| Retrocopy Name | UBQLN1P1 |
|
| Species | Homo sapiens | |
| Coordinates (hg38) | chrX:56564289-56564840 UCSC | |
| Coordinates (T2T) | chrX:55857603-55858154 UCSC | |
| Coordinates (hg19) | chrX:56590722-56591273 UCSC | |
| Strand | + | |
| Parental Sequence | XM_005251948.3 | |
| Parental seq. overlap | 459 bp | |
| Parental seq. overlap (%) | 17.2% | |
| Genomic Region |
Intergenic |
|
| Retrocopy Summary | UBQLN1P1, located on chrX:56564289-56564840, is a retrocopy of the parental gene UBQLN1. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes. |
| Gene Name | UBQLN1 |
| Full Name | ubiquilin 1 |
| Also known as | DA41|DSK2|PLIC-1|UBQN|XDRP1 |
| Coordinate | chr9:83659968-83707979 |
| Strand | - |
| Gene summary | This gene encodes an ubiquitin-like protein (ubiquilin) that shares a high degree of similarity with related products in yeast, rat and frog. Ubiquilins contain an N-terminal ubiquitin-like domain and a C-terminal ubiquitin-associated domain. They physically associate with both proteasomes and ubiquitin ligases, and thus are thought to functionally link the ubiquitination machinery to the proteasome to affect in vivo protein degradation. This ubiquilin has also been shown to modulate accumulation of presenilin proteins, and it is found in lesions associated with Alzheimer's and Parkinson's disease. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
| >UBQLN1P1 |
| ATAGCAACCCGTTTGGGTTGGGGAGCCTGGGAGGACTTGCAGGCCTTAGCAGCCTGGGCTTGAGCTCGACCAACTTCTCTGAGCTCCAGAGCCAGATGCAGCAGCAGCTTATGGCCAGCCCTGAGATGATGATCCAAATAATGGAAAATCCCTTTGTTCAGAGCATGCTTTCGAATCCCGATCTGATGAGGCAGCTCATTATGGCTAATCCACAGATGCAGCAATTGATTCAGAGAAACCCAGAAATCAGTCACCTGCTCAACAACCCAGACATAATGAGGCAGACACTCGAAATTGCCAGGAATCCAGCCATGATGCAAGAGATGATGAGAAATCAAGACCTGGCTCTTAGCAATCTAGAAAGCATCCCAGGTGGCTATAATGCTTTACGGCGCATGTACACTGACATTCAAGAGCCGATGCTGAATGCCGCACAAGAGCAGTTTGGGGGTAATCCATTTGCCTCCGTGGGGAGTAGTTCCTCCTCTGGGGAAGGTACGCAGCCTTCCCGCACAGAAAATCGCGATCCACTACCCAATCCATGGGCACCAC |
| >XM_005251948.3 |
| AAGGGACGTGGGGGAAGGGGCAGGGAGGAGGAAGCGGTGGCTGCTGCGGATGTCGGTGTGAGCGAGCGGCGCCTGAACACACGgcggctgccgagcgcctgacccgggcctgcgccagagcctgcaccGAGCTCCGGGGCCCCACACCCGCTACGGTGGCCCTGCGCCCGTTGCTACTGAGGCGGCGTGCTCTGCATTCTTCGCTGTCCAGGCCTGCCGGCTCTGGTGTCTGCTGGCTCCTCCTTGCTCGCCTGCTCCCTCCTGCTTGCCTGAGTCAccgccgccgccgccgccacagccATGGCCGAGAGTGGTGAAAGCGGCGGTCCTCCGGGCTCCCAGGATAGCGCCGCCGGAGCCGAAGGTGCTGGCGCCCCCGCGGCCGCTGCCTCCGCGGAGCCCAAAATCATGAAAGTCACCGTGAAGACCCCGAAGGAAAAGGAGGAATTCGCCGTGCCCGAGAATAGCTCCGTCCAGCAGTTTAAGGAAGAAATCTCTAAACGTTTTAAATCACATACTGACCAACTTGTGTTGATATTTGCTGGAAAAATTTTGAAAGATCAAGATACCTTGAGTCAGCATGGAATTCATGATGGACTTACTGTTCACCTTGTCATTAAAACACAAAACAGGCCTCAGGATCATTCAGCTCAGCAAACAAATACAGCTGGAAGCAATGTTACTACATCATCAACTCCTAATAGTAACTCTACATCTGGTTCTGCTACTAGCAACCCTTTTGGTTTAGGTGGCCTTGGGGGACTTGCAGGTCTGAGTAGCTTGGGTTTGAATACTACCAACTTCTCTGAACTACAGAGTCAGATGCAGCGACAACTTTTGTCTAACCCTGAAATGATGGTCCAGATCATGGAAAATCCCTTTGTTCAGAGCATGCTCTCAAATCCTGACCTGATGAGACAGTTAATTATGGCCAATCCACAAATGCAGCAGTTGATACAGAGAAATCCAGAAATTAGTCATATGTTGAATAATCCAGATATAATGAGACAAACGTTGGAACTTGCCAGGAATCCAGCAATGATGCAGGAGATGATGAGGAACCAGGACCGAGCTTTGAGCAACCTAGAAAGCATCCCAGGGGGATATAATGCTTTAAGGCGCATGTACACAGATATTCAGGAACCAATGCTGAGTGCTGCACAAGAGCAGTTTGGTGGTAATCCATTTGCTTCCTTGGTGAGCAATACATCCTCTGGTGAAGGTAGTCAACCTTCCCGTACAGAAAATAGAGATCCACTACCCAATCCATGGGCTCCACAGACTTCCCAGAGTTCATCAGCTTCCAGCGGCACTGCCAGCACTGTGGGTGGCACTACTGGTAGTACTGCCAGTGGCACTTCTGGGCAGAGTACTACTGCGCCAAATTTGGTGCCTGGAGTAGGAGCTAGTATGTTCAACACACCAGGAATGCAGAGCTTGTTGCAACAAATAACTGAAAACCCACAACTGATGCAAAACATGTTGTCTGCCCCCTACATGAGAAGCATGATGCAGTCACTAAGCCAGAATCCTGACCTTGCTGCACAGAGACCACAGCTAAGAAAATTGGggatcttaatgctggctgaacactcaggatcacttgggaagctttatagacagtaccgatggttggggcctcatccttagagattttgagataattgcgtccgATAACCCTTTCTCCCTCAAGTTGCCTAGGTACTATCTAGGTTCCATACCACAGGGCTTGAAAAACCACGGAGAATGTGAAATAAACCTTGATAATCTGTAGTTTATATTTGCTGTTCGTTAAAAATGGCTTCTGTAGTGTGTCAGGAATTTGGAAGACTTTATAGTTAATCTCATCCCTTAAATTTTAAAAGCTTTAAGTCAAATGAATGGTTTTTATTTTCTAAATTCTAAAACTATATTGATTCAGGTATCTTTGTGTATAATTCTCAGTAATAACTTATGCCCTCACCAAATTTGTGGAATTGGAAATAACAAATTTTAAGAAGAATTTTTGTGTCTGTGATTCTGTATATTGGAGGTACATTTTATGGAAGATTGATTTATGCATATGAAACTTATCAGACTGAGTTGTTAGTATTAAATGCTTCAATTTACCATAATAAGCCATTTTAAGTGTGTATTTGGCTAATACTGAATGTGCATCTTGCTTTTAAAATTTGACTTTAACAAGCACATGCGTAGCAATTTTGTAATAATCTTACTTTAGTAAAGTGACTTGAGCACTCACATACTATTTTTTTACTCTAAAACAAAATGTTGCTAGTACTAGATTGGCATGTCTTTTATTACAGATAATTTAGAAACTTTTACAATGTTCTTGTTATCTGCAGATTAAAATTTGTGGTTTTTCTATTCTTTTGATTTTTAAATATTTAAAAAGACTCTTGAGTGTAAAAACTTGTGGTATAAGCACTCAGGTAAGTTATAAGAAGTATCTAATAAGATGATTATCTGTGAAAGGATACGTTTAAGATGACATGCTTTTTTAAGATGAAATGAAGTGAATTCCAAAAGATATGTGTGATAACCTCGTTAATATGTTGATGATAAGTATTTGGAACCAATAAAGAAGCAGGTTTGTTGACCTTAAGCCTGTATGAGTTTACTTACTGTGAACTTACTGGTCACTTTGAAATAAATACTGTATGTTCCTGAAA |
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