| Retrocopy Name | Acta1P1 |
|
| Species | Mus musculus | |
| Coordinates | chr5:142890103-142891234 UCSC | |
| Strand | - | |
| Parental Sequence | NM_009606.3 | |
| Parental seq. overlap | 591 bp | |
| Parental seq. overlap (%) | 30.5% | |
| Genomic Region |
Intragenic (Actb) |
|
| Retrocopy Summary | Acta1P1, located on chr5:142890103-142891234, is a retrocopy of the parental gene Acta1. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes. |
| Gene Name | Acta1 |
| Full Name | actin alpha 1, skeletal muscle |
| Also known as | Acta-2|Acts|Actsk-1 |
| Coordinate | chr8:124618497-124621514 |
| Strand | - |
| Gene summary | Predicted to enable ATP binding activity. Involved in skeletal muscle fiber development. Predicted to be located in actin cytoskeleton and sarcomere. Predicted to be part of dynactin complex. Predicted to be active in actin filament; stress fiber; and striated muscle thin filament. Is expressed in several structures, including alimentary system; brain; genitourinary system; heart; and limb. Used to study nemaline myopathy 3. Human ortholog(s) of this gene implicated in congenital fiber-type disproportion and nemaline myopathy 3. Orthologous to human ACTA1 (actin alpha 1, skeletal muscle). [provided by Alliance of Genome Resources, Apr 2022] |
| Species | Scientific Name | Retrocopy | |
 |
Human | Homo sapiens | ACTC1P1 |
 |
Chimpanzee | Pan troglodytes | ACTA1P2 |
 |
Gibbon | Nomascus leucogenys | ACTC1P2 |
 |
Crab-eating macaque | Macaca fascicularis | ACTC1P1 |
 |
Rhesus | Macaca mulatta | ACTA1P1 |
 |
Baboon | Papio anubis | ACTA1P1 |
 |
Golden snub-nosed monkey | Rhinopithecus roxellana | ACTA1P1 |
 |
Marmoset | Callithrix jacchus | ACTA1P1 |
 |
Rat | Rattus norvegicus | Acta1P2 |
 |
Pig | Sus scrofa | ACTC1P1 |
 |
Cow | Bos taurus | ACTC1P2 |
 |
Sheep | Ovis aries | ACTC1P1 |
 |
Dolphin | Tursiops truncatus | ACTA2P1 |
 |
Horse | Equus caballus | ACTC1P2 |
 |
Cat | Felis catus | ACTC1P2 |
 |
Pale spear-nosed bat | Phyllostomus discolor | ACTA1P1 |
 |
Velvety free-tailed bat | Molossus molossus | ACTA1P1 |
 |
Greater mouse-eared bat | Myotis myotis | ACTA1P1 |
 |
Kuhl's pipistrelle | Pipistrellus kuhlii | ACTA1P1 |
 |
Greater horseshoe bat | Rhinolophus ferrumequinum | ACTA1P1 |
 |
Egyptian rousette | Rousettus aegyptiacus | ACTA1P2 |
 |
Bonobo | Pan paniscus | Without Homology |
 |
Gorilla | Gorilla gorilla | Without Homology |
 |
Orangutan | Pongo abelii | Without Homology |
 |
Green monkey | Chlorocebus sabaeus | Without Homology |
 |
Mouse lemur | Microcebus murinus | Without Homology |
 |
Chinese hamster | Cricetulus griseus | Without Homology |
 |
Rabbit | Oryctolagus cuniculus | Without Homology |
 |
Dog | Canis familiaris | Without Homology |
 |
Panda | Ailuropoda melanoleuca | Without Homology |
 |
Sloth | Choloepus didactylus | Without Homology |
 |
Tasmanian Devil | Sarcophilus harrisii | Without Homology |
 |
Opossum | Monodelphis domestica | Without Homology |
 |
Platypus | Ornithorhynchus anatinus | Without Homology |
 |
Chicken | Gallus gallus | Without Homology |
 |
Turkey | Meleagris gallopavo | Without Homology |
 |
Zebra Finch | Taeniopygia guttata | Without Homology |
 |
Budgerigar | Melopsittacus undulatus | Without Homology |
 |
Painted Turtle | Chrysemys picta | Without Homology |
 |
Lizard | Anolis Carolinensis | Without Homology |
 |
Frog | Xenopus tropicalis | Without Homology |
 |
Zebrafish | Danio rerio | Without Homology |
 |
Drosophila | Drosophila melanogaster | Without Homology |
| >Acta1P1 |
| CAGGGTGTGATGGTGGGAATGGGTCAGAAGGACTCCTATGTGGGTGACGAGGCCCAGAGCAAGAGAGGTATCCTGACCCTGAAGTACCCCATTGAACATGGCATTGTTACCAACTGGGACGACATGGAGAAGATCTGGCACCACACCTTCTACAATGAGCTGCGTGTGGCCCCTGAGGAGCACCCTGTGCTGCTCACCGAGGCCCCCCTGAACCCTAAGGCCAACCGTGAAAAGATGACCCAGGTCAGTATCCCGGGTAACCCTTCTCTTTGGCCAGCTTCTCAGCCACGCCCTTTCTCAATTGTCTTTCTTCTGCCGTTCTCCCATAGGACTCCCTTCTATGAGCTGAGTCTCCCTTGGATCTTTGCAGTTTCTGCTCTTTCCCAGACGAGgtctttttttctctcaattGCCTTTCTGACTAGGTGTTTAAACCCTACAGTGCTGTGGGTTTAGGTACTAACAATGGCTCGTGTGACAAAGCTAATGAGGCTGGTGATAAGTGGCCTTGGAGTGTGTATTGAGTAGATGCACAGTAGGTCTAAGTGGAGCCCCTGTCCTGAGACTCCCAGCACACTGAACTTAGCTGTGTTCTTGCACTCCTTGCATGTCTCAGATCTATCCATACAGTTTCACCTGCCCTGAGTGTTTCTTGTGGCTTTCTGAACTTGAcaacattatttatttttctctacagATCATGTTTGAGACCTTCAACACCCCAGCCATGTACGTAGCCATCCAGGCTGTGCTGTCCCTGTATGCCTCTGGTCGTACCACAGGCATTGTGATGGACTCCGGAGACGGGGTCACCCACACTGTGCCCATCTACGAGGGCTATGCTCTCCCTCACGCCATCCTGCGTCTGGACCTGGCTGGCCGGGACCTGACAGACTACCTCATGAAGATCCTGACCGAGCGTGGCTACAGCTTCACCACCACAGCTGAGAGGGAAATCGTGCGTGACATCAAAGAGAAGCTGTGCTATGTTGCTCTAGACTTCGAGCAGGAGATGGCCACTGCCGCATCCTCTTCCTCCCTGGAGAAGAGCTATGAGCTGCCTGACGGCCAGGTCATCACTATTGGCAACGAGCGGTTCCGATGCCCTGAGGCTCTTTTCCAGCCTTCCTTC |
| >NM_009606.3 |
| ACCTGTGCAAGGGGACAGGCGGTCACACGGACGTGAAGCCTCACTTCCTACCCTCGGCACCCAGGGCCAGAGTCAGAGCAGCAgAAACTAGACACCATGTGCGACGAAGACGAGACCACCGCTCTTGTGTGTGACAACGGCTCTGGCCTGGTGAAAGCTGGCTTTGCCGGGGATGATGCCCCCAGGGCTGTGTTCCCATCCATCGTGGGCCGACCCCGTCACCAGGGTGTCATGGTAGGTATGGGTCAGAAGGACTCCTACGTGGGTGATGAGGCCCAGAGCAAGCGAGGTATCCTGACCCTGAAGTACCCCATTGAACATGGCATCATCACCAACTGGGACGACATGGAGAAGATCTGGCACCACACCTTCTACAATGAGCTGCGTGTGGCCCCTGAGGAGCACCCGACTCTGCTCACCGAGGCCCCCCTGAACCCCAAAGCTAACCGGGAGAAGATGACTCAAATCATGTTTGAGACCTTCAACGTGCCTGCCATGTATGTGGCTATCCAGGCGGTGCTGTCCCTCTATGCTTCCGGCCGTACCACCGGCATCGTGTTGGATTCTGGGGACGGTGTCACCCACAACGTGCCCATCTATGAGGGCTATGCCCTGCCACACGCCATCATGCGTCTGGACCTGGCCGGTCGCGACCTCACTGACTACCTGATGAAAATCCTCACTGAGCGTGGCTATTCCTTCGTGACCACAGCTGAACGTGAGATTGTGCGCGACATCAAAGAGAAGCTGTGCTATGTGGCCCTGGACTTCGAGAATGAGATGGCCAccgctgcctcttcctcctccctggaGAAGAGCTATGAGCTGCCCGACGGGCAGGTCATCACCATCGGCAATGAGCGTTTCCGTTGCCCGGAGACGCTCTTCCAGCCTTCCTTTATCGGTATGGAGTCTGCGGGGATCCATGAGACCACCTACAACAGCATCATGAAGTGCGACATCGACATCAGGAAGGACCTGTATGCCAACAACGTCATGTCAGGGGGCACCACCATGTACCCTGGTATCGCTGACCGCATGCAGAAGGAGATCACAGCTCTGGCTCCCAGCACCATGAAGATCAAGATCATCGCCCCCCCTGAGCGCAAGTACTCAGTGTGGATCGGTGGCTCCATCCTGGCCTCGCTGTCCACCTTCCAGCAGATGTGGATCACCAAGCAGGAGTACGACGAGGCTGGCCCCTCCATTGTGCACCGCAAATGCTTCTAGGCGCACTCGCGTCTGCGTTCGCGCTCTCTCTCCTCAGGACGACAATCGACAATCGTGCTGTGGTTGCAGGGTGGCCCCGTCCTCCGCCGTGGCTCCATCGCCGCCACTGCAGCCGGCGCCTGTTTTTGACGTGTACATAGATTGACTCGTTTTAcctcattttgttatttttcaaacAAAGCCCTgtggaaaggaaatggaaaacttGAAGCATTAAAGCCAGCCATTCTGTTTTGCTCCAATAAACTGTG |
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