| Retrocopy Name | RPL12P40 |
|
| Species | Homo sapiens | |
| Coordinates (hg38) | chr18:37672852-37673219 UCSC | |
| Coordinates (T2T) | chr18:37866418-37866785 UCSC | |
| Coordinates (hg19) | chr18:35252815-35253182 UCSC | |
| Strand | + | |
| Parental Sequence | NM_000976.4 | |
| Parental seq. overlap | 313 bp | |
| Parental seq. overlap (%) | 49% | |
| Genomic Region |
Intergenic |
|
| Retrocopy Summary | RPL12P40, located on chr18:37672852-37673219, is a retrocopy of the parental gene RPL12. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes. |
| Gene Name | RPL12 |
| Full Name | ribosomal protein L12 |
| Also known as | L12 |
| Coordinate | chr9:127447674-127451406 |
| Strand | - |
| Gene summary | Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L11P family of ribosomal proteins. It is located in the cytoplasm. The protein binds directly to the 26S rRNA. This gene is co-transcribed with the U65 snoRNA, which is located in its fourth intron. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008] |
| Species | Scientific Name | Retrocopy | |
 |
Chimpanzee | Pan troglodytes | RPL12P39 |
 |
Bonobo | Pan paniscus | RPL12P36 |
 |
Gorilla | Gorilla gorilla | RPL12P36 |
 |
Orangutan | Pongo abelii | RPL12P45 |
 |
Gibbon | Nomascus leucogenys | RPL12P13 |
 |
Green monkey | Chlorocebus sabaeus | RPL12P27 |
 |
Crab-eating macaque | Macaca fascicularis | RPL12P44 |
 |
Rhesus | Macaca mulatta | RPL12P45 |
 |
Baboon | Papio anubis | RPL12P43 |
 |
Golden snub-nosed monkey | Rhinopithecus roxellana | RPL12P48 |
 |
Marmoset | Callithrix jacchus | RPL12P48 |
 |
Mouse lemur | Microcebus murinus | RPL12P18 |
 |
Pig | Sus scrofa | RPL12P7 |
 |
Dolphin | Tursiops truncatus | RPL12P15 |
 |
Horse | Equus caballus | RPL12P6 |
 |
Dog | Canis familiaris | RPL12P9 |
 |
Panda | Ailuropoda melanoleuca | RPL12P47 |
 |
Cat | Felis catus | RPL12P45 |
 |
Velvety free-tailed bat | Molossus molossus | RPL12P16 |
 |
Mouse | Mus musculus | Without Homology |
 |
Rat | Rattus norvegicus | Without Homology |
 |
Chinese hamster | Cricetulus griseus | Without Homology |
 |
Rabbit | Oryctolagus cuniculus | Without Homology |
 |
Cow | Bos taurus | Without Homology |
 |
Sheep | Ovis aries | Without Homology |
 |
Pale spear-nosed bat | Phyllostomus discolor | Without Homology |
 |
Greater mouse-eared bat | Myotis myotis | Without Homology |
 |
Kuhl's pipistrelle | Pipistrellus kuhlii | Without Homology |
 |
Greater horseshoe bat | Rhinolophus ferrumequinum | Without Homology |
 |
Egyptian rousette | Rousettus aegyptiacus | Without Homology |
 |
Sloth | Choloepus didactylus | Without Homology |
 |
Tasmanian Devil | Sarcophilus harrisii | Without Homology |
 |
Opossum | Monodelphis domestica | Without Homology |
 |
Platypus | Ornithorhynchus anatinus | Without Homology |
 |
Chicken | Gallus gallus | Without Homology |
 |
Turkey | Meleagris gallopavo | Without Homology |
 |
Zebra Finch | Taeniopygia guttata | Without Homology |
 |
Budgerigar | Melopsittacus undulatus | Without Homology |
 |
Painted Turtle | Chrysemys picta | Without Homology |
 |
Lizard | Anolis Carolinensis | Without Homology |
 |
Frog | Xenopus tropicalis | Without Homology |
 |
Zebrafish | Danio rerio | Without Homology |
 |
Drosophila | Drosophila melanogaster | Without Homology |
| >RPL12P40 |
| TATTACAGTGGAACTGACCATTCAGAACAGACAGGCCAAATTGAGGTGGTACTTTTTGTCTCTGTCCTGATGATCAAAGTCCCCAAGGAACCAGTCAGAGACAGAAAGAAGCAGAAAAACATTAAGCACAGTGACAGTATCACTTTTGATGACATTGTCAAGATTGCCCAACAGATGCAGCACCAGTCTTTAATTAGAGAACTCTGGAACCATAAAATAGCTTTGGAGTACTGCACAGTTTGTGGGCTGTAATGTTGATGGCCACCACCTTCATGATATCATAGATGACATCAACAGTGATGCAGTGGAATGCCCAGCTAGTTTAGACCTATGAAGGAAAATATTTCCATAAAGGATCATTTGACAAC |
| >NM_000976.4 |
| CCTCTCGGCTTTCGGCTCGGAGGAGGCCAAGGTGCAACTTCCTTCGGTCGTCCCGAATCCGGGTTCATCCGACACCAGCCGCCTCCACCATGCCGCCGAAGTTCGACCCCAACGAGATCAAAGTCGTATACCTGAGGTGCACCGGAGGTGAAGTCGGTGCCACTTCTGCCCTGGCCCCCAAGATCGGCCCCCTGGGTCTGTCTCCAAAAAAAGTTGGTGATGACATTGCCAAGGCAACGGGTGACTGGAAGGGCCTGAGGATTACAGTGAAACTGACCATTCAGAACAGACAGGCCCAGATTGAGGTGGTGCCTTCTGCCTCTGCCCTGATCATCAAAGCCCTCAAGGAACCACCAAGAGACAGAAAGAAACAGAAAAACATTAAACACAGTGGGAATATCACTTTTGATGAGATTGTCAACATTGCTCGACAGATGCGGCACCGATCCTTAGCCAGAGAACTCTCTGGAACCATTAAAGAGATCCTGGGGACTGCCCAGTCAGTGGGCTGTAATGTTGATGGCCGCCATCCTCATGACATCATCGATGACATCAACAGTGGTGCTGTGGAATGCCCAGCCAGTTAAGCACAAAGGAAAACATTTCAATAAAGGATCATTTGACAACTGGTGGA |
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