| Retrocopy Name | ACTC1P1 |
|
| Species | Homo sapiens | |
| Coordinates (hg38) | chr7:5528284-5529404 UCSC | |
| Coordinates (T2T) | chr7:5645807-5646927 UCSC | |
| Coordinates (hg19) | chr7:5567915-5569035 UCSC | |
| Strand | - | |
| Parental Sequence | NM_005159.5 | |
| Parental seq. overlap | 591 bp | |
| Parental seq. overlap (%) | 32.4% | |
| Genomic Region |
Intragenic (ACTB) |
|
| Retrocopy Summary | ACTC1P1, located on chr7:5528284-5529404, is a retrocopy of the parental gene ACTC1. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes. |
| Gene Name | ACTC1 |
| Full Name | actin alpha cardiac muscle 1 |
| Also known as | ACTC|ASD5|CMD1R|CMH11|LVNC4 |
| Coordinate | chr15:34790230-34795549 |
| Strand | - |
| Gene summary | Actins are highly conserved proteins that are involved in various types of cell motility. Polymerization of globular actin (G-actin) leads to a structural filament (F-actin) in the form of a two-stranded helix. Each actin can bind to four others. The protein encoded by this gene belongs to the actin family which is comprised of three main groups of actin isoforms, alpha, beta, and gamma. The alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus. Defects in this gene have been associated with idiopathic dilated cardiomyopathy (IDC) and familial hypertrophic cardiomyopathy (FHC). [provided by RefSeq, Jul 2008] |
| Species | Scientific Name | Retrocopy | |
 |
Chimpanzee | Pan troglodytes | ACTA1P2 |
 |
Gibbon | Nomascus leucogenys | ACTC1P2 |
 |
Crab-eating macaque | Macaca fascicularis | ACTC1P1 |
 |
Rhesus | Macaca mulatta | ACTA1P1 |
 |
Baboon | Papio anubis | ACTA1P1 |
 |
Golden snub-nosed monkey | Rhinopithecus roxellana | ACTA1P1 |
 |
Marmoset | Callithrix jacchus | ACTA1P1 |
 |
Mouse | Mus musculus | Acta1P1 |
 |
Rat | Rattus norvegicus | Acta1P2 |
 |
Pig | Sus scrofa | ACTC1P1 |
 |
Cow | Bos taurus | ACTC1P2 |
 |
Sheep | Ovis aries | ACTC1P1 |
 |
Dolphin | Tursiops truncatus | ACTA2P1 |
 |
Horse | Equus caballus | ACTC1P2 |
 |
Cat | Felis catus | ACTC1P2 |
 |
Pale spear-nosed bat | Phyllostomus discolor | ACTA1P1 |
 |
Velvety free-tailed bat | Molossus molossus | ACTA1P1 |
 |
Greater mouse-eared bat | Myotis myotis | ACTA1P1 |
 |
Kuhl's pipistrelle | Pipistrellus kuhlii | ACTA1P1 |
 |
Greater horseshoe bat | Rhinolophus ferrumequinum | ACTA1P1 |
 |
Egyptian rousette | Rousettus aegyptiacus | ACTA1P2 |
 |
Bonobo | Pan paniscus | Without Homology |
 |
Gorilla | Gorilla gorilla | Without Homology |
 |
Orangutan | Pongo abelii | Without Homology |
 |
Green monkey | Chlorocebus sabaeus | Without Homology |
 |
Mouse lemur | Microcebus murinus | Without Homology |
 |
Chinese hamster | Cricetulus griseus | Without Homology |
 |
Rabbit | Oryctolagus cuniculus | Without Homology |
 |
Dog | Canis familiaris | Without Homology |
 |
Panda | Ailuropoda melanoleuca | Without Homology |
 |
Sloth | Choloepus didactylus | Without Homology |
 |
Tasmanian Devil | Sarcophilus harrisii | Without Homology |
 |
Opossum | Monodelphis domestica | Without Homology |
 |
Platypus | Ornithorhynchus anatinus | Without Homology |
 |
Chicken | Gallus gallus | Without Homology |
 |
Turkey | Meleagris gallopavo | Without Homology |
 |
Zebra Finch | Taeniopygia guttata | Without Homology |
 |
Budgerigar | Melopsittacus undulatus | Without Homology |
 |
Painted Turtle | Chrysemys picta | Without Homology |
 |
Lizard | Anolis Carolinensis | Without Homology |
 |
Frog | Xenopus tropicalis | Without Homology |
 |
Zebrafish | Danio rerio | Without Homology |
 |
Drosophila | Drosophila melanogaster | Without Homology |
| >ACTC1P1 |
| CCAGGGCGTGATGGTGGGCATGGGTCAGAAGGATTCCTATGTGGGCGACGAGGCCCAGAGCAAGAGAGGCATCCTCACCCTGAAGTACCCCATCGAGCACGGCATCGTCACCAACTGGGACGACATGGAGAAAATCTGGCACCACACCTTCTACAATGAGCTGCGTGTGGCTCCCGAGGAGCACCCCGTGCTGCTGACCGAGGCCCCCCTGAACCCCAAGGCCAACCGCGAGAAGATGACCCAGGTGAGTGGCCCGCTACCTCTTCTGGTGGCCGCCTCCCTCCTTCCTGGCCTCCCGGAGCTGCGCCCTTTCTCACTGGTTCTCTCTTCTGCCGTTTTCCGTAGGACTCTCTTCTCTGACCTGAGTCTCCTTTGGAACTCTGCAGGTTCTATTTGCTTTTTCCCAGATGAGCTCTTTTTCTGGTGTTTGTCTCTCTGACTAGGTGTCTAAGACAGTGTTGTGGGTGTAGGTACTAACACTGGCTCGTGTGACAAGGCCATGAGGCTGGTGTAAAGCGGCCTTGGAGTGTGTATTAAGTAGGTGCACAGTAGGTCTGAACAGACTCCCCATCCCAAGACCCCAGCACACTTAGCCGTGTTCTTTGCACTTTCTGCATGTCCCCCGTCTGGCCTGGCTGTCCCCAGTGGCTTCCCCAGTGTGACATGGTGTATCTCTGCCTTACAGATCATGTTTGAGACCTTCAACACCCCAGCCATGTACGTTGCTATCCAGGCTGTGCTATCCCTGTACGCCTCTGGCCGTACCACTGGCATCGTGATGGACTCCGGTGACGGGGTCACCCACACTGTGCCCATCTACGAGGGGTATGCCCTCCCCCATGCCATCCTGCGTCTGGACCTGGCTGGCCGGGACCTGACTGACTACCTCATGAAGATCCTCACCGAGCGCGGCTACAGCTTCACCACCACGGCCGAGCGGGAAATCGTGCGTGACATTAAGGAGAAGCTGTGCTACGTCGCCCTGGACTTCGAGCAAGAGATGGCCACGGCTGCTTCCAGCTCCTCCCTGGAGAAGAGCTACGAGCTGCCTGACGGCCAGGTCATCACCATTGGCAATGAGCGGTTCCGCTGCCCTGAGGCACTCTTCCAGCCTTCCTTCC |
| >NM_005159.5 |
| AGAGCCCGCTGCCGCCGGAGCCGAGCCGACCCGCCCCGCCGACGAACCCCCTGAAGCTGTGCCAAGATGTGTGACGACGAGGAGACCACCGCCCTGGTGTGCGACAACGGCTCTGGGCTGGTGAAGGCCGGCTTTGCGGGCGATGACGCGCCCCGCGCTGTCTTCCCGTCCATCGTGGGCCGCCCGCGGCACCAGGGAGTTATGGTGGGTATGGGTCAGAAGGACTCCTACGTAGGTGATGAAGCCCAGAGCAAGAGAGGCATCCTGACCCTGAAGTATCCCATCGAGCATGGTATCATCACCAACTGGGACGACATGGAGAAGATCTGGCACCACACCTTCTACAATGAGCTCCGTGTGGCTCCCGAGGAGCACCCCACCCTGCTCACAGAGGCCCCGCTGAACCCCAAGGCCAACCGGGAGAAGATGACTCAGATCATGTTTGAGACCTTCAATGTCCCTGCCATGTACGTGGCCATCCAGGCAGTGCTATCCCTGTATGCTTCTGGCCGTACCACAGGCATTGTTCTGGACTCTGGGGATGGTGTAACTCACAATGTCCCCATCTATGAGGGCTACGCTTTGCCCCATGCCATCATGCGTCTGGATCTGGCTGGTCGGGACCTCACTGACTACCTCATGAAGATCCTCACTGAGCGTGGCTACTCCTTTGTCACCACTGCTGAACGTGAAATTGTCCGTGACATTAAAGAGAAGCTGTGCTATGTCGCCCTGGATTTTGAGAATGAGATGGCCACAGCTGCCTCTTCCTCCTCCCTGGAGAAGAGCTATGAACTGCCTGATGGCCAAGTCATCACTATTGGCAATGAGCGCTTCCGCTGTCCTGAGACACTCTTCCAGCCCTCCTTCATTGGTATGGAATCTGCTGGCATCCATGAAACAACTTACAATAGCATCATGAAGTGTGACATTGATATCCGCAAGGACCTGTATGCCAACAATGTCTTATCTGGAGGCACCACTATGTACCCTGGTATTGCTGATCGTATGCAGAAGGAAATCACTGCTCTGGCTCCTAGCACCATGAAGATTAAGATTATTGCTCCCCCTGAGCGTAAATACTCTGTCTGGATTGGGGGCTCCATCCTGGCCTCTCTGTCCACCTTCCAGCAAATGTGGATTAGCAAGCAAGAGTACGATGAGGCAGGCCCATCCATTGTCCACCGCAAATGCTTCTAAGATGCCTTCTCTCTCCATCTACCTTCCAGTCAGGATGACGGTATTATGCTTCTTGGAGTCTTCCAAACCACCTTCCCTCATCTTTCATCAATCATTGTACAGTTTGTTTACACACGTGCAATTTGTTTGTGCTTCTAATATTTATTGCTTTATAAATAAACCAGACCAGGACTTGCAACCTA |
| PMID - Link | Title |
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