAACCCTGGATTCATGTGGCAGATGCAGGGCTGGACCCAGTCTAAATACTACACTGAAACCAAAGAGAGTGAAAACTGTATCTGGGAACAGGATAAAAAGCAACCAGACCAATAAACTGCAGAAGAAAGGTAAAGATTGCAATGATGATGCTCACAGTACCACCTCAAGTGCCTCCTTGTTACAGCAACTAGTCAGACGATGGCTCAGTTATGGAGATGGCTTCTGGTTCTACCAGAACACCAGGTGTTTTCCTTTTTAGATCTCACAGACTGAAAAAGAAGATACATAGTGGGATTATTTATAAAGGCCATTTTGGGAAAGTCCTCATCAACTCACATCTGTTCAAGCCTTGCCACAGGAATACAAAAGCAACTACTGAGAAATGTAGGGGCAGGGGCCAGAGCCTCTGCCCACATCACTCAGGAGTAGAAACGGGGAACAAAAAACAATTTAAACTTTGAAAAGACCACAAAGCAACTAACTGTCCCACCTATTTTTAACTTGGATACCTGCTACTCTGCCAAAAAACAACTTCTAGAATAGTTTTGAATGGGTTATTTTCCCCCTAGTCTCACAAATTCTGAAGTCGATTTCTAGCTTCACAAAAAAAGAATTGAAAATAATATTTAAGATGCTGGATATTTCACAAGAAAGCCGAATGCTGCTATAAGTCTTTTTTAATACCCTTCTAATGAATGAAACTAGGGGAATTTCAGGGTACAGAGATGGGATTTGTCATATGCTAAACGGTAGGTAGTTTTAGTCTTTCTATATTGAGAAGCAGTGGTTGGGGCATTTTTTAAGGTAGCTGGCTACACTTGTTTTCCCTCACGATAATAATTTGTCATAACTCAGTAACATGGACTTGCCCCTAGAGGTAGTTGTTAATAATTTTGAAATATTAAGGTCTTGCCAAGGTTCCAACAATTCAAACCTGTACTACTGATTATTAAGCAGGACAGACTGTGCTTTCTGTTGCAAATACCTTAAAGGAAAAAGTAATTTCTAAATATACAGAAAGGAAAGATGACTGTATATGTTGCATCCTGTGCTGCCTCTCTTCATATTAATATTTGATAACGATTTCAATTTTTATGAAACTTCTAAAGCAGAATCAATGCTCCTCTTGGGGAAATGACAAGTCTTTAGGATAGCCAAGACCCTATATGAACAGTACCAAAGCATTACCACATAATAGAGAACACATTTTATTAAAAACATTGAACTATCAGAaTTAAACGAACAAACACAAAAGTTAAACTATCGCAAAAATAAAATGTATAGTCTTCAGGATGGCACAAAGCAAATGTTAGTGCTTCTTAGGGCACATTTCTTAGAGGAATTTCCGAGTGTGTAAATAATTGACTTTTGTTTGTGTTACATGACTGATGACTTTCTTGAAAATCTGCACAGGTCAGTTTTAGGTCTGGATTACTTCAGCTGGCTTTTGTGAAGGTTTTGTCTGTGAAGAGTGGGTGTTTGACTTGTTTTAGCCTATTAGGGTTCTTTTCCACTCTATATTTAAAGAAAACTTTACTAGAAGAGGGGTGGTGTTAATGATAAGTGGGTTGGTTTTGGTTTGGCTTCTTTTAGCCAGCTTAGCTTTCTGAACATTGAGATATCCTGAACTTGGGGCTCTTCAATTCTAAAATGCTCATTAAAAGCCTCTCACTTGAACCCAAGCCAAAGTACTCTTACTGCCTCTTTTCTAAATGTTCAGGAAAAAAAAAATCACCAGTTCAGATTTCACAATGAGGAAGAAGCATTTGTCTGCCTTATGGTAACATAACTCAGTGCTTATTTTTTAAACAGGATTTTTAAAATTGGATAGTATAACAATAAGGAGTTAGTCGCCTTTTATAGGTACCCTATAGTTTTATAGTTAATCTAAACATATTTTATATTTCCTCCTTTTGGAAAAAACTACATGCTACAAGCCAGCATATGCACAGACCACACAATGACTTGGGTTGGCTCTCCCACAGTCTTTGAGGTGAATTATGAGAGTCCAGCCATTATTATCCTCCAGAGTTATTCTGAAAAAAATTGTTTGTATATTTTGGCTGTAGTATTGGTGGTAGGATACACTATAGTATGAATCATCTCTGCTTCTGTATTTATTTATTTTTTACTAGCCCTCAGCCACAGTCTTCTTTTTCCCCTTCCACCTCTCTTTGCCTGTAGGATATACTGTATGTAGTCATGCACTTTGTATTAATACATTCAAAATCCACAGGTCTGTTTTGTACTTTTTAAACTATTGGATACTTACGATCACAAATTTCATGAGGATATTGAATACATTTAGTCTTA
>NM_001135812.2
AGAACTGCAGGAGACTATCTTTCTAGACAAGGCAGTTGAGGAGGAGGGAGCGCTTGAGGGGGACTGGCCTGGCGTGCACTCCGCACCTCGGGGACATTATTGCGCGTGGAACGGCTGCTTTTGGAAGACTATTGCCCAGAAGAAAAGATGTTTGGTTTTCACAAGCCAAAGATGTACCGAAGTATAGAGGGCTGCTGTATTTGCAGAGCTAAGTCCTCCAGTTCTCGATTCACTGACAGTAAACGCTATGAAAAGGACTTCCAGAGCTGTTTTGGATTGCATGAGACTCGTTCAGGAGACATCTGCAATGCCTGTGTCCTGCTTGTGAAAAGATGGAAGAAGTTGCCAGCAGGATCAAAAAAAAACTGGAATCATGTGGTAGATGCAAGGGCTGGACCCAGTCTAAAGACTACATTGAAACCAAAGAAAGTGAAAACTCTATCTGGGAACAGGATAAAAAGCAACCAGATCAGTAAACTGCAGAAGGAATTTAAACGTCATAATTCTGATGCTCACAGTACCACCTCAAGTGCCTCCCCAGCTCAATCTCCTTGTTACAGTAACCAGTCAGATGACGGCTCAGATACAGAGATGGCTTCTGGTTCTAACAGAACACCAGTTTTTTCCTTTTTAGATCTCACTTACTGGAAAAGACAGAAGATATGTTGTGGGATCATCTATAAAGGCCGTTTTGGGGAAGTCCTCATTGACACACATCTCTTCAAGCCTTGCTGCAGCAATAAGAAAGCAGCTGCTGAGAAGCCAGAGGAGCAGGGGCCAGAGCCTCTGCCCATCTCCACTCAGGAGTGGTGACTGAGGTTTTTATGTAGAAGGGGAACAAAAAAAAAAATATCTGAATTTTGAAAAACCACAAAGCTACAAACTGACCCTCttttttttttgagacggagttttgctcttgttacccaggctggagtgcagtggcgtgatcttggctcactgcaacttccgtctcccgggttcaagtgattctcctgcctcagcctcccaagtagctgggtttataggtgcccgccaccagacccggctaattttttagttttagtagagacggggtttcaccacgttggccaggctggtcttaaaTGACCCTCTTATTTTTAACTTGGATACCTGCTATTCTGCCAAAAGACAATTTCTAGAGTAGTTTTGAATGGGTTGATTTCCCCCACTCCCACAAACTCTGAAGCCAGTGTCTAGCTTACTAAAAAAAGAGTTGTATATAATATTTAAGATGCTGAGTATTTCATAGGAAAGCTGAATGCTGCTGTAAAGTGCTCTTTAAGTCTTTTTTTTTTTTAATCCCCTTCTAATGAATGAAACTAGGGGAATTTCAGGGGACAGAGATGGGATTTGTTGTATGATAAACTGTATGTAGTTTTTAGTCTTTCTGTTTTGAGAAGCAGTGGTTGGGGCATTTTTAAGATGGCTGGCTACTCTTGTTTTCCCTCATGATAATAAATTTGTCATAACTCAGTAACATGAACTTGCCCCTAGAGGTAGTTGTTAATAATTTTGAAATATTAAGGTCTTGCCAAGCTTCTGATGATTCACACCTGTACTACTGATTATTAAGCAGGACAGACTGAGCTTTCTGTTGCAAATACCTTGGAGGAGAAAGTAATTTCTAAATATACAGAGAGGTAACTTGACTATATATGTTGCATCCTGTGCCTCCCTTCATATTAATATTTGATAAAGATTTTAATTTATGTAAAACTTCTAAAGCAGAATCAAAGCTCCTCTTGGGGAAATGGCAAGTCTTTAGGATAGGCAAGACCCTGTATGAATAGTACCAAAGCATTACCGCATGGTAGAGAACACACTCGATTAAAAATGTTAAGCTATCTGAAAAATAAAATGTGCAAGTCTTCAGGATGGCACAAAACAAAGGTTAATGCTTCTTGGGGCACATTTCTTAGAGGGCTTGCTGAGTGTGTAAATATAATCGACTTTTGTTTGTGTTACATGACTTCTGTGACTTCATTGAAAATCTGCACAATTCAGTTTCAGCTCTGGATTACTTCAGTTGACCTTTGTGAAGGTTTTTATCTGTGTAGAATGGGTGTTTGACTTGTTTTAGCCTATTAAATTTTTATTTTCTTTCACTCTGTATTAAAAGTAAAACTTACTAAAAGAAAAGAGGTTTGTGTTCACATTAAATGGTTTTGGTTTGGCTTCTTTTAGTCAGGCTTTCTGAACATTGAGATATCCTGAACTTAGAGCTCTTCAATCCTAAGATTTTCATGAAAAGCCTCTCACTTGAACCCAAACCAGAGTACTCTTACTGCCTCTTTTCTAAATGTTCAGGAAAAGCATTGCCAGTTCAGTCTTTTCAAAATGAGGGAGAAACATTTGCCTGCCTTGTAATAACAAGACTCAGTGCTTATTTTTTAAACTGCATTTTAAAAATTGGATAGTATAATAACAATAAGGAGTAAGCCACCTTTTATAGGCACCCTGTAGTTTTATAGTTCTTAATCTAAACATTTTATATTTCCTTCTTTTGGAAAAAACCTACATGCTACAAGCCACCATATGCACAGACTATACAGTGAGTTGAGTTGGCTCTCCCACAGTCTTTGAGGTGAATTACAAAAGTCCAGCCATTATCATCCTCCTGAGTTATTTGAAATGATTTTTTTTGTACATTTTGGCTGCAGTATTGGTGGTAGAATATACTATAATATGGATCATCTCtacttctgtatttatttatttattACTAGACCTCAACCACAGTCTTCTTTTTCCCCTTCCACCTCTCTTTGCCTGTAGGATGTACTGTATGTAGTCATGCACTTTGTATTAATATATTAGAAATCTACAGATCTGTTTTGTACTTTTTATACTGTTGGATACTTATAATCAAAACTTTTACTAGGGTATTGAATAAATCTAGTCTTACTAGAAAATAAAA

Publications

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