Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name SMARCE1P6
Plot displaying the genomic locations of a retrocopy (in chr2) and its respective parental gene (in chr17). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr2:26149113-26150768  UCSC
Coordinates (T2T) chr2:26184408-26186063  UCSC
Coordinates (hg19) chr2:26371982-26373637  UCSC
Strand +
Parental Sequence NM_003079.5
Parental seq. overlap 1228 bp
Parental seq. overlap (%) 23.8%
Genomic Region Intergenic
Retrocopy Summary SMARCE1P6, located on chr2:26149113-26150768, is a retrocopy of the parental gene SMARCE1. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name SMARCE1
Full Name SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1
Also known as BAF57|CSS5
Coordinate chr17:40624962-40647818
Strand -
Gene summary The protein encoded by this gene is part of the large ATP-dependent chromatin remodeling complex SWI/SNF, which is required for transcriptional activation of genes normally repressed by chromatin. The encoded protein, either alone or when in the SWI/SNF complex, can bind to 4-way junction DNA, which is thought to mimic the topology of DNA as it enters or exits the nucleosome. The protein contains a DNA-binding HMG domain, but disruption of this domain does not abolish the DNA-binding or nucleosome-displacement activities of the SWI/SNF complex. Unlike most of the SWI/SNF complex proteins, this protein has no yeast counterpart. [provided by RefSeq, Jul 2008]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes SMARCE1P1
Bonobo Pan paniscus SMARCE1P1
Gorilla Gorilla gorilla SMARCE1P1
Orangutan Pongo abelii SMARCE1P1
Gibbon Nomascus leucogenys SMARCE1P5
Golden snub-nosed monkey Rhinopithecus roxellana SMARCE1P6
Marmoset Callithrix jacchus SMARCE1P7
Green monkey Chlorocebus sabaeus Without Homology
Crab-eating macaque Macaca fascicularis Without Homology
Rhesus Macaca mulatta Without Homology
Baboon Papio anubis Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>SMARCE1P6
TAAAGGGAAGTGAAGCCAGGGCTTGGGGCACTTTTTCTGCCCATGAAGTCTCAGATTCATTCTTAAGGAACTGAGAACTTAATCTTCCAAAATGTCAAAAAGACCATCTTATGCCCCAACTCCCACCCCAGCTCCTGCAACACAAATGTCCAGTACACCAGGGTTTGTGGGATACAATCCTTACAGTCATCTCACCTACAACAACTACAGGCTGGGAGGCAACCCAGGCACCAATAGCCGGGTCCCAGCGTCCTTTGGTATTATGATTCCAAAACCCCCAAAGCCACCAGATAAGCCGCTGATGTGCTACATGAGGTACAGCAGAAAGGTCTGGGACCAAGTAAAGGCTTCCAACCCTGACCTAAAGTTGTGGGAGATTGGCAAGCTTATTGATGGCATGTGGGGAGATCTCACTGATGAAGAGAAACAAGAATAAACAAATACAAAGTAGAAAAGATAGAGTACAATGAATCTATGAAGACCTCTAATTCCACACGAACCTTGCTTACATAAATGCTGCAAAAAGTCATGCAGAAGCTGCTTTAGAGGAAGAAAGTGGACAGAGGCAGTCTCGCATGAAGAGAGGAGAACCTGACGTGAGCATTCAGCTTGCTGAAGATCCAGATGATTGTGACGATGGCTGACAATGGCTTTTCAATGGAGCATACGGACACCGCCCGTTTCCAGAGAAATCATGGCCGCATCAGTGAAATCCTTAGTGACAGTGTGGTGCCAGACATTCCGTCCGCTGTCACAACAGCTAGCATGCAGGTCCTCAAGCGACAGGTCCAGTCCTTAATGGTTCATCAGCGAAAACTAGAAGCTGAACTTCTTCAAATAGAGGAACGGCATCAGAAGAAGAAGAGGAAATTCCTGGAAAGCACGGCTTCATTTAACAGTGAACTTAAAAGGTTGTGCGGTCTGAAGGTAGAACTGGATATGGAGAAAACTGTAGCTGAGATTGCACAGGCAGAGAAACAGGGCCGCAAAAGGCAGGAGGAAAGGGAGGAGGCGGCAGTGCAAGCTGAGCCAGTCAGAGCAGCCTCGTTCCTGAGGAAGAGCAAGCGGGCAACAAAGGCGAGGAAAAGAAAGACGACACGAACCTTCCAAGGGAGACAGAGGAGACACACTCTGAAGAAGAGCCAACGGAACAGTGAAGAAGGCATGTCTACTCCTGAGGACAAGGAGAGTGGGTAGGAGGGGTCGACTGTATGGCAGAGAAGGAACCAGTGATAGTAACACTGGCTTGGAGAGTAACAGCCAACAGTGGAAGAGCCACCAACAGATCCCATACCAAGAGACGAGAAAAAAGAATAAATGTGGCCTTGTTTTATGTGTTCTAAATACTTTT
>NM_003079.5
CAAAGGGAAGCGAAGCCGGAGCTGCGGGCGCTTTTTCTGCCCGCGGTGTCTCAGATTCATTCTTAAGGAACTGAGAACTTAATCTTCCAAAATGTCAAAAAGACCATCTTATGCCCCACCTCCCACCCCAGCTCCTGCAACACAAATGCCCAGCACACCAGGGTTTGTGGGATACAATCCATACAGTCATCTCGCCTACAACAACTACAGGCTGGGAGGGAACCCGGGCACCAACAGCCGGGTCACGGCATCCTCTGGTATCACGATTCCAAAACCCCCAAAGCCACCAGATAAGCCGCTGATGCCCTACATGAGGTACAGCAGAAAGGTCTGGGACCAAGTAAAGGCTTCCAACCCTGACCTAAAGTTGTGGGAGATTGGCAAGATTATTGGTGGCATGTGGCGAGATCTCACTGATGAAGAAAAACAAGAATATTTAAACGAATACGAAGCAGAAAAGATAGAGTACAATGAATCTATGAAGGCCTATCATAATTCCCCCGCGTACCTTGCTTACATAAATGCAAAAAGTCGTGCAGAAGCTGCTTTAGAGGAAGAAAGTCGACAGAGACAATCTCGCATGGAGAAAGGAGAACCGTACATGAGCATTCAGCCTGCTGAAGATCCAGATGATTATGATGATGGCTTTTCAATGAAGCATACAGCCACCGCCCGTTTCCAGAGAAACCACCGCCTCATCAGTGAAATTCTTAGTGAGAGTGTGGTGCCAGACGTTCGGTCAGTTGTCACAACAGCTAGAATGCAGGTCCTCAAACGGCAGGTCCAGTCCTTAATGGTTCATCAGCGAAAACTAGAAGCTGAACTTCTTCAAATAGAGGAACGACACCAGGAGAAGAAGAGGAAATTCCTGGAAAGCACAGATTCATTTAACAATGAACTTAAAAGGTTGTGCGGTCTGAAAGTAGAAGTGGATATGGAGAAAATTGCAGCTGAGATTGCACAGGCAGAGGAACAGGCCCGCAAAAGGCAGGAGGAAAGGGAGAAGGAGGCCGCAGAGCAAGCTGAGCGCAGTCAGAGCAGCATCGTTCCTGAGGAAGAACAAGCAGCTAACAAAGGCGAGGAGAAGAAAGACGACGAGAACATTCCGATGGAGACAGAGGAGACACACCTTGAAGAAACAACAGAGAGCCAACAGAATGGTGAAGAAGGCACGTCTACTCCTGAGGACAAGGAGAGTGGGCAGGAGGGGGTCGACAGTATGGCAGAGGAAGGAACCAGTGATAGTAACACTGGCTCGGAGAGCAACAGTGCAACAGTGGAGGAGCCACCAACAGATCCCATACCAGAAGATGAGAAAAAAGAATAAGTGTTGCCTTGTTTTGTGTGTTCTAAATACTTTTTTTAATGAAAAAATGTTTTTTGGTTTTAATGGTGTTACGTGGTTTGTGTATTAATTTTTTTTCTTGTCCATATCACACCACCAAAGGCTTTTGGACCATTTAGCATCATGAGCCTAATGGCTCAGTCAGTCACCTTTCTTAAGTGTTGTGAAGATGGCTCTTTTCTTTGGATCTTGTTTCTAGCCCTCAACTGCTGAAAGCCTCAGAATTTAGATTAATTGAGAAAACACCCACCTCTTTTAGAGAATTATCCTTTGATGCTGCAGAATCTACTCTTACAATGCCTTCCTACAGCTCACTGGGGTGCTTACCAAAGCCATAGCTTTAAACCTTCCCAGTCCCCATCAGTAGCTTCCTGAAAGTCTCCTCTCTTGTTTACTTCTGCAAAGGGTAGCTTCTTAAAAACGTGATCATGTATGAGTATGTATTTGTTCACTTACCCTTTTTTACTTTTAATCAATGTCAGATACCAAGAGTTGTGTTAAGCTGAGTGTAGTGTGTAACTAACTACACTTGGATCTTACTGATCCAGAAATAGTCCCCATAGTTAGAGTAGTTACTTATGAAGTGGTTATTAAAGTGAACACAGCACATATACATTATCTATACTGCTTTTTGTTATGATTAATACTGGGTATGTTCTGGTAAATCCATCCTTATTGTATAGAAAAAAAATTACTTTTTTACCAGGTTTTCCAAAGACAGAATAGATCACAAAGCTCAAGGAATTTAATATTCTTGTAATGGACTAGATAATTCAAACTGATTAGCCCATTCCAGAAGAAAAACAGCTGGGAATTAAGTTAATCCACTTGAAATTGTTTTACAATAATCAGAACATCCAAACCTCAAGGCTCAGGATCCCATAGACCAGAGCCCACCTTTTTGATAAACTTAGTAAAGTCTTGGAGACTAGAAGCAAGATAGTTTGTGACACATAAGCTTCCCAAAAACTAGAATAGATTTTTACTGAATAGTGGTATATCTGATGGTATATGTTTCTTAAAGGTCCAAATGTAATAAAAAAAAAAATGAAAAAAAGGTCTCAGTGTTTTTAATGCACTACATATTTGTATGCAAGACAAGCATCCAGTTTTTTTCTGTAATGCAGTGACAGTGTGGAATGACCACTCAGCCATTATAAATTTGTGTACTCAGGGCCCTTGTCTCACCCAACTATCTCTATAAACTGCTGCAGTAGCTTATTTGTACAAGACACTTGTGAAAATCAGTTTTCTTACATTATAGTCATTGTCACATATGGAAGTTGGTCTTTGATTCCAAAAGTAAAGGGAATATGTTTCTACATTAACAGGAATATGGAGAAATCTGTAACGTTTGAATTATCTTTGAAAGAATGGCTAAATGATAAATGTTAAGTCCTGTGCCTATATGGAGAGGACTCTGTACCAGCATGAGTTAATTTAAGTGGATTCACTGCTATTCAGTTCATAGCACATTAGTGACTAGGAATGTGTGTTCAGCCTCCTGAGAGAGGAGGGGAGGAAGCTTGATACTGGGTGGAAACAACTCTTGACATCTGTTTCCTTGTGTGTCAAAGAACGAATTTGTATCAAATAGATCTGTTTTGAGCTTTGGCCATTATTTGGCTAAGAACTTCAGCCATCTCATCTCAGACAAATTGGACAGCCTCTTTGATACATTTTCTAGTAGTCAAAATGGGGCAGATGTAGTTTAATATGGGTGGAAAACTGCCCCAGCAAGATACCAGGTTATTTACTGTGGTATCGAAAGCTCTAAGAGAATGGAAGTGGTTCTTTTGCCCGGCTGGAAATAGCAGTGGGAAGACAAGTCTATCCAGACCAAGCCTGTCCATACAACACTGGCAATCAGTTGATGAGGGAATTAAGTCAGATGGgagacgtctcaatctgtcgcccaggttggagtgcagtggtggcgatctcagctcactgcaacctccacctcccaggttcaagcaattctctctgcctcagcctctagagcagctgggattacaggctctcgccaccatgcccggttaatttttgtattttttagtagagatggggtttcaccatgttagccaggctgatcttgaactcgtgacctcaggtgatccgcctgcctcagtctcccaaagtgctgggattacaggcgtgagccactgtgcccggccTCAGTTGGGATTTGACAGCTCTGAACCTCAGCAGGGGAAGATTGATGTAAAAATCCACTTGGTCAGAGTGATATATGTAGACTTGATGTTTGAGATGGTTCTCAGTTTAGAGAATGTGGGATATGGTAGAGGTCTTTGTTTTTTTCCCATGTCCCAAAAGGTGCTGGGCAAGTAGCTTGAACTCGAGCCTGTTTTAATTATAAAATAGATCAAACTGCTCTTTCTTGGTGCCCTTACTGCTCCTTGATTTTTAGTGCATTTATTTTGAGTATGAATGCATAAAGTCTGAGGGCCTAAATTTTGTTAATTTTTTTTAACAAATGGGAGAGGGGAATCCTCGATAGTCACCCAAttttcctttttttttgagacagtctgactgttgcccaggctggagtgtaatggcgccatctcggctcactgcaacatccagctcctgggtttcagcaattctcctgcctcagcctcctgagtagctgggattacaggcgcccgccaccacgcccggctaatttttgtatttttagtagagacaggattttgccatgtttgccagcctggtctcgaactcttgacctcctgatccaccctcctctgcctcccaaagtgctgggattacaggcgtgagccaccgcgcccagccCCATAGTCCCCCAATTTTCTAACAGTTTTAAATTCTGTAACTTCTCCTGTCTGTAAACAAGGCTGTCTTTTCAAATGGCTCTCCTACAGGATGTGATAATTATCTATTCTATAAAGCCGAGGTTTGGAGAGGTAAATAGCTATTTCACATTAACACAATAATGTCAATGCCCTATGGAAAAGATAAAATACTTGGACTATATTTTAAAGGGGAATCTGGGGTCATGCATATTGAAGTTTAACTAGATCCCTCCAGATTTTTGGTTTTGATCCTACACATTTAGATACTAGTTTTGGATTTTAGACAGTTGGTGCTGACAGTGTGAAACTCCTATTGCCTGCAGTTAAATTGAAGCTTTGGTTTCTCGTGAACAGGCAGTGAAGCTGGTATTATACTTTAAGTCCTCATTTCAGAAATAGTTTCCCTCCACCCCCAAGCACTACCACACATGGTCTCCCCACCTGGTTTCAGCTAGTGCATTAGTTTTATCTTGTTTTTTACCGCTGGGCAAACCTTGCTGGAACAACAACTGACTTCATGATTTGCACATTTGGAGGGCTTAACGTCTTTGCAAATGAAAAATCCACTGTACAATAACAAGCTCAAAGGAACTCGGAGCCTTTTTAGAAGAAATCGTGCTGAATTATAATGTGGCTTACTGCAATAATGTTTCTTTGATCAGGATGGAAAGGAAAATACTGAGTTTAGCAGAAAACGATGTCTAAATGTATTTGTAATGATACAATTGTTTATAAATGTTTTACTATTAGGTTGAACCATAAGAAATTGCCAGTGTACAATTTCATCTACAAAATGACTGGCTTAACCTAAATTCTGCATTTTATACTCCAAGAATAAGCTCTTCGTGGCAGCTTTCTAAGTGTGAAATGATGGAACTTTCTATTTGCCAGAATGACCTACACTTCTCTAATAGTTTATCTCATATTGTTAGCCAAACGCTGATTAAAATGCAAATTTCAAACTA

Publications

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