| Retrocopy Name | RHOCP1 |
|
| Species | Homo sapiens | |
| Coordinates (hg38) | chr2:20447464-20447811 UCSC | |
| Coordinates (T2T) | chr2:20481107-20481454 UCSC | |
| Coordinates (hg19) | chr2:20647225-20647572 UCSC | |
| Strand | + | |
| Parental Sequence | NM_001042678.2 | |
| Parental seq. overlap | 292 bp | |
| Parental seq. overlap (%) | 22% | |
| Genomic Region |
Intergenic |
|
| Retrocopy Summary | RHOCP1, located on chr2:20447464-20447811, is a retrocopy of the parental gene RHOC. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes. |
| Gene Name | RHOC |
| Full Name | ras homolog family member C |
| Also known as | ARH9|ARHC|H9|RHOH9 |
| Coordinate | chr1:112701131-112707408 |
| Strand | - |
| Gene summary | This gene encodes a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility. The protein encoded by this gene is prenylated at its C-terminus, and localizes to the cytoplasm and plasma membrane. It is thought to be important in cell locomotion. Overexpression of this gene is associated with tumor cell proliferation and metastasis. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008] |
| >RHOCP1 |
| TCATGGCGGCCATCCGCAAGAAGCTGGTGGTGGTGGGCGACGGCGCGTGTGGCAAGACGTGCCTGCTGATCGTGTTCAGTAAGGACGAGTTCCCCGAGGTGTACGTGCCCACCGTCTTCGAGAACTATGTGGCCGACATTGAGGTGGACGGCAAGCAGGTGGAGCTGGCGCTGTGGGACACGGCGGGCCAGGAGGACTACGACCGCCTGCGGCCGCTCTCCTACCCGGACACCGACGTCATTCTCATGTGCTTCTCGGTGGACAGCCCGGACTCGCTGGAGAACATCCCCGAGAAGTGGGTCCCCGAGGTGAAGCACTTCTGTCCCAATGTGCCCATCATCCTGGTGG |
| >NM_001042678.2 |
| AGGGGATTGAAGGCTGGGCAGAGTCTGAGTCCACCCGGGTCGTGCTCCCCCCGCTCGCCCGGCTCCTCCGCAGTCCAGGAATCTCCCCGTGGCTCTCCCCGACCTGGAGGGGTGGACGCCCCTGGCCCCCAGTCCCCGGCCTGCGGAGGGGGCCGGTGGCTGCGGCCCTGCGCGGGGCCGGGGCGGGCCGAGCCAAGGGCCGCCCCCGGCCGACCCTCCCCCTGCCGGGCCCGCCCTCCCCGCCGCGGCGCTGGAGGAGGGCGGGGCGGGGCCCTGGGGTCAGTCTGAGCCTCCGGCACCGGCCGCGCAGCTGGAGGCGGCGGAGCGGAAGCCCCACCATGGCTGCAATCCGAAAGAAGCTGGTGATCGTTGGGGATGGTGCCTGTGGGAAGACCTGCCTCCTCATCGTCTTCAGCAAGGATCAGTTTCCGGAGGTCTACGTCCCTACTGTCTTTGAGAACTATATTGCGGACATTGAGGTGGACGGCAAGCAGGTGGAGCTGGCTCTGTGGGACACAGCAGGGCAGGAAGACTATGATCGACTGCGGCCTCTCTCCTACCCGGACACTGATGTCATCCTCATGTGCTTCTCCATCGACAGCCCTGACAGCCTGGAAAACATTCCTGAGAAGTGGACCCCAGAGGTGAAGCACTTCTGCCCCAACGTGCCCATCATCCTGGTGGGGAATAAGAAGGACCTGAGGCAAGACGAGCACACCAGGAGAGAGCTGGCCAAGATGAAGCAGGAGCCCGTTCGGTCTGAGGAAGGCCGGGACATGGCGAACCGGATCAGTGCCTTTGGCTACCTTGAGTGCTCAGCCAAGACCAAGGAGGGAGTGCGGGAGGTGTTTGAGATGGCCACTCGGGCTGGCCTCCAGGTCCGCAAGAACAAGCGTCGGAGGGGCTGTCCCATTCTCTGAGATCCCCAAGGCCTTTCCTACATGCCCCCTCCCTTCACAGGGGTACAGAAATTATCCCCCTACAACCCCAGCCTCCTGAGGGCTCCATGCTGAAGGCTCCCATTTTCAGTTCCCTCCTGCCCAGGACTGCATTGTTTTCTAGCCCCGAGGTGGTGGCACGGGCCCTCCCTCCCAGCGCTCTGGGAGCCACGCCTATGCCCTGCCCTTCCTCAGGGCCCCTGGGGATCTTGCCCCCTTTGACCTTCCCCAAAGGATGGTCACACACCAGCACTTTATACACTTCTGGCTCACAGGAAAGTGTCTGCAGTAGGGGACCCAGAGTCCCAGGCCCCTGGAGTTGTTTTCGGCAGGGGCCTTGTCTCTCACTGCATTTGGTCAGGGGGGCATGAATAAAGGCTACAGGCTCCAA |
| PMID - Link | Title |
|---|
