Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name ACTC1P2
Plot displaying the genomic locations of a retrocopy (in chr25) and its respective parental gene (in chr10). Each line represents a retrocopy.
Species Bos taurus
Coordinates chr25:38800361-38801479  UCSC
Strand +
Parental Sequence NM_001034585.2
Parental seq. overlap 570 bp
Parental seq. overlap (%) 31.1%
Genomic Region Intragenic (ACTB)
Retrocopy Summary ACTC1P2, located on chr25:38800361-38801479, is a retrocopy of the parental gene ACTC1. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name ACTC1
Full Name actin alpha cardiac muscle 1
Also known as ACTC
Coordinate chr10:30288631-30293908
Strand -
Gene summary N/A

Homology

Species Scientific Name Retrocopy
Human Homo sapiens ACTC1P1
Chimpanzee Pan troglodytes ACTA1P2
Gibbon Nomascus leucogenys ACTC1P2
Crab-eating macaque Macaca fascicularis ACTC1P1
Rhesus Macaca mulatta ACTA1P1
Baboon Papio anubis ACTA1P1
Golden snub-nosed monkey Rhinopithecus roxellana ACTA1P1
Marmoset Callithrix jacchus ACTA1P1
Mouse Mus musculus Acta1P1
Rat Rattus norvegicus Acta1P2
Pig Sus scrofa ACTC1P1
Sheep Ovis aries ACTC1P1
Dolphin Tursiops truncatus ACTA2P1
Horse Equus caballus ACTC1P2
Cat Felis catus ACTC1P2
Pale spear-nosed bat Phyllostomus discolor ACTA1P1
Velvety free-tailed bat Molossus molossus ACTA1P1
Greater mouse-eared bat Myotis myotis ACTA1P1
Kuhl's pipistrelle Pipistrellus kuhlii ACTA1P1
Greater horseshoe bat Rhinolophus ferrumequinum ACTA1P1
Egyptian rousette Rousettus aegyptiacus ACTA1P2
Bonobo Pan paniscus Without Homology
Gorilla Gorilla gorilla Without Homology
Orangutan Pongo abelii Without Homology
Green monkey Chlorocebus sabaeus Without Homology
Mouse lemur Microcebus murinus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>ACTC1P2
GCAGGGCGTAATGGTGGGCATGGGCCAGAAGGACTCGTACGTGGGGGATGAGGCTCAGAGCAAGAGAGGCATCCTGACCCTCAAGTACCCCATTGAGCACGGCATCGTCACCAACTGGGACGACATGGAGAAGATCTGGCACCACACCTTCTACAACGAGCTCCGTGTGGCCCCTGAGGAGCACCCCGTGCTGCTGACCGAGGCCCCCCTGAACCCCAAGGCCAACCGTGAGAAGATGACCCAGGTCAGTGGGCCGTCCTGCCTTGCCTCCGCGCCCCTCCTTTCTTGCCCTTTGCCTCACCCTTTCTCACTTATTCTCTCTTCTGCCATTTTCCTAGGACTTTCTTCTCTGAGCTGAGTCTCCTTTGGAACTTTGCAGGTTCTATTTGCTTTTCCCCAGCTGGAATCTTTTTCTGGTGTTTGCCTTTCTGACTAGGTGTTGCAAGCATAAAGTGCTGTGGGTGTAGGTACTAACCCTGGCTCGTGTGACAAAAGCCAACCGAGGTTGCTGCCAGGCGGCCTCGGAGTGTGTATTCAGTAGGTGCACAGTACGTTCTGAAGTGAACCTCATTCTGGGGCCCCGGCACACTCGGCTGTGTTCCTTGCACTCTTCTGCATGTGCCCAGTCTGGCCCGACTGCCCCTTGTGGTGTCCCAGTATGACGCGGCCCATCTCTTCCTACAGATCATGTTCGAGACCTTCAACACCCCTGCCATGTACGTGGCCATCCAGGCTGTGCTGTCCCTGTATGCCTCTGGCCGCACCACCGGCATCGTGATGGACTCCGGTGACGGGGTCACCCACACGGTGCCCATCTATGAGGGGTACGCCCTTCCCCATGCCATCCTGCGTCTGGACCTGGCTGGCCGGGACCTGACGGACTACCTCATGAAGATCCTCACGGAGCGTGGCTACAGCTTCACCACCACGGCCGAGCGGGAAATCGTCCGTGACATCAAGGAGAAGCTCTGCTACGTGGCCCTGGACTTCGAGCAGGAGATGGCCACCGCGGCCTCCAGCTCCTCCCTGGAGAAGAGCTACGAGCTTCCTGACGGGCAGGTCATCACCATCGGCAATGAGCGGTTCCGCTGCCCTGAGGCTCTCTTCCAGCCTTCCTTC
>NM_001034585.2
AGCGCCTGCAGCCGTCTGAGCCACCGAGCAGATCCCGCCCCGCGGACCACCCCGCTGAAGCTGTGCCAAGATGTGCGACGATGAGGAGACCACCGCCCTGGTGTGCGACAACGGTTCCGGGCTGGTGAAGGCCGGCTTCGCGGGCGACGACGCGCCCCGCGCCGTCTTCCCTTCCATCGTGGGCCGCCCGCGCCACCAGGGAGTCATGGTGGGTATGGGTCAGAAGGATTCCTATGTAGGTGATGAAGCCCAGAGCAAGCGAGGTATCCTGACTCTCAAGTACCCCATTGAACATGGCATCATCACCAACTGGGATGACATGGAGAAGATCTGGCACCATACCTTCTACAATGAGCTCCGTGTAGCCCCAGAGGAGCACCCCACTCTGCTCACCGAGGCTCCACTGAACCCCAAGGCCAACCGTGAGAAGATGACTCAGATCATGTTTGAGACCTTCAATGTCCCCGCCATGTATGTGGCCATCCAGGCAGTGCTGTCCCTGTATGCTTCTGGTCGTACCACAGGCATTGTTCTGGACTCTGGGGATGGTGTGACCCACAACGTCCCCATTTATGAGGGCTATGCCTTGCCCCACGCCATCATGCGTCTGGATCTAGCTGGTCGGGATCTCACAGATTACCTCATGAAGATCCTCACTGAGCGTGGCTACTCCTTTGTCACCACCGCTGAACGTGAGATTGTTCGTGACATTAAAGAGAAGCTGTGCTATGTTGCTCTGGATTTTGAGAATGAAATGGCTACGGCTGCTTCTTCCTCCTCCCTGGAGAAGAGCTATGAACTGCCTGATGGCCAAGTCATCACTATTGGCAATGAGCGCTTCCGCTGCCCTGAGACGCTCTTCCAGCCCTCCTTCATTGGTATGGAATCTGCCGGCATCCATGAAACGACTTACAACAGCATCATGAAATGTGACATTGATATTCGCAAGGACCTGTATGCCAACAATGTCTTATCCGGAGGTACCACCATGTACCCTGGTATTGCTGATCGCATGCAAAAGGAAATCACTGCCCTGGCTCCCAGCACCATGAAAATTAAGATTATTGCTCCCCCTGAGCGTAAGTACTCTGTCTGGATTGGGGGCTCCATCCTGGCCTCCCTGTCCACCTTCCAGCAGATGTGGATCAGCAAGCAAGAGTATGATGAGGCAGGCCCCTCCATCGTCCACCGCAAGTGCTTCTAAGGTGCCTTCTCTCTTAGTCTACATTACATTCAGGATGATGGTATGATGCTTTTTGGAGTCTTCTGAACCACCCTCCCTCATCTCTCATCAATCATTGTACAGTTTGTTTACACACGTGCAATTTATTTGTGCTTCTAATATTTATTGCTTTATAAATAAACCAGATCAGGACTTGCAACCTACAAAA

Publications

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